Abstract:
:SecA is the dissociable ATPase subunit of the Escherichia coli preprotein translocase, and cycles in a nucleotide-modulated manner between the cytosol and the membrane. Overproduction of the integral subunits of the translocase, the SecY, SecE and SecG polypeptides, results in an increased level of membrane-bound SecA. This fraction of SecA is firmly associated with the membrane as it is resistant to extraction with the chaotropic agent urea, and appears to be anchored by SecYEG rather than by lipids. Topology analysis of this membrane-associated form of SecA indicates that it exposes a carboxy-terminal domain to the periplasmic face of the membrane.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
van der Does C,den Blaauwen T,de Wit JG,Manting EH,Groot NA,Fekkes P,Driessen AJdoi
10.1046/j.1365-2958.1996.d01-1712.xsubject
Has Abstractpub_date
1996-11-01 00:00:00pages
619-29issue
4eissn
0950-382Xissn
1365-2958journal_volume
22pub_type
杂志文章abstract::Metal ions are crucial trace elements for bacteria infecting the human host. The LraI (lipoprotein receptor-associated antigen I) transporter in Streptococcus spp. belongs to the superfamily of ABC transporters. The transporter consists of a lipoprotein, an ATP-binding protein and a hydrophobic integral membrane prote...
journal_title:Molecular microbiology
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abstract::Histidine kinases (HK) sense and transduce via phosphorylation events many intra- and extracellular signals in bacteria, archaea, slime moulds and plants. HK are also widespread in the fungal kingdom, but their precise roles in the regulation of physiological processes remain largely obscure. Expanding genomic resourc...
journal_title:Molecular microbiology
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更新日期:2008-12-01 00:00:00
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更新日期:2006-01-01 00:00:00
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journal_title:Molecular microbiology
pub_type: 杂志文章
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更新日期:1987-11-01 00:00:00
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journal_title:Molecular microbiology
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更新日期:1998-04-01 00:00:00
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更新日期:2007-01-01 00:00:00
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更新日期:2005-01-01 00:00:00
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更新日期:2012-05-01 00:00:00
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更新日期:2014-08-01 00:00:00
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更新日期:2011-09-01 00:00:00