Abstract:
:Ribosomes from ghost-treated Escherichia coli can form in vitro initiation complexes but cannot translate added template RNA because of a defect in the 30S subunit; 16S rRNA is degraded.
journal_name
J Viroljournal_title
Journal of virologyauthors
Simon M,Kennell Ddoi
10.1128/JVI.14.5.1310-1313.1974subject
Has Abstractpub_date
1974-11-01 00:00:00pages
1310-3issue
5eissn
0022-538Xissn
1098-5514journal_volume
14pub_type
杂志文章abstract::Cytolytic T-lymphocyte (CTL) activity specific for respiratory syncytial (RS) virus was investigated after intranasal infection of mice with RS virus, after intraperitoneal infection of mice with a recombinant vaccinia virus expressing the F glycoprotein, and after intramuscular vaccination of mice with Formalin-inact...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.64.9.4232-4241.1990
更新日期:1990-09-01 00:00:00
abstract::A selection strategy, the activator trap, was used in order to identify genes of human cytomegalovirus (HCMV) that encode strong transcriptional activation domains in mammalian cells. This approach is based on the isolation of activation domains from a GAL4 fusion library by means of selective plasmid replication, whi...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.76.10.4836-4847.2002
更新日期:2002-05-01 00:00:00
abstract::The pneumopathogenicity of a trypsin-sensitive revertant of Sendai virus, TSrev-58, which was derived from a trypsin-resistant mutant, TR-5, was examined in mice. In comparison with TR-5, the revertant had a single amino acid substitution at residue 116 (Ile----Arg) on F protein, which was the cleavage site, and had t...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.62.8.3040-3042.1988
更新日期:1988-08-01 00:00:00
abstract::The effect of herpes simplex virus type 2 (HSV-2) infection on the synthesis of DNA in human embryonic fibroblast cells was determined at temperatures permissive (37 C) and nonpermissive (42 C) for virus multiplication. During incubation of HSV-2 infected cultures at 42 C for 2 to 4 days or after shift-down from 42 to...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.15.3.534-539.1975
更新日期:1975-03-01 00:00:00
abstract::The bovine leukemia virus (BLV) is an oncogenic retrovirus that is associated with the development of persistent lymphocytosis (PL) and lymphoma in cattle. While B lymphocytes have been shown to be the primary cellular target of BLV, recent studies suggest that some T lymphocytes and monocytes may be infected by the v...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.70.4.2178-2183.1996
更新日期:1996-04-01 00:00:00
abstract::The polycistronic P/C mRNA of Sendai virus is translated under cell-free conditions into five proteins (P, C', C, Y1, and Y2) from overlapping reading frames. In this study, we showed that in addition to the P, C', and C proteins, Y1 and Y2 were expressed by six different Sendai virus strains in infected cells. The Y ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.63.2.974-977.1989
更新日期:1989-02-01 00:00:00
abstract::Infection of Escherichia coli with the satellite virus P4 without its helper bacteriophage P2 leads either to the immune integrated state or to the nonimmune multicopy plasmid condition. We analyzed the transcription pattern of the phage plasmid P4 early and late after infection and during the stable plasmid or lysoge...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.62.5.1697-1704.1988
更新日期:1988-05-01 00:00:00
abstract::Posttranslational modification-oligomerization, phosphorylation, and proteolytic cleavage-of the human papillomavirus (HPV) E4 protein occurs as the infected keratinocytes migrate up through the suprabasal wart layers. It has been postulated that these events modify E4 function during the virus life cycle. In HPV type...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.78.24.13920-13933.2004
更新日期:2004-12-01 00:00:00
abstract::Upon stimulation with alpha/beta interferon, rat cells synthesize three Mx proteins. Sequence analysis of corresponding cDNAs reveals that these three proteins are derived from three distinct genes. One of the rat cDNAs is termed Mx1 because it is most closely related to the mouse Mx1 cDNA and because it codes for a n...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.64.12.6263-6269.1990
更新日期:1990-12-01 00:00:00
abstract::As a subunit of both the P-L polymerase complex and the P-N assembly complex, the vesicular stomatitis virus (VSV) P protein plays a pivotal role in transcription and replication of the viral genome. Constitutive phosphorylation of this protein is currently thought to be essential for formation of the P-L complex. We ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.70.7.4538-4548.1996
更新日期:1996-07-01 00:00:00
abstract::The recognition of naturally occurring rhadinoviruses in macaque monkeys has spurred interest in their use as models for human infection with Kaposi sarcoma-associated herpesvirus (human herpesvirus 8). Rhesus macaques (Macaca mulatta) and pig-tailed macaques (Macaca nemestrina) were inoculated intravenously with rhad...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.73.12.10320-10328.1999
更新日期:1999-12-01 00:00:00
abstract::An immunological hierarchy among three H-2Db-restricted cytotoxic T lymphocyte (CTL) determinants in simian virus 40 (SV40) large T antigen (Tag) was described previously: determinants I and II/III are immunodominant, whereas determinant V is immunorecessive. To assess the immunogenicity of each determinant individual...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.72.2.1469-1481.1998
更新日期:1998-02-01 00:00:00
abstract::The interaction of the human immunodeficiency virus (HIV) Gag protein with the plasma membrane of a cell is a critical event in the assembly of HIV particles. The matrix protein region (MA) of HIV type 1 (HIV-1) Pr55Gag has previously been demonstrated to confer membrane-binding properties on the precursor polyprotein...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.71.9.6582-6592.1997
更新日期:1997-09-01 00:00:00
abstract::Four isolates of human papovaviruses (RF, GS, DW, and MG viruses) obtained from the urine specimens of renal allograft recipients in widely separated locations were compared with BK virus. Hemagglutination inhibition tests and plaque neutralization assays showed that all were antigenically related to BK virus. All iso...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.17.3.762-775.1976
更新日期:1976-03-01 00:00:00
abstract::We have isolated a new type of temperature-sensitive mutant of simian virus 40 (SV40) that is capable of productive infection in permissive cells but not of maintenance of viral DNA integration in transformed cells at the conditional temperature. Virus development is induced when cells transformed by this mutant are s...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.19.2.374-381.1976
更新日期:1976-08-01 00:00:00
abstract::To replicate its segmented, double-stranded RNA (dsRNA) genome, the rotavirus RNA-dependent RNA polymerase, VP1, must recognize viral plus-strand RNAs (+RNAs) and guide them into the catalytic center. VP1 binds to the conserved 3' end of rotavirus +RNAs via both sequence-dependent and sequence-independent contacts. Se...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01689-10
更新日期:2011-03-01 00:00:00
abstract::Human immunodeficiency virus type 2 (HIV-2), like other lentiviruses, is capable of infecting nondividing T cells and macrophages. The present work shows that in HIV-2-infected cells, Vpx is necessary for efficient nuclear import of the preintegration complex. In agreement with this finding, the subcellular localizati...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.74.13.6162-6167.2000
更新日期:2000-07-01 00:00:00
abstract::Reassortant viruses which possessed the hemagglutinin and neuraminidase genes of wild-type human influenza A viruses and the remaining six RNA segments (internal genes) of the avian A/Pintail/Alberta/119/79 (H4N6) virus were previously found to be attenuated in humans. To study the genetic basis of this attenuation, w...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.61.9.2857-2863.1987
更新日期:1987-09-01 00:00:00
abstract::The signaling lymphocyte activation molecule F1 (SLAMF1) is both a microbial sensor and entry receptor for measles virus (MeV). Herein, we describe a new role for SLAMF1 to mediate MeV endocytosis that is in contrast with the alternative, and generally accepted, model that MeV genome enters cells only after fusion at ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02255-16
更新日期:2017-03-13 00:00:00
abstract::The utility of the present generation of adenovirus (Ad) vectors for gene therapy applications could be improved by restricting native viral tropism to selected cell types. In order to achieve modification of Ad tropism, we proposed to exploit a minor component of viral capsid, protein IX (pIX), for genetic incorporat...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.76.14.6893-6899.2002
更新日期:2002-07-01 00:00:00
abstract::Walleye dermal sarcoma (WDS) and walleye epidermal hyperplasia (WEH) are skin diseases of walleye fish that appear and regress on a seasonal basis. We report here that the complex retroviruses etiologically associated with WDS (WDS virus [WDSV]) and WEH (WEH viruses 1 and 2 [WEHV1 and WEHV2, respectively]) encode D-ty...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.72.11.8765-8771.1998
更新日期:1998-11-01 00:00:00
abstract::Geminiviruses package circular single-stranded DNA and replicate in the nucleus via a double-stranded intermediate. This intermediate also serves as a template for bidirectional transcription by polymerase II. Here, we map promoters and transcripts and characterize regulatory proteins of Mungbean yellow mosaic virus-V...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.79.13.8149-8163.2005
更新日期:2005-07-01 00:00:00
abstract::The papillomavirus (PV) E2 protein is a critical regulator of viral transcription and genome replication. We previously reported that tyrosine (Y) 138 of HPV-31 E2 is phosphorylated by the fibroblast growth factor receptor 3 (FGFR3) kinase. In this study, we generated quasiviruses containing G418-selectable HPV-31 gen...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00488-20
更新日期:2020-07-01 00:00:00
abstract::Rabies virus nucleoprotein (N) plays vital roles in regulation of viral RNA transcription and replication by encapsidation of the nascent genomic RNA. Rabies virus N is phosphorylated, and previous studies demonstrated that mutation of the phosphorylated serine at position 389 to alanine resulted in reduction of viral...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.76.9.4153-4161.2002
更新日期:2002-05-01 00:00:00
abstract::Despite intensive research on the identification of T-cell epitopes in cattle after foot-and-mouth disease virus (FMDV) infection during the last 20 years, knowledge of major histocompatibility complex (MHC) restriction and anchor residues of such epitopes is still sparse. Therefore, as a first step, we tested lymphoc...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01534-08
更新日期:2009-05-01 00:00:00
abstract::We describe initial genetic and structural characterizations of HK97, a temperate bacteriophage of Escherichia coli. We isolated 28 amber mutants, characterized them with respect to what phage-related structures they make, and mapped many of them to restriction fragments of genomic DNA. Sodium dodecyl sulfate-polyacry...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.65.6.3227-3237.1991
更新日期:1991-06-01 00:00:00
abstract::The initial host response to viral infection occurs after Toll-like receptors (TLRs) on dendritic cells (DC) are stimulated by viral nucleic acids (double-stranded RNA, single-stranded RNA) and alpha interferon (IFN-alpha) and IFN-beta are produced. We hypothesized that pharmacologic induction of innate antiviral resp...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.79.22.14355-14370.2005
更新日期:2005-11-01 00:00:00
abstract::In earlier studies, we have shown that superinfection of an interleukin-2 (IL-2)-dependent, Moloney murine leukemia virus (MoMuLV)-induced rat T-cell lymphoma line (4437A) with mink cell focus-forming (also called polytropic) murine retroviruses induces rapid progression to IL-2-independent growth. In this report, we ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.68.12.7709-7716.1994
更新日期:1994-12-01 00:00:00
abstract::The phenotypic properties of ICP27 temperature-sensitive and deletion mutants and the results of transient expression assays have demonstrated that ICP27 has a modulatory effect on viral gene expression induced by ICPs 0 and 4. In order to identify the regions of the ICP27 molecule that are responsible for its enhanci...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.64.7.3471-3485.1990
更新日期:1990-07-01 00:00:00
abstract::Two panels of monoclonal antibodies (MAbs) specific for the influenza A virus PA and PB2 polypeptides have been obtained from mice immunized with denatured proteins produced in Escherichia coli. All MAbs (13 specific for the PA polypeptide and 8 specific for the PB2 protein) reacted to the corresponding influenza viru...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.68.11.6900-6909.1994
更新日期:1994-11-01 00:00:00