Dynamics of germ plasm localization and its inhibition by ultraviolet irradiation in early cleavage Xenopus embryos.

abstract：:Morphogenesis of the cartilaginous otic capsule is directed by interactions between the epithelial anlage of the membranous labyrinth (otocyst) and its associated periotic mesenchyme. Utilizing a developmental series of high-density (micromass) cultures of periotic mesenchyme to model capsule chondrogenesis, we have s...

journal_title：Developmental biology

authors： Frenz DA,Van De Water TR

更新日期：1991-03-01 00:00:00

abstract：:Three dominant second-chromosome rearrangement mutations in Drosophila melanogaster, Aristapedioid1 (Arp), vestigial-Depilate (vgD), and vestigial62 (vg62), result in developmental abnormalities of the bristle sense organs on the notum, abdomen, legs, and wing margin. The bristle abnormalities are associated with over...

journal_title：Developmental biology

authors： Sharp EJ,Martin EC,Adler PN

更新日期：1994-02-01 00:00:00

abstract：:Proper spatial expression of the wingless (wg) gene in the Drosophila embryonic epidermis is crucial to intrasegmental patterning. Single cell wide wg expression is initiated at the blastoderm stage in response to combinatorial regulation by the pair rule genes. Later, during gastrulation, when the epidermal expressio...

journal_title：Developmental biology

authors： Yoffe KB,Manoukian AS,Wilder EL,Brand AH,Perrimon N

更新日期：1995-08-01 00:00:00

abstract：:Concentration of mast-cell precursors in hematopoietic tissues of mouse embryos was evaluated by a limiting dilution method. Cells from yolk sacs, livers, and bodies of (WB x C57BL/6)F1 (hereafter called WBB6F1)- +/+ embryos were injected directly into the skin of adult WBB6F1-W/Wv mice which were genetically depleted...

journal_title：Developmental biology

authors： Sonoda T,Hayashi C,Kitamura Y

更新日期：1983-05-01 00:00:00

abstract：:Three different null alleles of the myogenic bHLH gene MRF4/herculin/Myf-6 were created recently. The three alleles were similar in design but were surprisingly different in the intensity of their phenotypes, which ranged from complete viability of homozygotes to complete lethality. One possible explanation for these ...

journal_title：Developmental biology

authors： Yoon JK,Olson EN,Arnold HH,Wold BJ

更新日期：1997-08-15 00:00:00

abstract：:In this study, we demonstrate the developmental activation, in the zebrafish embryo, of a surveillance mechanism which triggers apoptosis to remove damaged cells. We determine the time course of activation of this mechanism by exposing embryos to camptothecin, an agent which specifically inhibits topoisomerase I withi...

journal_title：Developmental biology

authors： Ikegami R,Hunter P,Yager TD

更新日期：1999-05-15 00:00:00

abstract：:Chick sensory neurons grow to their correct targets in the hindlimb from the outset during normal development and following various experimental manipulations. This may result not because sensory neurons respond to specific limb-derived cues, but because they interact in some way with motoneurons which are responsive ...

journal_title：Developmental biology

authors： Landmesser L,Honig MG

更新日期：1986-12-01 00:00:00

abstract：:During development of the central nervous system (CNS), commissural axons grow toward the ventral midline. After crossing the floor plate, they abruptly change their trajectory from the circumferential to the longitudinal axis. The contacts between the commissural axons and the floor plate cells are involved in this a...

journal_title：Developmental biology

authors： Okabe N,Shimizu K,Ozaki-Kuroda K,Nakanishi H,Morimoto K,Takeuchi M,Katsumaru H,Murakami F,Takai Y

更新日期：2004-09-15 00:00:00

abstract：:We examined the effects of ciliary neurotrophic factor (CNTF) and depolarization, two environmental signals that influence noradrenergic and cholinergic function, on neuropeptide expression by cultured sympathetic neurons. Sciatic nerve extract, a rich source of CNTF, increased levels of vasoactive intestinal peptide ...

journal_title：Developmental biology

authors： Rao MS,Tyrrell S,Landis SC,Patterson PH

更新日期：1992-04-01 00:00:00

abstract：:The Ca2+ oscillations initiated by the fertilizing sperm (but terminating concomitant with pronucleus formation) apparently ensure that the events constituting egg activation occur in the correct temporal order; early events (e.g., cortical granule exocytosis) require fewer oscillations than later events (e.g., recrui...

journal_title：Developmental biology

authors： Ozil JP,Banrezes B,Tóth S,Pan H,Schultz RM

更新日期：2006-12-15 00:00:00

abstract：:We investigated whether the inhibition of proteoglycan synthesis and salivary branching morphogenesis by beta-D-xyloside was related to the deposition and processing of newly synthesized glycosaminoglycans at the basal epithelial surface that correlates with normal branching activity. Forty eight-hour cultures of cont...

journal_title：Developmental biology

authors： Spooner BS,Bassett K,Stokes B

更新日期：1985-05-01 00:00:00

abstract：:Optimal maturation of oocytes and successful development of preimplantation embryos is essential for reproduction. We performed DNA microarray analyses of ovarian transcripts and identified glial cell line-derived neurotrophic factor (GDNF) secreted by cumulus, granulosa, and theca cells as an ovarian factor stimulate...

journal_title：Developmental biology

authors： Kawamura K,Ye Y,Kawamura N,Jing L,Groenen P,Gelpke MS,Rauch R,Hsueh AJ,Tanaka T

更新日期：2008-03-01 00:00:00

abstract：:The nematode Caenorhabditis elegans has retained a rudimentary Hedgehog (Hh) signalling pathway; Hh and Smoothened (Smo) homologs are absent, but two highly related Patched gene homologs, ptc-1 and ptc-3, and 24 ptc-related (ptr) genes are present. We previously showed that ptc-1 is essential for germ line cytokinesis...

journal_title：Developmental biology

authors： Soloviev A,Gallagher J,Marnef A,Kuwabara PE

更新日期：2011-03-15 00:00:00

abstract：:Lineage analysis studies in the avian embryo have identified two types of smooth muscle cells (SMCs) in the tunica media of large elastic arteries; one that originates within the cardiac neural crest and is ectoderm in origin (Ect) and another that arises from local mesenchyme of mesodermal origin (Mes). To determine ...

journal_title：Developmental biology

authors： Topouzis S,Majesky MW

更新日期：1996-09-15 00:00:00

abstract：:Plants often display a high competence for regeneration under stress conditions. Signals produced in response to various types of stress serve as critical triggers for de novo organogenesis, but the identity of these signaling molecules underlying cellular reprogramming are largely unknown. We previously identified an...

journal_title：Developmental biology

authors： Iwase A,Mita K,Favero DS,Mitsuda N,Sasaki R,Kobayshi M,Takebayashi Y,Kojima M,Kusano M,Oikawa A,Sakakibara H,Saito K,Imamura J,Sugimoto K

更新日期：2018-10-01 00:00:00

abstract：:The cDNA encoding the TATA binding protein was isolated from 8- to 16-cell and morula-stage embryonic libraries of two distantly related species of sea urchin, Strongylocentrotus purpuratus and Lytechinus variegatus, respectively. The two proteins are 96% identical over both the N- and C-terminal domains, suggesting a...

journal_title：Developmental biology

authors： Edelmann L,Zheng L,Wang ZF,Marzluff W,Wessel GM,Childs G

更新日期：1998-12-01 00:00:00

abstract：:The term "transdifferentiation" has been used to describe the apparent phenotypic conversion of chick embryo neural retina Müller glial cells into lens-like cells in vitro. This phenotypic conversion is characterized by expression of such lens-specific proteins as delta crystallin and has been viewed as an example of ...

journal_title：Developmental biology

authors： Linser PJ,Irvin CK

更新日期：1987-06-01 00:00:00

abstract：:Tbx18 has been shown to be essential for ureteral development. However, it remains unclear whether it plays a direct role in kidney development. Here we addressed this by focusing on examining the pattern and contribution of Tbx18+ cells in the kidney and its role in kidney vascular development. Expression studies and...

journal_title：Developmental biology

authors： Xu J,Nie X,Cai X,Cai CL,Xu PX

更新日期：2014-07-01 00:00:00

abstract：:We have tested the role of proteoglycans in the development of feather pattern by culturing 7-day-old embryonic chick skins on medium containing para-nitrophenyl-beta-D-xyloside (2 mM). Xylosides compete with core proteins of proteoglycans by acting as exogenous acceptors for the synthesis of glycosaminoglycans leadin...

journal_title：Developmental biology

authors： Goetinck PF,Carlone DL

更新日期：1988-05-01 00:00:00

abstract：:The development of the reproductive system in Caenorhabditis elegans is a well-established model system for patterning and organogenesis. We report the characterization of the cog-1 gene, mutations in which cause novel phenotypes in late patterning in vulval lineages, establishment of the vulva-uterine connection, dev...

journal_title：Developmental biology

authors： Palmer RE,Inoue T,Sherwood DR,Jiang LI,Sternberg PW

更新日期：2002-12-15 00:00:00

abstract：:The human kidneys filter 180 l of blood every day via about 2.5 million glomeruli. The three layers of the glomerular filtration apparatus consist of fenestrated endothelium, specialized extracellular matrix known as the glomerular basement membrane (GBM) and the podocyte foot processes with their modified adherens ju...

journal_title：Developmental biology

authors： Kanasaki K,Kanda Y,Palmsten K,Tanjore H,Lee SB,Lebleu VS,Gattone VH Jr,Kalluri R

更新日期：2008-01-15 00:00:00

abstract：:Synapse elimination was examined in the developing frog cutaneous pectoris muscle using histological and electrophysiological techniques. Morphological synapse elimination occurred in two phases. The first phase, which began at the time of metamorphosis and continued until the second to third postmetamorphic week, was...

journal_title：Developmental biology

authors： Morrison-Graham K

更新日期：1983-10-01 00:00:00

abstract：:Animal development is controlled by gene regulation networks that are composed of sequence-specific transcription factors (TF) and cell signaling molecules (ST). Although housekeeping genes have been reported to show clustering in the animal genomes, whether the genes comprising a given regulatory network are physical...

journal_title：Developmental biology

authors： Shoguchi E,Hamaguchi M,Satoh N

更新日期：2008-04-15 00:00:00

abstract：:Analysis of 262 transgenic mouse pedigrees suggests that about 30% of the mice produced by microinjection of plasmids into pronuclei are mosaic in the germline. This implies that in these lines integration of the foreign DNA occurred after the first round of chromosomal DNA replication. In mosaics resulting from delay...

journal_title：Developmental biology

authors： Wilkie TM,Brinster RL,Palmiter RD

更新日期：1986-11-01 00:00:00

abstract：:Cells that overexpress PKA as a consequence of carrying multiple copies of the gene encoding the catalytic subunit can be induced to sporulate when developing as single cells. A peptide phosphorylated by PKA, termed SDF-1, has recently been shown to stimulate this process (Anjard et al., 1997). Several genes have been...

journal_title：Developmental biology

authors： Anjard C,Zeng C,Loomis WF,Nellen W

更新日期：1998-01-15 00:00:00

abstract：:Carbohydrate chains on the t12 mutant embryos were analyzed. No abnormalities of the synthesis of the carbohydrate chains were observed in the t12 homozygotes until the late morula stage, when radiolabeled carbohydrate chains were analyzed by Sephadex G-50 column chromatography. Furthermore, polarization of the Con A ...

journal_title：Developmental biology

authors： Iwakura Y,Nozaki M

更新日期：1988-08-01 00:00:00

abstract：:Pax3 is expressed early during embryonic development in spatially restricted domains including limb muscle, neural crest, and neural tube. Pax3 functions at the nodal point in melanocyte stem cell differentiation, cardiogenesis and neurogenesis. Additionally Pax3 has been implicated in migration and differentiation of...

journal_title：Developmental biology

authors： Nakazaki H,Reddy AC,Mania-Farnell BL,Shen YW,Ichi S,McCabe C,George D,McLone DG,Tomita T,Mayanil CS

更新日期：2008-04-15 00:00:00

abstract：:The msh/Msx family is a subclass of homeobox-containing genes suggested to perform a conserved function in the patterning of the early embryo. We had already isolated a member of this gene family (Ci-msxb) in Ciona intestinalis, which has a very complex expression pattern during embryogenesis. To identify the regulato...

journal_title：Developmental biology

authors： Russo MT,Donizetti A,Locascio A,D'Aniello S,Amoroso A,Aniello F,Fucci L,Branno M

更新日期：2004-03-15 00:00:00

abstract：:A simple assay has been developed to measure cGMP-specific phosphodiesterase (cGPD) activity in crude soluble extracts of amoebae of Dictyostelium discoideum. When amoebae of different wild-type strains were starved on buffered agar, all strains exhibited an 8- to 12-fold increase in cGMP-specific hydrolyzing activity...

journal_title：Developmental biology

authors： Coukell MB,Cameron AM,Pitre CM,Mee JD

更新日期：1984-05-01 00:00:00

abstract：:Mouse embryo limb cells carrying either the brachypodism (bpH/bpH) mutation or its wild-type (+/+) allele were tested for their ability to accumulate cyclic AMP in response to prostaglandin E2 (PGE2) between Embryonic Days E12 and E14. Mutant cells exhibited a precocious increase in cyclic AMP. In the absence of PGE2 ...

journal_title：Developmental biology

authors： Ballard TA,Elmer WA

更新日期：1990-12-01 00:00:00