Abstract：
:High serum antioxidant vitamins are increasingly being associated with reduced risk of coronary heart disease (CHD). Previous studies have not addressed the relationship between dietary antioxidant vitamins and risk of CHD although diet is a key factor which modifies blood antioxidant vitamin levels. In prospective studies, high-fibre diets have also been associated with reduced CHD incidence. In this analysis CHD-diagnosed, -undiagnosed and non-CHD controls were selected from 10,359 men and women aged 40-59 who participated in a cross-sectional study of CHD risk factors. Diet was assessed by food frequency questionnaire, odds ratios were adjusted for the classical CHD risk factors (+/- social class) and calculated relative to the first quintile for each vitamin and total fibre. The antioxidant vitamins were further combined in a principal component analysis and the odds ratios for undiagnosed and diagnosed CHD were again calculated. For undiagnosed CHD, risk was significantly lower in the highest quintiles of beta-carotene, fibre and vitamin C, E and A for men, but only lower for fibre in women. Opposite trends were observed in the odds ratios for vitamin C and E and fibre for male-diagnosed CHD which possibly indicates changes in diet as a result of diagnosis. Principal component analysis showed significantly reduced risk of undiagnosed CHD in the top three quintiles for men (odds ratios 0.66, 0.67 and 0.64; P less than 0.05 in each case). A similar trend occurred for women but was non-significant. The results suggest that high dietary intake of the antioxidant vitamins may reduce risk of CHD, particularly in men, and that fibre may be equally cardio-protective in both sexes.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Bolton-Smith C,Woodward M,Tunstall-Pedoe Hsubject
Has Abstractpub_date
1992-02-01 00:00:00pages
85-93issue
2eissn
0954-3007issn
1476-5640journal_volume
46pub_type
杂志文章abstract：OBJECTIVE:To assess the effect of cigarette smoking on the relationship between dietary intake and circulating levels of beta-carotene. DESIGN:A secondary analysis of data collected for the Diet and Nutritional Survey of British Adults by The Department of Health and The Ministry of Agriculture, Fisheries and Food; th...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:Several studies have found an inverse association between fish consumption and risk of dementia. The objective of this study was to describe the characteristics of older fish consumers, in order to identify potential confounders in this relationship. DESIGN:Cross-sectional analysis of the baseline data of a ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究
doi：10.1038/sj.ejcn.1602145
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:In international surveys of food consumption and nutrient intake, it is essential that the dietary data are comparable when different databases and calculation programs are used. The aim of the present analysis was to examine the comparability of nutrient intake data calculated on the basis of ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601639
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:To determine the content of glutamine in major food proteins. SUBJECTS/METHODS:We used a validated 131-food item food frequency questionnaire (FFQ) to identify the foods that contributed the most to protein intake among 70,356 women in the Nurses' Health Study (NHS, 1984). The content of glutamine and other...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.110
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To measure the relative effects of each of four phytosterol ester-enriched low-fat foods (bread, breakfast cereal, milk and yoghurt) on serum lipids, plasma phytosterols and carotenoids. DESIGN:: Three research centres undertook a randomised, incomplete crossover, single-blind study consisting of four treatm...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1038/sj.ejcn.1601837
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:We examined the relation between intake of natural dietary plant sterols and serum lipid concentrations in a free-living population. DESIGN, SETTING AND PARTICIPANTS:Cross-sectional population-based study of 22,256 men and women aged 39-79 y resident in Norfolk, UK, participating in the European Prospective ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601980
更新日期：2004-10-01 00:00:00
abstract：:Nonketotic hyperglycinemia (NKH) is a devastating inborn error of glycine metabolism caused by deficient activity of the glycine cleavage enzyme. Classically, patients present with lethargy, hypotonia, myoclonic jerks, transient respiratory depression in the first week of life and often progress to death. Surviving in...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0286-8
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:To assess the effects in humans of regular ingestion of black tea on haemostasis-related variables and cell adhesion molecules. DESIGN:Twenty-two subjects were recruited from the general population to a randomised-controlled crossover study. Subjects stopped drinking tea, apart from that provided, for the du...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601231
更新日期：2001-10-01 00:00:00
abstract：:Sodium intake is assessed using 24 h urinary excretion; it is important to ensure urine collections are complete. This can be validated by monitoring urinary excretion of p-aminobenzoic acid (PABA) administered in tablet form at intervals during the urine collection. Unavoidable change of PABA tablet supplier and anal...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0195-x
更新日期：2018-08-01 00:00:00
abstract：:The relationship between diet and attained height was studied in children and adolescents in Southern California. Diet pattern was determined from an extensive food frequency questionnaire in 1765 Caucasian children of 7-18 years, attending state schools (452 m and 443 f) and Seventh-day Adventist schools (427 m and 4...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Body composition assessment by computed tomography (CT) is increasingly used for diagnostic and prognostic purposes in various patient groups. This study aimed to compare the reliability and validity of a newly in-house developed segmentation software VikingSlice against a commercial software (Sli...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0110-5
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:The purpose of the present study was to compare the nutrient intake and the nutritional status between German middle-class alcohol consumers and non-drinkers. DESIGN:Cross-sectional study using patients with different stages of alcoholic liver disease (ALD) and healthy volunteers. SETTING:Southern Germany. ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601557
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVES:To compare dietary fat intake, the accuracy of individuals' awareness about their fat intake, and sociodemographic and psychosocial correlates of awareness, in Dutch and American samples of employed adults. A discrepancy between objective dietary intake data and subjective self-evaluation of dietary fat cons...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600442
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of moderate alcohol consumption on the acute phase proteins C-reactive protein and fibrinogen. DESIGN:Randomized, diet-controlled, cross-over study. SETTING:The study was performed at TNO Nutrition and Food Research, Zeist, The Netherlands. SUBJECTS:Ten middle-aged men and 10 postmen...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601459
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is convincing evidence that a high dietary fiber intake may lower the risk of coronary heart disease. However, the role of fiber in the prevention of stroke is unclear. We examined the associations of dietary fiber and fiber-rich food intake with risk of stroke within the Alpha-tocopherol, B...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.16
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Consumption of fruit and vegetables (F&V) is associated with a lower cardiovascular disease (CVD) risk. Smoking may affect the strength of this association. The objective of this study was to compare the relationship between the frequency of F&V intake and CVD risk in male current, former and neve...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.46
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To describe the secular trends in the prevalence rates of iron-deficiency anemia (IDA) in infants in Israel, identify population group differences and assess the effectiveness of the 1985 Public Health directives on iron supplementation and avoidance of cow's milk in the first year of life. DESIGN:A systemat...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601119
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Several factors affect the mental performance of children. The importance that parents attribute to food-related determinants, compared with genetic, socio-economic and school environment, was investigated. SUBJECTS/METHODS:Parents of school children (aged 4-11) were recruited through state prima...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2013.214
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To assess the effects of smoking on serum lipoprotein levels taking into account current nutritional intakes. DESIGN:Case-control study comparing smokers and non-smokers. SETTING:Ambulatory subjects of the Urban Community of Lille examined at home or at the Health Care Center. SUBJECTS:Men, between 45 and ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Observational studies document the inverse relationship between cardiovascular disease (CVD) and moderate alcohol intake. However, the causal role for alcohol in cardioprotection remains uncertain as such protection may be caused by confounders and misclassification. The aim of our study was to ev...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.61
更新日期：2010-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The available evidence from randomised controlled trials suggests that vitamin B12 supplementation does not improve neurologic function in older people with marginal but not deficient Vitamin B12 status. This secondary analysis used data from the Older People and Enhanced Neurological function (OP...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/ejcn.2017.7
更新日期：2017-10-01 00:00:00
abstract：:This study examined the association of dietary calcium intake with incident type 2 diabetes by a meta-analysis and explored the potential confounding by magnesium. Potential studies were identified by searching the PubMed database in September 2011. Prospective cohort studies that reported relative risks (RR) with 95%...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,meta分析
doi：10.1038/ejcn.2012.5
更新日期：2012-03-01 00:00:00
abstract：:As type 2 diabetes mellitus (DM2), obesity and sedentary lifestyles are increasing in developing countries, this observational study investigated the role of physical activity on DM2 in Jamaica. Anthropometry, body composition (by bioelectrical impedance analysis) and glucose tolerance status was assessed in 722 adult...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602011
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:The EURRECA (EURopean micronutrient RECommendations Aligned) Network of Excellence collated current micronutrient recommendations. A user-friendly tool, Nutri-RecQuest, was developed to allow access to the collated data and to create a database source for use in other nutritional software tools. METHODS:Rec...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.60
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to assess the major dietary patterns of two age cohorts of women, to determine to the extent to which the dietary patterns differ between the cohorts and to assess whether they vary according to sociodemographic and behavioural characteristics and patterns of nutrient intake. METHOD...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2010.121
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Diet can affect the acid-base status depending on the balance between the intake of acid-inducing foods and base-inducing foods. The purpose of this study was to estimate the dietary acid load and evaluate its association with serum bicarbonate in patients with stages 3 and 4 chronic kidney diseas...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-0689-1
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:To compare the most commonly used equations to predict body fatness from skinfold thickness, in male and female adolescents, with dual-energy X-ray absorptiometry (DXA) as a reference method of fatness measurement. DESIGN:Cross-sectional nutrition survey. SETTING:General adolescent population from Zaragoza ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602226
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:To investigate the prevalence of low body weight in Beijing pubertal girls and to establish the cut-off for body mass index (BMI) for underweight for Chinese pubertal girls. DESIGN:Cross-sectional study. SETTING:Three socioeconomic areas (rural, suburban and urban) in Beijing, China. SUBJECTS:Random sample...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601599
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:To explore whether mothers' lifetime experiences with their own weight status and related cognitive and affective factors influence child feeding behavior. SUBJECTS/METHODS:Overweight mothers (N = 221) of 4-5 year olds recalled their weight at four time points, and were grouped into weight histor...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-017-0071-0
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:We analysed at what age parents start complementary food in very low birth weight infants, determined risk factors for early introduction of complementary food (post-term age) and analysed whether the age at introduction of complementary food influences height or weight at 2 years of age. SUBJECT...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2015.54
更新日期：2015-06-01 00:00:00
