Abstract：
OBJECTIVE:To examine the effect of low-dose fish oil supplementation on specific growth factors, purported to play a central role in lesion formation, and also on the total growth factor activity of serum, as assessed by the induction of DNA synthesis in cultured human arterial smooth muscle cells. DESIGN:Randomized placebo-controlled double-blind intervention study. SETTING:Free-living population. SUBJECTS:Sixty-three healthy volunteers, 37 males and 26 females. INTERVENTIONS:Four treatment regimes with subjects receiving 0, 0.3,0.6 or 0.9 g/day of n-3 PUFA for an 8 week period. Blood samples were taken at baseline and following the 8 week intervention. All samples were analysed in batch following completion of the study. RESULTS:Consumption of fish oil had no effect on serum platelet-derived growth factor (PDGF), or transforming growth factor beta (TGFbeta) concentration. Furthermore, fish oil supplementation did not alter the total growth factor activity of serum. CONCLUSIONS:Results indicate that low-dose fish oil supplementation, equivalent to about two portions of fatty fish per week and providing less than 1 g n-3 PUFA/day, does not alter the levels of the major serum growth factors and does not modify total serum growth factor activity in healthy human volunteers. SPONSORSHIP:European Union shared cost project (FAIR-CT-95-0085).
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Wallace JM,McCabe AJ,Roche HM,Higgins S,Robson PJ,Gilmore WS,McGlynn H,Strain JJdoi
10.1038/sj.ejcn.1601076subject
Has Abstractpub_date
2000-09-01 00:00:00pages
690-4issue
9eissn
0954-3007issn
1476-5640journal_volume
54pub_type
临床试验,杂志文章,随机对照试验abstract：OBJECTIVE:The purpose of the present study was to compare the nutrient intake and the nutritional status between German middle-class alcohol consumers and non-drinkers. DESIGN:Cross-sectional study using patients with different stages of alcoholic liver disease (ALD) and healthy volunteers. SETTING:Southern Germany. ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601557
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:To determine dose-dependent relationship between ingested fat and its oxidation in the immediate post-prandial period in humans. DESIGN:Subjects were randomly selected for the study at the Dunn Clinical Nutrition Centre, Cambridge, UK. Subjects ingested naturally enriched 13C corn-oil doses (range 20-140g) i...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601112
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:To determine current practice in the delivery of parenteral nutrition (PN) in Australian hospitals. DESIGN:A cross-sectional mail survey. SETTING:Acute-care adult hospitals with greater than 200 beds in Australia. SUBJECTS:A total of 67 hospitals (65.7% response rate). INTERVENTION:Surveys were posted to ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602547
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Disruptions in redox balance lead to oxidative stress, a promoter of morbidity in critical illness. This study aimed to: (1) characterize the plasma and alveolar thiol/disulfide redox pools, (2) examine their associations with alveolar macrophage phagocytosis, and (3) determine the effect of high ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41430-017-0047-0
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:The EURRECA (EURopean micronutrient RECommendations Aligned) Network of Excellence collated current micronutrient recommendations. A user-friendly tool, Nutri-RecQuest, was developed to allow access to the collated data and to create a database source for use in other nutritional software tools. METHODS:Rec...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.60
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:This study is aimed at investigating the influence of body size, body fat and sexual maturation on blood pressure (BP) in adolescents. DESIGN:A cross-sectional study. SETTING:A suburban student population of Southern Italy. SUBJECTS:One hundred ninety students attending the first and second year of a secon...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600731
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVES:To assess the influence of a low-fat, low-energy diet on the intake of vitamins and minerals in patients with overweight and hyperlipidemia. SETTING:Outpatient clinic for hyperlipidemia treatment. SUBJECTS:A total of 134 subjects chosen from patients attending Outpatient Clinic of Metabolic Diseases. INTE...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601467
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVE:To evaluate glycaemic and insulinaemic index and in vitro digestibility of the five most common Cameroonian mixed meals consisting of rice+tomato soup (diet A), bean stew+plantains (B), foofoo corn+ndolé (C), yams+groundnut soup (D), and koki beans+cassava (E). SUBJECTS:Ten healthy non-obese volunteers, aged...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601592
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:To determine whether the age-related decrease in resting energy expenditure (REE) is explained by variations in body composition. DESIGN:In Study 1, adult subjects (20-70 years) from the Quebec Family Study were classified into five different age groups. Body composition was measured by hydrodensitometry to ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602262
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:To assess the bioavailability of vitamins A and E administered parenterally with either water-soluble or lipid-soluble preparations. STUDY DESIGN:A water soluble preparation (MVI Pediatric) administered with a glucose-amino acid solution and a lipid soluble preparation (Vitalipid N Infant) infused with a lip...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601417
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2012.55
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To assess the suitability of the body mass index (BMI) as an indicator of standard of living in developing countries. DESIGN, SETTING AND SUBJECTS:The analysis is based on data collected in the first two rounds of the Ghana Living Standards Survey, held in 1987/88 (GLSS-I) and 1988/89 (GLSS-II). The dataset ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600528
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:The hypothesis was tested that the rate of postmenopausal bone loss is inversely associated with long-term urinary excretion of phyto-oestrogens, as a marker of habitual dietary intake. DESIGN:Secondary analysis of a 10-year follow-up study (1979 1989) among postmenopausal women in the Netherlands. SUBJECTS...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600659
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:To determine the effect on blood pressure of dietary advice to consume a combination of plant-based cholesterol-lowering foods (dietary portfolio). METHODS:For 1 year, 66 hyperlipidemic subjects were prescribed diets high in plant sterols (1.0 g/1000 kcal), soy protein (22.5 g/1000 kcal), viscous fibers (10 ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602768
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To explore whether mothers' lifetime experiences with their own weight status and related cognitive and affective factors influence child feeding behavior. SUBJECTS/METHODS:Overweight mothers (N = 221) of 4-5 year olds recalled their weight at four time points, and were grouped into weight histor...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-017-0071-0
更新日期：2018-11-01 00:00:00
abstract：:Bioelectrical impedance analysis is an extremely popular method for assessment of body composition. Despite its wide-spread use over the past thirty years, its accuracy and clinical value is still questioned. Most frequently, criticisms focus on its purported poor absolute accuracy and that different impedance analyse...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/s41430-018-0335-3
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVES:The acute phase response (APR) influences indicators of iron status. A recent WHO/CDC consultation recommended concurrent measurement of alpha-1-acid-glycoprotein (AGP) in surveys to control for the APR, and aid in interpreting iron status. They proposed further exploratory analyses using AGP. We examined wh...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2008.33
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVES:To estimate the energy cost of resting (RMR), sitting and standing for urban Indian adults and compare these estimates with the reported values. DESIGN:Energy costs were measured using oxylog while body fat was estimated using equipment (HBF300, OMRON Corporation, Japan) that works on the principle of bioel...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601211
更新日期：2001-08-01 00:00:00
abstract：OBJECTIVES:To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations. METHODS:This study enrolled 100 healthy young adults aged 18-34 years. Ant...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2008.48
更新日期：2009-07-01 00:00:00
abstract：:To study the role of diet, 197 patients of essential hypertension were randomized to either experimental diet (group A, 97 cases) or normal diet (group B, 100 cases) with diuretics given to both the groups. The age varied between 25 and 65 years and 154 were males. The study diet included a significantly higher conten...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1990-04-01 00:00:00
abstract：OBJECTIVES:To describe the intake of vitamins thiamine (B1), riboflavin (B2), B6 (pyridoxine), B12 (cobalamine) and C (ascorbic acid) and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. METHODS:Between 1995 and 2000, 36...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.78
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Food composition data (FCD) can provide important information in relation to diet and health; therefore, data on food composition have broad applications in health care. The objective of this study was to provide an overview of added-value eHealth systems that use modern information and communicat...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.222
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:To determine the prevalence of biochemical iron deficiency and identify factors associated with ferritin levels among 6-24-month-old urban South Island New Zealand children. DESIGN:Cross-sectional survey conducted from May 1998 to March 1999. SETTING:The cities of Christchurch, Dunedin and Invercargill. S...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601751
更新日期：2004-01-01 00:00:00
abstract：:This corrects the article DOI: 10.1038/ejcn.2017.20. ...
journal_title：European journal of clinical nutrition
pub_type： 已发布勘误
doi：10.1038/ejcn.2017.96
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:The efficacy of zinc combined with vitamin A or multiple micronutrients in preventing diarrhoea is unclear in African countries with high prevalence of human immunodeficiency virus (HIV)-exposed children. Potential modifying factors, such as stunting, need to be addressed. The objective of this stu...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/ejcn.2008.78
更新日期：2009-07-01 00:00:00
abstract：:Serum lipid levels are considered to be one of the main risk factors for cardiovascular diseases in middle-aged men and women. The significance, however, of serum lipid metabolism as a cardiovascular disease risk factor in the elderly has yet to be clarified. This paper focuses upon the serum lipid levels of groups of...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：OBJECTIVES:The content of n-3 (omega-3) polyunsaturated fatty acids in fat tissue is a valid indicator of their long-term consumption. We studied the stability of n-3 fatty acids in human subcutaneous fat microbiopsies after 6 and 11 y of storage. DESIGN:Microbiopsies were taken from a lump of human adipose tissue and...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601614
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:It is hypothesised that epigenetic mechanisms including DNA methylation may underlie the relationship between early-life nutrition and child cognitive outcomes. This study aimed to identify dietary patterns associated with the intake of one-carbon metabolism nutrients in children aged 2-3 years. METHODS:A v...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0376-7
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to compare red blood cell (RBC) fatty acid composition, plasma lipids and lipoproteins and dietary intake between urban and rural Melanesian Fijians. DESIGN:A cross-sectional study was performed in a random subsample (n = 154) from a total survey population of 589 subjects. SETTING:...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To determine which component of the metabolic syndrome (MetS) is the best predictor of its development. SUBJECTS/METHODS:In this cohort study, 2279 subjects aged 20-87 years without MetS selected from among the participants of the cross-sectional phase of the Tehran Lipid and Glucose Study (TLGS)...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.111
更新日期：2010-10-01 00:00:00
