Abstract:
BACKGROUND/OBJECTIVES:No prospective study on the long-term effects of gastric resection on gastrointestinal hormonal changes in patients with normal body weight has been reported. The aim of this study was to evaluate the 1-year effect of subtotal gastrectomy on ghrelin and peptide YY (PYY)(3-36) levels. SUBJECTS/METHODS:Eighteen patients with early gastric cancer underwent subtotal gastrectomy with Billroth I reconstruction. We assessed appetite, food intake, body composition, and ghrelin and PYY(3-36) levels preoperatively and 1 year after surgery. RESULTS:There were no significant difference in the preoperative daily food intake and 1 year after subtotal gastrectomy. Weight loss occurred in all study subjects; 11.7% (n=2), 55.5% (n=10) and 33.3% (n=6) of the patients lost <5%, 5-10% and >10% of their preoperative body weight, respectively. Body mass index, waist circumference and body fat significantly decreased 1 year after subtotal gastrectomy. There were no significant differences in the appetite visual analogue scale preoperatively and 1 year after subtotal gastrectomy. The plasma ghrelin concentration decreased significantly (P=0.006), whereas PYY(3-36) did not show a significant change 1 year after subtotal gastrectomy. CONCLUSIONS:Ghrelin levels and body fat decreased significantly, whereas PYY(3-36) levels as well as appetite and food intake did not change significantly 1 year after subtotal gastrectomy with normal body weight. These findings suggest that decreased ghrelin might contribute directly to reduced body fat.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Jeon TY,Lee S,Kim HH,Kim YJ,Lee JG,Jeong DW,Kim YJdoi
10.1038/ejcn.2010.83subject
Has Abstractpub_date
2010-08-01 00:00:00pages
826-31issue
8eissn
0954-3007issn
1476-5640pii
ejcn201083journal_volume
64pub_type
杂志文章abstract:OBJECTIVE:We investigated whether there was a growth or morbidity response to zinc supplementation. DESIGN:The study was randomized, placebo-controlled, and double-blind. SETTING:Children were recruited at clinics in Kingston, Jamaica, and supplemented at home. SUBJECTS:Children selected were singletons aged 6-24 mo...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600509
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of moderate alcohol consumption on the acute phase proteins C-reactive protein and fibrinogen. DESIGN:Randomized, diet-controlled, cross-over study. SETTING:The study was performed at TNO Nutrition and Food Research, Zeist, The Netherlands. SUBJECTS:Ten middle-aged men and 10 postmen...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601459
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:Nutritional deficiency is an independent risk factor for mortality. Despite its clinical relevance, the prevalence in a primary care setting is poorly documented. We performed a systematic review of reported prevalence and clinical assessment of nutritional deficiency in general practice. METHODS:From MEDLIN...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1602178
更新日期:2005-08-01 00:00:00
abstract::The growth literature from developing countries is reviewed to assess the extent to which stunting, a phenomenon of early childhood, can be reversed in later childhood and adolescence. The potential for catch-up growth increases as maturation is delayed and the growth period is prolonged. However, maturational delays ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Living in socioeconomically disadvantaged neighbourhoods is associated with increased risk of a poor diet; however, the mechanisms underlying associations are not well understood. This study investigated whether selected healthy and unhealthy dietary behaviours are patterned by neighbourhood-socio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.174
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To describe the nutritional status of schoolchildren from a rural area of Tanzania, with a particular emphasis on older adolescents to determine the timing of the growth spurt and differences by sex. DESIGN:A cross-sectional survey using a randomly selected sample. SUBJECTS:Six thousand eight hundred and on...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600890
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:B vitamins and related enzymes involved in one-carbon metabolism are necessary for DNA replication, DNA repair and regulation of gene expression. Disruption of one-carbon mechanism may affect cancer risk. We investigated prospectively the relationship between dietary intakes of methionine, B vitam...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.157
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is a high prevalence of diabetes mellitus associated with insulin resistance in Indian adults, probably due to an inappropriately high accumulation of body fat at lower body mass indices (BMIs, kg/m(2)), as well as to a lower skeletal muscle mass. Although skeletal muscle is an important sit...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.32
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:In this study, we ascertained the relationship between resting energy expenditure (REE) obtained using two procedures: indirect calorimetry and from organ-tissue mass, calculated employing magnetic resonance imaging (MRI), and adult metabolic rate constants, in prepubertal children. Differences be...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0344-2
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To clarify the association of serum docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) levels with cognitive decline over 10 years. SUBJECTS/METHODS:This study was part of the National Institute for Longevity Sciences - Longitudinal Study of Aging, and was conducted with 232 male and 198 ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.264
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To assess the relationship of energy stress during pregnancy and lactation to maternal body stores in marginally nourished rural Bangladeshi women. SUBJECTS AND METHODS:Two-hundred and fifty-two women were followed from 5-7 months of pregnancy until 6 months postpartum. Energy intake was estimated during pre...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601514
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:The efficacy of zinc combined with vitamin A or multiple micronutrients in preventing diarrhoea is unclear in African countries with high prevalence of human immunodeficiency virus (HIV)-exposed children. Potential modifying factors, such as stunting, need to be addressed. The objective of this stu...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/ejcn.2008.78
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:It was determined whether a combination of Lactobacillus acidophilus (L. acidophilus) 74-2 and Bifidobacterium animalis subsp lactis DGCC 420 (B. lactis 420) affect the faecal microbiota as well as immunological parameters and blood lipids in healthy adults. DESIGN:A placebo-controlled, double-blinded, rando...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602761
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence of low body weight in Beijing pubertal girls and to establish the cut-off for body mass index (BMI) for underweight for Chinese pubertal girls. DESIGN:Cross-sectional study. SETTING:Three socioeconomic areas (rural, suburban and urban) in Beijing, China. SUBJECTS:Random sample...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601599
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Consumption of fruit and vegetables (F&V) is associated with a lower cardiovascular disease (CVD) risk. Smoking may affect the strength of this association. The objective of this study was to compare the relationship between the frequency of F&V intake and CVD risk in male current, former and neve...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.46
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVES:To study the effect of supplementation with an association of small physiological amounts of antioxidant nutrients upon biochemical parameters and indicators of oxidative stress and antioxidant enzymes. DESIGN:The study included a double-blind placebo-controlled design. SETTING:Nursing homes in different a...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVE:Several studies have found an inverse association between fish consumption and risk of dementia. The objective of this study was to describe the characteristics of older fish consumers, in order to identify potential confounders in this relationship. DESIGN:Cross-sectional analysis of the baseline data of a ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,多中心研究
doi:10.1038/sj.ejcn.1602145
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We investigated whether C-reactive protein (CRP) as indicator of acute inflammation is associated with maximal isometric handgrip strength in non-critically ill patients. SUBJECTS/METHODS:Handgrip strength was measured with Jamar dynamometer in 620 hospitalized patients (56.4±15.9 years old, 52.3...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.261
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To facilitate the development of practical public health advice targeted at childhood obesity (OB) prevention and make the intervention programs more effective, one has to promote the most protective habits and limit or modify the risk factors. The objective of the present study was to recognize t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.89
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Diet quality indices are increasingly used in nutrition epidemiology as dietary exposures in relation to health outcomes. However, literature on the long-term stability of these indices is limited. We aimed to assess the stability of the validated Framingham Nutritional Risk Score (FNRS) and its c...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2011.167
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The aim of the study was to describe a novel dietary assessment strategy based on two instruments complemented by information from an external population applied to estimate usual food intake in the large-scale multicenter German National Cohort (GNC). As proof of concept, we applied the assessmen...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0383-8
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To compare the efficacy of single versus multiple doses of plant sterols on circulating lipid level and cholesterol trafficking. SUBJECTS/METHODS:A randomized, placebo-controlled, three-phase (6 days/phase) crossover, supervised feeding trial was conducted in 19 subjects. Subjects were provided (...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2008.36
更新日期:2009-06-01 00:00:00
abstract::Nutrient intake was assessed for 15 long-stay elderly patients by 7-d weighed inventory. Analysis revealed neither significant day-to-day nor weekday/weekend variations for any studied nutrient except fibre. It would appear that acceptable indications of customary intake in this population can be achieved by measureme...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess how the glycaemic potency (blood glucose (BG)-raising potential) of breakfast is associated with cognitive function (CF) in school children, taking into account important confounders, including iron status, underlying physiological adaptations and socio-economic status. M...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.96
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Several factors affect the mental performance of children. The importance that parents attribute to food-related determinants, compared with genetic, socio-economic and school environment, was investigated. SUBJECTS/METHODS:Parents of school children (aged 4-11) were recruited through state prima...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.214
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We aimed to assess the effects on mild morbidity of a richly micronutrient-fortified complementary/replacement food given to Zambian infants aged 6-18 months. Previous results (The Chilenje Infant Growth, Nutrition and Infection Study Team, 2010) showed an increase in the rate of hospital referral...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2011.103
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk retinol concentration. METHODS:Fifty low income women were randomly assigned to a single oral dose of 209 micromol of Vitamin A or none at delivery. Maternal serum and breastmilk retinol levels and infant morbidity and ant...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600398
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVES:To examine the association between breastfeeding pattern and growth in the first year of life. METHODS:A cross-sectional survey was carried out on 349 mothers with infants <12 months in a rural and a semi-urban community in Mangochi district, Malawi. Data on socio-demographic characteristics, infant weight,...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.148
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To monitor the dietary intake of energy, macro- and micronutrients in asylum seeker children. DESIGN AND SETTING:Cross-sectional study in three asylum seeker centres in The Netherlands. SUBJECTS:Hundred and sixteen children 2-12 years old (86% of the study cohort) provided a dietary history. METHOD:The die...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602501
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To explore incidence and prevalence rates of nutritional deficiency in adults in general practice. METHODS:Six Dutch general practice research and registration networks supplied incidence and prevalence rates of nutritional deficiency by the International Classification of Primary Care (ICPC) or 'E-list' lab...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602195
更新日期:2005-08-01 00:00:00