Abstract:
:The additional energy requirements of pregnancy are needed for increases in maternal (breast, uterus and adipose) and feto-placental tissue accrued during pregnancy as well as the additional running cost of pregnancy for example increased cardiac output. Based on prospective longitudinal studies, the additional energy requirements of pregnancy range from > 500 MJ in Swedish women to net savings of approximately 50 MJ in women in The Gambia with their usual nutritional intake. In addition to the wide variation in estimated energy expenditure among various ethnic populations, there is as much as a 10-20 fold range in the total energy cost of pregnancy and lactation within relatively homogenous populations. The estimates of energy intake in these studies, however, are generally less than the estimates of total energy expenditure. The discrepancy between energy intake and energy expenditure during pregnancy is most probably due to several factors including decreased maternal activity, unreliable reporting of energy intake and possibly increased metabolic efficiency of basal metabolic rate, thermic effect of foods and physical activity. Based on recent studies, variations in maternal pregravid glucose insulin sensitivity may account for part of the observed variability associated with maternal metabolic adaptations during pregnancy. Decreases in insulin sensitivity have a significant inverse correlation with accretion of adipose tissue in early pregnancy. Likewise, there is a significant inverse correlation between decreases in basal oxygen consumption with increases in endogenous glucose production. The mechanism for these changes remain speculative. Additionally, although serum leptin concentrations increase 66% in early pregnancy and are correlated with maternal fat mass and basal energy expenditure, the increases in serum leptin occur prior to any significant increases in body fat or basal metabolic rate suggesting that pregnancy represents another leptin resistant state. Based on these data, specific recommendations for acceptable carbohydrate and fat intake during pregnancy and lactation are not possible for every woman at this time. Additional prospective studies, evaluating long-term maternal and neonatal outcome are needed before more meaningful nutritional recommendations can be proposed.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Catalano PMdoi
10.1038/sj.ejcn.1600753subject
Has Abstractpub_date
1999-04-01 00:00:00pages
S124-31; discussion S131-5eissn
0954-3007issn
1476-5640journal_volume
53 Suppl 1pub_type
杂志文章,评审abstract:OBJECTIVE:To elucidate gender differences in dietary intake among adults in lowland Nepalese communities. SUBJECTS AND METHODS:For 122 male and 195 female subjects aged 20 years and over from 94 randomly selected households, interviews using a 19-item food frequency questionnaire were conducted. To determine the porti...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602339
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVES:This study aimed to examine the relationship between total pregnancy weight gain, maternal educational level, working status and infant birth weight among mothers and infants in urban health centers in Rasht, Iran. DESIGN:Pregnant women from six different public health centers in urban areas were studied in...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602239
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:We examined the relation between intake of natural dietary plant sterols and serum lipid concentrations in a free-living population. DESIGN, SETTING AND PARTICIPANTS:Cross-sectional population-based study of 22,256 men and women aged 39-79 y resident in Norfolk, UK, participating in the European Prospective ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601980
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk retinol concentration. METHODS:Fifty low income women were randomly assigned to a single oral dose of 209 micromol of Vitamin A or none at delivery. Maternal serum and breastmilk retinol levels and infant morbidity and ant...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600398
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:Studies have shown that depression relates to biomarkers of both short- and long-term polyunsaturated fatty acid (PUFA) intake. However, it is not known which of these two biomarkers has the closest relationship to depression. OBJECTIVE:To examine the relationship of depression with both adipose tissue and ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602413
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:To assess the carotenoid status in young type I diabetic patients and its relationship to the glycaemic control of the disease. DESIGN:A follow-up study. SETTING:Hospital Universitario Puerta de Hierro, Health Area VI of Madrid (Spain). SUBJECTS:Forty-seven type I diabetic patients, followed for 2.5 years....
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602411
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In international surveys of food consumption and nutrient intake, it is essential that the dietary data are comparable when different databases and calculation programs are used. The aim of the present analysis was to examine the comparability of nutrient intake data calculated on the basis of ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601639
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients. SUBJECTS/METHODS:Handgrip strength was measured with Jamar dynamometer in 620 hospitalized patients (56.4±15.9 years old, 52.3...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.261
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Heavy alcohol drinking is a risk factor of colorectal cancer (CRC), but little is known on the effect of polymorphisms in the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) on the alcohol-related risk of CRC in Caucasian populations. SUBJECTS/METHODS:A...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.173
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Fish intake and the long-chain omega-3 polyunsaturated fatty acids (PUFAs) in fish have been suggested to lower the risk of cognitive decline. We assessed whether serum long-chain omega-3 PUFAs eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) are associated w...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.59
更新日期:2016-08-01 00:00:00
abstract::Glycaemic variability challenges the accuracy and use of the glycaemic index (GI). The purpose of the current study was to determine the role of mastication on GI. Using a randomized, controlled, crossover, non-blind design, 15 healthy young subjects returned on 5 separate days for three glucose and two rice test sess...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2013.231
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Study 1: To establish the validity of scores on Nutrition Screening Tool for Every Preschooler (NutriSTEP), a community-based parent-administered screening tool for assessing nutrition risk, by comparing scores to an expert rating. Study 2: To demonstrate test-retest reliability of NutriSTEP. SUBJECTS/METHO...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602780
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:To examine seasonality of 25-hydroxyvitamin D (25OH-D) levels in British preschool children and the effect of vitamin D supplementation on this. DESIGN:The National Diet and Nutrition Survey of children aged 1.5 4.5 y in Britain during 1992-3 measured dietary intakes and blood status indices, including thos...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600697
更新日期:1999-03-01 00:00:00
abstract::Obesity is a multifactorial and complex affectation that is characterized by a long-term excess energy intake (EI) above energy expenditure (EE). Since fat oxidation seems to be dependent on SNS activation and also seems to remain acutely unaffected by fat intake, this macronutrient is certainly partly responsible for...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1600497
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To know the prevalence of malnutrition and to validate a nutritional screening protocol (SP) in patients hospitalised in Hospitals representative of inpatients admitted for acute illnesses in Galicia. DESIGN:Cross-sectional study of 376 randomised patients (189 female, 210 > or =65 y old) from 12 public hosp...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602157
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:To measure the relative effects of each of four phytosterol ester-enriched low-fat foods (bread, breakfast cereal, milk and yoghurt) on serum lipids, plasma phytosterols and carotenoids. DESIGN:: Three research centres undertook a randomised, incomplete crossover, single-blind study consisting of four treatm...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1038/sj.ejcn.1601837
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Maternal dietary patterns were associated with embryonic growth and congenital anomalies. We aim to evaluate associations between early first trimester maternal dietary patterns and embryonic morphological development among pregnancies with non-malformed outcome. SUBJECTS/METHODS:A total of 228 s...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0161-7
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:It is unknown whether short sleep duration causatively contributes to weight gain. Studies investigating effects of partial sleep deprivation (PSD) on energy balance components report conflicting findings. Our objective was to conduct a systematic review and meta-analysis of human intervention stu...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,meta分析,评审
doi:10.1038/ejcn.2016.201
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVE:To assess vitamin D status in women and their children aged 4-5 years in Northern Jordan during summer. DESIGN:A cross-sectional study in which 93 mother-child dyads volunteered through local community centers between June and July 2007. Anthropometric measurements were performed and information on socioecon...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.99
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:There is a need for objective and universally applicable biomarkers for the intake of foods believed to affect human health. OBJECTIVE:The purpose of this feeding study was to test whether plasma concentrations of carotenoids could be used to distinguish recommended consumption of mixed fruits and vegetable...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601945
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:We investigated the effects of mineral water fortified with folic acid, vitamins B(6), B(12), D and calcium on folate concentrations in serum and erythrocytes, serum vitamin B(12) and plasma homocysteine concentrations in free-living subjects. In addition, we investigated the bioavailability of calcium added ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601795
更新日期:2004-02-01 00:00:00
abstract::Nuclear receptors for retinoids were discovered in 1987 and appeared to belong to the superfamily of steroid/thyroid hormone receptors characterized by a common structure in which the different functions (trans-activation, DNA binding and ligand binding) are present in discrete modular domains in the protein. Retinoid...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract::Despite many methodological difficulties, studies evaluating the relationship between being small for gestational age (SGA) at birth and various measures of adverse neurologic outcome generally show significant associations. Nevertheless, cerebral palsy is rarely found in SGA infants. Minimal neurologic dysfunction is...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:Recent studies have demonstrated beneficial metabolic effects of dietary monounsaturated fatty acids (MUFA) in Type-2 diabetes mellitus (Type-2 DM). The question arises if dietary MUFA also has desirable effects on risk markers in subjects with high risk of developing Type-2 DM. SETTING:University department...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600855
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:To assess how food shortage has been reflected in changes in nutritional status and dietary intake of resident and refugee populations in wartime Sarajevo. DESIGN:Longitudinal observations were carried out on residents (who stayed in their homes) and refugees (living in collective centres). Three out of four...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Anemia, leukopenia and, although less frequently, thrombocytopenia are possible hematological complications of anorexia nervosa considered strictly secondary to chronic malnutrition. This is a retrospective study on the prevalence of these disorders in a large cohort of 318 female patients with AN...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.115
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The overall objective of the European Food Consumption Validation (EFCOVAL) Project was to further develop and validate a trans-European food consumption method to be used for the evaluation of the intake of foods, nutrients and potentially hazardous chemicals within the European population. SUBJ...
journal_title:European journal of clinical nutrition
pub_type: 社论
doi:10.1038/ejcn.2011.82
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Relatively little is known about the influence of chronic oral protein intake on the kidney function. In most studies only the effect of a short-term change in protein intake [6-28 days] or the effect of an acute protein load on the glomerular filtration rate was studied. The purpose of this study was to inve...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Effects of dietary intervention on dietary habits and nutrient levels were studied in 240 women aged 50-65 years who had been operated for a stage I-II breast cancer. Following surgery the women who had participated in a dietary history interview were randomly assigned to one of two groups. The intervention group (n =...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the ability of designer eggs enriched in vitamin E, lutein, selenium (Se) and docosahexaenoic acid (DHA) to deliver micronutrients to the human in a palatable and visually acceptable form. DESIGN:Double-blind, placebo-controlled trial, two treatment groups balanced for sex and age. SETTING:Depar...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600939
更新日期:2000-04-01 00:00:00