Abstract：
OBJECTIVE:To assess the carotenoid status in young type I diabetic patients and its relationship to the glycaemic control of the disease. DESIGN:A follow-up study. SETTING:Hospital Universitario Puerta de Hierro, Health Area VI of Madrid (Spain). SUBJECTS:Forty-seven type I diabetic patients, followed for 2.5 years. INTERVENTIONS:Coinciding with physical examination and laboratory tests, serum levels of carotenoids were analysed by HPLC, and dietary intake of carotenoids was evaluated by a semiquantitative food frequency questionnaire and 3-day prospective dietary records. RESULTS:In type I diabetic patients, average intake, serum levels and correlations between diet and serum levels of carotenoids were comparable to those in reference non-diabetic groups. Between-subjects seasonal variations were observed for beta-cryptoxanthin intake and serum levels (higher in winter) and serum lycopene (higher in summer). Significant within-subjects seasonal changes were shown for dietary and serum beta-cryptoxanthin and serum beta-carotene. Serum carotenoids were unrelated to glycaemic control markers. Subjects with clinically acceptable glycaemic control showed lower lycopene intake than those with unacceptable control. Intake of carotenoids did not explain variance in insulin dose, fasting glycaemia, fructosamine or HbA1c. With the exception of lycopene, serum carotenoids were predicted by dietary intake, but in no case by fasting glycaemia, HbA1c or fructosamine. CONCLUSION:In type I diabetic patients, serum carotenoid concentrations and their variance are determined by dietary intake patterns, and are unrelated to the glycaemic control of the disease, as assessed by biochemical markers.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Granado-Lorencio F,Olmedilla-Alonso B,Blanco-Navarro I,Botella-Romero F,Simal-Antón Adoi
10.1038/sj.ejcn.1602411subject
Has Abstractpub_date
2006-08-01 00:00:00pages
1000-8issue
8eissn
0954-3007issn
1476-5640pii
1602411journal_volume
60pub_type
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abstract：:Infant feeding pattern was studied longitudinally from birth to 52 weeks among all infants born in the period September 1982-December 1984 in three villages in Madura, East Java (n = 687). Genuine demand breast-feeding was practised but it is the custom to force-feed infants from as early as the third day after birth ...
journal_title：European journal of clinical nutrition
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abstract：OBJECTIVES:We examined the effects of a high fat diet rich in monounsaturated fat (MUFA-diet) and a moderate fat diet rich in polyunsaturated fat (PUFA-diet) on the susceptibility of LDL to oxidation. SUBJECTS:29 subjects with impaired glucose tolerance. METHODS:After consuming a run-in diet [37% of energy (E%) fat, ...
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pub_type： 临床试验,杂志文章,随机对照试验
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pub_type： 杂志文章,评审
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
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journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
