Abstract：
OBJECTIVE:To examine the relationship between weight gain, changes in body composition and physiological characteristics of fitness during the recovery from anorexia nervosa. DESIGN:Longitudinal over eight weeks of intensive inpatient re-feeding (Wk 0-8). SETTING:The London Hospital Medical College. SUBJECTS:Ten female patients who agreed to participate. Seven completed the protocol. INTERVENTIONS:Dual-energy X-ray absorptiometry (dexa) and skinfold thickness measures at Wk 0 and 8. Weekly measures of peak expiratory flow rate and cycle ergometry (several variables relating to aerobic work recorded at rest and during cycling at low loads (0-60 W)). Blood samples for lactate and potassium measures, taken during cycling at Wk 0, 4 and 8 only. RESULTS:(1) Body composition: Mean weight gain over eight weeks was 9.6 kg, dexa and skinfold measures showing fat gain to contribute 62% and 54%, respectively. Both methods showed significant changes in percentage body fat with refeeding (P < 0.01 and P < 0.001, respectively), however there were significant differences in results between methods before (P < 0.01) but not after (P = 0.2) refeeding. (2) Physiological function: Between weeks 0 and 8, mean peak expiratory flow rate rose to 85% of predicted values, cycle ergometry performance improved in six subjects (three never reached 60 W load), mean respiratory exchange ratio (RER) during cycling fell at 0 W and 20 W loads (both P < 0.05), and oxygen pulse increased at rest and 0 W load cycling (both P < 0.05), Wk 8 values being well below normal. Oxygen uptake at rest and all loads increased in line with body weight gain only. No significant changes were seen in heart rate or blood lactate and potassium levels. CONCLUSIONS:(1) Lean body and fat mass increased significantly during eight weeks of refeeding. The methodological difference in initial body fat measurements requires further investigation. (2) The women had severely impaired physiological function. Variables studied were only slowly improving with refeeding, and work capacity was still well below normal.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Waller EG,Wade AJ,Treasure J,Ward A,Leonard T,Powell-Tuck Jsubject
Has Abstractpub_date
1996-03-01 00:00:00pages
165-70issue
3eissn
0954-3007issn
1476-5640journal_volume
50pub_type
杂志文章abstract：OBJECTIVE:To assess the usefulness of fat-free mass (FFM) as an index of total body protein (TBPr) status in continuous ambulatory peritoneal dialysis (CAPD) patients. DESIGN:TBPr was measured by in vivo neutron activation analysis (IVNAA) and expressed as a standardised protein index (PI). FFM was estimated by dual e...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVE:To investigate the lipid content and fatty acid (FA) composition, especially n(3) long-chain polyunsaturated fatty acids (n(3) LCPUFAs) of mature breast-milk of Iraqi mothers and their relation to the socioeconomic status of the mothers. DESIGN:A collection of mature breast-milk of mothers with three differe...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602470
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Sifted flour was fortified with carbonyl iron for 50 years in Sweden. This study evaluates changes in food habits, intake of iron, factors affecting iron absorption and iron status after the discontinuation of the general iron fortification in adolescents with the highest requirements. SUBJECTS/M...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.291
更新日期：2015-04-01 00:00:00
abstract：:The additional energy requirements of pregnancy are needed for increases in maternal (breast, uterus and adipose) and feto-placental tissue accrued during pregnancy as well as the additional running cost of pregnancy for example increased cardiac output. Based on prospective longitudinal studies, the additional energy...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1600753
更新日期：1999-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Several studies have addressed the validity of ultrasound (US) for body composition assessment, but few have evaluated its reliability. This study aimed to determine the reliability of percent body fat (%BF) estimates using A-mode US in a heterogeneous sample. SUBJECTS/METHODS:A group of 144 heal...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00743-y
更新日期：2020-09-11 00:00:00
abstract：BACKGROUND:Human milk vitamin B12 (B12) concentrations depend on maternal status and intake; only few data are available in high-income countries. OBJECTIVE:We assessed human milk B12 concentrations during the first 6 months postpartum in Norwegian women and its association with maternal dietary B12 intake and materna...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-0567-x
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To compare if postprandial glucose and insulin responses to wholekernel rye bread are lower than to wheat bread, and to see if these responses to two types of rye breads are different. To explore starch digestion in more detail, rate of starch hydrolysis of same breads was measured in vitro. DESIGN:Subjects ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600716
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. DESIGN:A case-control study conducted in Italy. SUBJECTS:The subjects were 1225 colon cancer patients, 728 rectal cancer patients and...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601317
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE:There are still controversies as to the potential beneficial effects of milk and fermented milk products on the level of lipoproteins. The objective of the present investigation was to test the effect of a moderate daily intake of a new fermented milk product, which was based on a bacterial culture obtained f...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Urinary and plasma indices are utilized to assess whole-body water balance in healthy adults, whereas the urine-to-plasma osmolality ratio (Uosm:Posm) rarely is. To explore the efficacy of Uosm:Posm as a hydration biomarker, diet records of 120 college women were analyzed (beverage water+food wate...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2013.79
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:We investigated the effects of mineral water fortified with folic acid, vitamins B(6), B(12), D and calcium on folate concentrations in serum and erythrocytes, serum vitamin B(12) and plasma homocysteine concentrations in free-living subjects. In addition, we investigated the bioavailability of calcium added ...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601795
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:To assess the bioavailability of vitamins A and E administered parenterally with either water-soluble or lipid-soluble preparations. STUDY DESIGN:A water soluble preparation (MVI Pediatric) administered with a glucose-amino acid solution and a lipid soluble preparation (Vitalipid N Infant) infused with a lip...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601417
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:These two studies compared the subjective assessment of how filling a snack type would be, with actual consumption of that type of snack at a snack meal. DESIGN:Four snack types: savory high-fat, savory high-carbohydrate, sweet high-carbohydrate, each comprising of five food items, were used. Study 1 consist...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：OBJECTIVE:To investigate the impact of irregular meal frequency on circulating lipids, insulin, glucose and uric acid concentrations which are known cardiovascular risk factors. DESIGN:A randomised crossover dietary intervention study. SETTING:Nottingham, UK--Healthy free-living women. SUBJECTS:A total of nine lean ...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601935
更新日期：2004-07-01 00:00:00
abstract：:More than a decade has passed since it was unintentionally discovered that grapefruit juice interacts with certain drugs. The coadministration of these drugs with grapefruit juice can markedly elevate drug bioavailability, and can alter pharmacokinetic and pharmacodynamic parameters of the drug. The predominant mechan...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1601736
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:The content of n-3 (omega-3) polyunsaturated fatty acids in fat tissue is a valid indicator of their long-term consumption. We studied the stability of n-3 fatty acids in human subcutaneous fat microbiopsies after 6 and 11 y of storage. DESIGN:Microbiopsies were taken from a lump of human adipose tissue and...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601614
更新日期：2003-07-01 00:00:00
abstract：:Insulin resistance is common and is determined by physiological (aging, physical fitness), pathological (obesity) and genetic factors. The metabolic compensatory response to insulin resistance is hyperinsulinaemia, the primary purpose of which is to maintain normal glucose tolerance. The 'carnivore connection' postula...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1601351
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Obesity and metabolic disorders are linked to inflammation via gut microbiota and/or gut permeability. Gut-derived endotoxin triggers inflammation leading to metabolic syndrome (MetS) and contributing to oxidative stress. We intended to investigate the effect of Lactobacillus casei Shirota on gut ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2012.103
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The Dutch guidelines for a healthy diet aim to reduce major chronic diseases. However, supporting evidence on their overall association with all-cause and cause-specific mortality is limited. Recently, the Dutch Healthy Diet-index (DHD-index) has been developed to assess adherence to these guideli...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.163
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To study the variation in selenoprotein P levels in serum among healthy subjects from 17 European regions representing nine countries. SUBJECTS:Survey of 414 37-70-year-old subjects (197/217 males/females) from 17 regions. RESULTS:The level of selenoprotein P varied significantly among regions and countries...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Despite the fact that both thiamine deficiency (TD) and Wernicke encephalopathy (WE) have been observed to some degree in cancer patients, such cases of TD and/or WE reported to date have all been diagnosed after the initiation of treatment. We here report a case of TD that presented without the commonly accepted tria...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00735-y
更新日期：2020-09-07 00:00:00
abstract：OBJECTIVE:To study dietary lipid intake and plasma lipid profile of the Hong Kong Chinese population as part of a territory wide survey on cardiovascular risk factors. DESIGN:Randomised age and sex stratified survey. SUBJECTS:1010 subjects aged 25-74 y (500 men, 510 women). MEASUREMENTS:A food frequency method with ...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1600430
更新日期：1997-07-01 00:00:00
abstract：:Comparison of percent fat mass across different body composition analysis devices is important given variation in technology accuracy and precision, as well as the growing need for cross-validation of devices often applied across longitudinal studies. We compared EchoMRI-AH and Lunar iDXA quantification of percent bod...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.236
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Infancy may be a sensitive period regarding effects of sodium intake on future blood pressure (BP). This has only been demonstrated in one randomized trial of low sodium formulae with follow-up in adolescence in one-third of participants. OBJECTIVE:To prospectively assess associations between sodium intake ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602837
更新日期：2008-10-01 00:00:00
abstract：OBJECTIVE:To study the effect of infection on iron status in children suffering from acute, mild or severe respiratory infections and to determine the nature of anemia in infection using serum transferrin receptor (sTfR) levels. DESIGN:Forty-three children aged between 3 and 5 y with no evidence of infection and recei...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601496
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To explore the associations between serum concentrations of vitamin D (25(OH)D) and all-cause mortality among US adults defined by lung function (LF) status, particularly among adults with obstructive LF (OLF). METHODS:Data from 10,795 adults aged 20-79 years (685 with restrictive LF (RLF) and 1309 with OLF)...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.162
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There are positive associations between pulmonary function (PF) and fat-free mass as well as muscle strength. Contrarily, negative associations were found with indirect measures of visceral adipose tissue (VAT). We aimed to differentiate between associations of body composition and PF by assessing...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.146
更新日期：2017-03-01 00:00:00
abstract：:Diet may both increase and decrease oxidative stress in the body. We compared the effects of four strictly controlled isocaloric diets with different intakes of polyunsaturated fatty acids (PUFA, 11 or 3% of energy) and vegetables and fruit (total amount of vegetables and fruit 516 or 1059 g/10 MJ) on markers associat...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章
doi：10.1038/sj.ejcn.1602865
更新日期：2008-09-01 00:00:00
abstract：:Food fortification can deliver essential micronutrients to large population segments without modifications in consumption pattern, suggesting that fortified foods may be formulated for populations at risk for fragility fractures. This scoping review determined the extent to which randomized controlled studies have bee...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2016.42
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:This cross-sectional study aimed to estimate total antioxidant capacity (TAC) intake from food and beverages in a Japanese population from 7-day seasonal dietary records. SUBJECTS/METHODS:The 7-day weighed dietary records of 390 subjects over four seasons between 1996 and 1998 were used. The TAC ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2014.65
更新日期：2014-07-01 00:00:00
