Quasiperiodic circus movement in a loop model of cardiac tissue: multistability and low dimensional equivalence.

abstract：:Modern models of cardiac membranes are often highly complex and computationally expensive, particularly when used in long simulations of spatially extended models of cardiac tissue. Therefore, there is a need for simpler membrane models that preserve the features of the complex models deemed important. This communicat...

journal_title：Annals of biomedical engineering

authors： Oliver RA,Krassowska W

更新日期：2005-07-01 00:00:00

abstract：:We attempted to estimate in living adherent epithelial alveolar cells, the degree of structural and mechanical heterogeneity by considering two individualized cytoskeleton components, i.e., a submembranous "cortical" cytoskeleton and a "deep" cytoskeleton (CSK). F-actin structure characterizing each CSK component was ...

journal_title：Annals of biomedical engineering

authors： Laurent VM,Fodil R,Cañadas P,Féréol S,Louis B,Planus E,Isabey D

更新日期：2003-11-01 00:00:00

abstract：:There has been considerable debate on the relative importance of biochemical stimuli and mechanical deformation in neutrophil adhesion in lung capillaries, a process observed following bacterial infection in the body. In contrast to venules, where the vessel diameter is larger than the leukocyte diameter (6-9 microm) ...

journal_title：Annals of biomedical engineering

authors： Pai A,Sundd P,Tees DF

更新日期：2008-04-01 00:00:00

abstract：:Overexpressed receptors, characteristic of many cancers, have been targeted by various researchers to achieve a more specific treatment for cancer. A common approach is to use the natural ligand for the overexpressed receptor as a cancer-targeting agent which can deliver a chemically or genetically conjugated toxic mo...

journal_title：Annals of biomedical engineering

authors： Yoon DJ,Liu CT,Quinlan DS,Nafisi PM,Kamei DT

更新日期：2011-04-01 00:00:00

abstract：:Intracellular calcium concentration and transmembrane potentials are two important measurements used to study the mechanisms of cardiac activity. Fluorescent dyes have been used to measure these separately but not simultaneously in cardiac tissue. Fluo-3 and Fluo-4 (a recently improved version of Fluo-3) have been use...

journal_title：Annals of biomedical engineering

authors： Johnson PL,Smith W,Baynham TC,Knisley SB

更新日期：1999-07-01 00:00:00

abstract：:Maintenance of movement accuracy relies on motor learning, by which prior errors guide future behavior. One aspect of this learning process involves the accurate generation of predictions of movement outcome. These predictions can, for example, drive anticipatory movements during a predictive-saccade task. Predictive ...

journal_title：Annals of biomedical engineering

authors： Wong AL,Shelhamer M

更新日期：2013-08-01 00:00:00

abstract：:Collagen is known to be a viscoelastic material and therefore is an important source of time dependent behavior in soft tissue. Though there are material models for soft tissue that rely on properties and structure of constituent collagen fibers, such models generally utilize only the elastic properties of collagen, a...

journal_title：Annals of biomedical engineering

authors： Bischoff JE

更新日期：2006-07-01 00:00:00

abstract：:Recent advances in fluorescence confocal endomicroscopy have allowed real-time identification of residual tumour cells on the walls of the cavity left by breast conserving surgery. However, it is difficult to systematically survey the surgical site because of the small imaging field-of-view of these probes, compounded...

journal_title：Annals of biomedical engineering

authors： Zuo S,Hughes M,Yang GZ

更新日期：2016-07-01 00:00:00

abstract：:Analysis and classification of esophageal motility records were investigated using signal processing and fuzzy-set pattern recognition techniques. A set of parameters has been extracted from the raw records and has previously been used as characterizing features. Improvements to these procedures were obtained by extra...

journal_title：Annals of biomedical engineering

authors： Abou-Chadi FE,Ezzat FA,Sif el-Din AA

更新日期：1994-01-01 00:00:00

abstract：:When cells and the matrix of a tissue remodel, the mechanical properties of the tissue do change. The mechanical properties are expressed by constitutive equations. In this article the remodeling of the constitutive equation of the pulmonary artery is studied. The remodeling was induced in a rat breathing a gas whose ...

journal_title：Annals of biomedical engineering

authors： Huang W,Delgado-West D,Wu JT,Fung YC

更新日期：2001-01-01 00:00:00

abstract：:Conventional nanoporous hydrogels often lead to slow cartilage deposition by MSCs in 3D due to physical constraints and requirement for degradation. Our group has recently reported macroporous gelatin microribbon (μRB) hydrogels, which substantially accelerate MSC-based cartilage formation in vitro compared to convent...

journal_title：Annals of biomedical engineering

authors： Barati D,Gegg C,Yang F

更新日期：2020-07-01 00:00:00

abstract：:This article presents an overview of time-resolved (lifetime) fluorescence techniques used in biomedical diagnostics. In particular, we review the development of time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) instrumentation and associated methodologies which allow in vivo char...

journal_title：Annals of biomedical engineering

authors： Marcu L

更新日期：2012-02-01 00:00:00

abstract：:Proper replacement or repair of damaged tendons or ligaments requires functionally engineered tissue that mimics their native mechanical properties. While tendon structure-function relationships are generally assumed, there exists little quantitative evidence of the roles of distinct tendon components in tendon functi...

journal_title：Annals of biomedical engineering

authors： Robinson PS,Lin TW,Jawad AF,Iozzo RV,Soslowsky LJ

更新日期：2004-07-01 00:00:00

abstract：:Arteries are composed of multiple constituents that endow the wall with proper structure and function. Many vascular diseases are associated with prominent mechanical and biological alterations in the wall constituents. In this study, planar biaxial tensile test data of elastase-treated porcine aortic tissue (Chow et ...

journal_title：Annals of biomedical engineering

authors： Zeinali-Davarani S,Chow MJ,Turcotte R,Zhang Y

更新日期：2013-07-01 00:00:00

abstract：:We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude vari...

journal_title：Annals of biomedical engineering

authors： Mitzner W,Gioia F,Weinmann GG,Robotham JL,Ehrlich W

更新日期：1987-01-01 00:00:00

abstract：:This paper presents two related methods for registering an image of an anatomical object with data from sensors arranged on the object. One method is described with reference to a test case involving a rectangular electrode plaque disposed on a heart surface, which is imaged with MRI. Data from the electrodes is fused...

journal_title：Annals of biomedical engineering

authors： Hopenfeld B,Ashikaga H,McVeigh ER

更新日期：2007-10-01 00:00:00

abstract：:A coculture of endothelial cells (ECs) and smooth muscle cells (SMCs), which mimics cellular interactions appearing in vivo, has been performed in studies on the relationship between atherogenesis and fluid shear stress conditions. Although healthy arteries in vivo consist of contractile phenotype SMCs, cultured cells...

journal_title：Annals of biomedical engineering

authors： Sakamoto N,Kiuchi T,Sato M

更新日期：2011-11-01 00:00:00

abstract：:Experimental and diagnostic procedures like distension of a balloon catheter, bougie, and esophagogastroduodenoscopy can induce shear deformation in the esophageal wall. However, the shear modulus of the esophagus is yet unknown. The aim of this study was to determine the esophageal shear modulus and its dependence on...

journal_title：Annals of biomedical engineering

authors： Yang J,Liao D,Zhao J,Gregersen H

更新日期：2004-09-01 00:00:00

abstract：:Thorax injuries mainly due to rib fractures have been associated with high rates of morbidity and mortality in motor vehicle crashes. Thoracic biomechanics has been studied extensively, but there are no robust biomechanical response targets for ribs that consider age, sex, body size, and vulnerability factors. The obj...

journal_title：Annals of biomedical engineering

authors： Kang YS,Kwon HJ,Stammen J,Moorhouse K,Agnew AM

更新日期：2021-02-01 00:00:00

abstract：:Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue engineering by directing chondrocytes to synthesize/degrade the extracellular matrix or promote inflammatory responses. The aim of this paper was to investigate a...

journal_title：Annals of biomedical engineering

authors： Neidlin M,Korcari A,Macheras G,Alexopoulos LG

更新日期：2018-02-01 00:00:00

abstract：:Microfluidic devices aim at miniaturizing, automating, and lowering the cost of chemical and biological sample manipulation and detection, hence creating new opportunities for lab-on-a-chip platforms. Recently, optofluidic devices have also emerged where optics is used to enhance the functionality and the performance ...

journal_title：Annals of biomedical engineering

authors： Bishara W,Isikman SO,Ozcan A

更新日期：2012-02-01 00:00:00

abstract：:A theoretical model is presented for describing the motion of a deformable cell encapsulating a Newtonian fluid and enclosed by an elastic membrane in tube flow. In the mathematical formulation, the interior and exterior hydrodynamics are coupled with the membrane mechanics by means of surface equilibrium equations, a...

journal_title：Annals of biomedical engineering

authors： Pozrikidis C

更新日期：2005-02-01 00:00:00

abstract：:We propose a multifrequency energy transmission scheme for annular phased arrays in deep-body hyperthermia. The problem of frequency dependent resonance effects reported in hyperthermia phantom calibration studies, leading to skewed energy deposition patterns and unwanted energy maxima (hot spots), is addressed by com...

journal_title：Annals of biomedical engineering

authors： Jacobsen S,Melandsø F

更新日期：2002-01-01 00:00:00

abstract：:The impedance of a monopolar electrode immersed in an environmental volume conductor consists of two parts; the impedance of the active electrode-electrolyte interface, and the resistance of the environmental conductor. Two studies were carried out to quantitate these components. First, impedance-frequency data were c...

journal_title：Annals of biomedical engineering

authors： Ragheb T,Riegle S,Geddes LA,Amin V

更新日期：1992-01-01 00:00:00

abstract：:We hypothesize that variations of body anthropometry, conjointly with the bone strength, determine the risk of hip fracture. To test the hypothesis, we compared, in a simulated sideways fall, the hip impact energy to the energy needed to fracture the femur. Ten femurs from elderly donors were tested using a novel drop...

journal_title：Annals of biomedical engineering

authors： Palanca M,Perilli E,Martelli S

更新日期：2020-11-12 00:00:00

abstract：:Radiation applied for therapy and diagnostics damages molecular/atomic couples of biotissues, bones being among them. As a result, electron peculiarities and mechanical behavior of the latter are altered. Correlation between strength of the irradiated bone and its electron features explored due to photo- and exoelectr...

journal_title：Annals of biomedical engineering

authors： Dekhtyar Y

更新日期：2001-12-01 00:00:00

abstract：:Additive manufacturing, also known as 3D printing, has emerged over the past 3 decades as a disruptive technology for rapid prototyping and manufacturing. Vat polymerization, powder bed fusion, material extrusion, and binder jetting are distinct technologies of additive manufacturing, which have been used in a wide va...

journal_title：Annals of biomedical engineering

authors： Trombetta R,Inzana JA,Schwarz EM,Kates SL,Awad HA

更新日期：2017-01-01 00:00:00

abstract：:Statistical methods are increasingly used in biomechanics for studying bone geometry, bone density distribution and function in the population. However, relating population-based bone variation to strain during activity is computationally challenging. Here, we describe a new method for calculating strain in a populati...

journal_title：Annals of biomedical engineering

authors： Ziaeipoor H,Taylor M,Martelli S

更新日期：2020-06-01 00:00:00

abstract：:Currently, there are no clinically available tools or applications which could predict osteoarthritis development. Some computational models have been presented to simulate cartilage degeneration, but they are not clinically feasible due to time required to build subject-specific knee models. Therefore, the objective ...

journal_title：Annals of biomedical engineering

authors： Mononen ME,Liukkonen MK,Korhonen RK

更新日期：2019-03-01 00:00:00

abstract：:Human stem cells hold significant potential for the treatment of various diseases. However, their use as a therapy is hampered because of limited understanding of the mechanisms by which they respond to environmental stimuli. Efforts to understand extracellular biophysical cues have demonstrated the critical roles of ...

journal_title：Annals of biomedical engineering

authors： Piroli ME,Jabbarzadeh E

更新日期：2018-06-01 00:00:00