Abstract：
:Chronic diseases and disabilities increase with age, affecting more than 60% of those over 75 y, and limiting activities in about half of them. Therefore, total energy expenditure (TEE) and its components are assessed separately in health and disease. An analysis of 568 doubly labelled water measurements in 'healthy' subjects (184 measurements in subjects over 65 years) suggests that there is a decrease of 0.69 and 0.43 MJ/day/decade respectively in men (standard weight 75 kg) and women (standard weight 67 kg). Physical activity (PA) accounted for 46% of the decrease in TEE, basal metabolic rate (BMR) for 44% of the decrease and thermogenesis (T) for the remaining 10%. TEE was found to be 10.79+/-2.09 and 8.62+/-1.49 MJ/day in 150 men and 100 women aged over 60 y, respectively. Of the total variance in TEE, measured with doubly labelled water over a 2 week period, 69% was considered to be due to differences between individuals, and 31% to differences within individuals. The variance due to PA plus T was threefold greater than that due to BMR. Physiological factors were far more important than methodological factors in influencing measurements of TEE, BMR and PA+T. An analysis of 136 measurements of TEE (doubly labelled water and bicarbonate-urea methods) in free-living elderly patients suffering from a variety of diseases suggests a frequent decrease in TEE, which may occur despite an increase in BMR. This is largely due to a reduction is PA (eg up to approximately 50% reduction), but in some cases it is also due to a reduction in BMR (loss of body weight). More comprehensive information is required about TEE and its components, partly because of a probable selection bias in recruitment of subjects participating in specific tracer studies, and partly because of the variable effects of different diseases and factors that operate at different times in the course of the same disease.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Elia M,Ritz P,Stubbs RJdoi
10.1038/sj.ejcn.1601030subject
Has Abstractpub_date
2000-06-01 00:00:00pages
S92-103eissn
0954-3007issn
1476-5640journal_volume
54 Suppl 3pub_type
杂志文章,评审abstract：BACKGROUND/OBJECTIVES:The aim was to investigate the effects of a conventional and an unconventional fast-food meal on postprandial metabolism in normal and in overweight subjects. SUBJECTS/METHODS:Twenty-five healthy normal (n = 12) and overweight (n = 13) volunteers (21-39 years) participated in this randomized, die...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2012.125
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Both self-reported dietary information and urinary excretion have limitations in the assessment of phosphorus intake. We conducted a cross-sectional study to estimate dietary phosphorus intake by dietary records (DR) and 24-h urine collections (UC) and examined associated factors. SUBJECTS/METHOD...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0114-1
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Mild cognitive impairment (MCI), often considered as an early stage of dementia, is heterogeneous, and not all subjects with MCI progress into clinically diagnosed dementia. Low body weight (and body mass index, BMI) as well as losing weight while in MCI stadium have been proposed as possible risk...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2014.167
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk retinol concentration. METHODS:Fifty low income women were randomly assigned to a single oral dose of 209 micromol of Vitamin A or none at delivery. Maternal serum and breastmilk retinol levels and infant morbidity and ant...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1600398
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To assess the effects in humans of regular ingestion of black tea on haemostasis-related variables and cell adhesion molecules. DESIGN:Twenty-two subjects were recruited from the general population to a randomised-controlled crossover study. Subjects stopped drinking tea, apart from that provided, for the du...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601231
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Sarcopenia and sarcopenic obesity (SO) are geriatric syndromes leading to physical disability, poor quality of life and death. The aim of this study was to investigate the prevalence of sarcopenia and SO in nursing homes in Turkey and to define local disparities for diagnosing sarcopenia and SO. ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究
doi：10.1038/ejcn.2014.15
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:These two studies compared the subjective assessment of how filling a snack type would be, with actual consumption of that type of snack at a snack meal. DESIGN:Four snack types: savory high-fat, savory high-carbohydrate, sweet high-carbohydrate, each comprising of five food items, were used. Study 1 consist...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:While putative feedback signals arising from adipose tissue are commonly assumed to provide the molecular links between the body's long-term energy requirements and energy intake, the available evidence suggests that the lean body or fat-free mass (FFM) also plays a role in the drive to eat. A distinction must, howeve...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2016.256
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Maternal dietary patterns were associated with embryonic growth and congenital anomalies. We aim to evaluate associations between early first trimester maternal dietary patterns and embryonic morphological development among pregnancies with non-malformed outcome. SUBJECTS/METHODS:A total of 228 s...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0161-7
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Consumption of fruit and vegetables (F&V) is associated with a lower cardiovascular disease (CVD) risk. Smoking may affect the strength of this association. The objective of this study was to compare the relationship between the frequency of F&V intake and CVD risk in male current, former and neve...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.46
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To objectively measure rates of breast-feeding to infants born in a baby-friendly hospital in Bangalore, India, and to capture home-based compliance to exclusive breastfeeding (EBF). SUBJECTS/METHODS:Breast-milk (BM) and non-breast-milk (NBM) water intake were assessed in 50 mother-infant pairs u...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2011.179
更新日期：2012-04-01 00:00:00
abstract：:This article was originally published under Nature Research's License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the article have been modified accordingly. ...
journal_title：European journal of clinical nutrition
pub_type： 已发布勘误
doi：10.1038/s41430-020-00776-3
更新日期：2020-10-15 00:00:00
abstract：BACKGROUND/OBJECTIVES:While beverages are an important dietary source of water and some essential nutrients, consumption of sweet beverages has increasingly been linked to adverse health outcomes. Currently there is a paucity of longitudinal consumption data on beverage consumption in Australian children. SUBJECTS/MET...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-017-0021-x
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To assess the effects of supplementation with the carotenoids, beta-carotene or lycopene, at levels achievable within a diet rich in fruit and vegetables, on immune function in a group of free-living healthy elderly. DESIGN:A double-blind randomized placebo-controlled trial. T cell subsets and the expression...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601187
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To compare body fat mass at the same stage of pubertal maturation, genital stage 2 (G2), in a Spanish and in a Mexican sample of boys. SUBJECTS/METHODS:Data from Spain (n=177) were from a previous longitudinal clinical follow-up and data from Mexico (n=91) from a cross-sectional study. Subjects w...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2008.37
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:The EURRECA (EURopean micronutrient RECommendations Aligned) Network of Excellence collated current micronutrient recommendations. A user-friendly tool, Nutri-RecQuest, was developed to allow access to the collated data and to create a database source for use in other nutritional software tools. METHODS:Rec...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.60
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVES:The effect of consumption of a wheat-flour bread-based low-fibre diet (7.8 g/day fibre; 1.0 portion) or the same diet in which the wheat bread was exchange for a bread based on oat bran with a high fibre content (31.9 g/day fibre; 1.0 portion) on the ileal excretion of amino acid residues and crude protein w...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-08-01 00:00:00
abstract：:The present study was conducted to test the efficacy of fibre supplementation for hypercholesterolaemia in subjects from the desert Nomads. Ten males (53 +/- 8 years of age) participated in this study which consisted of three phases: baseline-1 period (2 weeks) in which subjects were on their normal, habitual dietary ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:In spite of several studies relating dietary patterns to breast cancer risk, evidence so far remains inconsistent. This study aimed to investigate associations of dietary patterns derived with three different methods with breast cancer risk. SUBJECTS/METHODS:The Mediterranean Diet Score (MDS), pr...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究
doi：10.1038/ejcn.2014.135
更新日期：2014-12-01 00:00:00
abstract：:The aim of this survey was to examine differences in personality profiles among 198 vegan (n = 64; 32.3%), vegetarian (n = 78; 39.4%) and omnivore (n = 55; 27.8%) medical professionals. Outcomes were motives for the nutritional approaches, WHO QoL-BREF, Big Five SOEP Inventory, Portraits Value Questionnaire, and Empat...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-017-0007-8
更新日期：2018-05-01 00:00:00
abstract：OBJECTIVE:To investigate the separate and combined effect of wine-drinking and other alcoholic beverages on esophageal cancer, in a high wine-consuming population. DESIGN:Combined analysis of two hospital-based case-control studies. SETTING:Major teaching and general hospitals in the greater Milan area and in the pro...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601113
更新日期：2000-12-01 00:00:00
abstract：:Bone marrow transplantation is often associated with multiple organ failure which is usually reversible. Oral mucositis and dysphagia, vomiting, diarrhoea, protein losing enteropathy, transient exocrine pancreatic impairment, hypoalbuminaemia, biochemical trace element and mineral deficiencies are all common following...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1600669
更新日期：1998-12-01 00:00:00
abstract：:Data from four central European dietary investigations carried out between 1982 and 1984 in the German Democratic Republic, Poland and the Federal Republic of Germany applying both a food frequency questionnaire (FFQ) and a quantitative recording instrument (24-h recall, 3-d record or 10- to 14-d record) were analysed...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：:Aging is the major risk factor for the development of human neurodegenerative maladies such as Alzheimer's, Huntington's and Parkinson's diseases (PDs) and prion disorders, all of which stem from toxic protein aggregation. All of these diseases are correlated with cognitive decline. Cognitive Decline is a dynamic stat...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/ejcn.2014.189
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To assess the genetic and nongenetic correlates of circulating measures of vitamins K and D status in a community-based sample of men and women. SUBJECTS/METHODS:A cross-sectional study of 1762 participants of the Framingham Offspring Study (919 women; mean age 59 years). Vitamin K status was measured as pla...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602959
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To assess how food shortage has been reflected in changes in nutritional status and dietary intake of resident and refugee populations in wartime Sarajevo. DESIGN:Longitudinal observations were carried out on residents (who stayed in their homes) and refugees (living in collective centres). Three out of four...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:The objective of this study is to determine the relative validity of reported energy intake (EI) derived from multiple 24-h recalls against estimated energy expenditure (EE(est)). Basal metabolic rate (BMR) equations and physical activity factors were incorporated to calculate EE(est). SUBJECTS/ME...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2011.60
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients. SUBJECTS/METHODS:Handgrip strength was measured with Jamar dynamometer in 620 hospitalized patients (56.4±15.9 years old, 52.3...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2013.261
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To study the relation between indicators of infection and Schistosoma mansoni and S. haematobium infection, and serum concentrations of zinc, ferritin and retinol. DESIGN:Cross-sectional. SETTING AND SUBJECTS:313 rural Zimbabwean schoolchildren (144 boys and 169 girls, 11-17 years). VARIABLES:S. mansoni an...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:Nutritional deficiency is an independent risk factor for mortality. Despite its clinical relevance, the prevalence in a primary care setting is poorly documented. We performed a systematic review of reported prevalence and clinical assessment of nutritional deficiency in general practice. METHODS:From MEDLIN...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1038/sj.ejcn.1602178
更新日期：2005-08-01 00:00:00
