Abstract:
:Diet may both increase and decrease oxidative stress in the body. We compared the effects of four strictly controlled isocaloric diets with different intakes of polyunsaturated fatty acids (PUFA, 11 or 3% of energy) and vegetables and fruit (total amount of vegetables and fruit 516 or 1059 g/10 MJ) on markers associated with oxidative stress in 77 healthy volunteers (19-52 years). Plasma protein carbonyls (2-aminoadipic semialdehyde residues) and whole-body DNA and nucleotide oxidation (urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion) tended to decrease in all treatment groups with no differences between the diets. The diets did not differ in their effects on red blood cell antioxidative enzyme activities, either. The results suggest that in healthy volunteers with adequate nutrient intakes, 6-week diets differing markedly in the amount of PUFA or vegetables and fruit do not differ in their effects on markers associated with oxidative stress.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Freese R,Dragsted LO,Loft S,Mutanen Mdoi
10.1038/sj.ejcn.1602865subject
Has Abstractpub_date
2008-09-01 00:00:00pages
1151-3issue
9eissn
0954-3007issn
1476-5640pii
1602865journal_volume
62pub_type
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journal_title:European journal of clinical nutrition
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journal_title:European journal of clinical nutrition
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更新日期:2007-04-01 00:00:00
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journal_title:European journal of clinical nutrition
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更新日期:2005-08-01 00:00:00
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更新日期:2008-06-01 00:00:00
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更新日期:2002-11-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-01-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
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更新日期:2018-09-01 00:00:00
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doi:10.1038/sj.ejcn.1602275
更新日期:2006-01-01 00:00:00