Abstract：
OBJECTIVE AND METHODS:We reviewed records of 41 children with treated phenylketonuria (PKU) in order to evaluate hematopoiesis and the effect of iron and protein sufficiency. RESULTS:Six children (15%) were found to have anemia. Combined depletion of iron and protein stores was most likely to result in anemia, and two of the three children with this finding were anemic. Four children (10%) had evidence of iron deficiency without anemia (a precursor stage of iron deficiency anemia). Clinically significant iron depletion was found in older as well as younger children (well beyond the traditional infant/toddler deficient years). Plasma albumin was normal in all children and was not adequately sensitive to detect protein depletion sufficient to cause anemia or decreased growth. However, low plasma prealbumin (a more sensitive marker of protein sufficiency) correlated significantly with altered hematopoiesis or poor growth. CONCLUSION:Compared to non-affected individuals, children with treated PKU make fewer red cells that have normal volume but increased hemoglobin per cell, resulting in a lower calculated hematocrit when measured by electronic cell counting. In the presence of iron or protein depletion, anemia may result. Routine monitoring of ferritin, complete blood counts and prealbumin are recommended for children with PKU at all ages.
journal_name
J Am Coll Nutrjournal_title
Journal of the American College of Nutritionauthors
Arnold GL,Kirby R,Preston C,Blakely Edoi
10.1080/07315724.2001.10719016subject
Has Abstractpub_date
2001-02-01 00:00:00pages
65-70issue
1eissn
0731-5724issn
1541-1087journal_volume
20pub_type
杂志文章abstract：BACKGROUND:The blood glucose-lowering effects of β-glucan from oats and barley depend on the amounts consumed and their rheological properties. This has been recently challenged with growing evidence that the food matrix may also be an important factor in predicting its physiological response. OBJECTIVE:The objective ...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2013.875366
更新日期：2014-01-01 00:00:00
abstract：:America is experiencing a major obesity epidemic. The ramifications of this epidemic are immense since obesity is associated with chronic metabolic abnormalities such as insulin resistance, dyslipidemia, and heart disease. Reduced physical activity and/or increased energy intakes are important factors in this epidemic...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2005.10719460
更新日期：2005-06-01 00:00:00
abstract：:T-lymphocyte subpopulations were measured in the two major types of adult malnutrition, adult marasmus and kwashiorkor-like hypoalbuminemic malnutrition. The population of T-cells (T3) and the percentage of both helper (T4) and suppressor (T8) T-cells were significantly (P less than .05) decreased in patients with kwa...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1986.10720158
更新日期：1986-01-01 00:00:00
abstract：:There is an increased requirement for nutrients in normal pregnancy, not only due to increased demand, but also increased loss. There is also an increased insulin-resistant state during pregnancy mediated by the placental anti-insulin hormones estrogen, progesterone, human somatomammotropin; the pituitary hormone prol...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1996.10718560
更新日期：1996-02-01 00:00:00
abstract：:The tenth anniversary for the determination of magnesium in MBC shows progress, but fundamental questions are still unanswered. Uniformity of the methodology for the assay and the units for reporting the result is a key factor for the validity and comparability of results. There is relatively good agreement among inve...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1987.10720166
更新日期：1987-04-01 00:00:00
abstract：BACKGROUND:Cost-effectiveness of calcium supplementation depends not only on the cost of the product but on the efficiency of its absorption. Published cost-benefit analyses assume equal bioavailability for all calcium sources. Some published studies have suggested that there are differences in both the bioavailability...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.2001.10719038
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:The present study evaluated the effects of repeated-sprint training in normobaric hypoxia and β-alanine supplementation (BA) on aerobic and anaerobic performance in recreationally active men. METHODS:Participants were randomly assigned to one of the following groups: normoxia/β-alanine (NB, n = 11), normoxia...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1080/07315724.2018.1475269
更新日期：2019-02-01 00:00:00
abstract：UNLABELLED:Dietary recommendations for the treatment of hypercholesterolemia (HC) emphasize stepwise reductions in fat intake, but there is no agreement on what lower limit is desirable or achievable. These recommendations have applied broadly to persons with HC alone, as well as to those with a combined elevation in t...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.1991.10718169
更新日期：1991-10-01 00:00:00
abstract：:The lack of prevention of noncommunicable diseases (NCDs) has caused an increase in the mortality rate including conditions such as chronic kidney disease (CKD) and liver disease (LD). The high complexity of CKD and LD results in alterations in the metabolism of carbohydrates, proteins, and lipids. One of the changes ...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1810171
更新日期：2020-12-10 00:00:00
abstract：:No single study or avenue of investigation can resolve the scientific controversies that entangle efforts to determine the effects of specific nutrients on medical conditions. To reach consensus in this area requires a substantial body of plausible, reproducible and consistent data from various investigative approache...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1999.10718904
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVE:This study was launched to determine comparative effects of corn oil (CO), safflower oil (SO), fish oil (FO) and palm oil (PO) on carnitine status and ethanol metabolism in rats. METHODS:Twenty-four male Sprague-Dawley rats (300 g bw) were randomly divided into four groups (n = 6) and fed a semisynthetic die...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2002.10719215
更新日期：2002-06-01 00:00:00
abstract：OBJECTIVE:Sitosterolemia is a genetic disorder characterized by an increased plasma plant sterol concentration due to enhanced sterol absorption coupled with reduced steroid excretion. The purpose of the present investigation was two-fold; first to assess the effects of a "basal" low sitosterol metabolic diet on plasma...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：BACKGROUND:The objective of this study was to identify an association among dietary components, iron, and inflammatory status among adolescent girls. METHOD:Dietary information for 85 adolescent girls was collected through food frequency questionnaires. Biomarkers of iron and inflammatory status were analyzed. RESULT...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2018.1492470
更新日期：2019-03-01 00:00:00
abstract：:The paper "Combating COVID-19 and Building Immune Resilience: A Potential Role for Magnesium Nutrition?" by TC Wallace, which was published in the Journal of the American College of Nutrition highlights the importance of adequate magnesium (Mg) supply in relation to COVID-19. Wallace notes that Mg deficiency is associ...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1816230
更新日期：2020-10-16 00:00:00
abstract：:Objective: To assess whether the nutritional risk classified by StrongKids is associated with anemia and inflammation (total leukocytes and C-reactive protein (CRP)), as well as to compare the ability of StrongKids with anthropometry in identifying these changes in hospitalized pediatric patients.Methods: Cross-sectio...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1750072
更新日期：2020-04-13 00:00:00
abstract：:The age at which children suffering from classical phenylketonuria can safely discontinue their dietary therapy has been constantly disputed over the past decades. Recently, most phenylketonuria centers have begun to recommend a life-long diet, especially for female patients. Male patients are also advised to continue...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1994.10718402
更新日期：1994-06-01 00:00:00
abstract：:Since the discovery in 1929 that certain polyunsaturated fatty acids (PUFA) are essential for life and health, intense investigation has revealed the multiplicity of members in each of several families of PUFA, no two of which are equivalent. The quantified nutrient requirements for the essential dietary precursors of...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1986.10720125
更新日期：1986-01-01 00:00:00
abstract：:The complex interactions between the diet, gut microbiome, and host characteristics that provide a functional benefit to the host are an area of great interest and current exploration in the nutrition and health science community. New technologies are available to assess mechanisms that may explain these functional be...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2016.1257961
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:In vitro and animal studies suggest that antitumor effect of chemotherapeutic agents may be enhanced by antioxidants. Therefore, we initiated a clinical study to test the efficacy of high-dose multiple antioxidants (vitamins C, E and beta carotene) as an adjunct to chemotherapy (paclitaxel and carboplatin) in...
journal_title：Journal of the American College of Nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1080/07315724.2005.10719438
更新日期：2005-02-01 00:00:00
abstract：:Objective: We assessed the acute effect of beetroot extract intake on cardiovascular and autonomic recovery subsequent to strength exercise.Methods: This is a crossover, randomized, double-blind and placebo-controlled trial. We assessed 16 subjects but only 12 healthy male adults completed the two protocols in two ran...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1774441
更新日期：2020-05-29 00:00:00
abstract：:Foodstuffs produced and/or purchased locally were analyzed for Se. The effect of income and gender on Se intake and status of Utah County residents was evaluated by measurement of the following indicators: erythrocyte (RBC) and plasma Se concentration, and activity of Se-glutathione peroxidase (Se-GSH-Px) (EC 1.11.1.9...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1988.10720233
更新日期：1988-04-01 00:00:00
abstract：BACKGROUND:Vitamin D deficiency was associated with total mortality in previous epidemiological studies. Little is known about the effects of dietary vitamin D intake on mortality. We examined the association between mid-life dietary vitamin D intake and 45-year total mortality. METHODS:The Honolulu Heart Program is a...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2013.875363
更新日期：2014-01-01 00:00:00
abstract：:Dietary guidelines have broad implications for the health of individuals and populations. Increasingly, government agencies and medical organization that issue guidelines have pursued evidence-based approaches. These approaches emphasize a comprehensive, critical, and explicit examination of the scientific evidence th...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2006.10719578
更新日期：2006-06-01 00:00:00
abstract：:Abnormalities of the vascular endothelium contribute to all stages of atherosclerosis from lesion development to clinical cardiovascular disease events. Recognized risk factors, including diabetes mellitus, hypertension, dyslipidemia, cigarette smoking, and sedentary lifestyle are associated with endothelial dysfuncti...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.2007.10719625
更新日期：2007-08-01 00:00:00
abstract：:ABSTACTAim: The present study aimed to investigate the effect of rose sirup and marigold powder on the physicochemical properties, bioactive potential, sensory acceptability and storage life of the nutricereals (finger millet, oats) and milk-based functional beverage (FB).Method: Preliminary trials were performed usin...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2020.1744487
更新日期：2020-03-24 00:00:00
abstract：OBJECTIVE:This study was designed with two aims: 1) to determine if the coronary artery bypass graft (CABG) procedure alters plasma vitamin E and C concentrations of adult patients through repeated determinations of vitamin levels at time points before, during and following CABG, and 2) to assess whether plasma vitamin...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1998.10718742
更新日期：1998-04-01 00:00:00
abstract：:Objective: The aim of this study was to evaluate the effects of Mediterranean diet on weight loss in a large population in a municipality setting.Methods: A 6-month nutritional intervention was implemented in 50 randomly selected municipalities in Greece. In each municipality, approximately 180 overweight or obese pat...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2019.1660928
更新日期：2020-05-01 00:00:00
abstract：:Patients who appear to respond best to high branched-chain amino acid (BCAA) solutions have been previously described by objective measurements such as total urinary nitrogen (TUN) excretion, oxygen consumption index (O2Cl), plasma lactate, plasma pyruvate, plasma glucose (PG) and urinary 3-methylhistidine. Use of the...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.1992.10718192
更新日期：1992-02-01 00:00:00
abstract：:To assess whether antioxidants may reduce the risk of cancer, we reviewed the epidemiologic literature from 1985 through 1993. We assessed the separate relationships of three antioxidants (carotenoids, vitamin C, and vitamin E) with six sites of cancer (lung, upper aerodigestive tract, uterine cervix, colon, breast, p...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章,评审
doi：10.1080/07315724.1995.10718532
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND:Premature infants require high intakes of Ca and P to mimic fetal accretion rates. With the current phosphate salt used, adequate amounts cannot be provided due to the precipitation of Ca and P in TPN solutions. OBJECTIVE:To compare monobasic potassium phosphate (monobasic regimen) and monobasic plus dibasi...
journal_title：Journal of the American College of Nutrition
pub_type： 杂志文章
doi：10.1080/07315724.2006.10719517
更新日期：2006-02-01 00:00:00
