Effect of prostaglandin E2 on cyclic AMP levels in limb cells of mouse mutant brachypodism.

abstract：:Initiation of transcription mediated by RNA polymerase II requires a number of transcription factors among which TFIID is the major core promoter recognition factor. TFIID is composed of highly conserved factors which include the TATA-binding protein (TBP) and about 14 TBP-associated factors (TAFs). Recently, the comp...

journal_title：Developmental biology

authors： Lago C,Clerici E,Dreni L,Horlow C,Caporali E,Colombo L,Kater MM

更新日期：2005-09-01 00:00:00

abstract：:We utilized a strain of mice, derived from a radiation mutagenesis experiment and carrying an activity-attenuated allele of the X-linked enzyme glucose-6-phosphate dehydrogenase (G6PD), to analyze the development of the cell lineage leading to cerebellar Purkinje neurons. Due to random X inactivation during early embr...

journal_title：Developmental biology

authors： Baader SL,Schilling ML,Rosengarten B,Pretsch W,Teutsch HF,Oberdick J,Schilling K

更新日期：1996-03-15 00:00:00

abstract：:The endoderm of C. elegans arises entirely from a single progenitor cell, the E blastomere, whose identity is specified by GATA type transcription factors, including END-1. In response to an inductive interaction mediated through Wnt/MAP kinase signaling pathways, POP-1, a Lef/Tcf-type transcription factor, restricts ...

journal_title：Developmental biology

authors： Witze ES,Field ED,Hunt DF,Rothman JH

更新日期：2009-03-01 00:00:00

abstract：:Development of the craniofacial structures requires the precise differentiation of cranial neural crest cells into osteoblasts or chondrocytes. Here, we explore the epigenetic and non-epigenetic mechanisms that are required for the development of craniofacial chondrocytes. We previously demonstrated that the acetyltra...

journal_title：Developmental biology

authors： Pezoa SA,Artinger KB,Niswander LA

更新日期：2020-08-01 00:00:00

abstract：:In this paper I sought to determine how the expression of differentiated traits of chick retinal pigmented epithelial (RPE) cells in vitro can be modulated by varying both the biochemical and the spatial complexity, and the mechanical properties, of the growth substratum. I have used glass derivatized with proteins of...

journal_title：Developmental biology

authors： Opas M

更新日期：1989-02-01 00:00:00

abstract：:Chicken talpid(3) mutant embryos have a wide range of Hedgehog-signalling related defects and it is now known that the talpid(3) gene product encodes a novel protein essential for Hedgehog signalling which is required for both activator and repressor functions of Gli transcription factors (Davey, M.G., Paton, I.R., Yi...

journal_title：Developmental biology

authors： Davey MG,James J,Paton IR,Burt DW,Tickle C

更新日期：2007-01-01 00:00:00

abstract：:The outgrowth of motor axons to the developing pectoral fin of the Japanese medaka fish (Oryzias latipes) was investigated both in wildtype embryos and in the pectoral finless (pl) mutants in which adults are missing pectoral fins. Late in embryogenesis the pectoral fin is a simple limb which contains two antagonist m...

journal_title：Developmental biology

authors： Okamoto H,Kuwada JY

更新日期：1991-07-01 00:00:00

abstract：:Genetic interactions regulating intermediate stages of tubulogenesis in the developing kidney have been difficult to define. A systems biology strategy using microarray was combined with in vitro/ex vivo and genetic approaches to identify pathways regulating specific stages of tubulogenesis. Analysis of the progressio...

journal_title：Developmental biology

authors： Gallegos TF,Kouznetsova V,Kudlicka K,Sweeney DE,Bush KT,Willert K,Farquhar MG,Nigam SK

更新日期：2012-04-01 00:00:00

abstract：:Multiciliated cells (MCCs) differentiate hundreds of motile cilia that beat to drive fluid movement over various kinds of epithelia. In Xenopus, mice and human, the coiled-coil containing protein Mcidas (Mci) has been shown to be a key transcriptional regulator of MCC differentiation. We have examined Mci function in ...

journal_title：Developmental biology

authors： Zhou F,Rayamajhi D,Ravi V,Narasimhan V,Chong YL,Lu H,Venkatesh B,Roy S

更新日期：2020-09-15 00:00:00

abstract：:Embryonic morphogenesis relies on the intrinsic ability of cells, often through remodeling the cytoskeleton, to shape epithelial tissues during development. Epithelial invagination is an example of morphogenesis that depends on this remodeling but the cellular mechanisms driving arrangement of cytoskeletal elements ne...

journal_title：Developmental biology

authors： Houssin NS,Martin JB,Coppola V,Yoon SO,Plageman TF Jr

更新日期：2020-06-01 00:00:00

abstract：:The developmental events of sporulation and fruiting body formation in the prokaryote Myxococcus xanthus are preceded by a stage of massive cell death. Two phenotypically complementable strains of M. xanthus defective in developmental lysis were identified from a group of conditional sporulation mutants. Mixture of th...

journal_title：Developmental biology

authors： Janssen GR,Dworkin M

更新日期：1985-11-01 00:00:00

abstract：:Neonatal mouse hearts fully regenerate after ventricular resection similar to adult zebrafish. We established cryoinjury models to determine if different types and varying degrees of severity in cardiac injuries trigger different responses in neonatal mouse hearts. In contrast to ventricular resection, neonatal mouse ...

journal_title：Developmental biology

authors： Darehzereshki A,Rubin N,Gamba L,Kim J,Fraser J,Huang Y,Billings J,Mohammadzadeh R,Wood J,Warburton D,Kaartinen V,Lien CL

更新日期：2015-03-01 00:00:00

abstract：:We have examined the expression of mRNAs encoding five major neurotransmitter-synthesizing enzymes in MAH cells, a clonal cell line derived by retroviral immortalization of a rat embryonic sympathoadrenal progenitor cell. These mRNAs include tyrosine hydroxylase (TH), choline acetyltransferase (ChAT), tryptophan hydro...

journal_title：Developmental biology

authors： Vandenbergh DJ,Mori N,Anderson DJ

更新日期：1991-11-01 00:00:00

abstract：:Although round spermatid injection can be used to create progeny for males who do not produce mature sperm, the rate of successful embryogenesis after such procedures is significantly lower than that for similar procedures using mature spermatozoa. The mechanisms underlying this difference are unknown. In this study, ...

journal_title：Developmental biology

authors： Kishigami S,Van Thuan N,Hikichi T,Ohta H,Wakayama S,Mizutani E,Wakayama T

更新日期：2006-01-01 00:00:00

abstract：:Fertilization overcomes meiotic arrest by triggering a series of biochemical events, resulting in activation of the egg. A small group of protein tyrosine kinases (PTKs) have been identified in eggs of invertebrates and lower vertebrates and inhibitor studies have suggested that they play a role in late events of egg ...

journal_title：Developmental biology

authors： Talmor A,Kinsey WH,Shalgi R

更新日期：1998-02-01 00:00:00

abstract：:The iris sphincter muscle consists of striated muscle fibers in the adult chicken. The ontogenetic development of this muscle has been studied by immunocytochemistry, from Embryonic Day 7 to the time of hatching. The time course of expression of specific markers of either smooth or striated muscle, i.e., smooth and sk...

journal_title：Developmental biology

authors： Volpe P,Biral D,Pizzo P,Salviati G,Margreth A

更新日期：1993-10-01 00:00:00

abstract：:HB-GAM (heparin-binding growth-associated molecule) is a secretory, extracellular matrix-associated protein that was isolated by screening for proteins that enhance neurite outgrowth in perinatal rat brain neurons. In the present study we have investigated the possible role of HB-GAM in cell proliferation in the devel...

journal_title：Developmental biology

authors： Szabat E,Rauvala H

更新日期：1996-08-25 00:00:00

abstract：:The development of the mammalian neocortex requires radial and tangential migration of cells. Radial migration of differentiated neurons from the ventricular zone (VZ) is well established. It is hypothesised that an earlier phase of tangential migration of mitotically active cells lays down a widespread periodically s...

journal_title：Developmental biology

authors： Wilkie AL,Jordan SA,Sharpe JA,Price DJ,Jackson IJ

更新日期：2004-03-01 00:00:00

abstract：:These studies examined the potential for reorganization and differentiation of dissociated 18-day fetal rat intestine. Cultures of trypsin-dissociated fetal intestine were maintained in vitro for 1 week on a three-dimensional matrix, then transplanted into syngeneic hosts. When harvested after 4 weeks, these transplan...

journal_title：Developmental biology

authors： Montgomery RK,Zinman HM,Smith BT

更新日期：1983-11-01 00:00:00

abstract：:The members of the transforming growth factor-beta (TGF-beta) superfamily are secreted proteins that interact with cell-surface receptors to elicit signals that regulate a variety of biological processes during vertebrate embryogenesis. Alk2, also known as ActRIA, Tsk7L, and SKR1, encodes a type I TGF-beta family rece...

journal_title：Developmental biology

authors： Mishina Y,Crombie R,Bradley A,Behringer RR

更新日期：1999-09-15 00:00:00

abstract：:A fundamental question in biology is how animal segmentation arose during evolution. One particular challenge is to clarify whether segmental ganglia of the nervous system evolved once, twice, or several times within the Bilateria. As close relatives of arthropods, Onychophora play an important role in this debate sin...

journal_title：Developmental biology

authors： Mayer G,Whitington PM

更新日期：2009-11-01 00:00:00

abstract：:Two 80- to 100-kb chromosomal replicons containing clustered chorion genes amplify in the ovarian follicle cells during the final 22 hr of Drosophila oogenesis. We have studied the relationship between amplification and transcription within one of these domains, located at 7E10-7F3,4 on the X chromosome. A tandem clus...

journal_title：Developmental biology

authors： Parks S,Wakimoto B,Spradling A

更新日期：1986-09-01 00:00:00

abstract：:The rabbit sperm membrane autoantigen RSA-1 is a sialoglycoprotein of 13,000 daltons which first appears on the surface of pachytene spermatocytes. Using specific antiserum to RSA-1 the antigen has been localized by immunofluorescence and immunoperoxidase staining. On testicular cells labeled at 37 degrees C, RSA-1 is...

journal_title：Developmental biology

authors： O'Rand MG,Romrell LJ

更新日期：1981-06-01 00:00:00

abstract：:The prostate gland develops from the urogenital sinus by a testosterone-dependent process of ductal morphogenesis. Sonic hedgehog (Shh) is expressed in the urogenital sinus epithelium and the time course of expression coincides with the formation of the main prostatic ducts. Expression is most abundant in the lumen of...

journal_title：Developmental biology

authors： Podlasek CA,Barnett DH,Clemens JQ,Bak PM,Bushman W

更新日期：1999-05-01 00:00:00

abstract：:Hedgehog (Hh) proteins are secreted molecules that play an essential role in development and tumorigenesis. In Drosophila cultured cells, phosphorylation of the kinesin-like Costal2 (Cos2) protein at Ser572 is triggered by the kinase fused (Fu) upon Hh pathway activation. Here, we validate the first phospho-antibody f...

journal_title：Developmental biology

authors： Raisin S,Ruel L,Ranieri N,Staccini-Lavenant L,Thérond PP

更新日期：2010-08-01 00:00:00

abstract：:How species-specific developmental timing is controlled is largely unknown. By following human embryonic stem (ES) cell and mouse epiblast stem (EpiS) cell differentiation through detailed RNA-sequencing time courses, here we show that pluripotent stem cells closely retain in vivo species-specific developmental timing...

journal_title：Developmental biology

authors： Barry C,Schmitz MT,Jiang P,Schwartz MP,Duffin BM,Swanson S,Bacher R,Bolin JM,Elwell AL,McIntosh BE,Stewart R,Thomson JA

更新日期：2017-03-15 00:00:00

abstract：:Recent studies with amoebae of the Myxomycetes Didymium iridis and Physarum polycephalum reveal that competence to undergo sexual fusion or to differentiate to plasmodia apogamically can be induced by a diffusible factor. Suspension cultures of Didymium amoebae have proven to be a good source of the inducer activity. ...

journal_title：Developmental biology

authors： Nader WF,Shipley GL,Huettermann A,Holt CE

更新日期：1984-06-01 00:00:00

abstract：:Biomineralization, the biologically controlled formation of mineral deposits, is of widespread importance in biology, medicine, and engineering. Mineralized structures are found in most metazoan phyla and often have supportive, protective, or feeding functions. Among deuterostomes, only echinoderms and vertebrates pro...

journal_title：Developmental biology

authors： Livingston BT,Killian CE,Wilt F,Cameron A,Landrum MJ,Ermolaeva O,Sapojnikov V,Maglott DR,Buchanan AM,Ettensohn CA

更新日期：2006-12-01 00:00:00

abstract：:Suppression of wing fate and specification of haltere fate in Drosophila by the homeotic gene Ultrabithorax is a classical example of Hox regulation of serial homology (Lewis, E.B. 1978. Nature 276, 565-570) and has served as a paradigm for understanding homeotic gene function. We have used DNA microarray analyses to ...

journal_title：Developmental biology

authors： Mohit P,Makhijani K,Madhavi MB,Bharathi V,Lal A,Sirdesai G,Reddy VR,Ramesh P,Kannan R,Dhawan J,Shashidhara LS

更新日期：2006-03-15 00:00:00

abstract：:Previous work has documented the importance of BMPs in eye development. Loss-of-function studies in mice, with targeted deletions in either the Bmp7 or Bmp4 genes, have shown that these molecules are critical for early eye development. On the basis of the asymmetry in the dorsal-ventral expression patterns of several ...

journal_title：Developmental biology

authors： Liu J,Wilson S,Reh T

更新日期：2003-04-01 00:00:00