Abstract:
OBJECTIVE:To determine folates, vitamin B12 and total homocysteine levels among neonates from mothers of low or high socioeconomic status. DESIGN:We carried out a cross-sectional transversal study comprising 143 neonates from two maternity hospitals in the city of Salvador, Northeast of Brazil. Cord blood samples were obtained at the time of delivery from newborns from low (group 1, n=77) or high (group 2, n=66) socioeconomic status. The vitamin B12 and folates were analyzed by electrochemiluminescence immunoassay and by a competitive test using a natural folate-binding protein (FBP), respectively. Total homocyteine levels were measured by fluorescence polarization immunoassay. Maternal environmental risk factors for pregnancy complications were obtained from all mothers. RESULTS:Only 2% of women from group 1 received prenatal care/vitamin supplementation, whereas almost all mothers from group 2 (96%) were properly followed. Anemia and/or infections pre- or during pregnancy was more prevalent among mothers of babies from group 1. Folate levels among newborns from group 1 and 2 were 7.38+/-2.71 and 8.83+/-4.06 ng/ml, respectively. No difference in the vitamin B12 levels was determined between groups. In addition, tHcy serum levels were higher among newborns from group 1 compared to those from group 2 (8.54+/-4.06 vs 6.35+/-1.33 micromol/l, respectively; P=0.005). CONCLUSION:These results demonstrate that unprivileged young woman has limited accesses to prenatal care, present high-risk factors that hamper both maternal and newborn health. Maternal and newborn health status could be improved by simply reinforcing the use of folate-enriched diet. The work presented illustrates the challenges that developing countries have to face in order to provide preventive adequate health care to the population at large.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Couto FD,Moreira LM,Dos Santos DB,Reis MG,Gonçalves MSdoi
10.1038/sj.ejcn.1602528subject
Has Abstractpub_date
2007-03-01 00:00:00pages
382-6issue
3eissn
0954-3007issn
1476-5640pii
1602528journal_volume
61pub_type
杂志文章abstract::Hydrolysed yeast protein labelled with 15N was used to measure protein turnover, protein synthesis and protein breakdown in preterm infants. The yeast tracer was given as a bolus intragastric dose and protein turnover was determined from the 15N enrichment of urinary ammonia over known periods of about 12 h. Six boys ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::The nutritional impact of a water and sanitation intervention in a rural community of Bangladesh, comprising the provision of handpumps, construction of latrines and hygiene education was assessed. During 3 years, the quarterly anthropometric measures of about 200 children aged 12-35 months from the intervention commu...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVE:We investigated the effects of mineral water fortified with folic acid, vitamins B(6), B(12), D and calcium on folate concentrations in serum and erythrocytes, serum vitamin B(12) and plasma homocysteine concentrations in free-living subjects. In addition, we investigated the bioavailability of calcium added ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601795
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The use of simple screening tools to measure nutritional adequacy in a public health context in developed countries are currently lacking. We explore the relationship between food variety and nutrient intake of London school children using a simple tool with potential use for screening for inadequ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-017-0070-1
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abstract::The success of the Human Genome Project and the spectacular development of broad genomics tools have catalyzed a new era in both medicine and nutrition. The terms pharmacogenomics and nutrigenomics are relatively new. Both have grown out of their genetic forbears as large-scale genomics technologies have been develope...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1602590
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abstract:BACKGROUND/OBJECTIVES:Youth with type 1 diabetes (T1DM) are at substantially increased risk for adverse vascular outcomes, but little is known about the influence of dietary behavior on cardiovascular disease (CVD) risk profile. We aimed to identify dietary intake patterns associated with CVD risk factors and evaluate ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/ejcn.2014.96
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To examine the effect of acute fluid consumption on measures of impedance and percent body fat (%BF) using a common leg-to-leg bioelectrical impedance analyzer system. DESIGN:Cross-sectional design with treatment order determined using a counterbalanced assignment. SETTING:University laboratory. SUBJECTS:I...
journal_title:European journal of clinical nutrition
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abstract::The effect of adjusting height-weight indices for frame size on the prediction of body fatness was investigated in a community sample of 2512 men aged 45-59 years. Body fatness was assessed from skinfold thickness measurements at four sites: triceps, biceps, subscapular and supra-iliac. Body diameters (biacromial, bi-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:There is a continuing need to examine the relationship between diet quality and health in the population. The Healthy Eating Index (HEI) has been developed as a composite measure of diet quality by the US Department of Agriculture. OBJECTIVES:The first objective was to use the HEI to assess the diet quality...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601989
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To compare the relations of adiposity and body fat distribution to body mass index (BMI) in Australians of Aboriginal and European ancestry. DESIGN:Cross-sectional volunteer samples. SETTING:Australian Aboriginal communities in remote central and northern Australia, urban European Australians resident in Me...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601630
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To elucidate gender differences in dietary intake among adults in lowland Nepalese communities. SUBJECTS AND METHODS:For 122 male and 195 female subjects aged 20 years and over from 94 randomly selected households, interviews using a 19-item food frequency questionnaire were conducted. To determine the porti...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602339
更新日期:2006-04-01 00:00:00
abstract::The aim of this survey was to examine differences in personality profiles among 198 vegan (n = 64; 32.3%), vegetarian (n = 78; 39.4%) and omnivore (n = 55; 27.8%) medical professionals. Outcomes were motives for the nutritional approaches, WHO QoL-BREF, Big Five SOEP Inventory, Portraits Value Questionnaire, and Empat...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-017-0007-8
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Patients with a short bowel and receiving parenteral nutrition (PN) have an increased risk of chronic cholestasis (CC). Restoration of bowel continuity after a mesenteric infarction results in PN requirements being reduced or stopped. This study aimed to determine the prevalence of CC and whether ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.147
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:We set up a baseline data on urinary iodine excretion from a nationwide representative sample of rural schoolchildren before instituting iodine supplementation. DESIGN:Stratified multistage cluster sampling in three different strata: lowlands, foothills and mountainous areas. Early morning urine samples were...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600562
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To assess the carotenoid status in young type I diabetic patients and its relationship to the glycaemic control of the disease. DESIGN:A follow-up study. SETTING:Hospital Universitario Puerta de Hierro, Health Area VI of Madrid (Spain). SUBJECTS:Forty-seven type I diabetic patients, followed for 2.5 years....
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602411
更新日期:2006-08-01 00:00:00
abstract::Chronic diseases and disabilities increase with age, affecting more than 60% of those over 75 y, and limiting activities in about half of them. Therefore, total energy expenditure (TEE) and its components are assessed separately in health and disease. An analysis of 568 doubly labelled water measurements in 'healthy' ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601030
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Adult skeletal muscle mass (SMM) protects against type 2 diabetes, but little is known about its developmental antecedents. We examined whether pace of early weight gain predicted adult SMM in a birth cohort from Cebu City, Philippines. In addition, we examined whether increases in SMM associated ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.18
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Hypoglycemic effect of camel milk supplementation in experimental rat model and significant reduction in doses of insulin in type 1 diabetic patients have been observed in our previous studies. This long-term study was undertaken to assess the efficacy, safety and acceptability of camel milk as an...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2011.98
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:To study the relationship between lipid, fatty acid and lipid-rich food intake and current asthma in a group of Spanish schoolchildren. SUBJECTS/METHODS:The subjects of this cross-sectional study were 638 Spanish schoolchildren (8-13 years of age). The weight and height of all the subjects were recorded. A ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.127
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings. SUBJECTS/METHODS:This is an observational analysis of 1078 HIV-infected pregnant women enrolled in a trial of vitamin supp...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2010.76
更新日期:2010-08-01 00:00:00
abstract::The refeeding syndrome is a potentially fatal condition that affects multiple organ systems. It is the consequence of fluid and electrolyte shifts that may occur in a malnourished patient following the introduction of nutrition therapy. The most prominent characteristic is hypophosphataemia. Although hyperammonaemia i...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.244
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:To study the association between content in adipose tissue of very long-chain n-3 fatty acids, trans fatty acids, linoleic acid and alpha-linolenic acid and risk of a first myocardial infarction. DESIGN AND SUBJECTS:A case-control design among 100 patients and 98 population controls both men and postmenopau...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601064
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of irregular meal frequency on circulating lipids, insulin, glucose and uric acid concentrations which are known cardiovascular risk factors. DESIGN:A randomised crossover dietary intervention study. SETTING:Nottingham, UK--Healthy free-living women. SUBJECTS:A total of nine lean ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601935
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the major dietary patterns of two age cohorts of women, to determine to the extent to which the dietary patterns differ between the cohorts and to assess whether they vary according to sociodemographic and behavioural characteristics and patterns of nutrient intake. METHOD...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.121
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To assess the validity of two diet quality indexes-food variety score (FVS) and diet diversity score (DDS) in Western Mali. DESIGN:In two separate studies (A and B), FVS and DDS were derived from a food frequency questionnaire (FFQ) and were compared with the same scores and with measures of nutrient adequac...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601686
更新日期:2003-10-01 00:00:00
abstract::Glycaemic variability challenges the accuracy and use of the glycaemic index (GI). The purpose of the current study was to determine the role of mastication on GI. Using a randomized, controlled, crossover, non-blind design, 15 healthy young subjects returned on 5 separate days for three glucose and two rice test sess...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2013.231
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies. SUBJECTS AND METHODS:Twenty-six women born between 1940 and 1950 were recruited ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602811
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To assess the differential response of plasma, lymphocyte and neutrophil vitamin E levels to high-intensity physical activity and to vitamin C and E supplementation. SUBJECTS:In all, 14 male trained amateur runners (32-36 y old) were randomly divided in two groups (supplemented and placebo), and participated...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602143
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Previous small studies have shown either no difference or a lower risk of symptomatic gallstone disease in vegetarians than in non-vegetarians. This study examined the incidence of symptomatic gallstone disease in a cohort of British vegetarians and non-vegetarians, and investigated the associatio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.252
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:It was determined whether a combination of Lactobacillus acidophilus (L. acidophilus) 74-2 and Bifidobacterium animalis subsp lactis DGCC 420 (B. lactis 420) affect the faecal microbiota as well as immunological parameters and blood lipids in healthy adults. DESIGN:A placebo-controlled, double-blinded, rando...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602761
更新日期:2008-05-01 00:00:00