Abstract：
:Food fortification can deliver essential micronutrients to large population segments without modifications in consumption pattern, suggesting that fortified foods may be formulated for populations at risk for fragility fractures. This scoping review determined the extent to which randomized controlled studies have been carried out to test the impact of fortified foods on bone outcomes, searching PubMed for all studies using the terms 'fortified AND bone', and 'fortification AND bone'. Studies were restricted to English language, published between 1996 and June 2015. From 360 articles, 24 studies met the following criteria: human study in adults ⩾18 years (excluding pregnancy or lactation); original study of a fortified food over time, with specific bone outcomes measured pre- and post intervention. Six studies involved adults <50 years; 18 involved adults ⩾50 years. Singly or in combination, 17 studies included calcium and 16 included vitamin D. There were 1 or 2 studies involving either vitamin K, magnesium, iron, zinc, B-vitamins, inulin or isoflavones. For adults <50 years, the four studies involving calcium or vitamin D showed a beneficial effect on bone remodeling. For adults ⩾50 years, n=14 provided calcium and/or vitamin D, and there was a significant bone turnover reduction. No consistent effects were reported in studies in which addition of vitamin K, folic acid or isoflavone was assessed. Results from this scoping review indicate that up to now most studies of fortification with bone health have evaluated calcium and/or vitamin D and that these nutrients show beneficial effects on bone remodeling.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Whiting SJ,Kohrt WM,Warren MP,Kraenzlin MI,Bonjour JPdoi
10.1038/ejcn.2016.42subject
Has Abstractpub_date
2016-10-01 00:00:00pages
1099-1105issue
10eissn
0954-3007issn
1476-5640pii
ejcn201642journal_volume
70pub_type
杂志文章,评审abstract：OBJECTIVES:Swedish Obese Subjects (SOS) is a multidisciplinary project involving aspects of obesity ranging from description of the severely obese state to effects of surgical intervention on long-term mortality and morbidity. Dietary studies, which represent an integral part of SOS research activities, are the focus o...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1600567
更新日期：1998-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Anemia, leukopenia and, although less frequently, thrombocytopenia are possible hematological complications of anorexia nervosa considered strictly secondary to chronic malnutrition. This is a retrospective study on the prevalence of these disorders in a large cohort of 318 female patients with AN...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.115
更新日期：2016-11-01 00:00:00
abstract：:A low-cost locally based nutrition education programme was designed around the employment of a part-time dietitian with the aim of improving the nutritional intakes of Grampian Health Board staff. Its effectiveness was evaluated by assessment of habitual dietary intakes of staff, using a previously validated questionn...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：OBJECTIVE:We examined the relation between intake of natural dietary plant sterols and serum lipid concentrations in a free-living population. DESIGN, SETTING AND PARTICIPANTS:Cross-sectional population-based study of 22,256 men and women aged 39-79 y resident in Norfolk, UK, participating in the European Prospective ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601980
更新日期：2004-10-01 00:00:00
abstract：:This study was conducted to follow up healthy subjects from a previous study (Warwick & Williams, 1987) in which favourable dietary changes were achieved during 1 week immediately after dietary advice but were accompanied by reduced energy intakes and weight loss. Twenty-one subjects (8m, 13f; 57 per cent of the origi...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：:The fundamental principles of energy physiology were used to evaluate the validity of reported energy intake (EI) in 37 published dietary studies of adults providing 68 subgroups when classified according to sex and dietary method. EI was expressed as a multiple of BMR estimated using the reported heights and weights ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1991-12-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Adult skeletal muscle mass (SMM) protects against type 2 diabetes, but little is known about its developmental antecedents. We examined whether pace of early weight gain predicted adult SMM in a birth cohort from Cebu City, Philippines. In addition, we examined whether increases in SMM associated ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.18
更新日期：2015-12-01 00:00:00
abstract：:As type 2 diabetes mellitus (DM2), obesity and sedentary lifestyles are increasing in developing countries, this observational study investigated the role of physical activity on DM2 in Jamaica. Anthropometry, body composition (by bioelectrical impedance analysis) and glucose tolerance status was assessed in 722 adult...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602011
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVES:The acute phase response (APR) influences indicators of iron status. A recent WHO/CDC consultation recommended concurrent measurement of alpha-1-acid-glycoprotein (AGP) in surveys to control for the APR, and aid in interpreting iron status. They proposed further exploratory analyses using AGP. We examined wh...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2008.33
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The risk factors for metabolic syndrome may differ between Western and Asian countries due to their distinct dietary cultures. However, few studies have directly compared macronutrient intake and its association with the risk of metabolic syndrome in the US and Korean adults using national survey ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-017-0031-8
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The majority of hospital outpatients with undernutrition is unrecognized, and therefore untreated. There is a need for an easy and valid screening tool to detect undernutrition in this setting. The aim of this study was to determine the diagnostic accuracy of the MUST (Malnutrition Universal Scree...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究
doi：10.1038/ejcn.2013.85
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Mild cognitive impairment (MCI), often considered as an early stage of dementia, is heterogeneous, and not all subjects with MCI progress into clinically diagnosed dementia. Low body weight (and body mass index, BMI) as well as losing weight while in MCI stadium have been proposed as possible risk...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2014.167
更新日期：2014-11-01 00:00:00
abstract：:To study the role of diet, 197 patients of essential hypertension were randomized to either experimental diet (group A, 97 cases) or normal diet (group B, 100 cases) with diuretics given to both the groups. The age varied between 25 and 65 years and 154 were males. The study diet included a significantly higher conten...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Urinary and plasma indices are utilized to assess whole-body water balance in healthy adults, whereas the urine-to-plasma osmolality ratio (Uosm:Posm) rarely is. To explore the efficacy of Uosm:Posm as a hydration biomarker, diet records of 120 college women were analyzed (beverage water+food wate...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2013.79
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings. SUBJECTS/METHODS:This is an observational analysis of 1078 HIV-infected pregnant women enrolled in a trial of vitamin supp...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2010.76
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Glucagon-like-peptide-1 (7-36) amide (GLP-1) is an insulin secretagogue and potential treatment for type II diabetes mellitus. An alternative to GLP-1 administration is endogenous dietary stimulation. We described a greater GLP-1 release following ingestion of liquids versus solids. We add to t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602654
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To measure the lipid content and the fatty acid (FA) composition of breast milk as part of a nutritional survey of the essential fatty acid (EFA) status of 5 months old Congolese infants. DESIGN:Cross sectional nutrition survey. SETTING:A suburban district of Brazzaville (capital of the Congo). SUBJECTS:A ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600529
更新日期：1998-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Previous research has shown, in predominantly European populations, that dietary patterns are evident early in life. However, little is known about early-life dietary patterns in Australian children. We aimed to describe dietary patterns of Australian toddlers and their associations with socio-dem...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/ejcn.2013.23
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations. METHODS:This study enrolled 100 healthy young adults aged 18-34 years. Ant...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2008.48
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVES:To investigate the effect of three different food ingredients tyrosine, green tea extract (GTE) and caffeine on resting metabolic rate and haemodynamics, and on ad libitum energy intake (EI) and appetite. METHODS:Twelve healthy, normal weight men (age: 23.7 +/- 2.6 years, mean +/- s.d.) participated in a fo...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602901
更新日期：2009-01-01 00:00:00
abstract：:Postprandial thermogenesis was assessed by indirect calorimetry in 32 Gambian women classified into three groups as follows: 12 non-pregnant non-lactating and 10 lactating women studied during the dry season and 10 lactating women studied during the rainy season. The test meal consisted of a typical Gambian breakfast ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The growth literature from developing countries is reviewed to assess the extent to which stunting, a phenomenon of early childhood, can be reversed in later childhood and adolescence. The potential for catch-up growth increases as maturation is delayed and the growth period is prolonged. However, maturational delays ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Exclusive enteral nutrition (EEN) is a safe and effective treatment modality for inducing remission in paediatric Crohn's disease (CD). The primary aim of this study was to compare the outcomes of EEN to corticosteroid (CS) therapy in newly diagnosed, treatment-naïve patients with CD. A secondary ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2016.210
更新日期：2017-02-01 00:00:00
abstract：:The association of calcium intake with risk of developing hypertension in the general population has not been established yet. We systematically searched PubMed and Scopus databases up to February 2018 to find prospective observational studies investigating the association of calcium intake with risk of developing hyp...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,meta分析
doi：10.1038/s41430-018-0275-y
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to compare red blood cell (RBC) fatty acid composition, plasma lipids and lipoproteins and dietary intake between urban and rural Melanesian Fijians. DESIGN:A cross-sectional study was performed in a random subsample (n = 154) from a total survey population of 589 subjects. SETTING:...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:We examined the relationships between insulin sensitivity (IS), skeletal muscle (SM) mass and SM quality in youth. Forty obese adolescent boys (body mass index ≥ 95 th percentile, 12-18 years) participated in this study. IS and glucose tolerance was measured by a 3 h hyperinsulinemic-euglycemic clamp and a 2 h oral gl...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2012.142
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:This study examined the prevalence of obesity and hypertension and associated behavioral risk factors in adult men and women in Uzbekistan. The study also examined the association between obesity and hypertension. METHOD:The analysis used data from the 2002 Uzbekistan Health Examination Survey, which include...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602465
更新日期：2006-12-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to assess the effects of fish oil supplementation in pregnancy on maternal erythrocyte fatty acid composition at different stages of pregnancy and in the post-partum period, and on neonatal erythrocyte fatty acid composition. DESIGN:A double-blind, randomised, placebo-controlled stu...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601825
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:To explore the different characteristics of high and low fat consumers, in particular their macronutrient intake and body mass index. DESIGN:Reanalysis of data from the Dietary and Nutritional Survey of British Adults. Comparisons were made between groups defined as high and low fat consumers on the basis o...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVE:To assess the carotenoid status in young type I diabetic patients and its relationship to the glycaemic control of the disease. DESIGN:A follow-up study. SETTING:Hospital Universitario Puerta de Hierro, Health Area VI of Madrid (Spain). SUBJECTS:Forty-seven type I diabetic patients, followed for 2.5 years....
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602411
更新日期：2006-08-01 00:00:00
