Wingless signaling induces nautilus expression in the ventral mesoderm of the Drosophila embryo.

abstract：:To examine the conditions of cell composition necessary for formation of a complete tadpole, defect embryos of 35 series were prepared by removing particular cells from 16- and 32-cell embryos of Xenopus laevis. These defect embryos were cultured and their development was examined. Formation of a complete tadpole did ...

journal_title：Developmental biology

authors： Kageura H

更新日期：1995-08-01 00:00:00

abstract：:These studies were designed to test the hypothesis that sperm nuclear decondensation and male pronuclear formation during hamster fertilization depend upon the ability of the fertilized oocyte to reduce sperm nuclear disulfide bonds. In a first series of experiments, treatment of mature oocytes with the sulfhydryl blo...

journal_title：Developmental biology

authors： Perreault SD,Wolff RA,Zirkin BR

更新日期：1984-01-01 00:00:00

abstract：:It has long been hypothesized that in fishes the contents of cortical granules are involved in the hardening of egg envelope following fertilization. We previously purified the egg envelope hardening initiation factor from the exudates released from activated medaka (Oryzias latipes) eggs and tentatively termed this p...

journal_title：Developmental biology

authors： Shibata Y,Iwamatsu T,Suzuki N,Young G,Naruse K,Nagahama Y,Yoshikuni M

更新日期：2012-12-15 00:00:00

abstract：:Cell adhesion molecules (CAMs) perform numerous functions during neural development. An individual CAM can play different roles during each stage of neuronal differentiation; however, little is known about how such functional switching is accomplished. Here we show that Drosophila N-cadherin (CadN) is required at mult...

journal_title：Developmental biology

authors： Kurusu M,Katsuki T,Zinn K,Suzuki E

更新日期：2012-06-15 00:00:00

abstract：:During meiotic maturation or after fertilization of invertebrate and vertebrate oocytes, many of the quiescent stored mRNAs are recruited into polysomes. In the clam, Spisula solidissima, such masked messages include the abundant mRNAs encoding cyclin A and the small subunit of ribonucleotide reductase. We have previo...

journal_title：Developmental biology

authors： Walker J,Dale M,Standart N

更新日期：1996-01-10 00:00:00

abstract：:Early spermatids contain roughly 1000-fold more TATA-binding protein (TBP) mRNA than do somatic cells. The appearance of TBP-overexpressing spermatids in the developing testis is accompanied by a large increase in whole-organ levels of total RNA and of poly(A)+ RNA per cell. Whereas somatic cells initiate transcriptio...

journal_title：Developmental biology

authors： Schmidt EE,Schibler U

更新日期：1997-04-01 00:00:00

abstract：:The vertebrate eye anlage grows out of the brain and folds into bilayered optic cups. The eye is patterned along multiple axes, precisely controlled by genetic programs, to delineate neural retina, pigment epithelium, and optic stalk tissues. Pax genes encode developmental regulators of key morphogenetic events, with ...

journal_title：Developmental biology

authors： Bosze B,Suarez-Navarro J,Soofi A,Lauderdale JD,Dressler GR,Brown NL

更新日期：2021-01-09 00:00:00

abstract：:Developmental boundaries ensure that cells fated to participate in a particular structure are brought together or maintained at the appropriate locale within developing embryos. Parasegment grooves mark the position of boundaries that separate every segment of the Drosophila embryo into anterior and posterior compartm...

journal_title：Developmental biology

authors： Larsen C,Bardet PL,Vincent JP,Alexandre C

更新日期：2008-09-15 00:00:00

abstract：:Myogenesis in the embryo and the adult mammal consists of a highly organized and regulated sequence of cellular processes to form or repair muscle tissue that include cell proliferation, migration, and differentiation. Data from cell culture and in vivo experiments implicate both FGFs and HGF as critical regulators of...

journal_title：Developmental biology

authors： Cornelison DD,Filla MS,Stanley HM,Rapraeger AC,Olwin BB

更新日期：2001-11-01 00:00:00

abstract：:Caudal homeobox genes are found across animals, typically linked to two other homeobox genes in what has been called the ParaHox cluster. These genes have been proposed to pattern the anterior-posterior axis of the endoderm ancestrally, but the expression of Caudal in extant groups is varied and often occurs in other ...

journal_title：Developmental biology

authors： Johnson AB,Lambert JD

更新日期：2021-02-01 00:00:00

abstract：:Trichosia pubescens larvae were ligated at different prepupal developmental stages in order to investigate whether ecdysterone acts just as a trigger or whether its presence in the hemolymph is constantly necessary for the induction of the late puffs, in particular the DNA puffs. The larvae were ligated in the middle ...

journal_title：Developmental biology

authors： Amabis DC,Amabis JM

更新日期：1984-03-01 00:00:00

abstract：:Metaphase II arrest of Xenopus oocyte is characterized by the presence of M-phase-promoting factor (MPF) and of a microtubular spindle, both of which are stable in the presence of protein synthesis inhibitors. We studied in vivo this equilibrium state that is settled during meiotic maturation. At time of germinal vesi...

journal_title：Developmental biology

authors： Thibier C,De Smedt V,Poulhe R,Huchon D,Jessus C,Ozon R

更新日期：1997-05-01 00:00:00

abstract：:In medusae of the hydrozoan Cytaeis uchidae, oocyte meiotic maturation and spawning occur as a consequence of dark-light transition. In this study, we investigated the mechanism underlying the initiation of meiotic maturation using in vitro (isolated oocytes from ovaries) and in vivo (ovarian oocytes in medusae) syste...

journal_title：Developmental biology

authors： Takeda N,Kyozuka K,Deguchi R

更新日期：2006-10-01 00:00:00

abstract：:The gastrointestinal (GI) tract of metazoans is lined by a series of regionally distinct epithelia. To maintain structure and function of the GI tract, regionally diversified differentiation of somatic stem cell (SC) lineages is critical. The adult Drosophila midgut provides an accessible model to study SC regulation ...

journal_title：Developmental biology

authors： Li H,Qi Y,Jasper H

更新日期：2016-11-15 00:00:00

abstract：:The polypeptide sequence predicted from the Pem oncofetal gene cDNA contains a homeodomain most closely related to the paired class. Pem, paired class member orthodenticle, and the bicoid maternal gene product homeodomains all have lysine residues at a recognition helix position implicated in DNA-binding specificity. ...

journal_title：Developmental biology

authors： Rayle RE

更新日期：1991-07-01 00:00:00

abstract：:Neural crest cells migrate along two pathways in the trunk: the ventral path, between the neural tube and somite, and the dorsolateral path, between the somite and overlying ectoderm. In avian embryos, ventral migration precedes dorsolateral migration by nearly 24 h, and the onset of dorsolateral migration coincides w...

journal_title：Developmental biology

authors： Reedy MV,Faraco CD,Erickson CA

更新日期：1998-08-15 00:00:00

abstract：:We report here the identification and characterization of a novel gene, T1 alpha, expressed in high abundance in adult rat lung, fetal lung, and early fetal brain. T1 alpha was identified by a monoclonal antibody previously shown to be specific for an antigen expressed by alveolar epithelial type I cells. The cDNA for...

journal_title：Developmental biology

authors： Rishi AK,Joyce-Brady M,Fisher J,Dobbs LG,Floros J,VanderSpek J,Brody JS,Williams MC

更新日期：1995-01-01 00:00:00

abstract：:XX gonads differentiate into ovaries, a morphologic event evident by embryonic day 13.5 (E13.5) in mice. To identify early markers of oogenesis, sex-specific urogenital ridge cDNA libraries were constructed from E12-13 embryos. After mass excision and isolation of plasmid DNA, approximately 4800 expressed sequence tag...

journal_title：Developmental biology

authors： Takasaki N,McIsaac R,Dean J

更新日期：2000-07-01 00:00:00

abstract：:In this paper we present a structural and functional characterization of a new sea urchin embryo transcription factor, SpRunt-1. This factor was isolated by means of its specific interaction with a cis-regulatory target site of the CyIIIa gene. Here we show that this target site, the P7I site, is required for normal e...

journal_title：Developmental biology

authors： Coffman JA,Kirchhamer CV,Harrington MG,Davidson EH

更新日期：1996-02-25 00:00:00

abstract：:Joint and skeletal development is highly regulated by extracellular matrix (ECM) proteoglycans, of which chondroitin sulfate proteoglycans (CSPGs) are a major class. Despite the requirement of joint CSPGs for skeletal flexibility and structure, relatively little is understood regarding their role in establishing joint...

journal_title：Developmental biology

authors： Wilson DG,Phamluong K,Lin WY,Barck K,Carano RA,Diehl L,Peterson AS,Martin F,Solloway MJ

更新日期：2012-03-15 00:00:00

abstract：:The Wnt pathways are evolutionarily well-conserved signal transduction pathways that are known to play important roles in all Metazoans investigated to date. Here, we examine the Wnt pathway genes and target genes present in the genome of the echinoderm Strongylocentrotus purpuratus. Analysis of the Wnt genes revealed...

journal_title：Developmental biology

authors： Croce JC,Wu SY,Byrum C,Xu R,Duloquin L,Wikramanayake AH,Gache C,McClay DR

更新日期：2006-12-01 00:00:00

abstract：:Developing vertebrate limbs are often utilized as a model for studying pattern formation and morphogenetic cell death. Herein, we report that conditional deletion of Rac1, a member of the Rho family of proteins, in mouse limb bud mesenchyme led to skeletal deformities in the autopod and soft tissue syndactyly, with th...

journal_title：Developmental biology

authors： Suzuki D,Yamada A,Amano T,Yasuhara R,Kimura A,Sakahara M,Tsumaki N,Takeda S,Tamura M,Nakamura M,Wada N,Nohno T,Shiroishi T,Aiba A,Kamijo R

更新日期：2009-11-15 00:00:00

abstract：:Major insulin gene transcription factors, such as PDX-1 or NeuroD1, have equally important roles in pancreatic development and the differentiation of pancreatic endocrine cells. Previously, we identified and cloned another critical insulin gene transcription factor MafA (RIPE3b1) and reported that other Maf factors we...

journal_title：Developmental biology

authors： Nishimura W,Kondo T,Salameh T,El Khattabi I,Dodge R,Bonner-Weir S,Sharma A

更新日期：2006-05-15 00:00:00

abstract：:We describe mesendoderm morphogenesis during gastrulation in the frog Xenopus laevis and investigate the mechanics of these movements with tissue explants. When a dorsal marginal zone explant is plated onto fibronectin, the mesendoderm moves away from the dorsal axial tissues as an intact sheet. Mesendodermal cells wi...

journal_title：Developmental biology

authors： Davidson LA,Hoffstrom BG,Keller R,DeSimone DW

更新日期：2002-02-15 00:00:00

abstract：:Coordinated locomotion of Drosophila larvae depends on accurate patterning and stable attachment to the cuticle of both muscles and proprioceptors (chordotonal organs). Unlike muscle spindles in mammals, the fly chordotonal organs are not embedded in the body-wall muscles. Yet, the contractile system (muscles and tend...

journal_title：Developmental biology

authors： Klein Y,Halachmi N,Egoz-Matia N,Toder M,Salzberg A

更新日期：2010-01-15 00:00:00

abstract：:In the spawned Xenopus egg, germ plasm is found as cytoplasmic islands spread over a wide cortical region of the vegetal pole. However, by the blastula stage, the same material is found concentrated into a few large blastomeres at the floor of the blastocoel. Components of the germ plasm can be specifically labeled wi...

journal_title：Developmental biology

authors： Savage RM,Danilchik MV

更新日期：1993-06-01 00:00:00

abstract：:Growth factors and the extracellular matrix have been shown to fulfill vital developmental roles in many embryonic systems. Our hypothesis is that a developmental role played by the extracellular matrix in sea urchins may be the binding of a PDGF-like growth factor to promote signaling activity. We report here that an...

journal_title：Developmental biology

authors： Govindarajan V,Ramachandran RK,George JM,Shakes DC,Tomlinson CR

更新日期：1995-12-01 00:00:00

abstract：:Effective transgenesis methods have been successfully employed in many organisms including zebrafish. However, accurate spatiotemporal control of transgene expression is still difficult to achieve. Here we describe a system for chemical-inducible gene expression and demonstrate its feasibility for generating transgeni...

journal_title：Developmental biology

authors： Emelyanov A,Parinov S

更新日期：2008-08-01 00:00:00

abstract：:The enteric nervous system (ENS) forms from the neural crest-derived precursors that colonize the bowel before differentiating into a network of neurons and glia that control intestinal function. Retinoids are essential for normal ENS development, but the role of retinoic acid (RA) metabolism in development remains in...

journal_title：Developmental biology

authors： Wright-Jin EC,Grider JR,Duester G,Heuckeroth RO

更新日期：2013-09-01 00:00:00

abstract：:P19 embryonal carcinoma cells are multipotential stem cells that differentiate into striated muscle as well as some other cell types when aggregated and exposed to dimethyl sulfoxide (DMSO). Immunofluorescence experiments using monospecific antibodies indicated that the majority of muscle cells were mononucleate and c...

journal_title：Developmental biology

authors： Rudnicki MA,Jackowski G,Saggin L,McBurney MW

更新日期：1990-04-01 00:00:00