Abstract:
:To study the role of diet, 197 patients of essential hypertension were randomized to either experimental diet (group A, 97 cases) or normal diet (group B, 100 cases) with diuretics given to both the groups. The age varied between 25 and 65 years and 154 were males. The study diet included a significantly higher content of potassium (K), magnesium (Mg), calcium (Ca), polyunsaturated fat, and complex carbohydrates compared to the normal diet. At entry to the study, age, sex, risk factors, mean blood pressures, mean serum Mg, K, Ca, and Na, and drug therapy were comparable in both groups. After 1 year of follow-up, there were significantly fewer patients with resistant hypertension in group A (5) than in group B (17). Mean systolic (148.22 +/- 10.1 mm Hg) and diastolic (90.2 +/- 4.84 mm Hg) pressures in group A were lowered compared to mean systolic (160 +/- 12.0 mm Hg) and diastolic (103.3 +/- 5.8 mm Hg) pressures in group B and initial mean systolic (152.2 +/- 12.8 mm Hg) and diastolic (99.8 +/- 7.2 mm Hg) pressures. Mean serum magnesium (1.86 +/- 9.22 mEq/l) and potassium (4.86 +/- 0.39 mEq/l) levels in group A were significantly higher compared to mean levels of 1.56 +/- 0.11 and 4.0 +/- 0.29 mEq/l, respectively, in group B. However compared to initial levels, K and Mg showed no significant changes in groups A and B. There was a significantly lower incidence of complications in group A (58) compared to group B (100). It is possible that a diet low in Na/K ratio and rich in complex carbohydrates, polyunsaturates, K and Mg may cause a significant reduction in blood pressure and its complications.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Singh RB,Sircar AR,Rastogi SS,Singh Rsubject
Has Abstractpub_date
1990-04-01 00:00:00pages
319-27issue
4eissn
0954-3007issn
1476-5640journal_volume
44pub_type
临床试验,杂志文章,随机对照试验abstract::Efforts to combat nutrient deficiencies have centered on supplemental nutrient administration and addition of selected nutrients to the food chain in the form of food fortification. Over the past several decades, and as the association between diet and chronic diseases became apparent, supplementation and fortificatio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601803
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Protein substitutes (PS) are an essential component in the dietary management of phenylketonuria (PKU). PS are available as phenylalanine-free amino-acid mixtures (AAM), glycomacropeptide-based PS (GMP) and large neutral amino acids (LNAA). There is a lack of information regarding their availabili...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.54
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess how the glycaemic potency (blood glucose (BG)-raising potential) of breakfast is associated with cognitive function (CF) in school children, taking into account important confounders, including iron status, underlying physiological adaptations and socio-economic status. M...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.96
更新日期:2010-09-01 00:00:00
abstract::Adverse reaction to cow's milk and infant formulas are common during infancy. Cow's milk has more than 20 constituents proteins and in principle many are capable of giving rise to an IgE mediated response. The prevalence of cow's milk allergy is between 0.5-10% of the paediatric population (Frier & Kletter, 1970, Gerr...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::As part of the Euronut SENECA study, food consumption has been assessed in 1217 men and 1241 women, born between 1913 and 1918 and living in 18 towns in 12 European countries. The method used was a standardized modified dietary history, including a 3-day estimated record and a food frequency list based on local food p...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of intensive lifestyle education on dietary practices, exercise and metabolic measurements in people with insulin-dependent diabetes mellitus (IDDM). DESIGN:Sixty-one volunteer subjects with IDDM were randomised to intensive (Group 1) or standard (Group 2) education programmes for s...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600478
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Few studies in Latin American paediatric populations have differentiated fat deposits in specific areas, such as intra-abdominal fat (IAF) and subcutaneous abdominal fat (SAF). Research in diverse populations is needed, as patterns of fat accumulation vary by ethnicity. The aim of this study was to...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2017.28
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Consumption of fruit and vegetables (F&V) is associated with a lower cardiovascular disease (CVD) risk. Smoking may affect the strength of this association. The objective of this study was to compare the relationship between the frequency of F&V intake and CVD risk in male current, former and neve...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.46
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To study the relation between indicators of infection and Schistosoma mansoni and S. haematobium infection, and serum concentrations of zinc, ferritin and retinol. DESIGN:Cross-sectional. SETTING AND SUBJECTS:313 rural Zimbabwean schoolchildren (144 boys and 169 girls, 11-17 years). VARIABLES:S. mansoni an...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:To study whether a free supply of vitamin D(2) drops to 6-week-old infants together with tailor-made information handouts improves the vitamin D status after 7 weeks in the intervention group compared to a control group. SUBJECTS/METHODS:In this cluster randomized controlled trial in eight child h...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602982
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:In spite of several studies relating dietary patterns to breast cancer risk, evidence so far remains inconsistent. This study aimed to investigate associations of dietary patterns derived with three different methods with breast cancer risk. SUBJECTS/METHODS:The Mediterranean Diet Score (MDS), pr...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2014.135
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To validate bio-electric impedance spectroscopy (BIS) by comparison with other methods for determination of body water compartments in stable subjects with an ileostomy and no or minor small bowel resection for inflammatory bowel disease (IBD). SUBJECTS:Twenty-one subjects were included, age range 36-65 y (f...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601378
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The aim of this study was to evaluate the association of serum 25-hydroxyvitamin D (25(OH)D) with disability and frequency of relapses in relapsing-remitting multiple sclerosis (MS) patients. SUBJECTS/METHODS:The study included 184 patients with relapsing-remitting MS who were receiving immune-mo...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.51
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is a high prevalence of diabetes mellitus associated with insulin resistance in Indian adults, probably due to an inappropriately high accumulation of body fat at lower body mass indices (BMIs, kg/m(2)), as well as to a lower skeletal muscle mass. Although skeletal muscle is an important sit...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.32
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To evaluate in 14 healthy volunteers the gastrointestinal tolerance to an indigestible bulking sweetener containing fructo-oligosaccharides (FOS). DESIGN:In order to mimic their usual pattern of consumption, FOS were ingested throughout the day either occasionally (once a week, first period) or regularly (ev...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The hallmark of cystic fibrosis (CF) is chronic lung inflammation. The severity of lung disease is closely correlated with immunoglobulin G (IgG) levels. Beyond its contribution to the bone health, the importance of vitamin D has not been fully recognized owing to the lack of human studies providi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2010.194
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Previous small studies have shown either no difference or a lower risk of symptomatic gallstone disease in vegetarians than in non-vegetarians. This study examined the incidence of symptomatic gallstone disease in a cohort of British vegetarians and non-vegetarians, and investigated the associatio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.252
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Famine exposure is a potential risk factor for adverse cardiometabolic health. However, the relationship between famine exposure during early life and carotid plaque in adulthood remains unclear. Therefore, the aim was to investigate the relationship between famine exposure during early life and the risks fo...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00756-7
更新日期:2020-09-16 00:00:00
abstract:OBJECTIVE:To examine the relationship between selenium nutritional status and intermediates of human immunodeficiency virus (HIV)-1 transmission. DESIGN:Prospective cohort study. SETTING:A study clinic at Muhimbili National Hospital, Dar es Salaam, Tanzania. SUBJECTS:A total of 340 HIV-1-infected pregnant women with...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602567
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:It was determined whether a combination of Lactobacillus acidophilus (L. acidophilus) 74-2 and Bifidobacterium animalis subsp lactis DGCC 420 (B. lactis 420) affect the faecal microbiota as well as immunological parameters and blood lipids in healthy adults. DESIGN:A placebo-controlled, double-blinded, rando...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602761
更新日期:2008-05-01 00:00:00
abstract::We previously detected that ~50% of kidney transplant patients (KTPs) present sarcopenia using the first European Working Group on Sarcopenia in Older People (EWGSOP1) consensus. Our aim was to evaluate the agreement between the sarcopenia diagnosis using EWGSOP1 and the new consensus (EWGSOP2) in KTPs. A cross-sectio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-019-0535-5
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between weight gain, changes in body composition and physiological characteristics of fitness during the recovery from anorexia nervosa. DESIGN:Longitudinal over eight weeks of intensive inpatient re-feeding (Wk 0-8). SETTING:The London Hospital Medical College. SUBJECTS:Ten fem...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVES:To examine the frequency of street food consumption of people living in low-income settlements in Nairobi and the role of street foods in their daily diet and to reveal why people consume street foods rather than home-prepared foods. SETTING, SUBJECTS AND METHODS: A cross-sectional descriptive study was done...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601183
更新日期:2001-07-01 00:00:00
abstract::Classification into month-specific cutpoints is used to minimize misclassification associated with single measurement of serum 25(OH)D. This study aims to evaluate this strategy, and to compare it with the widely used classification into overall cutpoints. For this purpose, we studied 69,553 subjects in whom serum 25(...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.69
更新日期:2012-09-01 00:00:00
abstract::We conducted a mini-review of the literature, focusing on aging-related systemic inflammation and its association with vitamin D (VitD). As main findings, data indicate that inflammation in aging seems to have multiple origins, including immunosenescence, and from intestinal and adipose tissue, where VitD may modulate...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2016.177
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Mild cognitive impairment (MCI), often considered as an early stage of dementia, is heterogeneous, and not all subjects with MCI progress into clinically diagnosed dementia. Low body weight (and body mass index, BMI) as well as losing weight while in MCI stadium have been proposed as possible risk...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2014.167
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The growing interest of medical community about sarcopenia resulted in the production of several clinical practice guidelines (CPGs), with an unavoidable variability in terms of the overall quality of those publications. Our aim is to evaluate the quality of CPGs on sarcopenia using the AGREE II i...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0638-z
更新日期:2020-08-01 00:00:00
abstract::We have used B-mode (brightness-mode) ultrasound to investigate the fascial planes within subcutaneous fat at the triceps and abdominal sites in a group of 17 women attending a weight control group over a 12 month period. In most subjects there was a single intralipid fascial plane at each site. As the thickness of ad...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:This study investigates the predictors of serum cobalamin concentrations in community-dwelling older adults and the relationship between serum cobalamin and plasma homocysteine. SUBJECTS/METHODS:Serum cobalamin and plasma homocysteine were measured by SimulTRAC-SNB radio assay and HPLC, respectiv...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0367-8
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Protocols for enhanced recovery after surgery (ERAS) provide comprehensive and evidence-based guidelines to improve perioperative care. It remains elusive whether early enteral nutrition (EEN) will play an active role in the ERAS protocols. Laparoscopic common bile duct exploration (LCBDE) is a sa...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-019-0425-x
更新日期:2019-09-01 00:00:00