Abstract：
OBJECTIVE:To determine whether the age-related decrease in resting energy expenditure (REE) is explained by variations in body composition. DESIGN:In Study 1, adult subjects (20-70 years) from the Quebec Family Study were classified into five different age groups. Body composition was measured by hydrodensitometry to determine fat mass and fat-free mass as predictors of REE. In the youngest group of individuals these predictors were used to plot a reference regression that was then used to predict REE in the other age groups. In Study 2, this issue was investigated in a longitudinal design (6-year follow-up). Subjects were subdivided into three groups and a reference regression was plotted at the beginning of the follow-up and was then used to predict REE 6 years later in the three age groups. SUBJECTS:In Study 1, 627 adults (288 men and 339 women), aged between 20 and 70 years. In Study 2, 191 adults (93 men and 98 women). RESULTS:In Study 1, measured REE was 329, 302, 528 and 636 kJ/day (P < 0.0001) below predicted REE at 34, 44, 54 and 64 years, respectively. In Study 2 the most marked deviation from predicted REE in response to the 6-year follow-up in men was observed in young adults (-548 kJ/day, P < 0.001) while in women, the largest deviation occurred later in life (-720 kj/day, P < 0.001). CONCLUSION:Aging is accompanied by a decrease in REE that is significantly greater than what is predicted by variations in body composition. This decrease may reach a mean level of about 500-800 kj/day.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Alfonzo-González G,Doucet E,Bouchard C,Tremblay Adoi
10.1038/sj.ejcn.1602262subject
Has Abstractpub_date
2006-01-01 00:00:00pages
18-24issue
1eissn
0954-3007issn
1476-5640pii
1602262journal_volume
60pub_type
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journal_title：European journal of clinical nutrition
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