Ontogenesis of chick iris intrinsic muscles: evidence for a smooth-to-striated muscle transition.

abstract：:Drosophila melanogaster mature oocytes in ovaries are arrested at metaphase I of meiosis. Eggs that have reached the uterus have released this arrest. It was not known where in the female reproductive tract egg activation occurs and what triggers it. We investigated when and where the egg is activated in Drosophila in...

journal_title：Developmental biology

authors： Heifetz Y,Yu J,Wolfner MF

更新日期：2001-06-15 00:00:00

abstract：:Polycomb group (PcG) proteins are best known for their role in maintaining stable, mitotically heritable silencing of the homeotic (HOX) genes during development. In addition to loss of homeotic gene silencing, some PcG mutants also have small imaginal discs. These include mutations in E(z), Su(z)12, esc and escl, whi...

journal_title：Developmental biology

authors： Mason-Suares H,Tie F,Yan CM,Harte PJ

更新日期：2013-08-01 00:00:00

abstract：:In most ascidians, metamorphosis of tadpole-like swimming larvae is accompanied by dynamic changes in their shape to form sessile adults. The mechanisms underlying ascidian metamorphosis have been debated for a long time. Although recent molecular studies have revealed the presence of various molecules involving in th...

journal_title：Developmental biology

authors： Nakayama-Ishimura A,Chambon JP,Horie T,Satoh N,Sasakura Y

更新日期：2009-02-15 00:00:00

abstract：:Two main processes are involved in driving ventral mesendoderm internalization in the Xenopus gastrula. First, vegetal rotation, an active movement of the vegetal cell mass, initiates gastrulation by rolling the peripheral blastocoel floor against the blastocoel roof. In this way, the leading edge of the internalized ...

journal_title：Developmental biology

authors： Ibrahim H,Winklbauer R

更新日期：2001-12-01 00:00:00

abstract：:During early heart development the expression pattern of N-cadherin, a calcium-dependent cell adhesion molecule, suggests its involvement in morphoregulation and the stabilization of cardiomyocyte differentiation. N-cadherin's adhesive activity is dependent upon its interaction with the intracellular catenins. An asso...

journal_title：Developmental biology

authors： Linask KK,Knudsen KA,Gui YH

更新日期：1997-05-15 00:00:00

abstract：:The distribution of microtubules and microtubule organizing centers in the events leading up to the establishment of the first asymmetric cleavage furrow in nematode embryos was followed using indirect immunofluorescence of antibodies to tubulin. Oocytes arrest in meiotic prophase then undergo two meiotic reduction di...

journal_title：Developmental biology

authors： Albertson DG

更新日期：1984-01-01 00:00:00

abstract：:Rhodopsin is essential for normal photoreceptor development in Drosophila (O'Tousa et al., 1989; Leonard et al., 1992; Kumar and Ready, 1995) and in mice (Humphries et al., 1997). Here we report studies in which a rhodopsin transgene is expressed at restricted stages during the development of Drosophila photoreceptors...

journal_title：Developmental biology

authors： Kumar JP,Bowman J,O'Tousa JE,Ready DF

更新日期：1997-08-01 00:00:00

abstract：:The formation of endocardial endothelium in quail embryos was investigated using in vivo and in vitro systems. Based on the expression of an quail endothelial marker, QH-1, the initial emergence of endothelial precursor cells in the embryo occurs at stage 7+ (two somites) in the posterior parts of the bilateral heart ...

journal_title：Developmental biology

authors： Sugi Y,Markwald RR

更新日期：1996-04-10 00:00:00

abstract：:Proper calcium channel and insulin signaling are essential for normal brain development. Leaner mice with a mutation in the P/Q-type voltage-gated calcium channel, Cacna1a, develop cerebellar atrophy and mutations in the homologous human gene are associated with increased migraine and seizure tendency. Similarly, abno...

journal_title：Developmental biology

authors： Estevez AO,Cowie RH,Gardner KL,Estevez M

更新日期：2006-10-01 00:00:00

abstract：:Oligodendrocytes are produced from the same region of the ventral spinal cord that earlier generated motor neurons in bird and rodent embryos. Motor neuron and oligodendrocyte precursor cells express Olig genes, which encode basic helix-loop-helix transcription factors that play important roles in the development of b...

journal_title：Developmental biology

authors： Park HC,Mehta A,Richardson JS,Appel B

更新日期：2002-08-15 00:00:00

abstract：:The members of the transforming growth factor-beta (TGF-beta) superfamily are secreted proteins that interact with cell-surface receptors to elicit signals that regulate a variety of biological processes during vertebrate embryogenesis. Alk2, also known as ActRIA, Tsk7L, and SKR1, encodes a type I TGF-beta family rece...

journal_title：Developmental biology

authors： Mishina Y,Crombie R,Bradley A,Behringer RR

更新日期：1999-09-15 00:00:00

abstract：:Stem cells play an essential role in cellular specialization and pattern formation during embryogenesis and in tissue regeneration in adults. This is mainly due to a stem cell's ability to replenish itself (self-renewal) and, at the same time, produce differentiated progeny. Realization of these special stem cell feat...

journal_title：Developmental biology

authors： Zhang J,Li L

更新日期：2005-08-01 00:00:00

abstract：:The tail ascidian larval peripheral nervous system is made up of epidermal sensory neurons distributed more or less regularly in ventral and dorsal midlines. Their formation occurs in two-steps: the ventral and dorsal midlines are induced as neurogenic territories by Fgf9/16/20 and Admp respectively. The Delta2/Notch ...

journal_title：Developmental biology

authors： Roure A,Darras S

更新日期：2016-01-01 00:00:00

abstract：:Artificial extracellular matrices composed of collagen, glycosaminoglycans (GAG), proteoglycans (PG), plasma fibronectin (FN), and a hyaluronate-binding protein (HABP) have been prepared that morphologically resemble embryonic extracellular matrices in vivo at the light and electron microscope level. The effect of eac...

journal_title：Developmental biology

authors： Turley EA,Erickson CA,Tucker RP

更新日期：1985-06-01 00:00:00

abstract：:Previous study of the development of the levator ani muscle (LA) revealed that the sex difference in muscle fiber number is under the control of testosterone during the perinatal period. In this study, the development of the LA muscle was examined in both sexes to test the hypothesis that testosterone action determine...

journal_title：Developmental biology

authors： Joubert Y,Tobin C,Lebart MC

更新日期：1994-03-01 00:00:00

abstract：:In vertebrates, the segmented somites, which are the medial-most component in the paraxial mesoderm, are the entity giving rise to the axial bones and skeletal muscles. We previously demonstrated that the mechanism that distinguishes the somite from the more lateral mesoderm (lateral plate) involves different levels o...

journal_title：Developmental biology

authors： Tonegawa A,Takahashi Y

更新日期：1998-10-15 00:00:00

abstract：:The development of the action potential and responses to neurotransmitters have been described for a population of embryonic spinal neurons developing in vivo. A comparable pattern is seen for spinal neurons developing in dissociated cell culture. The impulse appears very early in this developmental sequence, and the ...

journal_title：Developmental biology

authors： Bixby JL,Spitzer NC

更新日期：1984-11-01 00:00:00

abstract：:Initial studies suggested that spatial organization of the putative polar body contractile ring was determined by the peripheral aster in Spisula [Biol. Bull. 205 (2003) 192]. Here we report detailed supporting observations, including testing of aster and ring function with inhibitors. The metaphase peripheral aster w...

journal_title：Developmental biology

authors： Pielak RM,Gaysinskaya VA,Cohen WD

更新日期：2004-05-15 00:00:00

abstract：:We have examined the roles of cell lineage and interactions in the determination of individual identified neurons in the grasshopper embryo by selective ablations of individual cells and/or their neighbors at successive stages following their birth. The neurons in the grasshopper central nervous system (CNS) are produ...

journal_title：Developmental biology

authors： Kuwada JY,Goodman CS

更新日期：1985-07-01 00:00:00

abstract：:Most, if not all, endocrine cells seem capable of synthesizing and storing more than one hormone. Such cellular colocalization of hormones can be due either to the presence of two or more specific granules within the cells or to colocalization of the hormones within a single granule. The present study was performed to...

journal_title：Developmental biology

authors： Lukinius A,Ericsson JL,Grimelius L,Korsgren O

更新日期：1992-10-01 00:00:00

abstract：:The Endo16 gene codes for an RGD-containing calcium-binding protein that is found on the basal surfaces and in the extracellular matrix of cells of the invaginating archenteron during sea urchin gastrulation. Previously, we have shown that Endo16 is a single copy gene and we have determined the coding sequence and ana...

journal_title：Developmental biology

authors： Godin RE,Urry LA,Ernst SG

更新日期：1996-10-10 00:00:00

abstract：:In Drosophila, wing hairs are aligned in a distally oriented, parallel array. The frizzled pathway determines proximal-distal cell polarity in the wing; however, in frizzled pathway mutants, wing hairs remain parallel. How wing hairs align has not been determined. We have demonstrated a novel role for the septate junc...

journal_title：Developmental biology

authors： Venema DR,Zeev-Ben-Mordehai T,Auld VJ

更新日期：2004-11-15 00:00:00

abstract：:A cDNA of the sea urchin Strongylocentrotus purpuratus was identified as encoding polyubiquitin and used to detect a single gene with transcripts containing multiple ubiquitin coding units. Polyubiquitin transcripts exist as a 3.2-kb RNA in polyribosomes and as three higher molecular weight RNAs in purified nuclei. Th...

journal_title：Developmental biology

authors： Nemer M,Rondinelli E,Infante D,Infante AA

更新日期：1991-06-01 00:00:00

abstract：:In many organisms early embryogenesis is characterised by a period refractory to transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but at around eight-cell stage transcription is activated in the somatic lineage. This model suggests that histone tail modifications associated ...

journal_title：Developmental biology

authors： Wang S,Fisher K,Poulin GB

更新日期：2011-07-15 00:00:00

abstract：:Immunohistochemical analysis of myosin heavy chain (MHC) isoform expression in perinatal and adult rat diaphragm muscles was performed with antibodies which permitted the identification of all known MHC isoforms found in typical rat muscles. Isoform switching, leading to the emergence of the adult phenotype, was more ...

journal_title：Developmental biology

authors： LaFramboise WA,Daood MJ,Guthrie RD,Schiaffino S,Moretti P,Brozanski B,Ontell MP,Butler-Browne GS,Whalen RG,Ontell M

更新日期：1991-03-01 00:00:00

abstract：:Pax3/7 paired homeodomain transcription factors are important markers of muscle stem cells. Pax3 is required upstream of myod for lateral dermomyotomal cells in the amniote somite to form particular muscle cells. Later Pax3/7-dependent cells generate satellite cells and most body muscle. Here we analyse early myogenes...

journal_title：Developmental biology

authors： Hammond CL,Hinits Y,Osborn DP,Minchin JE,Tettamanti G,Hughes SM

更新日期：2007-02-15 00:00:00

abstract：:We report periodic movements during erection of Dictyostelium discoideum (Dd) sorocarps. Our observations lead to the working hypothesis that Dd sorocarp erection occurs by two superimposed processes: one periodic, with a modal period of 6 1/2 min, and one continuous. We tentatively identify the periodic process with ...

journal_title：Developmental biology

authors： Durston AJ,Cohen MH,Drage DJ,Potel MJ,Robertson A,Wonio D

更新日期：1976-09-01 00:00:00

abstract：:The stromal microenvironment regulates mammary gland branching morphogenesis. We have observed that mast cells are present in the mammary gland throughout its postnatal development and, in particular, are found around the terminal end buds and ductal epithelium of the pubertal gland. Mast cells contribute to allergy, ...

journal_title：Developmental biology

authors： Lilla JN,Werb Z

更新日期：2010-01-01 00:00:00

abstract：:Urodele amphibians can regenerate their limbs. During limb regeneration, dermal fibroblasts are transformed into undifferentiated cells called blastema cells. These dermis-blastema cells show multipotency. Such so-called endogenous reprogramming of cell differentiation is one of the main targets of amphibian limb rege...

journal_title：Developmental biology

authors： Makanae A,Hirata A,Honjo Y,Mitogawa K,Satoh A

更新日期：2013-09-01 00:00:00

abstract：:The protein tyrosine phosphatase PTP1, which mediates reversible phosphorylation on tyrosine, has been shown to play an important regulatory role during Dictyostelium development. Mutants lacking PTP1 develop more rapidly than normal, while strains that overexpress PTP1 display aberrant morphology. However, the signal...

journal_title：Developmental biology

authors： Early A,Gamper M,Moniakis J,Kim E,Hunter T,Williams JG,Firtel RA

更新日期：2001-04-01 00:00:00