Abstract:
:We conducted a mini-review of the literature, focusing on aging-related systemic inflammation and its association with vitamin D (VitD). As main findings, data indicate that inflammation in aging seems to have multiple origins, including immunosenescence, and from intestinal and adipose tissue, where VitD may modulate these three factors, through mechanisms not totally known. From the selected studies, three randomized clinical trials of VitD supplementation showed improvements in inflammatory status, whereas two studies did not. Ten epidemiological studies showed associations between VitD and inflammation, whereas two studies did not. One case study reinforced this association. As such, we can assume a reasonable association between VitD and inflammation in the elderly, and a promising role of supplementation in some situations. However, most studies did not take into account environmental and individual factors such as the season of the year, latitude, skin color or even the use of some medicines; in addition, the doses, time of intervention and the sample sizes differed between the studies. In conclusion, although more controlled VitD studies, both clinical and epidemiological, are necessary, it is important to remember the network of factors involved in systemic inflammation in the elderly; an understanding of the dietetic and non-dietetic factors is needed to offer a realistic approach.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Gonçalves de Carvalho CM,Ribeiro SMdoi
10.1038/ejcn.2016.177subject
Has Abstractpub_date
2017-04-01 00:00:00pages
434-440issue
4eissn
0954-3007issn
1476-5640pii
ejcn2016177journal_volume
71pub_type
杂志文章,评审abstract:BACKGROUND/OBJECTIVES:Exposure to polycyclic aromatic hydrocarbons (PAHs) during pregnancy is known to increase oxidative stress, which may influence pregnancy outcomes and health of the child. SUBJECTS/METHODS:This study investigated whether fruit and vegetable intake modifies the relationship between exposure to PAH...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.77
更新日期:2011-10-01 00:00:00
abstract::Effects of dietary intervention on dietary habits and nutrient levels were studied in 240 women aged 50-65 years who had been operated for a stage I-II breast cancer. Following surgery the women who had participated in a dietary history interview were randomly assigned to one of two groups. The intervention group (n =...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-09-01 00:00:00
abstract::Nutrition education for medical students in the University of Otago, New Zealand, has been adapted to comply with the newly introduced system-based teaching. Clinical cases provide the focus for class demonstrations, tutorials, self-directed learning and a limited number of lectures. In the preclinical curriculum nutr...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600805
更新日期:1999-05-01 00:00:00
abstract::A cross-sectional study of 58 infants (age range 2-53 weeks) was carried out in a rural area of northern Thailand. Total dietary intake (energy and protein from breastmilk and supplementary food) was measured directly during continuous observation over 48 h of randomly selected study subjects in their homes. Associati...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::More than 20 years of serological approach to diagnosis of celiac disease (CD) has deeply changed the classical clinical presentation of the disease, and some reports indicate that CD and obesity can coexist in both childhood and adolescence. We reviewed clinical records of 149 children with CD followed in our institu...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.161
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:It is not known if diets lower in greenhouse gas (GHG) emissions are also healthier. We evaluated the population health implications of changing to more sustainable diets in the UK, France, Finland, Italy and Sweden. SUBJECTS/METHODS:We developed a life table model to simulate mortality and morbi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-019-0401-5
更新日期:2019-04-01 00:00:00
abstract::This paper was based on collaborative research efforts from Wageningen University and the University Medical Centre St Radboud in The Netherlands and describes the rationale for web-based nutrition counselling applications in general practice as well as some of the frequently used models and theories (predominantly th...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602185
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:Recent studies suggest that subtle vitamin K depletion has far-reaching consequences. As this entity is not associated with prothrombin time elevation, it is important to determine whether alternate methods can help identify it. We investigated subtle vitamin K depletion in a hospital setting and determined w...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600670
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVE:To study the variation in selenoprotein P levels in serum among healthy subjects from 17 European regions representing nine countries. SUBJECTS:Survey of 414 37-70-year-old subjects (197/217 males/females) from 17 regions. RESULTS:The level of selenoprotein P varied significantly among regions and countries...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Recently, the role of a low-carbohydrate diet in diabetes management has generated interest with claims being made regarding its superiority over the traditional high-carbohydrate, low-fat dietary approach. This systematic review and meta-analysis evaluated the interpretation and effect of a low-c...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,meta分析
doi:10.1038/s41430-017-0019-4
更新日期:2018-03-01 00:00:00
abstract::The basal metabolic rate (BMR) was determined in 14 pairs of monozygotic (MZ; 11 females, 3 males) and 12 pairs of dizygotic (DZ; 10 females, 2 males) twins, with mean ages of 22.7 and 26 years. Zygosity was confirmed using DNA fingerprinting. When BMR was expressed as kJ/d, kJ/kg/d and kJ/kg FFM/d significant intra-c...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:To assess the phytate intake and molar ratios of phytate to calcium, iron and zinc in the diets of people in China. DESIGN:2002 China Nationwide Nutrition and Health Survey is a cross-sectional nationwide representative survey on nutrition and health. The information on dietary intakes was collected using co...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602513
更新日期:2007-03-01 00:00:00
abstract::The growth literature from developing countries is reviewed to assess the extent to which stunting, a phenomenon of early childhood, can be reversed in later childhood and adolescence. The potential for catch-up growth increases as maturation is delayed and the growth period is prolonged. However, maturational delays ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Previous research has shown, in predominantly European populations, that dietary patterns are evident early in life. However, little is known about early-life dietary patterns in Australian children. We aimed to describe dietary patterns of Australian toddlers and their associations with socio-dem...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/ejcn.2013.23
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:To examine the effects of physical activity (PA) in adults with or without prehypertension at baseline on systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension risk by gender. METHODS:A total of 5986 men and 6525 women (≥18 years old) without hypertension-related disease at baselin...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0653-0
更新日期:2020-05-13 00:00:00
abstract:BACKGROUND/OBJECTIVES:B vitamins and related enzymes involved in one-carbon metabolism are necessary for DNA replication, DNA repair and regulation of gene expression. Disruption of one-carbon mechanism may affect cancer risk. We investigated prospectively the relationship between dietary intakes of methionine, B vitam...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.157
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Investigating the effect on post-prandial glycemic and venous serum insulin response of an apple drink following the conversion of its glucose to gluconate. SUBJECTS/METHODS:In a double-blind randomized placebo-controlled clinical trial with cross-over design, 30 male adults with impaired fasting...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-019-0421-1
更新日期:2019-10-01 00:00:00
abstract::Changes in plasma insulin and glucose concentrations before and after feeding were measured in six female subjects (post-obese) who had regained a normal body mass after a history of severe obesity (mean weight loss, 37.1 +/- 2.6 kg). The responses of the post-obese group were compared with a group of weight- and age-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of cold storage and vinegar addition on glycaemic and insulinaemic responses to a potato meal in healthy subjects. SUBJECTS AND SETTING:A total of 13 healthy subjects volunteered for the study, and the tests were performed at Applied Nutrition and Food Chemistry, Lund University, S...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:10.1038/sj.ejcn.1602238
更新日期:2005-11-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.242
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the Europe...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
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更新日期:2014-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is convincing evidence that a high dietary fiber intake may lower the risk of coronary heart disease. However, the role of fiber in the prevention of stroke is unclear. We examined the associations of dietary fiber and fiber-rich food intake with risk of stroke within the Alpha-tocopherol, B...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.16
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To assess the effect of zinc supplementation on respiratory tract disease, immunity and growth in malnourished children. DESIGN:A randomized double-blind placebo-controlled trial. SETTING:A day-care center in Quito, Ecuador. SUBJECTS:Fifty children (12-59 months old) recruited by height-for-age and weight-...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-01-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
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更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To study the association between dietary and serum antioxidant vitamins and carotenoids and risk for colorectal cancer in male smokers. DESIGN:A prospective cohort study within a randomised, double-blind, placebo-controlled trial testing supplementation with alpha-tocopherol (50 mg/day), beta-carotene (20 mg...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601366
更新日期:2002-07-01 00:00:00
abstract::A World Health Organization (WHO) Expert Consultation on Waist Circumference (WC) and Waist-Hip Ratio (WHR) was convened in Geneva from 8 to 11 December 2008 to consider approaches to developing international guidelines for indices and action levels in order to characterize health risks associated with these measures ...
journal_title:European journal of clinical nutrition
pub_type:
doi:10.1038/ejcn.2009.139
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Gains in fat mass and lean mass during tuberculosis (TB) treatment may determine functional recovery and survival; yet, data are scarce. We aimed to assess predictors of fat and fat-free mass during 2 months of intensive TB treatment in a cohort in Mwanza, Tanzania. SUBJECTS/METHODS:Fat and fat-f...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.37
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Twins in developing countries may be disadvantaged due to their small size at birth, compromised nutrition and high infection risk. Although twinning is common in Africa, there are few longitudinal studies of growth and morbidity in this high-risk group. The aim of the present paper was to describe growth and...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602356
更新日期:2006-05-01 00:00:00
abstract::The present study tested the hypotheses that: (a) individual body composition estimates obtained with the Durnin-Womersley (D-W) equations have low validity in certain populations in developing countries; (b) there exists a poor relationship between the body mass index (BMI) and body composition estimates (fat mass (B...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Although the impact of passive video games (PVGs) on energy intake has been previously explored in lean adolescents, data are missing on the nutritional adaptations to passive and active video games (AVGs) in obese adolescents. It is also unknown whether isoenergetic AVGs and exercise (EX) differe...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.31
更新日期:2015-11-01 00:00:00