Abstract:
OBJECTIVE:To investigate the impact of intensive lifestyle education on dietary practices, exercise and metabolic measurements in people with insulin-dependent diabetes mellitus (IDDM). DESIGN:Sixty-one volunteer subjects with IDDM were randomised to intensive (Group 1) or standard (Group 2) education programmes for six months. During a second six month period of observation Group 1 subjects received routine surveillance for their condition and those in Group 2 were given intensive advice (phase 2). Current insulin regimens were modified to optimise glycaemic control before the start of the intervention phase. Nutrient intakes, weight, blood pressure, glycated haemoglobin (HbA1), plasma lipids, lipoproteins and maximal oxygen consumption (VO2 max) were measured at the time of recruitment and at three monthly intervals during the trial and phase 2. SETTING:Department of Human Nutrition at the University of Otago. RESULTS:Glycated haemoglobin decreased significantly in both groups between recruitment and randomisation, the improvement being sustained during the six months of the randomised trial and for group 1 during the six months of post trial observation. A further decrease was seen in Group 2 during the second six month period when they were given intensive advice. Comparable changes were seen with total and low density lipoprotein (LDL) cholesterol in Group 1 during the trial, but significant decreases were only seen in Group 2 in association with intensive intervention (phase 2). These changes occurred in parallel with increases in intakes of carbohydrate and monounsaturated fatty acids, a reduction in intakes of total and saturated fat, and an improvement in maximum oxygen consumption. CONCLUSIONS:A lifestyle programme for people with IDDM results in modest changes in diet and exercise habits sufficient to improve measures of glycaemic control and lipoprotein mediated risk of coronary heart disease independent of changes in insulin regime. More innovative approaches to achieve lifestyle changes are required to meet current recommendations which in turn are likely to produce even greater beneficial changes than those observed here.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Perry TL,Mann JI,Lewis-Barned NJ,Duncan AW,Waldron MA,Thompson Cdoi
10.1038/sj.ejcn.1600478subject
Has Abstractpub_date
1997-11-01 00:00:00pages
757-63issue
11eissn
0954-3007issn
1476-5640journal_volume
51pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVES:The effect of consumption of a wheat-flour bread-based low-fibre diet (7.8 g/day fibre; 1.0 portion) or the same diet in which the wheat bread was exchange for a bread based on oat bran with a high fibre content (31.9 g/day fibre; 1.0 portion) on the ileal excretion of amino acid residues and crude protein w...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1995-08-01 00:00:00
abstract::Postprandial thermogenesis was assessed by indirect calorimetry in 32 Gambian women classified into three groups as follows: 12 non-pregnant non-lactating and 10 lactating women studied during the dry season and 10 lactating women studied during the rainy season. The test meal consisted of a typical Gambian breakfast ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The purpose of this work was to investigate the association between coffee drinking and diabetes development and potential mediation by oxidative stress and inflammatory biomarkers. SUBJECTS/METHODS:In 2001-2002, a random sample of 1514 men (18-87 years old) and 1528 women (18-89 years old) were ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.98
更新日期:2015-11-01 00:00:00
abstract::This review outlines a hypothesis that A1 one of the common variants of beta-casein, a major protein in cows milk could facilitate the immunological processes that lead to type I diabetes (DM-I). It was subsequently suggested that A1 beta-casein may also be a risk factor for coronary heart disease (CHD), based on betw...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1602104
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVE:Total body water can be calculated using stable isotopes by two alternative approaches known as the plateau method and the back extrapolation method. These methods treat the isotopic data in different ways and consequently do not necessarily produce identical values for total body water. Total body water was ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Neuropeptide Y (NpY) is an important factor in neuropeptide signalling, and significantly change in the blood and cerebrospinal fluid (CSF) during chronic kidney disease (CKD) progression. However, the role of NpY remains unclear. We aimed to investigate the associations between NpY levels, nutrit...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.67
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:Nutritional deficiency is an independent risk factor for mortality. Despite its clinical relevance, the prevalence in a primary care setting is poorly documented. We performed a systematic review of reported prevalence and clinical assessment of nutritional deficiency in general practice. METHODS:From MEDLIN...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1602178
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the in vivo effects of moderate consumption of red wine, beer and spirits on antioxidants, antioxidant enzymes and antioxidant capacity. DESIGN:Randomized, diet-controlled, cross-over study. SUBJECTS:Twelve apparently healthy, non-smoking middle-aged men were included; 11 of them completed the s...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601061
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:Pregnant women in developing countries might be at risk of trace element deficiencies. These deficiencies could have deleterious effects on fetus. Therefore, serum trace elements were determined at delivery in Zairian mothers and their newborns. DESIGN:Prospective study. SETTING:Maternity ward of Kinshasa ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::The present study was conducted to test the efficacy of fibre supplementation for hypercholesterolaemia in subjects from the desert Nomads. Ten males (53 +/- 8 years of age) participated in this study which consisted of three phases: baseline-1 period (2 weeks) in which subjects were on their normal, habitual dietary ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Longitudinal studies investigating dietary patterns (DPs) and their association with childhood overweight/obesity are lacking in Europe. We identified DPs and investigated their association with overweight/obesity and changes in body mass index (BMI) in a cohort of European children. SUBJECTS/MET...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2013.145
更新日期:2013-10-01 00:00:00
abstract::Glycaemic variability challenges the accuracy and use of the glycaemic index (GI). The purpose of the current study was to determine the role of mastication on GI. Using a randomized, controlled, crossover, non-blind design, 15 healthy young subjects returned on 5 separate days for three glucose and two rice test sess...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2013.231
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To explore the different characteristics of high and low fat consumers, in particular their macronutrient intake and body mass index. DESIGN:Reanalysis of data from the Dietary and Nutritional Survey of British Adults. Comparisons were made between groups defined as high and low fat consumers on the basis o...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of fatty liver and alanine aminotransferase (ALT) elevation in obese Japanese women and to clarify the factors contributing to fatty change and ALT elevation in the cohort. DESIGN:Cross-sectional and population-based study. SUBJECTS:From 4366 women who received their annual healt...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601956
更新日期:2004-09-01 00:00:00
abstract::As part of the Euronut SENECA study, food consumption has been assessed in 1217 men and 1241 women, born between 1913 and 1918 and living in 18 towns in 12 European countries. The method used was a standardized modified dietary history, including a 3-day estimated record and a food frequency list based on local food p...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVE:To determine folates, vitamin B12 and total homocysteine levels among neonates from mothers of low or high socioeconomic status. DESIGN:We carried out a cross-sectional transversal study comprising 143 neonates from two maternity hospitals in the city of Salvador, Northeast of Brazil. Cord blood samples were...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602528
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To determine whether dual-energy X-ray absorptiometry (DXA) is a valid method for body composition assessment of obese and non-obese subjects. DESIGN:Cross-sectional study. SUBJECTS:Chinese women living in Hong Kong; 66 of 91 subjects had body mass index (BMI) of >25 kg/m2. MEASUREMENTS:Anthropometrics, in...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600875
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To compile curves for Body Mass Index (BMI) for Italian children and adolescents. DESIGN:Cross sectional study. SETTING:All primary and secondary schools of Verona, Italy between October 1986 and January 1987. SUBJECTS:20,796 males and 21,073 females children, aged 3-19 y. METHODS:Weight and height were m...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600326
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To assess dietary patterns (DPs) in European adolescents and to examine their relationship with several indicators of sedentary behaviour. SUBJECTS/METHODS:A multinational cross-sectional study was carried out in 2202 adolescents (45.4% boys) aged 12.5-17.5 years. A self-reported questionnaire wi...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.170
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the Europe...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2013.235
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The cardiovascular benefit of increasing fruit and vegetable (F&V) intake following diagnosis of diabetes remains unknown. We aimed to describe how quantity and variety of F&V intake, and plasma vitamin C, change after diagnosis of type 2 diabetes and examine whether these changes are associated w...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.180
更新日期:2017-01-01 00:00:00
abstract::We investigated the inhibitory effect of calcium on iron absorption in 57 human subjects. Three studies suggested that the effect is not located in the gastrointestinal tract. The presence of phytate in a meal and formation of calcium-iron-phytate complexes is not a prerequisite for the inhibition. The relative increa...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract:OBJECTIVE:To assess the bioavailability of vitamins A and E administered parenterally with either water-soluble or lipid-soluble preparations. STUDY DESIGN:A water soluble preparation (MVI Pediatric) administered with a glucose-amino acid solution and a lipid soluble preparation (Vitalipid N Infant) infused with a lip...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601417
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:To determine the nature of the relationship between mid-upper arm circumference (MUAC) and maximum voluntary contraction (MVC) in pre- and post-harvest seasons among adult Ethiopian farmers. SUBJECTS/METHODS:A total of 491 healthy adult men aged 18-60 years were recruited at pre-harvest season and followed ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602966
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:No prospective study on the long-term effects of gastric resection on gastrointestinal hormonal changes in patients with normal body weight has been reported. The aim of this study was to evaluate the 1-year effect of subtotal gastrectomy on ghrelin and peptide YY (PYY)(3-36) levels. SUBJECTS/MET...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.83
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To describe the secular trends in the prevalence rates of iron-deficiency anemia (IDA) in infants in Israel, identify population group differences and assess the effectiveness of the 1985 Public Health directives on iron supplementation and avoidance of cow's milk in the first year of life. DESIGN:A systemat...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601119
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To investigate the association between dietary patterns and risk of a first nonfatal acute myocardial infarction (MI) in Costa Rican adults. DESIGN:Population-based case-control study. SUBJECTS:A total of 496 incident MI cases and 518 population-based randomly selected controls matched to the cases by age (...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602381
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To determine the origin of the poor digestibility of banana starch granules in the human small intestine. DESIGN:The subjects received the same experimental meal. SETTING:Nutrition Research Unit, Laënnec Hospital, CHU, Nantes. SUBJECTS:Six healthy young subjects. INTERVENTIONS:The digestion of raw green b...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:This study investigated whether postprandial metabolic responses to bread could be lowered by substituting high amylose maize starch for a part of the flour. DESIGN AND SUBJECTS:Eight healthy subjects consumed test meals of equivalent nutritional composition based on white wheat bread, bread rich in amylose ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600718
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To determine whether the age-related decrease in resting energy expenditure (REE) is explained by variations in body composition. DESIGN:In Study 1, adult subjects (20-70 years) from the Quebec Family Study were classified into five different age groups. Body composition was measured by hydrodensitometry to ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602262
更新日期:2006-01-01 00:00:00