Induction of secreted human immunodeficiency virus type 1 (HIV-1) resistance factors in CD4-positive T lymphocytes by attenuated HIV-1 infection.

abstract：:When electrophoresed in 0.7% agarose gels, populations of reovirus particles can be resolved into 13 well-defined bands that possess from 0 to 12 projection/spike-associated trimers of protein sigma 1. This state of affairs is not an artifact of purification, of the techniques used to demonstrate it, of aggregation, o...

journal_title：Virology

authors： Larson SM,Antczak JB,Joklik WK

更新日期：1994-06-01 00:00:00

abstract：:A series of CD8(+) T cell clones, specific for the IE1 epitope YPHFMPTNL, of the immediate-early protein 1 of the murine cytomegalovirus (MCMV) were generated in order to determine their protective activity against this infection and correlate their phenotypic markers with antiviral activity. We found that the adoptiv...

journal_title：Virology

authors： Fernandez JA,Zavala F,Tsuji M

更新日期：1999-03-01 00:00:00

abstract：:The reticuloendotheliosis virus (REV) group of retroviruses and type D simian retroviruses (SRV) belong to the same receptor interference group. The cellular receptor for these viruses has not yet been identified. In order to study the distribution of the receptor and to identify a receptor negative cell line, vector ...

journal_title：Virology

authors： Koo HM,Parthasarathi S,Ron Y,Dougherty JP

更新日期：1994-11-15 00:00:00

abstract：:Cucumber seedlings infected with cucumber mosaic virus (CMV) contain a virus-induced RNA-dependent RNA polymerase (RNA replicase) in both soluble and particulate fractions of plant extracts; no such activity is found in uninfected plants. The extensive purification and characterization of the soluble RNA replicase has...

journal_title：Virology

authors： Gill DS,Kumarasamy R,Symons RH

更新日期：1981-08-01 00:00:00

abstract：:To determine if West Nile virus (WNV) infection of insect cells induces a protective RNAi response, Drosophila melanogaster S2 and Aedes albopictus C6/36 cells were infected with WNV, and the production of WNV-homologous small RNAs was assayed as an indicator of RNAi induction. A distinct population of approximately 2...

journal_title：Virology

authors： Chotkowski HL,Ciota AT,Jia Y,Puig-Basagoiti F,Kramer LD,Shi PY,Glaser RL

更新日期：2008-07-20 00:00:00

abstract：:Murine monoclonal antibodies were developed against the protein products produced by murine C127 cells which had been transfected with a recombinant plasmid clone containing the human T-cell leukemia (lymphotropic) virus type I (HTLV-I) proviral DNA coding regions for part of env, px, and the 3' LTR. Four antibodies w...

journal_title：Virology

authors： Newman MJ,Baker IT,Reitz MS,Eiden M,Blattner WA,Gallo RC,Mann DL

更新日期：1986-04-15 00:00:00

abstract：:Currently, little is known about the ankyrin/F-box protein B4. Here, we report that B4R-null viruses exhibited reduced plaque size in tissue culture, and decreased ability to spread, as assessed by multiple-step growth analysis. Electron microscopy indicated that B4R-null viruses still formed mature and extracellular ...

journal_title：Virology

authors： Burles K,Irwin CR,Burton RL,Schriewer J,Evans DH,Buller RM,Barry M

更新日期：2014-05-01 00:00:00

abstract：:Human rotaviruses (Wa, KUN, MO) showed hemagglutination (HA) only with fixed 1-day-old chicken erythrocytes, and their HA activities were completely destroyed by trypsin activation of virions. Simian SA-11 and bovine NCDV had HA activities not only against fixed erythrocytes but also against fresh erythrocytes from va...

journal_title：Virology

authors： Fukudome K,Yoshie O,Konno T

更新日期：1989-09-01 00:00:00

abstract：:Red clover necrotic mosaic virus (RCNMV) encodes N-terminally overlapping proteins of 27 and 88 kDa (p27 and p88) known to be required for replication. Green fluorescent protein (GFP) fusions were used to visualize the location of p27 and p88 within Nicotiana benthamiana cells. GFP:p27 fusions localized to the endopla...

journal_title：Virology

authors： Turner KA,Sit TL,Callaway AS,Allen NS,Lommel SA

更新日期：2004-03-15 00:00:00

abstract：:HPV16 E6 deregulates G1/S cell cycle progression through p53 degradation preventing transcription of the CDK inhibitor p21(WAF1). However, additional mechanisms independent of p53 inactivation appear to exist. Here, we report that HPV16 E6 targets the cellular factor p150(Sal2), which positively regulates p21(WAF1) tr...

journal_title：Virology

authors： Parroche P,Touka M,Mansour M,Bouvard V,Thépot A,Accardi R,Carreira C,Roblot GG,Sylla BS,Hasan U,Tommasino M

更新日期：2011-09-01 00:00:00

abstract：:Cytotoxic T-cell clones raised against X-31 (H3N2) influenza virus in C57BL/6 mice can be directed against an influenza A virus subtype specific determinant (1). A representative T-cell clone (A3.1) has been used in combination with a set of genetically typed recombinant viruses, to show that the A/PR/8/34 nucleoprote...

journal_title：Virology

authors： Townsend AR,Skehel JJ,Taylor PM,Palese P

更新日期：1984-03-01 00:00:00

abstract：:To define the number of rhinovirus serotypes, cross neutralization tests and characterization studies were completed on 25 candidate prototype rhinoviruses submitted to a third phase of a collaborative program. Based on the results, 11 distinct prototype strains were designated and the numbering system was extended to...

journal_title：Virology

authors： Hamparian VV,Colonno RJ,Cooney MK,Dick EC,Gwaltney JM Jr,Hughes JH,Jordan WS Jr,Kapikian AZ,Mogabgab WJ,Monto A

更新日期：1987-07-01 00:00:00

abstract：:Ribavirin is the first synthetic, broad-spectrum antiviral nucleoside. Despite its more than 30 year history, the mechanism of action of this compound remains unclear and somewhat controversial. Recent data suggest the possibility that the activity of ribavirin against RNA viruses is a reflection of incorporation of r...

journal_title：Virology

authors： Graci JD,Cameron CE

更新日期：2002-07-05 00:00:00

abstract：:Many tumors, including cervical carcinoma, show dysregulated expression of the microRNA processing machinery, specifically DROSHA and DICER. Some cervical cancers exhibit chromosome 5p amplifications and DROSHA is the most significantly upregulated transcript and is observed in all tumors with 5p gain. DROSHA and DICE...

journal_title：Virology

authors： Harden ME,Munger K

更新日期：2017-07-01 00:00:00

abstract：:Dipeptidyl peptidase 4 (DPP4) is a receptor for MERS-CoV. The soluble form of DPP4 (sDPP4) circulates systematically and can competitively inhibit MERS-CoV entry into host cells. Here, we measured the concentration of sDPP4 in the plasma and sputa of 14 MERS-CoV-infected patients of various degrees of disease severity...

journal_title：Virology

authors： Inn KS,Kim Y,Aigerim A,Park U,Hwang ES,Choi MS,Kim YS,Cho NH

更新日期：2018-05-01 00:00:00

abstract：:Altered cytokine profiles and imbalanced frequencies of CD4(+) T helper cell subsets are thought to be linked with HIV-1/AIDS pathogenesis, but the causes need to be further clarified. Histamine, a biogenic amine with many functions, shows enhancement in HIV-1 infected individuals, which are considered to link with di...

journal_title：Virology

authors： Zhai RR,Jiang AP,Wang HB,Ma L,Ren XX,Jiang JF,Wu L,Wei JF,Wang JH

更新日期：2013-08-01 00:00:00

abstract：:Several sulfated polysaccharides (dextran sulfate, pentosan polysulfate, heparin) and copolymers of acrylic acid with vinylalcohol sulfate have proved to be potent inhibitors of human cytomegalovirus (CMV) infectivity in vitro. Sulfated alpha-cyclodextrins are only weak inhibitors of CMV. A close correlation was found...

journal_title：Virology

authors： Neyts J,Snoeck R,Schols D,Balzarini J,Esko JD,Van Schepdael A,De Clercq E

更新日期：1992-07-01 00:00:00

abstract：:Unusual Plum pox virus (PPV) isolates (named Tat isolates) were discovered on sour cherry (Prunus cerasus) in Russia. They failed to be recognized by RT-PCR using commonly employed primers specific to the strains C or CR (the only ones that proved able to infect sour cherry) as well as to the strains M and W. Some of ...

journal_title：Virology

authors： Chirkov S,Ivanov P,Sheveleva A,Zakubanskiy A,Osipov G

更新日期：2017-02-01 00:00:00

abstract：:While trying to generate a site-directed deletion in the ORF63 latency-associated gene of varicella-zoster virus (VZV) Oka, we constructed a virus with an unexpected rearrangement. The virus has a small deletion in both copies of ORF63 and two copies of a cassette inserted between ORFs 64/65 and 68/69 containing (a) t...

journal_title：Virology

authors： Ambagala AP,Krogmann T,Qin J,Pesnicak L,Cohen JI

更新日期：2010-04-10 00:00:00

abstract：:The measles virus RNA-dependent RNA polymerase consists of two virus-encoded subunits, the phosphoprotein (P) and the large (L) protein. The P mRNA also codes for a C protein in the +1 reading frame relative to P. The activities of the measles P and C proteins from the vaccine strain, EdB, a wild-type CM strain, and a...

journal_title：Virology

authors： Reutter GL,Cortese-Grogan C,Wilson J,Moyer SA

更新日期：2001-06-20 00:00:00

abstract：:The measles virus (MV) phosphoprotein (P) and V proteins block the interferon (IFN) response by impeding phosphorylation of the signal transducer and activator of transcription 1 (STAT1) by the Janus kinase 1 (JAK1). We characterized how STAT1 mutants interact with P and JAK1 phosphorylation. Certain mutants of the li...

journal_title：Virology

authors： Devaux P,Priniski L,Cattaneo R

更新日期：2013-09-01 00:00:00

abstract：:Gammaherpesviruses establish life-long infection in most adults and are associated with the development of B cell lymphomas. While the interaction between gammaherpesviruses and splenic B cells has been explored, very little is known about gammaherpesvirus infection of B-1 B cells, innate-like B cells that primarily r...

journal_title：Virology

authors： Rekow MM,Darrah EJ,Mboko WP,Lange PT,Tarakanova VL

更新日期：2016-05-01 00:00:00

abstract：:Cells infected with a reassortant (113/Ho, H7N2) between A/fowl plague/Rostock/34 (FPV, H7N1) and A/Hong Kong/1/68 (H3N2) carrying RNA segments 1 and 6 of the Hong Kong virus and the residual genes of FPV, synthesized at 40 degrees a neuraminidase (NA) which is enzymatically not active and which is not incorporated in...

journal_title：Virology

authors： Breuning A,Scholtissek C

更新日期：1986-04-15 00:00:00

abstract：:Tissues from Australian brushtail possums (Trichosurus vulpecula) that had been experimentally infected with wobbly possum disease (WPD) virus (WPDV) were examined to elucidate pathogenesis of WPDV infection. Mononuclear inflammatory cell infiltrates were present in livers, kidneys, salivary glands and brains of WPD-a...

journal_title：Virology

authors： Giles J,Perrott M,Roe W,Shrestha K,Aberdein D,Morel P,Dunowska M

更新日期：2018-09-01 00:00:00

abstract：:The most recent introduction of an avian influenza A virus without reassortment into mammals occurred in 1979 when H1N1 strains could be isolated from diseased pigs in northern Europe. This newly introduced avian virus formed a stable lineage in pigs and, in the meantime, spread all over Europe. In 1991 highly pathoge...

journal_title：Virology

authors： Ludwig S,Haustein A,Kaleta EF,Scholtissek C

更新日期：1994-07-01 00:00:00

abstract：:Defective interfering particles of New Jersey serotype VSV were found to contain very little or no virion transcriptase activity. Furthermore no VSV transcriptase activity was observed in cells treated with cycloheximide and infected with DI. Cells infected with DI together with standard infectious virus and cyclohexi...

journal_title：Virology

authors： Perrault J,Holland JJ

更新日期：1972-10-01 00:00:00

abstract：:Sulfolobus turreted icosahedral virus (STIV) infects Sulfolobus species found in the hot springs of Yellowstone National Park. Its 37 open reading frames (ORFs) generally lack sequence similarity to other genes. One exception, however, is ORF B116. While its function is unknown, orthologs are found in three additional...

journal_title：Virology

authors： Larson ET,Eilers BJ,Reiter D,Ortmann AC,Young MJ,Lawrence CM

更新日期：2007-07-05 00:00:00

abstract：:Red sea bream iridovirus (RSIV) of the Iridoviridae family is a causative agent of lethal infections in many cultured marine fish species in southwestern Japan. RSIV-induced apoptosis was divided as follows: (1). cell shrinkage and rounding at the early apoptotic stage, (2). cell enlargement at the middle apoptotic st...

journal_title：Virology

authors： Imajoh M,Sugiura H,Oshima S

更新日期：2004-05-01 00:00:00

abstract：:A combination of linker scanning mutagenesis and deletional analyses has been used to determine the role of individual DNA-protein binding sites on expression from the hepatitis B virus (HBV) enhancer I-X promoter (map position (mp) 1042-1354, HBV adw2). Linker scanning mutation of the EF-C site caused a 67.5% drop in...

journal_title：Virology

authors： Gustin K,Shapiro M,Lee W,Burk RD

更新日期：1993-04-01 00:00:00

abstract：:Poliovirus was first isolated nearly 100 years ago in a landmark experiment that established the viral etiology of poliomyelitis. This discovery stimulated investigation of the pathogenesis of poliomyelitis in many laboratories. Nearly 50 years later, when two effective poliovirus vaccines were developed, the impetus ...

journal_title：Virology

authors： Racaniello VR

更新日期：2006-01-05 00:00:00