Ion transport in rat antral mucosa in vitro: general characteristics.

abstract：:Changes in the Young elasticity modulus in perpendicular direction to the membrane surface E perpendicular, in the coefficient of dynamic viscosity eta, in the electric capacitance C, in the surface charge U1, in the conductivity g and in the coefficient of non-linearity beta of current-voltage characteristic caused b...

journal_title：General physiology and biophysics

authors： Hianik T,Zórad S,Kavecanský J,Macho L

更新日期：1987-04-01 00:00:00

abstract：:Tissue intermittent hypoxia (IH) occurs in obstructive sleep apnea, sickle cell anemia, physical exercise and other conditions. Poor gas solubility and slow diffusion through culture media hampers mimicking IH-induced transitions of O(2) in vitro. We aimed to develop a system enabling exposure of cultured cells to IH ...

journal_title：General physiology and biophysics

authors： Polak J,Studer-Rabeler K,McHugh H,Hussain MA,Shimoda LA

更新日期：2015-07-01 00:00:00

abstract：:The upregulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) was reported to be involved in regulating the levels of inflammatory markers and apoptosis in macrophages. This study aims to investigate the function and regulation of PCSK9 in myocardial ischaemia. The results of our study showed dramatically ...

journal_title：General physiology and biophysics

authors： Yang CL,Zeng YD,Hu ZX,Liang H

更新日期：2020-03-01 00:00:00

abstract：:Arachidonic, linolenic and linoleic acids decreased the binding of the m-cholinergic antagonist [3H] QNB and did not affect the ratio of high to low affinity binding sites to the agonist carbamoylcholine in rat brain synaptic membranes. In the presence of arachidonic acid, SH-reagent N-ethylmaleimide acquired the abil...

journal_title：General physiology and biophysics

authors： Okun IM,Merezhinskaya NV,Rakovich AA,Volkovets TM,Aksentsev SL,Konev SV

更新日期：1986-06-01 00:00:00

abstract：:Limited numbers of studies include research of microvibration therapy in experimental models. We examined effects of chronic vibroacustic-microvibration treatment on haemodynamics and anti-oxidative defense in experimental hypertension. Study was performed on chronically treated hypertensive and normotensive Wistar ra...

journal_title：General physiology and biophysics

authors： Miloradović Z,Mihailović-Stanojević N,Jovović Đ,Ivanov M,Vajić UJ,Karanović D,Grujić Milanović J

更新日期：2015-01-01 00:00:00

abstract：:Maternal milk is a significant source of hormones and other bioactive substances. They might be involved either in the control of mammary gland function or in the regulation of growth and development of the neonate. Atriopeptin (atrial natriuretic factor, ANF) is a peptide with strong diuretic, natriuretic and vasorel...

journal_title：General physiology and biophysics

authors： Jezová D,Tokarev D,Kostálová L,Strbák V

更新日期：1996-08-01 00:00:00

abstract：:The role of viscosity in coupling between chemical reaction (complex formation) and diffusion in membranes has been investigated. The Fick law was replaced by the momentum balance equation with the viscous term. The irreversible thermodynamics admits coupling of the chemical reaction rate with the gradient of velocity...

journal_title：General physiology and biophysics

authors： Gałdzicki Z,Miekisz S

更新日期：1984-04-01 00:00:00

abstract：:The mechanisms underlying the renoprotective effect for remote limb ischemic preconditioning (rIPC) against renal ischemia/reperfusion injury need further elucidation. In our work, one hundred and twenty male Sprague Dawley rats were randomized into 3 groups; sham, I/R group (left renal 45 min ischemia) and rIPC (as I...

journal_title：General physiology and biophysics

authors： Hussein AM,Harraz AM,Awadalla A,Barakat N,Khater S,Shokeir AA

更新日期：2016-01-01 00:00:00

abstract：:A model for the dynamics of quasi-1D lipid structures in biological membranes is proposed. The model takes into account interactions between the lipid heads and hydro-carbon chains, the description of their relaxation dynamics being based on the phenomenological Ginzburg-Landau approach. It is shown that in lateral li...

journal_title：General physiology and biophysics

authors： Kadantsev VN,Tverdislov VA,Yakovenko LV,Kadantsev VV

更新日期：1997-12-01 00:00:00

abstract：:We studied the involvement of O2, pH and low molecular thiols in H2S-induced decomposition of S-nitrosoglutathione (GSNO). The GSNO decomposition - •NO release was evaluated by UV-VIS spectroscopy and Griess assay. The H2S donor Na2S was used. O2 slightly increased, but was not necessary for the H2S-induced GSNO decom...

journal_title：General physiology and biophysics

authors： Grman M,Misak A,Jacob C,Tomaskova Z,Bertova A,Burkholz T,Docolomansky P,Habala L,Ondrias K

更新日期：2013-09-01 00:00:00

abstract：:Hyperbaric oxygen treatment (HBO) could transiently reverse hypoxia during acute myocardial infarction (AMI). In order to evaluate whether early HBO can identify viable segments after AMI, improvement of wall motion score index (WMSI) after HBO was compared to dobutamine stress echocardiography (DSE). Thirty-one patie...

journal_title：General physiology and biophysics

authors： Dekleva M,Ostojic M,Neskovic A,Mazic S,Vlahovic A,Suzic Lazic J,Dekleva N

更新日期：2009-01-01 00:00:00

abstract：:Sleep is considered as a physiological regulator in the body. Gamma-aminobutyric acid (GABA) is a neurotransmitter that modulates sleep and affects cardiac functions. We evaluated effects of acute sleep deprivation (SD) on cardiac hemodynamic parameters, expression of pro-inflammatory cytokines, and Heat shock protein...

journal_title：General physiology and biophysics

authors： Parsa H,Faghihi M,Kardar GA,Imani A

更新日期：2018-05-01 00:00:00

abstract：:A number of computational methods for the description of the ligand-receptor interaction that were developed in the past decade are reviewed in this paper. The central two sections introduce the methods that are already established as useful tools for the qualitative and quantitative description of ligand-receptor com...

journal_title：General physiology and biophysics

authors： Hornák V,Dvorský R,Sturdík E

更新日期：1999-09-01 00:00:00

abstract：:Homocysteine (Hcys) may be implicated in different diseases, especially in cardiovascular illnesses. The most reactive form of Hcys is its cyclic thioester-homocysteine thiolactone (HTL), which is formed in plasma and represents up to 0.29% of plasma total Hcys. Recently, it has been observed that Hcys and HTL may mod...

journal_title：General physiology and biophysics

authors： Olas B,Kołodziejczyk J,Malinowska J

更新日期：2010-06-01 00:00:00

abstract：:The inhibition of sodium and potassium currents in frog myelinated fibres by ajmaline (AM) and its quaternary derivative, N-propyl ajmaline (NPA), depends on voltage-clamp pulses and the state of channel gating mechanisms. The permanently charged NPA and protonated AM interact only (or mainly) with open channels, whil...

journal_title：General physiology and biophysics

authors： Khodorov BI,Zaborovskaya LD

更新日期：1983-08-01 00:00:00

abstract：:PC12 cells differentiated under the influence of the neuronal growth factor (NGF) serve as a model of both sympathetic neurons and chromaffin cells. NGF-induced differentiation critically depends on elevated intracellular calcium concentration. Main pathway for Ca²⁺ entry in excitable cells is represented by voltage-d...

journal_title：General physiology and biophysics

authors： Lichvárová L,Lacinová Ľ

更新日期：2015-04-01 00:00:00

abstract：:This study investigated time-dependent variations in the activities of adenosine deaminase (ADA), an adenosine-metabolizing enzyme, and myeloperoxidase (MPO), an oxidation reaction-catalyzing enzyme, in control and streptozotocin (STZ)-induced diabetic rat liver. The animals were sacrificed at six different times of d...

journal_title：General physiology and biophysics

authors： Uluoglu C,Cimen B,Ozbey G,Karasu C,Durakoglugil DB,Gunes A,Turkozkan N,Zengil H

更新日期：2008-03-01 00:00:00

abstract：:Recent research has supported a potential role of immune pathology in the etiopathogenesis of schizophrenic. In the CNS various viruses were identified in the brains of schizophrenic patients. Pro-inflammatory cytokines were found to be associated with the stage of disease. Microglial cells were reported to be activat...

journal_title：General physiology and biophysics

authors： Rothermundt M,Ahn JN,Jörgens S

更新日期：2009-01-01 00:00:00

abstract：:The membrane lipid and fatty acid compositions of red blood cells from a paramyotonia patient were investigated. Cholesterol and total phospholipid contents in paramyotonia were not different from control. Only the sphingomyelin content was lower, and thus the molar ratio of phosphatidylcholine/sphingomyelin was highe...

journal_title：General physiology and biophysics

authors： Szymanska G,Marx A,Melzner I,Sarzala MG,Rüdel R

更新日期：1986-04-01 00:00:00

abstract：:This study examines the effects of a 2.1-GHz WCDMA-modulated microwave (MW) radiation on apoptotic activity and mitochondrial membrane potential (ΔΨm) in MCF-7 cells. The cells were exposed to the MW at a specific absorption rate (SAR) of 0.528 W/kg for 4 or 24 h. The antiproliferative effect of MW exposure was determ...

journal_title：General physiology and biophysics

authors： Esmekaya MA,Canseven AG,Kayhan H,Tuysuz MZ,Sirav B,Seyhan N

更新日期：2017-04-01 00:00:00

abstract：:The left and right ventricles fulfill different role in heart function. Here we compare chamber specific changes in local catecholamine concentrations; gene expression and the receptor protein amount of all three β-adrenoceptors (β-AR) in rat right heart ventricles exposed to acute (1 session) and repeated (7 sessions...

journal_title：General physiology and biophysics

authors： Tillinger A,Novakova M,Krizanova O,Kvetnansky R,Myslivecek J

更新日期：2014-01-01 00:00:00

abstract：:Lidocaine, a use-dependent Na(+) channel blocker, paradoxically evokes neural activation in the slowly adapting stretch receptor organ of crayfish at 5-10 mmol/l concentration. For elucidating the underlying mechanisms of this paradoxical effect, a series of conventional electrophysiological experiments were performed...

journal_title：General physiology and biophysics

authors： Keceli MB,Purali N

更新日期：2007-03-01 00:00:00

abstract：:The effect of binding of an antitumour drug cis-diamminedichloroplatinum(II) (cis-[Pt(NH3)2Cl2]) to DNA on cutting effectiveness of BamHI, EcoRI, and SalI restriction endonucleases was quantitatively determined. The platinum complex inhibits the cleavage of plasmid pHC624 DNA linearized by BglI restrictase. From the p...

journal_title：General physiology and biophysics

authors： Balcarová Z,Mrázek J,Kleinwächter V,Brabec V

更新日期：1992-12-01 00:00:00

abstract：:Fractal analysis was applied to images of photochemical lignin polymer obtained using scanning tunneling microscope. We studied the polymer obtained in vitro by ionic mechanism through UV radiation--induced polymerization. The analysis showed the regularity of the lignin-like polymer at different levels of organizatio...

journal_title：General physiology and biophysics

authors： Radotić K,Tasić M,Jeremić M,Budimlija Z,Simić-Krstić J,Polzović A,Bozović Z

更新日期：2001-03-01 00:00:00

abstract：:The aim of the study was to compare the effect of hemophane and polysulfone membranes on the phagocyte-derived production of reactive oxygen species (ROS) as well as on neutrophil CD11b and CD62L expression in patients undergoing regular hemodialysis. The effects of hemodialysis membranes were also studied in in vitro...

journal_title：General physiology and biophysics

authors： Kubala L,Cíz M,Soska V,Cerný J,Lojek A

更新日期：2002-12-01 00:00:00

abstract：:In the present work have been made some modifications of Münch's model, which concerns the explanation of biophysical bases of the problem of transport of water and assimilates. Then, by using the thermodynamic formalism of Kedem and Katchalsky (1958), we have made a mathematical description of the model. On this basi...

journal_title：General physiology and biophysics

authors： Kargol M

更新日期：1994-02-01 00:00:00

abstract：:The aim of the study was to examine the effects of epidermal growth factor (EGF) on ram sperm traits following hypothermic storage. Fresh ram ejaculates were diluted in Triladyl extender, pooled and divided into groups according to EGF doses added (0, 100, 200 or 400 ng/ml). Following 72-96 h storage at 4ºC, the sperm...

journal_title：General physiology and biophysics

authors： Makarevich AV,Spalekova E,Olexikova L,Lukac N,Kubovicova E,Hegedusova Z

更新日期：2011-01-01 00:00:00

abstract：:The effects of pentoxifylline (PTX) on intracellular accumulation of doxorobicin (DOX), DOX cytotoxicity and expression of Pgp in multidrug resistant L1210/VCR cell line were investigated. PTX (100 mg/l) was able to enhance the DOX accumulation in resistant cells. The maximum intracellular levels of DOX were reached a...

journal_title：General physiology and biophysics

authors： Drobná Z,Stein U,Walther W,Barancík M,Breier A

更新日期：2002-03-01 00:00:00

abstract：:Results of studies on the modulation of skeletal muscle contraction by phosphorylation of myosin regulatory light chains and by exchange of magnesium for calcium in myosin heads were reviewed. The polarized fluorescence method was used in these studies, and conformational changes of contractile proteins accompanying m...

journal_title：General physiology and biophysics

authors： Borovikov YuS,Kakol I

更新日期：1991-06-01 00:00:00

abstract：:Photon emissions were measured at ambient temperature (21°C) in complete darkness once per min from cultures of 10(6) cells during the 12 h following removal from 37°C. The energy of emission was about 10(-20) J/s/cell. Of 8 different cell lines, B16-BL6 (mouse melanoma cells) demonstrated the most conspicuous emissio...

journal_title：General physiology and biophysics

authors： Dotta BT,Buckner CA,Cameron D,Lafrenie RF,Persinger MA

更新日期：2011-09-01 00:00:00