Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo.

abstract：:The glycan shield of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) protein serves as a barrier to antibody-mediated neutralization and plays a critical role in transmission and infection. One of the few broadly neutralizing HIV-1 antibodies, 2G12, binds to a carbohydrate epitope consisting of an array...

journal_title：Journal of virology

authors： Luallen RJ,Lin J,Fu H,Cai KK,Agrawal C,Mboudjeka I,Lee FH,Montefiori D,Smith DF,Doms RW,Geng Y

更新日期：2008-07-01 00:00:00

abstract：:The viral membrane proteins M and E are the minimal requirements for the budding of coronavirus particles. Since the E protein occurs in particles only in trace amounts, the lateral interactions between the M proteins apparently generate the major driving force for envelope formation. By using coimmunoprecipitation an...

journal_title：Journal of virology

authors： de Haan CA,Vennema H,Rottier PJ

更新日期：2000-06-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is the first human virus found to encode many microRNAs. It is etiologically linked to nasopharyngeal carcinoma and EBV-associated gastric carcinoma. During the latent infection period, there are only a few EBV proteins expressed, whereas EBV microRNAs, such as the BamHI-A region rightward tra...

journal_title：Journal of virology

authors： Zheng X,Wang J,Wei L,Peng Q,Gao Y,Fu Y,Lu Y,Qin Z,Zhang X,Lu J,Ou C,Li Z,Zhang X,Liu P,Xiong W,Li G,Yan Q,Ma J

更新日期：2018-11-12 00:00:00

abstract：:We located a region of interstrain size variability in a short segment in an area at the right-hand end of the long unique sequence of the varicella-zoster viral genome. Varicella-zoster virus strains isolated in a district of Japan were classified into three groups on the basis of the size of this segment. Sequence c...

journal_title：Journal of virology

authors： Hondo R,Yogo Y

更新日期：1988-08-01 00:00:00

abstract：:Cloned avian leukosis viral DNAs were mutagenized in the long terminal repeat, in the leader sequence for env mRNA, and at the poly-env junction. The effect of these mutations in the viral DNA upon its ability to direct virus production or env mRNA synthesis was analyzed by microinjecting the mutant DNAs into chicken ...

journal_title：Journal of virology

authors： Pugatsch T,Stacey DW

更新日期：1982-08-01 00:00:00

abstract：:Poxviruses express proteins that limit host immune responses to infection. For example, the molluscum contagiosum virus MC160 protein inhibits tumor necrosis factor alpha (TNF-alpha)-induced NF-kappaB activation. This event correlates with MC160-induced IKK1 protein degradation, suggesting a mechanism for the above-me...

journal_title：Journal of virology

authors： Nichols DB,Shisler JL

更新日期：2009-04-01 00:00:00

abstract：:Small amounts of infectious simian virus 40 (SV40) were recovered from parental cultures of SV40-transformed human embryonic lung (WI38 Va13A) cells, from 12 primary clones, from 17 secondary clones, and from 18 tertiary clones. The cloning experiments demonstrated that the capacity for spontaneous virus production is...

journal_title：Journal of virology

authors： Dubbs DR,Kit S

更新日期：1971-10-01 00:00:00

abstract：:The strain of Newcastle disease virus (NDV(pi)) present in persistently infected L cells differed markedly from the Herts strain (NDV(0)) used to initiate the infection. NDV(pi) produced small plaques (less than 1 mm) in chick embryo cell cultures, whereas the wild type (NDV(0)) produced large plaques (2 to 3 mm). The...

journal_title：Journal of virology

authors： Thacore H,Youngner JS

更新日期：1969-09-01 00:00:00

abstract：:We have selected an HXB2 variant which can replicate in the presence of a neutralizing human serum. Sequencing of the gp120 region of the env gene from the variant and parental viruses identified a single amino acid substitution in the third conserved region of gp120 at residue 375 (AGT-->AAT, Ser-->Asn; designated 37...

journal_title：Journal of virology

authors： McKeating JA,Bennett J,Zolla-Pazner S,Schutten M,Ashelford S,Brown AL,Balfe P

更新日期：1993-09-01 00:00:00

abstract：:To study the tissue specificity of mouse mammary tumor virus (MMTV) gene expression, we developed two series of transgenic mice, containing the MMTV proviral DNA of mammary (GR) and kidney (C3H-K) origin. The expression pattern in the MMTV(GR) transgenic mice is very similar to that observed in infected animals, e.g.,...

journal_title：Journal of virology

authors： Rollini P,Billotte J,Kolb E,Diggelmann H

更新日期：1992-07-01 00:00:00

abstract：:Spontaneous deletion mutants of satellite bacteriophage P4 have been isolated and characterized. All of the deletions analyzed that were between 850 and 1,700 base pairs long are within the region nonessential for P4 lytic development; some of them cover the cII or the gop locus. ...

journal_title：Journal of virology

authors： Raimondi A,Donghi R,Montaguti A,Pessina A,Dehò G

更新日期：1985-04-01 00:00:00

abstract：UNLABELLED:Little is known about the antiviral response in mollusks. As in other invertebrates, the interferon signaling pathways have not been identified, and in fact, there is a debate about whether invertebrates possess antiviral immunity similar to that of vertebrates. In marine bivalves, due to their filtering act...

journal_title：Journal of virology

authors： Novoa B,Romero A,Álvarez ÁL,Moreira R,Pereiro P,Costa MM,Dios S,Estepa A,Parra F,Figueras A

更新日期：2016-08-12 00:00:00

abstract：:A cloned DNA copy of simian rotavirus SA11 genomic segment 10 was used to confirm the assignment of the nonstructural glycoprotein NCVP5 to this gene. Determination of the nucleotide sequence for gene 10 indicated that NCVP5 is 175 amino acids in length and has an N-terminal hydrophobic region with the characteristics...

journal_title：Journal of virology

authors： Both GW,Siegman LJ,Bellamy AR,Atkinson PH

更新日期：1983-11-01 00:00:00

abstract：:Viruses actively interact with host metabolism because viral replication relies on host cells to provide nutrients and energy. Vaccinia virus (VACV; the prototype poxvirus) prefers glutamine to glucose for efficient replication to the extent that VACV replication is hindered in glutamine-free medium. Remarkably, our d...

journal_title：Journal of virology

authors： Pant A,Cao S,Yang Z

更新日期：2019-06-14 00:00:00

abstract：:The E3 complex transcription unit of adenovirus encodes four major mRNAs (a, c, f, and h) and two minor (d and e) mRNAs with overlapping exons, alternative splice sites, and two polyadenylation sites, termed E3A (upstream) and E3B (downstream). mRNAs a and d use the E3A polyadenylation site, and mRNAs c, e, f, and h u...

journal_title：Journal of virology

authors： Brady HA,Scaria A,Wold WS

更新日期：1992-10-01 00:00:00

abstract：:Serial serum specimens from 22 herpes simplex virus (HSV)-seronegative recipients of an HSV type 2 (HSV-2) glycoprotein subunit vaccine were analyzed by radioimmunoprecipitation and polyacrylamide gel electrophoresis for the development of antibodies to HSV-2 gB, gD, and g80, a complex of gC and gE. Volunteers receive...

journal_title：Journal of virology

authors： Ashley R,Mertz G,Clark H,Schick M,Salter D,Corey L

更新日期：1985-11-01 00:00:00

abstract：:The alternating host cycle and persistent vector infection may constrain the evolution of arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK or mosquito cells, as well as in alternating (both) host cell passages. High and low multiplicities were used to examine the effect of de...

journal_title：Journal of virology

authors： Weaver SC,Brault AC,Kang W,Holland JJ

更新日期：1999-05-01 00:00:00

abstract：:The murine polyomavirus (Py) enters mouse fibroblasts and kidney epithelial cells via an endocytic pathway that is caveola-independent (as well as clathrin-independent). In contrast, uptake of simian virus 40 into the same cells is dependent on caveola. Following the initial uptake of Py, both microtubules and microfi...

journal_title：Journal of virology

authors： Gilbert JM,Goldberg IG,Benjamin TL

更新日期：2003-02-01 00:00:00

abstract：:Type C RNA virus(es) was readily released from primary lymphosarcoma cell cultures of WH/J rabbits after induction with halogenated pyrimidines. The virus contained an RNA-directed DNA polymerase and the p30 structural protein. The rabbit virus RNA-directed DNA polymerase and p30 protein shared antigenic homologies wi...

journal_title：Journal of virology

authors： Bedigian HG,Fox RR,Meier H

更新日期：1978-08-01 00:00:00

abstract：:High-risk human papillomaviruses (HPVs), including HPV-16 and HPV-18, are the causative agents of cervical carcinomas and are linked to several other tumors of the anogenital and oropharyngeal regions. The majority of HPV-induced tumors contain integrated copies of the normally episomal HPV genome that invariably reta...

journal_title：Journal of virology

authors： Kennedy EM,Kornepati AV,Goldstein M,Bogerd HP,Poling BC,Whisnant AW,Kastan MB,Cullen BR

更新日期：2014-10-01 00:00:00

abstract：:We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate infectious progeny virions and form a syncytium with neighbor...

journal_title：Journal of virology

authors： Wilson DW,Davis-Poynter N,Minson AC

更新日期：1994-11-01 00:00:00

abstract：:The DNA sequence of 3,240 nucleotides of the XbaI G fragment located in the unique long (UL) region of the equine herpesvirus 1 genome revealed two major open reading frames (ORFs) designated UL3 and UL4. The UL3 ORF of 470 amino acids (aa) maps at nucleotides (nt) 4450 to 3038 from the long terminus, and its predicte...

journal_title：Journal of virology

authors： Zhao Y,Holden VR,Harty RN,O'Callaghan DJ

更新日期：1992-09-01 00:00:00

abstract：:Human CD317 (BST-2/tetherin) is an intrinsic immunity factor that blocks the release of retroviruses, filoviruses, herpesviruses, and arenaviruses. It is unclear whether CD317 expressed endogenously in rodent cells has the capacity to interfere with the replication of the retroviral rodent pathogen murine leukemia vir...

journal_title：Journal of virology

authors： Goffinet C,Schmidt S,Kern C,Oberbremer L,Keppler OT

更新日期：2010-11-01 00:00:00

abstract：:The gD, gB, and gH/gL glycoprotein quartet constitutes the basic apparatus for herpes simplex virus (HSV) entry into the cell and fusion. gD serves as a receptor binding glycoprotein and trigger of fusion. The conserved gB and gH/gL execute fusion. Central to understanding HSV entry/fusion has become the dissection of...

journal_title：Journal of virology

authors： Avitabile E,Forghieri C,Campadelli-Fiume G

更新日期：2009-10-01 00:00:00

abstract：:The protein product of the v-myb oncogene of avian myeloblastosis virus, p48v-myb, differs structurally in several ways from its normal cellular homolog, p75c-myb. We demonstrated that the 11 specific amino acid substitutions found in two independent molecular clones of this virus were not required for the transformat...

journal_title：Journal of virology

authors： Stober-Grässer U,Lipsick JS

更新日期：1988-03-01 00:00:00

abstract：:PLC/PRF/5, a tissue culture cell line isolated from a human hepatocellular carcinoma and producing hepatitis B surface antigen, was studied for the presence of hepatitis B virus (HBV)-specific DNA and RNA. PLC/PRF/5 cell DNA accelerated the rate of reassociation of HBV [32P]DNA, and quantitative experiments indicated ...

journal_title：Journal of virology

authors： Marion PL,Salazar FH,Alexander JJ,Robinson WS

更新日期：1980-02-01 00:00:00

abstract：:We have previously demonstrated that open reading frame (ORF) 50 and ORF 57 encode transcriptional regulating genes in herpesvirus saimiri. ORF 50, a homolog of Epstein-Barr virus R protein, is a sequence-specific transactivator, whereas ORF 57 acts posttranscriptionally. In this report, we demonstrate that the ORF 57...

journal_title：Journal of virology

authors： Whitehouse A,Cooper M,Hall KT,Meredith DM

更新日期：1998-03-01 00:00:00

abstract：:Ribosomes from ghost-treated Escherichia coli can form in vitro initiation complexes but cannot translate added template RNA because of a defect in the 30S subunit; 16S rRNA is degraded. ...

journal_title：Journal of virology

authors： Simon M,Kennell D

更新日期：1974-11-01 00:00:00

abstract：:Varicella zoster virus (VZV) is a neurotropic alphaherpesvirus that causes chickenpox during primary infection and establishes latency in sensory ganglia. Infection of rhesus macaques (RM) with the homologous simian varicella virus (SVV) recapitulates hallmarks of VZV infection. We have shown that an antisense transcr...

journal_title：Journal of virology

authors： Meyer C,Kerns A,Haberthur K,Dewane J,Walker J,Gray W,Messaoudi I

更新日期：2013-02-01 00:00:00

abstract：:To dissect mechanisms of caprine arthritis-encephalitis lentivirus-induced arthritis, an undefined immunodominant viral glycoprotein, gp90 (G. C. Johnson, A. F. Barbet, P. Klevjer-Anderson, and T. C. McGuire, Infect. Immun. 41:657-665, 1983), was characterized. Monoclonal antibody to gp90 and specific antiserum to env...

journal_title：Journal of virology

authors： McGuire TC,Knowles DP Jr,Davis WC,Brassfield AL,Stem TA,Cheevers WP

更新日期：1992-05-01 00:00:00