Autophagy and the effects of its inhibition on varicella-zoster virus glycoprotein biosynthesis and infectivity.

abstract：UNLABELLED:Transmission of chronic wasting disease (CWD) between cervids is influenced by the primary structure of the host cellular prion protein (PrP(C)). In white-tailed deer, PRNP alleles encode the polymorphisms Q95 G96 (wild type [wt]), Q95 S96 (referred to as the S96 allele), and H95 G96 (referred to as the H95 ...

journal_title：Journal of virology

authors： Duque Velásquez C,Kim C,Herbst A,Daude N,Garza MC,Wille H,Aiken J,McKenzie D

更新日期：2015-12-01 00:00:00

abstract：:We constructed a matched set of plasmids to investigate the interactions of essential core sequences of the simian virus 40 replication origin with flanking regulatory sequences. Deletions of either T-antigen-binding region I or the 21-base-pair repeated promoter elements reduced replication to 50 to 70% of wild-type ...

journal_title：Journal of virology

authors： DeLucia AL,Deb S,Partin K,Tegtmeyer P

更新日期：1986-01-01 00:00:00

abstract：:A temperature-sensitive mutant of adenovirus 31 was defective in formation of the DNA replication complex, suggesting the existence of a virus-coded protein necessary for the complex-formation. ...

journal_title：Journal of virology

authors： Suzuki E,Shimojo H

更新日期：1974-02-01 00:00:00

abstract：:The protein (p59rel) encoded by the transforming gene of reticuloendotheliosis virus strain T (REV-T) has been identified in REV-T-transformed avian lymphoid cells by using antisera raised against synthetic peptides whose sequences were derived from three nonoverlapping regions of v-rel (N. R. Rice, T. D. Copeland, S....

journal_title：Journal of virology

authors： Simek SL,Stephens RM,Rice NR

更新日期：1986-07-01 00:00:00

abstract：:Formation of a six-helix bundle comprised of three C-terminal heptad repeat regions in antiparallel orientation in the grooves of an N-terminal coiled-coil is critical for promotion of membrane fusion by paramyxovirus fusion (F) proteins. We have examined the effect of mutations in four residues of the N-terminal hept...

journal_title：Journal of virology

authors： West DS,Sheehan MS,Segeleon PK,Dutch RE

更新日期：2005-02-01 00:00:00

abstract：:Based on previous structural and functional studies, a potential receptor-binding site composed of residues that form a pocket at one end of the two long antiparallel helices in the receptor-binding domain of Friend 57 murine leukemia virus envelope protein (RBD) has been proposed. To test this hypothesis, directed su...

journal_title：Journal of virology

authors： Davey RA,Zuo Y,Cunningham JM

更新日期：1999-05-01 00:00:00

abstract：:Valproic acid (VPA) is a short-chain fatty acid commonly used for treatment of neurological disorders. As VPA can interfere with cellular lipid metabolism, its effect on the infection of cultured cells by viruses of seven viral families relevant to human and animal health, including eight enveloped and four nonenvelop...

journal_title：Journal of virology

authors： Vázquez-Calvo A,Saiz JC,Sobrino F,Martín-Acebes MA

更新日期：2011-02-01 00:00:00

abstract：:Nucleotide sequence analysis of the long terminal repeat (LTR) of the integrated simian sarcoma virus showed that the simian sarcoma virus LTR comprised 504 nucleotides with an inverted repeat of seven bases at its 5' and 3' termini. At the site of simian sarcoma virus integration, cellular flanking sequences adjacent...

journal_title：Journal of virology

authors： Devare SG,Reddy EP,Law JD,Aaronson SA

更新日期：1982-06-01 00:00:00

abstract：:WUH4 is a highly pathogenic North American porcine reproductive and respiratory syndrome virus (PRRSV). Unlike previous PRRSV isolates, which were mainly recovered from sera or tissues, WUH4 was isolated from a piglet stool sample. Here we announce its complete genome sequence. ...

journal_title：Journal of virology

authors： Song T,Fang L,Zeng S,Li B,Chen H,Xiao S

更新日期：2012-04-01 00:00:00

abstract：:The adjuvant effects of cytokines in humoral and cell-mediated immunity to herpes simplex virus type 1 (HSV-1) have been examined in mice using HSV-1 recombinant viruses expressing murine interleukin-2 (IL-2), IL-4, or gamma interferon (IFN-gamma) gene. Groups of naive BALB/c mice were immunized intraperitoneally with...

journal_title：Journal of virology

authors： Osorio Y,Ghiasi H

更新日期：2003-05-01 00:00:00

abstract：:Epstein-Barr virus (EBV) in vivo is known to establish persistent infection in resting, circulating memory B cells and to productively replicate in plasma cells. Until now, the molecular mechanism of how EBV switches from latency to lytic replication in vivo was not known. Here, we report that the plasma cell differen...

journal_title：Journal of virology

authors： Sun CC,Thorley-Lawson DA

更新日期：2007-12-01 00:00:00

abstract：UNLABELLED:Human noroviruses are icosahedral single-stranded RNA viruses. The capsid protein is divided into shell (S) and protruding (P) domains, which are connected by a flexible hinge region. There are numerous genetically and antigenically distinct noroviruses, and the dominant strains evolve every other year. Vacc...

journal_title：Journal of virology

authors： Koromyslova AD,Hansman GS

更新日期：2015-03-01 00:00:00

abstract：:Protein P4, an early protein of double-stranded RNA bacteriophage phi 6, is a component of the virion-associated RNA polymerase complex and possesses a nucleoside triphosphate (NTP) phosphohydrolase activity. We have produced and characterized a panel of 20 P4-specific monoclonal antibodies. Epitope mapping using trun...

journal_title：Journal of virology

authors： Ojala PM,Juuti JT,Bamford DH

更新日期：1993-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) is an important human pathogen associated with chronic liver disease. Recently, based on a genotype 2a isolate, tissue culture systems supporting complete replication and infectious virus production have been developed. In this study, we used cell culture-produced infectious HCV to analyze the ...

journal_title：Journal of virology

authors： Tscherne DM,Jones CT,Evans MJ,Lindenbach BD,McKeating JA,Rice CM

更新日期：2006-02-01 00:00:00

abstract：:Gammaretroviruses, such as murine leukemia virus (MLV), are functionally distinguished from lentiviruses, such as human immunodeficiency virus, by their inability to infect nondividing cells. Attempts to engineer this property into MLV have been hindered by an incomplete understanding of early events in the viral life...

journal_title：Journal of virology

authors： Yu JH,Schaffer DV

更新日期：2006-09-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) primarily infect activated CD4(+) T cells but can infect macrophages. Surprisingly, ex vivo tetramer-sorted SIV-specific CD8(+) T cells that eliminated and suppressed viral replication in SIV-infected CD4(+) T cells failed to do so in SIV-infec...

journal_title：Journal of virology

authors： Vojnov L,Martins MA,Bean AT,Veloso de Santana MG,Sacha JB,Wilson NA,Bonaldo MC,Galler R,Stevenson M,Watkins DI

更新日期：2012-04-01 00:00:00

abstract：:NYVAC has been engineered as a safe, attenuated vaccinia virus (VV) vector for use in vaccination against a broad spectrum of pathogens and tumors. Due to the interest in NYVAC-based vectors as vaccines and current phase I/II clinical trials with this vector, there is a need to analyze the human host response to NYVAC...

journal_title：Journal of virology

authors： Guerra S,López-Fernández LA,Pascual-Montano A,Nájera JL,Zaballos A,Esteban M

更新日期：2006-01-01 00:00:00

abstract：:Immune precipitation with monospecific antiserum was employed to study the intracellular synthesis of viral glycoproteins gp85 and gp37. Labeled gp85 and gp37 were detected from lysates of cells transformed with Rous sacroma virus, strain B77, after long-term labeling with radioactive glucosamine or phenylalanine. Imm...

journal_title：Journal of virology

authors： Moelling K,Hayami M

更新日期：1977-06-01 00:00:00

abstract：:The mechanism by which simian virus 40 converts the abortive adenovirus type 7 infection of monkey cells into an efficient lytic infection has been investigated. Analysis of ribonucleic acid (RNA) synthesis during unenhanced and enhanced infection of monkey cells has shown that adenovirus RNA synthesized in the aborti...

journal_title：Journal of virology

authors： Fox RI,Baum SG

更新日期：1972-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a human herpesvirus capable of establishing a latent state in B lymphocytes. EBV's BZLF1 gene product plays a central role in regulating the switch from latency to productive infection. Here, we identify a sequence element, 5'-CAGGTA-3', called ZV, located at nucleotides -17 to -12 relative...

journal_title：Journal of virology

authors： Kraus RJ,Mirocha SJ,Stephany HM,Puchalski JR,Mertz JE

更新日期：2001-01-01 00:00:00

abstract：:A conjugate of Pseudomonas exotoxin and epidermal growth factor (PE-EGF) inhibits proteins synthesis in KB cells, and this inhibition is increased by adenovirus. Protein synthesis inhibition is dependent on the amount of adenovirus and PE-EGF used and the time of incubation of cells with these agents. With 1 microgram...

journal_title：Journal of virology

authors： Seth P,Fitzgerald DJ,Willingham MC,Pastan I

更新日期：1984-09-01 00:00:00

abstract：:The adenovirus (Ad) E4 ORF3 protein is both necessary and sufficient to reorganize a nuclear subdomain, the PML nuclear body (PML-NB), from punctate structures into elongated nuclear tracks. PML-NB disruption is recapitulated by a variety of DNA viruses that encode proteins responsible for compromising PML-NB integrit...

journal_title：Journal of virology

authors： Ullman AJ,Hearing P

更新日期：2008-08-01 00:00:00

abstract：:Type I interferon (IFN-I) inhibits the replication of different viruses. However, the effect of IFN-I on the human T-lymphotropic virus type 1 (HTLV-1) viral cycle is controversial. Here, we investigated the consequences of IFN-α addition for different steps of HTLV-1 and HTLV-2 infection. We first show that alpha int...

journal_title：Journal of virology

authors： Cachat A,Chevalier SA,Alais S,Ko NL,Ratner L,Journo C,Dutartre H,Mahieux R

更新日期：2013-12-01 00:00:00

abstract：:Some strains of the protozoan parasite genus Leishmania are persistently infected with single-segmented double-stranded RNA viruses, which are termed LRV. The function of these cytoplasmic viruses is unknown. In order to address the question of whether LRV affects the parasite's phenotype, pairs of isogenic LRV(+)-LRV...

journal_title：Journal of virology

authors： Widmer G

更新日期：1995-07-01 00:00:00

abstract：:Primary sympathetic neuronal cultures were maintained for up to 5 weeks after inoculation with herpes simplex virus (HSV) without evidence of viral infection. Upon deprivation of nerve growth factor, the cultures produced infectious HSV, indicating that the cultures harbored latent HSV. This study demonstrates a funct...

journal_title：Journal of virology

authors： Wilcox CL,Johnson EM Jr

更新日期：1987-07-01 00:00:00

abstract：:Cauliflower mosaic virus (CaMV) forms two types of inclusion bodies within infected plant cells: numerous virus factories, which are the sites for viral replication and virion assembly, and a single transmission body (TB), which is specialized for virus transmission by aphid vectors. The TB reacts within seconds to ap...

journal_title：Journal of virology

authors： Bak A,Gargani D,Macia JL,Malouvet E,Vernerey MS,Blanc S,Drucker M

更新日期：2013-11-01 00:00:00

abstract：:Hepatitis B virus (HBV) and woolly monkey hepatitis B virus (WMHBV) are primate hepadnaviruses that display restricted tissue and host tropisms. Hepatitis D virus (HDV) particles pseudotyped with HBV and WMHBV envelopes (HBV-HDV and WM-HDV) preferentially infect human and spider monkey hepatocytes, respectively, there...

journal_title：Journal of virology

authors： Barrera A,Guerra B,Notvall L,Lanford RE

更新日期：2005-08-01 00:00:00

abstract：:To study the expression of the Autographa californica nuclear polyhedrosis virus (AcNPV) genome, intracellular virus-specific proteins and mRNAs were pulsed-labeled, extracted, and analyzed at 6-h intervals during the replicative cycle. Most RNAs were detected between 12 and 24 h postinfection (p.i.), but many continu...

journal_title：Journal of virology

authors： Rohel DZ,Faulkner P

更新日期：1984-06-01 00:00:00

abstract：:We molecularly cloned unintegrated viral DNA of the BALB/c endogenous N-tropic and B-tropic murine leukemia retroviruses and in vitro passaged N-tropic Gross (passage A) murine leukemia retroviruses. Recombinant genomes were constructed in vitro by exchanging homologous restriction enzyme fragments from N- or B-tropic...

journal_title：Journal of virology

authors： Boone LR,Myer FE,Yang DM,Ou CY,Koh CK,Roberson LE,Tennant RW,Yang WK

更新日期：1983-10-01 00:00:00

abstract：:Fatal infection with the highly pathogenic Lassa virus (LASV) is characterized by extensive viral dissemination, indicating broad tissue tropism. The major cellular receptor for LASV is the highly conserved extracellular matrix receptor dystroglycan (DG). Binding of LASV depends on DG's tissue-specific posttranslation...

journal_title：Journal of virology

authors： Fedeli C,Torriani G,Galan-Navarro C,Moraz ML,Moreno H,Gerold G,Kunz S

更新日期：2018-02-12 00:00:00