Abstract：
:The rabbit sperm membrane autoantigen RSA-1 is a sialoglycoprotein of 13,000 daltons which first appears on the surface of pachytene spermatocytes. Using specific antiserum to RSA-1 the antigen has been localized by immunofluorescence and immunoperoxidase staining. On testicular cells labeled at 37 degrees C, RSA-1 is seen in patches on the surfaces of pachytene spermatocytes, round spermatids, and over the acrosomal area of later spermatids and spermatozoa. Over the postacrosomal and middle-piece regions of late spermatids and spermatozoa the labeling appears uniform. The uniformity can be seen to stop abruptly at the equatorial segment-postacrosomal border. Labeling cells after fixation gives a uniform distribution of label over the surface where patches were seen at 37 degrees C. The polypeptides recognized by the antiserum used for labeling were identified by immunoadsorbent chromatography and subsequent SDS-PAGE. In testicular cells anti-RSA-1 recognizes the 13,000-dalton form and another component which migrates with the dye front. In ejaculated spermatozoa anti-RSA-1 recognizes a distinct ejaculate complex of higher-molecular-weight proteins containing an 84,000-dalton major band and five minor components.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
O'Rand MG,Romrell LJdoi
10.1016/0012-1606(81)90400-0subject
Has Abstractpub_date
1981-06-01 00:00:00pages
322-31issue
2eissn
0012-1606issn
1095-564Xpii
0012-1606(81)90400-0journal_volume
84pub_type
杂志文章abstract：:In the full grown oocyte of Xenopus laevis, a sodium permeability can be induced by depolarization to positive potential with current injection. Voltage-clamp analysis has shown that depolarization causes a long-lasting modification of the membrane during which voltage-gated sodium channels become functional. In the p...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(83)90302-0
更新日期：1983-10-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章,评审
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更新日期：2004-01-01 00:00:00
abstract：:Myoblast fusion (a critical process by which muscles grow) occurs in a multi-step fashion that requires actin and membrane remodeling; but important questions remain regarding the spatial/temporal regulation of and interrelationship between these processes. We recently reported that the Rho-GAP, GRAF1, was particularl...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2014.06.025
更新日期：2014-09-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1995.1266
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(83)90004-0
更新日期：1983-01-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.02.013
更新日期：2008-05-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2017.10.016
更新日期：2017-12-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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abstract：:The chick spinal cord can regenerate following injury until advanced developmental stages. It is conceivable that changes in stem/progenitor cell plasticity contribute to the loss of this capacity, which occurs around E13. We investigated the contribution of proliferation, phenotypic changes in radial glia progenitors...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2009-08-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2004.10.014
更新日期：2005-02-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章,评审
doi：10.1016/0012-1606(85)90461-0
更新日期：1985-06-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(92)90122-w
更新日期：1992-10-01 00:00:00
abstract：:BMP signaling responses are refined by distinct secreted and intracellular antagonists in different cellular and temporal contexts. Here, we show that the nuclear LEM-domain protein MAN1 is a tissue-specific antagonist of BMP signaling in Drosophila. MAN1 contains two potential Mad-binding sites. We generated MAN1Delt...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2009.11.036
更新日期：2010-03-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2011.07.006
更新日期：2011-10-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2012.08.003
更新日期：2012-11-01 00:00:00
abstract：:Early (alpha) histone genes are one of several histone gene families in the sea urchin genome. They are expressed at high levels in blastula-stage embryos and are inactivated by the early gastrula stage. By microinjecting mutant early H2B genes into sea urchin zygotes and monitoring their transcriptional activity in b...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(92)90248-f
更新日期：1992-04-01 00:00:00
abstract：:The development of the vertebrate inner ear is a complex process that has been investigated in several model organisms. In this work, we examined genetic interactions regulating early development of otic structures in medaka. We demonstrate that misexpression of Fgf8, Dlx3b and Foxi1 during early gastrulation is suffi...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2007.04.022
更新日期：2007-07-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.2000.0127
更新日期：2001-03-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1999-02-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1996.0073
更新日期：1996-03-15 00:00:00
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更新日期：2011-08-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2003.07.010
更新日期：2003-11-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2006.03.010
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2004.02.024
更新日期：2004-06-01 00:00:00
abstract：:In the head of an embryo, a layer of mesenchyme surrounds the brain underneath the surface ectoderm. This cranial mesenchyme gives rise to the meninges, the calvaria (top part of the skull), and the dermis of the scalp. Abnormal development of these structures, especially the meninges and the calvaria, is linked to si...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2019-11-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1991-08-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1985-01-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2010.12.022
更新日期：2011-03-01 00:00:00
abstract：:The transcription factors GATA4, GATA5 and GATA6 are important regulators of heart muscle differentiation (cardiomyogenesis), which function in a partially redundant manner. We identified genes specifically regulated by individual cardiogenic GATA factors in a genome-wide transcriptomics analysis. The genes regulated ...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2017.11.017
更新日期：2018-02-01 00:00:00
