Segregation of EAV-HP ancient endogenous retroviruses within the chicken population.

Abstract:

:Avian leukosis virus subgroup J (ALV-J), an exogenous avian retrovirus, is thought to have evolved by recombination with the highly identical env gene of the endogenous avian retrovirus EAV-HP. Embryonic expression of EAV-HP env has been suggested to be associated with the induction of immunological tolerance, a feature observed in a significant proportion of meat-type chickens infected with ALV-J. In support of this hypothesis, we demonstrate that EAV-HP loci, some of which could be associated with tolerance, are still segregating within the chicken population.

journal_name

J Virol

journal_title

Journal of virology

authors

Sacco MA,Venugopal K

doi

10.1128/JVI.75.23.11935-11938.2001

subject

Has Abstract

pub_date

2001-12-01 00:00:00

pages

11935-8

issue

23

eissn

0022-538X

issn

1098-5514

journal_volume

75

pub_type

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