Cells persistently infected with newcastle disease virus: I. Properties of mutants isolated from persistently infected L cells.

abstract：:Interaction of the C-terminal domains of Sendai virus (SeV) P and N proteins is crucial for RNA synthesis by correctly positioning the polymerase complex (L+P) onto the nucleocapsid (N/RNA). To better understand this mechanism within the paramyxovirus family, we have studied the complex formed by the SeV C-terminal do...

journal_title：Journal of virology

authors： Houben K,Marion D,Tarbouriech N,Ruigrok RW,Blanchard L

更新日期：2007-07-01 00:00:00

abstract：:Nucleocapsid assembly in hepadnavirus replication requires selective encapsidation of the pregenomic RNA template and the viral polymerase by the core proteins. It has been shown that an encapsidation signal located at the 5' end of the pregenomic RNA is responsible for its interaction with the polymerase. In the pres...

journal_title：Journal of virology

authors： Howe AY,Tyrrell DL

更新日期：1996-08-01 00:00:00

abstract：:Here, we investigated the pre-steady-state deoxynucleoside triphosphate (dNTP) incorporation kinetics of primate foamy virus (PFV) reverse transcriptase (RT) in comparison with those of HIV-1 and MuLV RTs. PFV RT displayed a drastic reduction in primer extension at low dNTP concentrations where HIV-1 RT remains highly...

journal_title：Journal of virology

authors： Santos-Velazquez J,Kim B

更新日期：2008-08-01 00:00:00

abstract：:Myxomatosis is a recurrent problem on rabbit farms throughout Europe despite the success of vaccines. To identify gene variations of field and vaccine strains that may be responsible for changes in virulence, immunomodulation, and immunoprotection, the genomes of 6 myxoma virus (MYXV) strains were sequenced: German fi...

journal_title：Journal of virology

authors： Braun C,Thürmer A,Daniel R,Schultz AK,Bulla I,Schirrmeier H,Mayer D,Neubert A,Czerny CP

更新日期：2017-01-31 00:00:00

abstract：:African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal viral disease of domestic pigs that has significant economic consequences for the swine industry. The control of African swine fever (ASF) has been hampered by the unavailability of vaccines. Successful experimental vaccines hav...

journal_title：Journal of virology

authors： O'Donnell V,Risatti GR,Holinka LG,Krug PW,Carlson J,Velazquez-Salinas L,Azzinaro PA,Gladue DP,Borca MV

更新日期：2016-12-16 00:00:00

abstract：:We investigated the use of infectious cDNA for the production of poliovirus type 1-type 3 recombinants. One such recombinant virus was produced, but a second construct involving the transfer of part of the capsid protein region was not infectious. Our results suggest that the approach may prove valuable but that not a...

journal_title：Journal of virology

authors： Stanway G,Hughes PJ,Westrop GD,Evans DM,Dunn G,Minor PD,Schild GC,Almond JW

更新日期：1986-03-01 00:00:00

abstract：:To analyze proteolytic processing of foamy (spuma) retroviruses, two mutations were generated in the presumed active-site triplet Asp-Ser-Gly in the predicted proteinase (PR) region of the human foamy virus (HSRV). The mutations changed either the presumed catalytic aspartic acid residue to a catalytically incompetent...

journal_title：Journal of virology

authors： Konvalinka J,Löchelt M,Zentgraf H,Flügel RM,Kräusslich HG

更新日期：1995-11-01 00:00:00

abstract：:An immediate-early protein of murine cytomegalovirus (MCMV), pp89, elicits an immunodominant and protective major histocompatibility complex (MHC) class I Ld-restricted CD8+ T-lymphocyte response. Remarkably, presentation of the naturally processed peptide of pp89, the nonapeptide YPHFMPTNL, is abolished during permis...

journal_title：Journal of virology

authors： Hengel H,Lucin P,Jonjić S,Ruppert T,Koszinowski UH

更新日期：1994-01-01 00:00:00

abstract：:Nuclei of cells infected with Moloney murine leukemia virus (MoMuLV) were examined for the presence of gag proteins. This analysis was performed in conjunction with other studies suggesting a possible role for gag proteins in regulating nuclear events relating to processing and/or transport of viral genomic RNA. We de...

journal_title：Journal of virology

authors： Nash MA,Meyer MK,Decker GL,Arlinghaus RB

更新日期：1993-03-01 00:00:00

abstract：:The C-terminal domain of human immunodeficiency virus type 1 (HIV-1) integrase (IN) is a dimer that binds to DNA in a nonspecific manner. The structure of the minimal region required for DNA binding (IN220-270) has been solved by nuclear magnetic resonance spectroscopy. The overall fold of the C-terminal domain of HIV...

journal_title：Journal of virology

authors： Lutzke RA,Plasterk RH

更新日期：1998-06-01 00:00:00

abstract：:Six phages were isolated from sewage and from a lysogenic strain. Three of them, belonging to a new morphological group, had contractile tails and elongated heads with axial ratios of 2.4:1. Two phages, possessing short tails and very long heads with axial ratios of 3.5:1, were new isolates of an extremely rare group....

journal_title：Journal of virology

authors： Ackermann HW,Petrow S,Kasatiya SS

更新日期：1974-03-01 00:00:00

abstract：:To determine the extent and structure of genetic variation in dengue viruses (DENV) on a restricted spatial and temporal scale, we sequenced the E (envelope) genes of DENV-1, -2, and -3 isolates collected in 2001 from children enrolled in a prospective school-based study in Kamphaeng Phet, Thailand, and diagnosed with...

journal_title：Journal of virology

authors： Jarman RG,Holmes EC,Rodpradit P,Klungthong C,Gibbons RV,Nisalak A,Rothman AL,Libraty DH,Ennis FA,Mammen MP Jr,Endy TP

更新日期：2008-06-01 00:00:00

abstract：:A short sequence, located between the A14L and A15L open reading frames (ORFs) of vaccinia virus, was predicted to encode a hydrophobic protein of 53 amino acids that is conserved in orthopoxviruses, leporipoxviruses, yatapoxiruses, and molluscipoxviruses. We constructed a recombinant vaccinia virus with a 10-codon ep...

journal_title：Journal of virology

authors： Betakova T,Wolffe EJ,Moss B

更新日期：2000-05-01 00:00:00

abstract：:Two virus-specific species of newly synthesized DNA were isolated from rat fibroblast cell cultures infected with the Kilham rat virus (RV). These two DNA species were purified; their behavior on hydroxyapatite chromatography and their sedimentation coefficients in sucrose gradients were determined. One of the two spe...

journal_title：Journal of virology

authors： Gunther M,May P

更新日期：1976-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection causes not only intrahepatic diseases but also extrahepatic manifestations, including type 2 diabetes. We previously reported that HCV replication suppresses cellular glucose uptake by downregulation of cell surface expression of glucose transporter 2 (GLUT2) (D. Kasai et al., J. Hepa...

journal_title：Journal of virology

authors： Matsui C,Shoji I,Kaneda S,Sianipar IR,Deng L,Hotta H

更新日期：2012-12-01 00:00:00

abstract：:The VP24 protein plays an essential, albeit poorly understood role in the filovirus life cycle. VP24 is only 30% identical between Marburg virus and the ebolaviruses. Furthermore, VP24 from the ebolaviruses is immunosuppressive, while that of Marburg virus is not. The crystal structure of Marburg virus VP24, presented...

journal_title：Journal of virology

authors： Zhang AP,Bornholdt ZA,Abelson DM,Saphire EO

更新日期：2014-05-01 00:00:00

abstract：:We have previously described a nonconditional mutant of avian sarcoma virus (SE21Q1b) which fails to package viral RNA (Gallis et al., Virology 94:146-161, 1979; Linial et al., Cell 15:1371-1381, 1978). Quail cells transformed by SE21Q1b contain normal amounts of intracellular viral mRNA's for src, env, and gag-pol an...

journal_title：Journal of virology

authors： Shank PR,Linial M

更新日期：1980-11-01 00:00:00

abstract：:The large-particle fraction from the cytoplasm of chick embryo fibroblasts infected with Semliki Forest virus was found to catalyze the incorporation of the 5'-triphosphates of guanosine, adenine, cytidine, and uridine into an acid-insoluble alkali-labile product. The conditions affecting the preparation and assay of ...

journal_title：Journal of virology

authors： Martin EM,Sonnabend JA

更新日期：1967-02-01 00:00:00

abstract：:Recombinant Epstein-Barr viruses (EBVs) were made with mutated latent membrane protein 1 (LMP1) genes that express only the LMP1 amino-terminal cytoplasmic and six transmembrane domains (MS187) or these domains and the first 44 amino acids of the 200-residue LMP1 carboxy-terminal domain (MS231). After infection of pri...

journal_title：Journal of virology

authors： Kaye KM,Izumi KM,Mosialos G,Kieff E

更新日期：1995-02-01 00:00:00

abstract：:The double-stranded-DNA bacteriophages employ powerful molecular motors to translocate genomic DNA into preformed capsids during the packaging step in phage assembly. Bacillus subtilis bacteriophage 29 has an oligomeric prohead RNA (pRNA) that is an essential component of its packaging motor. The crystal structure of ...

journal_title：Journal of virology

authors： Zhao W,Saha M,Ke A,Morais MC,Jardine PJ,Grimes S

更新日期：2012-11-01 00:00:00

abstract：:An assay to identify interactions between Citrus Dwarfing Viroid (CDVd) and Citrus Tristeza Virus (CTV) showed that viroid titer was enhanced by the coinfecting CTV in Mexican lime but not in etrog citron. Since CTV encodes three RNA silencing suppressors (RSSs), p23, p20 and p25, an assay using transgenic Mexican lim...

journal_title：Journal of virology

authors： Serra P,Bani Hashemian SM,Fagoaga C,Romero J,Ruiz-Ruiz S,Gorris MT,Bertolini E,Duran-Vila N

更新日期：2014-01-01 00:00:00

abstract：:We previously reported that the expression of rotavirus phenotypes by reassortants was affected by recipient genetic background and proposed specific interactions between the outer capsid proteins VP4 and VP7 as the basis for the phenotypic effects (D. Chen, J. W. Burns, M. K. Estes, and R. F. Ramig, Proc. Natl. Acad....

journal_title：Journal of virology

authors： Chen DY,Estes MK,Ramig RF

更新日期：1992-01-01 00:00:00

abstract：:Acute arenavirus disease in primates, like Lassa hemorrhagic fever in humans, begins with flu-like symptoms and leads to death approximately 2 weeks after infection. Our goal was to identify molecular changes in blood that are related to disease progression. Rhesus macaques (Macaca mulatta) infected intravenously with...

journal_title：Journal of virology

authors： Djavani MM,Crasta OR,Zapata JC,Fei Z,Folkerts O,Sobral B,Swindells M,Bryant J,Davis H,Pauza CD,Lukashevich IS,Hammamieh R,Jett M,Salvato MS

更新日期：2007-08-01 00:00:00

abstract：:Viral infection induces production of type I interferons (IFNs), which stimulate the expression of a variety of antiviral factors to inhibit viral replication. To establish effective infection, viruses need to develop strategies to evade the immune responses. A neurovirulent Sindbis virus strain with neuroinvasive pro...

journal_title：Journal of virology

authors： Wang X,Li MMH,Zhao J,Li S,MacDonald MR,Rice CM,Gao X,Gao G

更新日期：2016-10-28 00:00:00

abstract：:A recombinant adenovirus was constructed by inserting the human immunodeficiency virus type 1 (HIV-1) envelope gene downstream from the early region 3 (E3) promoter of adenovirus type 5 (Ad5), replacing the coding sequences of E3. The recombinant virus replicated as efficiently as the parent virus in all cell lines te...

journal_title：Journal of virology

authors： Dewar RL,Natarajan V,Vasudevachari MB,Salzman NP

更新日期：1989-01-01 00:00:00

abstract：:Proteasomes are critical for the processing of antigens for presentation through the major histocompatibility complex (MHC) class I pathway. HIV-1 Gag protein is a component of several experimental HIV-1 vaccines. Therefore, understanding the processing of HIV-1 Gag protein and the resulting epitope repertoire is esse...

journal_title：Journal of virology

authors： Steers NJ,Currier JR,Kijak GH,di Targiani RC,Saxena A,Marovich MA,Kim JH,Michael NL,Alving CR,Rao M

更新日期：2011-02-01 00:00:00

abstract：:Infectious bursal disease virus (IBDV), a double-stranded RNA virus belonging to the Birnaviridae family, causes immunosuppression in chickens. In this study, we defined the localization of IBDV replication complexes based on colocalization analysis of VP3, the major protein component of IBDV ribonucleoproteins (RNPs)...

journal_title：Journal of virology

authors： Delgui LR,Rodríguez JF,Colombo MI

更新日期：2013-08-01 00:00:00

abstract：:Radioactive DNA complementary to nucleotide sequences in Moloney murine sarcoma virus (MSV) and Moloney leukemia virus (M-MuLV) complex was made by the endogenous reverse transcriptase reaction. These virus stocks contained a threefold excess of MSV over M-MuLV as measured by biological assay. The complementary DNA wa...

journal_title：Journal of virology

authors： Frankel AE,Neubauer RL,Fischinger PJ

更新日期：1976-05-01 00:00:00

abstract：:Genetic bottlenecks are important events in the genetic diversification of organisms and colonization of new ecological niches. Repeated bottlenecking of RNA viruses often leads to fitness losses due to the operation of Muller's ratchet. Herein we use vesicular stomatitis virus to determine the transmission population...

journal_title：Journal of virology

authors： Novella IS,Elena SF,Moya A,Domingo E,Holland JJ

更新日期：1995-05-01 00:00:00

abstract：:The DNA from Haemophilus influenzae temperate phage N3 was characterized by centrifugation and by electrophoresis after nuclease digestion. The double-stranded DNA, with a mass of 25.8 X 10(6) daltons, had single-strand cohesive ends. Strand association through cohesion was reduced by heat and removed by S1 nuclease d...

journal_title：Journal of virology

authors： Filipska ES,Moynet DJ,DeFilippes FM

更新日期：1981-10-01 00:00:00