Selenium intake reduces serum C3, an early marker of metabolic syndrome manifestations, in healthy young adults.

Abstract:

OBJECTIVES:To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations. METHODS:This study enrolled 100 healthy young adults aged 18-34 years. Anthropometric and blood pressure measurements and lifestyle features were analyzed. Fasting blood samples were collected for the measurement of glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol, triacylglycerols and C3 concentrations. Nail samples were collected for the analysis of selenium concentrations. RESULTS:Values of BMI (P=0.034), sum of skinfold thicknesses (STs) (P=0.021), body fat mass (BFM) (P=0.023), percentage of overweight subjects (P=0.007), serum triacylglycerols (P=0.012) and nail selenium (P=0.001) were significantly different between subjects above and below the median of serum C3 concentrations. The following correlations with serum C3 were identified tricipital ST (P=0.033), sum of STs (P=0.012), BMI (P=0.008), BFM (P=0.018), waist-to-height ratio (P=0.016), serum glucose (P=0.045), serum triacylglycerols (P=0.001) and nail selenium (P=0.006). Circulating C3 showed a positive association with several adiposity markers such as BMI (P=0.001), waist circumference (P=0.006), waist-to-height ratio (P=0.002), BFM (P=0.025), as well as serum glucose (P=0.027) and triacylglycerols (P<0.001), whereas nail selenium was a statistically significant negative predictor of C3 concentrations (P=0.018). CONCLUSIONS:C3 seems to be related with selenium status and several anthropometrical and biochemical measurements linked to metabolic syndrome in apparently healthy young adults. These findings suggest a possible role for selenium intake in the modulation of C3, whose assessment may be an early marker of metabolic syndrome manifestations.

journal_name

Eur J Clin Nutr

authors

Puchau B,Zulet MA,González de Echávarri A,Navarro-Blasco I,Martínez JA

doi

10.1038/ejcn.2008.48

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

858-64

issue

7

eissn

0954-3007

issn

1476-5640

pii

ejcn200848

journal_volume

63

pub_type

杂志文章
  • Complex interactions with infection and diet may explain seasonal growth responses to vitamin A in preschool aged Indonesian children.

    abstract:OBJECTIVE:To explore the potential contribution of respiratory infections and vitamin A intakes to the seasonal effect of vitamin A supplementation on child growth. METHODS:Data from a randomized double-blind placebo-controlled trial, in which a single high dose of vitamin A or placebo was given every 4 months to 1405...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1038/sj.ejcn.1601920

    authors: Hadi H,Dibley MJ,West KP Jr

    更新日期:2004-07-01 00:00:00

  • Energy expenditure and substrate oxidation in White and African American young adults without obesity.

    abstract::It has been hypothesized that the increased risk of obesity among African Americans may be partially explained by low energy expenditure (EE) and impaired fat oxidation. Twelve White adults without obesity were pair-matched by age, sex and body mass index (BMI) to a sample of 12 African Americans. Resting EE (REE), 24...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/s41430-018-0202-2

    authors: Katzmarzyk PT,Most J,Redman LM,Rood J,Ravussin E

    更新日期:2018-06-01 00:00:00

  • Validity and reproducibility of self-reported intake of fruit and vegetable among 6th graders.

    abstract:OBJECTIVE:Reproducible and valid methods for measuring fruit and vegetable consumption among young school children are urgently needed. The aim of this study was to test the reproducibility and the validity of a newly developed questionnaire on the intake of fruit and vegetable among Norwegian 6th graders. The question...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601875

    authors: Andersen LF,Bere E,Kolbjornsen N,Klepp KI

    更新日期:2004-05-01 00:00:00

  • A study of protein turnover in preterm neonates using 15N enrichment of urinary ammonia.

    abstract::Hydrolysed yeast protein labelled with 15N was used to measure protein turnover, protein synthesis and protein breakdown in preterm infants. The yeast tracer was given as a bolus intragastric dose and protein turnover was determined from the 15N enrichment of urinary ammonia over known periods of about 12 h. Six boys ...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Stack T,Reeds P,Preston T,Hay S,Lloyd DJ,Aggett PJ

    更新日期:1990-03-01 00:00:00

  • School food policy at primary and secondary schools in Belgium-Flanders: does it influence young people's food habits?

    abstract:OBJECTIVE:To describe the availability of food items at primary and secondary schools in Belgium-Flanders and to examine the influence of school food policy (availability of food items, school food rules, nutrition education programmes) and aggregated school socioeconomical status (AGG SES) on the consumption of fruit,...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602068

    authors: Vereecken CA,Bobelijn K,Maes L

    更新日期:2005-02-01 00:00:00

  • Relationship between alcohol intake, health and social status and cardiovascular risk factors in the Urban Paris-Ile-de-France Cohort: is the cardioprotective action of alcohol a myth?

    abstract:BACKGROUND/OBJECTIVES:Observational studies document the inverse relationship between cardiovascular disease (CVD) and moderate alcohol intake. However, the causal role for alcohol in cardioprotection remains uncertain as such protection may be caused by confounders and misclassification. The aim of our study was to ev...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2010.61

    authors: Hansel B,Thomas F,Pannier B,Bean K,Kontush A,Chapman MJ,Guize L,Bruckert E

    更新日期:2010-06-01 00:00:00

  • Virtual food components: functional food effects expressed as food components.

    abstract:BACKGROUND:The ability to communicate food benefits is essential for the successful development of functional foods and their role in improving public health. However, the functional efficacy of foods often cannot be represented by food composition. The concept of virtual food components (VFCs)-food data that express h...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601769

    authors: Monro JA

    更新日期:2004-02-01 00:00:00

  • The association of education with long-term weight change in the EPIC-PANACEA cohort.

    abstract:BACKGROUND/OBJECTIVES:Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in t...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2012.55

    authors: Rohrmann S,Steinbrecher A,Linseisen J,Hermann S,May A,Luan J,Ekelund U,Overvad K,Tjønneland A,Halkjær J,Fagherazzi G,Boutron-Ruault MC,Clavel-Chapelon F,Agnoli C,Tumino R,Masala G,Mattiello A,Ricceri F,Travier N,Ami

    更新日期:2012-08-01 00:00:00

  • Effects of nutritional support on the clinical outcomes of well-nourished patients with cancer: a meta-analysis.

    abstract::The effects of nutritional support on well-nourished patients have been investigated, but the results were inconsistent among different articles. We performed the meta-analysis to examine the existing evidence. We systematically retrieved articles from PubMed, Web of Science and the Cochrane Library to identify the ev...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,评审

    doi:10.1038/s41430-020-0595-6

    authors: Zhang X,Chen X,Yang J,Hu Y,Li K

    更新日期:2020-10-01 00:00:00

  • Daily energy expenditure, activity patterns, and energy costs of the various activities in French 12-16-y-old adolescents in free living conditions.

    abstract:BACKGROUND:Changes in lifestyle and increases in sedentary activities during recent decades have been shown to contribute to the prevalence of overweight in adolescents. OBJECTIVES:To determine the inter-individual variability and the day-to-day variations in daily energy expenditure (DEE) and activity pattern, and th...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601395

    authors: Vermorel M,Vernet J,Bitar A,Fellmann N,Coudert J

    更新日期:2002-09-01 00:00:00

  • Feeding practice among younger Tibetan children living at high altitudes.

    abstract:OBJECTIVE:Few published data are available on the feeding practice of younger children in Tibet. Our study investigated feeding pattern of younger Tibetan children. DESIGN AND SUBJECTS:The study was a cross-sectional survey conducted in Tibet. A sample of 1655 children younger than 36 months old and their mothers was ...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602207

    authors: Dang S,Yan H,Yamamoto S,Wang X,Zeng L

    更新日期:2005-09-01 00:00:00

  • A study of Hassawi rice (Oryza sativa L.) in terms of its carbohydrate hydrolysis (in vitro) and glycaemic and insulinaemic indices (in vivo).

    abstract:BACKGROUND/OBJECTIVES:A high prevalence of Type 2 diabetes exists in Saudi Arabia. Epidemiological evidence suggests that low glycaemic index (GI) diets reduce diabetes risk. Yet, little is known about the GI of traditional Saudi Arabian staples such as Hassawi rice (HR). HR was evaluated in terms of its GI and insulin...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/ejcn.2011.4

    authors: Al-Mssallem MQ,Hampton SM,Frost GS,Brown JE

    更新日期:2011-05-01 00:00:00

  • Towards NACNE: improving eating habits in a Scottish health board.

    abstract::A low-cost locally based nutrition education programme was designed around the employment of a part-time dietitian with the aim of improving the nutritional intakes of Grampian Health Board staff. Its effectiveness was evaluated by assessment of habitual dietary intakes of staff, using a previously validated questionn...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Lean ME,Anderson AS,Coubrough HA

    更新日期:1988-02-01 00:00:00

  • The Mediterranean diet in Spain.

    abstract::The purpose of this paper is to assess the food habits of the Spanish population and the composition of the fat consumed. The national food survey data have been used. This survey was carried out during one week in a representative sample of households by means of recorded weighing or the household measures method. Th...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Moreiras-Varela O

    更新日期:1989-01-01 00:00:00

  • Predictive equations for basal metabolic rates of Indian males.

    abstract::The article deals with the generation of a prediction equation for basal metabolic rate (BMR) of well-nourished Indian males, from prospective measurements on 121 males, using a single validated technique. The equation related BMR to simple measures such as weight (WT) and age, and was given by: BMR (kJ/d) = 48.7 * WT...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,评审

    doi:

    authors: Soares MJ,Francis DG,Shetty PS

    更新日期:1993-06-01 00:00:00

  • Celiac disease and obesity: need for nutritional follow-up after diagnosis.

    abstract::More than 20 years of serological approach to diagnosis of celiac disease (CD) has deeply changed the classical clinical presentation of the disease, and some reports indicate that CD and obesity can coexist in both childhood and adolescence. We reviewed clinical records of 149 children with CD followed in our institu...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2010.161

    authors: Valletta E,Fornaro M,Cipolli M,Conte S,Bissolo F,Danchielli C

    更新日期:2010-11-01 00:00:00

  • Effects of long-term excessive iodine intake on blood lipids in Chinese adults: a cross-sectional study.

    abstract:OBJECTIVE:The aim of this study was to evaluate the effects of long-term excessive iodine intake on blood lipids in adults. METHODS:Three counties from Dezhou city and Liaocheng city in the Shandong province of China were selected as survey locations. Three to five villages were selected from each county and then cate...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/s41430-020-00773-6

    authors: Gao J,Zhang M,Wang X,Wang M,Zhang B,Jiang W,Bian J,Liu X

    更新日期:2020-10-11 00:00:00

  • Serum docosahexaenoic and eicosapentaenoic acid and risk of cognitive decline over 10 years among elderly Japanese.

    abstract:BACKGROUND/OBJECTIVES:To clarify the association of serum docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) levels with cognitive decline over 10 years. SUBJECTS/METHODS:This study was part of the National Institute for Longevity Sciences - Longitudinal Study of Aging, and was conducted with 232 male and 198 ...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2013.264

    authors: Otsuka R,Tange C,Nishita Y,Kato Y,Imai T,Ando F,Shimokata H

    更新日期:2014-04-01 00:00:00

  • Effect of vitamin C on common cold: randomized controlled trial.

    abstract:OBJECTIVE:To investigate the relationship between the common cold and vitamin C supplementation. DESIGN:A double-blind, 5-year randomized controlled trial. SETTING:A village in Akita prefecture, one of the regions in Japan with the highest mortality from gastric cancer. SUBJECTS:Participants in annual screening prog...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/sj.ejcn.1602261

    authors: Sasazuki S,Sasaki S,Tsubono Y,Okubo S,Hayashi M,Tsugane S

    更新日期:2006-01-01 00:00:00

  • Effects of cod liver oil on lipids and platelets in males and females.

    abstract::Thirty-four healthy non-smoking subjects (20 men and 14 women) were given 25 ml cod liver oil (CLO) daily as dietary supplement for 8 weeks in a controlled cross-over study. Prior to intervention, women had significantly higher serum total (P < 0.05) and high density lipoprotein (HDL) (P < 0.001) cholesterol values, h...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章

    doi:

    authors: Hansen JB,Berge LN,Svensson B,Lyngmo V,Nordøy A

    更新日期:1993-02-01 00:00:00

  • Moderate alcohol consumption reduces plasma C-reactive protein and fibrinogen levels; a randomized, diet-controlled intervention study.

    abstract:OBJECTIVE:To evaluate the effect of moderate alcohol consumption on the acute phase proteins C-reactive protein and fibrinogen. DESIGN:Randomized, diet-controlled, cross-over study. SETTING:The study was performed at TNO Nutrition and Food Research, Zeist, The Netherlands. SUBJECTS:Ten middle-aged men and 10 postmen...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1038/sj.ejcn.1601459

    authors: Sierksma A,van der Gaag MS,Kluft C,Hendriks HF

    更新日期:2002-11-01 00:00:00

  • Nuclear retinoid receptors: mediators of retinoid effects.

    abstract::Nuclear receptors for retinoids were discovered in 1987 and appeared to belong to the superfamily of steroid/thyroid hormone receptors characterized by a common structure in which the different functions (trans-activation, DNA binding and ligand binding) are present in discrete modular domains in the protein. Retinoid...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,评审

    doi:

    authors: van der Saag PT

    更新日期:1996-07-01 00:00:00

  • Parental IQ and cognitive development of malnourished Indonesian children.

    abstract::A cross-sectional study of children in West Kalimantan, Indonesia, was conducted to examine the relationship between malnutrition history, child IQ, school attendance, socioeconomic status, parental education and parental IQ. In unadjusted analyses, severely stunted children had significantly lower IQ scores than mild...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602103

    authors: Webb KE,Horton NJ,Katz DL

    更新日期:2005-04-01 00:00:00

  • Towards a CEN Standard on food data.

    abstract:BACKGROUND/OBJECTIVES:A major goal of the European Food Information Resource (EuroFIR) Network of Excellence is to provide tools to overcome existing differences among member states and parties with respect to documentation and interchange of food composition data. Establishment of a common CEN (Comité Européen de Norm...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2010.210

    authors: Becker W,CEN\/TC387 Food Data.

    更新日期:2010-11-01 00:00:00

  • Anthropometric reference data for elderly Swedes and its disease-related pattern.

    abstract:BACKGROUND/OBJECTIVES:Anthropometric measurement is a noninvasive and cost-efficient method for nutritional assessment. The study aims to present age- and gender-specific anthropometric reference data for Swedish elderly in relation to common medical conditions, and also formulate prediction equations for such anthropo...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2015.73

    authors: Gavriilidou NN,Pihlsgård M,Elmståhl S

    更新日期:2015-09-01 00:00:00

  • The effect of dietary trans alpha-linolenic acid on plasma lipids and platelet fatty acid composition: the TransLinE study.

    abstract:OBJECTIVE:To collect (i) baseline data and (ii) execute a large multicentre study examining the effect of trans alpha-linolenic acid on its incorporation into plasma lipids and on risk factors for coronary heart disease. DESIGN:Male volunteers were recruited and the habitual diet assessed by a 4-d weighed record. Fatt...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1038/sj.ejcn.1600903

    authors: Sébédio JL,Vermunt SH,Chardigny JM,Beaufrère B,Mensink RP,Armstrong RA,Christie WW,Niemelä J,Hénon G,Riemersma RA

    更新日期:2000-02-01 00:00:00

  • Food preferences and aversions and dietary pattern in anorexia nervosa patients.

    abstract::Food intake, meal frequency and occurrence of vomiting and purging were assessed in 20 female patients with anorexia nervosa (AN) by two dietitians by means of a dietary history over the past month. Ten lean healthy women and 10 of normal weight served as two groups of controls. Two self-administered questionnaires, c...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Van Binsbergen CJ,Hulshof KF,Wedel M,Odink J,Coelingh Bennink HJ

    更新日期:1988-08-01 00:00:00

  • Adherence to the Dutch dietary guidelines is inversely associated with 20-year mortality in a large prospective cohort study.

    abstract:BACKGROUND/OBJECTIVES:The Dutch guidelines for a healthy diet aim to reduce major chronic diseases. However, supporting evidence on their overall association with all-cause and cause-specific mortality is limited. Recently, the Dutch Healthy Diet-index (DHD-index) has been developed to assess adherence to these guideli...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2015.163

    authors: van Lee L,Geelen A,Kiefte-de Jong JC,Witteman JC,Hofman A,Vonk N,Jankovic N,Hooft van Huysduynen EJ,de Vries JH,van 't Veer P,Franco OH,Feskens EJ

    更新日期:2016-02-01 00:00:00

  • Effect of multiple micronutrient-fortified food on mild morbidity and clinical symptoms in Zambian infants: results from a randomised controlled trial.

    abstract:BACKGROUND/OBJECTIVES:We aimed to assess the effects on mild morbidity of a richly micronutrient-fortified complementary/replacement food given to Zambian infants aged 6-18 months. Previous results (The Chilenje Infant Growth, Nutrition and Infection Study Team, 2010) showed an increase in the rate of hospital referral...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/ejcn.2011.103

    authors: Manno D,Siame J,Larke N,Baisley K,Kasonka L,Filteau S

    更新日期:2011-10-01 00:00:00

  • Iodine deficiency alone cannot account for goitre prevalence among pregnant women in Modhupur, Bangladesh.

    abstract:OBJECTIVE:We wished to determine the contributing causes of goitre among pregnant women in rural Bangladesh to provide baseline data before instituting iodine supplementation. DESIGN:All pregnant women in a subdistrict of Modhupur, Bangladesh were assessed for goitre size and were asked to give blood and urine samples...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Filteau SM,Sullivan KR,Anwar US,Anwar ZR,Tomkins AM

    更新日期:1994-04-01 00:00:00