Abstract：
OBJECTIVE:We examined the relation between intake of natural dietary plant sterols and serum lipid concentrations in a free-living population. DESIGN, SETTING AND PARTICIPANTS:Cross-sectional population-based study of 22,256 men and women aged 39-79 y resident in Norfolk, UK, participating in the European Prospective Investigation into Cancer (EPIC-Norfolk). MAIN EXPOSURE AND OUTCOME MEASURES: Plant sterol intake from foods and concentrations of blood lipids. RESULTS:Mean concentrations of total cholesterol and low-density lipoprotein cholesterol, adjusted for age, body mass index and total energy intake, decreased with increasing plant sterol intake in men and women. Mean total serum cholesterol concentration for men in the highest fifth of plant sterol intake (mean intake 463 mg daily) was 0.25 mmol/l lower and for low-density lipoprotein cholesterol 0.14 mmol/l lower than those in the lowest fifth of plant sterol consumption (mean intake 178 mg daily); the corresponding figures in women were 0.15 and 0.13 mmol/l. After adjusting for saturated fat and fibre intakes, the results for total cholesterol and low-density lipoprotein cholesterol were similar, although the strength of the association was slightly reduced. CONCLUSIONS:In a free-living population, a high intake of plant sterols is inversely associated with lower concentrations of total and low-density lipoprotein serum cholesterol. The plant sterol content of foods may partly explain diet-related effects on serum cholesterol concentration.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Andersson SW,Skinner J,Ellegård L,Welch AA,Bingham S,Mulligan A,Andersson H,Khaw KTdoi
10.1038/sj.ejcn.1601980subject
Has Abstractpub_date
2004-10-01 00:00:00pages
1378-85issue
10eissn
0954-3007issn
1476-5640pii
1601980journal_volume
58pub_type
杂志文章abstract：BACKGROUND/OBJECTIVES:The aim of the study was to describe a novel dietary assessment strategy based on two instruments complemented by information from an external population applied to estimate usual food intake in the large-scale multicenter German National Cohort (GNC). As proof of concept, we applied the assessmen...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-018-0383-8
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To investigate the prevalence of low body weight in Beijing pubertal girls and to establish the cut-off for body mass index (BMI) for underweight for Chinese pubertal girls. DESIGN:Cross-sectional study. SETTING:Three socioeconomic areas (rural, suburban and urban) in Beijing, China. SUBJECTS:Random sample...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1601599
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Famine exposure is a potential risk factor for adverse cardiometabolic health. However, the relationship between famine exposure during early life and carotid plaque in adulthood remains unclear. Therefore, the aim was to investigate the relationship between famine exposure during early life and the risks fo...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00756-7
更新日期：2020-09-16 00:00:00
abstract：OBJECTIVE:To assess the effects of dietary supplementation using two isomeric blends of conjugated linoleic acid (CLA) on immune function in healthy human volunteers. DESIGN:Double-blind, randomised, placebo-controlled intervention trial. SUBJECTS AND INTERVENTION:A total of 55 healthy volunteers (n=20 males, n=35 fe...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602132
更新日期：2005-06-01 00:00:00
abstract：:Adult (primary) lactose malabsorption is practically universal in Africans of Bantu and San ('Bushmen') stock. Recent environmental changes, especially in rural areas, have exacerbated rates of malnutrition in hospital patients belonging to these groups. In order to assess the advisability of using milk as a nutrition...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVE:Total body water can be calculated using stable isotopes by two alternative approaches known as the plateau method and the back extrapolation method. These methods treat the isotopic data in different ways and consequently do not necessarily produce identical values for total body water. Total body water was ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To validate selected nutrients assessed by the food frequency questionnaire (FFQ) used in the Harvard cohort studies in an African-American group. DESIGN:Blood aliquots were pooled for each decile of intake of two carotenoids and alpha tocopherol as measured by FFQ. These pooled samples were analyzed for nut...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602641
更新日期：2007-11-01 00:00:00
abstract：:Despite the fact that both thiamine deficiency (TD) and Wernicke encephalopathy (WE) have been observed to some degree in cancer patients, such cases of TD and/or WE reported to date have all been diagnosed after the initiation of treatment. We here report a case of TD that presented without the commonly accepted tria...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/s41430-020-00735-y
更新日期：2020-09-07 00:00:00
abstract：BACKGROUND/OBJECTIVES:Sarcopenia and sarcopenic obesity (SO) are geriatric syndromes leading to physical disability, poor quality of life and death. The aim of this study was to investigate the prevalence of sarcopenia and SO in nursing homes in Turkey and to define local disparities for diagnosing sarcopenia and SO. ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究
doi：10.1038/ejcn.2014.15
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:To describe drinking patterns among individuals who prefer drinking wine, beer or spirits. DESIGN:Cross-sectional study obtaining detailed information on intake of wine, beer and spirits and on frequency of alcohol intake. Adjustment for gender, age, smoking habits, educational attainment and body mass index...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600919
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVE:To assess the usefulness of fat-free mass (FFM) as an index of total body protein (TBPr) status in continuous ambulatory peritoneal dialysis (CAPD) patients. DESIGN:TBPr was measured by in vivo neutron activation analysis (IVNAA) and expressed as a standardised protein index (PI). FFM was estimated by dual e...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVE:To collect (i) baseline data and (ii) execute a large multicentre study examining the effect of trans alpha-linolenic acid on its incorporation into plasma lipids and on risk factors for coronary heart disease. DESIGN:Male volunteers were recruited and the habitual diet assessed by a 4-d weighed record. Fatt...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1600903
更新日期：2000-02-01 00:00:00
abstract：:The present study tested the hypotheses that: (a) individual body composition estimates obtained with the Durnin-Womersley (D-W) equations have low validity in certain populations in developing countries; (b) there exists a poor relationship between the body mass index (BMI) and body composition estimates (fat mass (B...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVE:To define the cellular basis for immune enhancement by a probiotic lactic acid bacteria strain (Bifidobacterium lactis HN019); and to determine whether immune enhancement can be optimized by delivery in oligosaccharide-enriched low-fat milk. DESIGN:A double-blind, three-stage before-and-after intervention tr...
journal_title：European journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1601093
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVE:To determine the origin of the poor digestibility of banana starch granules in the human small intestine. DESIGN:The subjects received the same experimental meal. SETTING:Nutrition Research Unit, Laënnec Hospital, CHU, Nantes. SUBJECTS:Six healthy young subjects. INTERVENTIONS:The digestion of raw green b...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：:This study examined the association of dietary calcium intake with incident type 2 diabetes by a meta-analysis and explored the potential confounding by magnesium. Potential studies were identified by searching the PubMed database in September 2011. Prospective cohort studies that reported relative risks (RR) with 95%...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,meta分析
doi：10.1038/ejcn.2012.5
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Observational studies have suggested low serum levels of vitamin B12 or folate to be risk factors of depression and anxiety. However, these results may be biased by confounding and reverse causation. Mendelian randomization studies are not subject to these limitations. The aim was to examine the a...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2017.97
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:The aim was to examine the concordance of diet with the recommended cholesterol lowering diet in Coronary Heart Disease (CHD) patients receiving usual care. DESIGN:CHD patients were selected for a survey from hospital records at least six months after hospitalization. Four patient groups divided according to...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600549
更新日期：1998-04-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between the common cold and vitamin C supplementation. DESIGN:A double-blind, 5-year randomized controlled trial. SETTING:A village in Akita prefecture, one of the regions in Japan with the highest mortality from gastric cancer. SUBJECTS:Participants in annual screening prog...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602261
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Growth parameters during infancy and early childhood might predict adipokine levels later in life. This study investigates the association between peak growth velocities, body mass index (BMI) and age at adiposity rebound (AR), with leptin and adiponectin levels at age 10 years. SUBJECTS/METHODS:...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2013.213
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:To describe the intake of vitamins thiamine (B1), riboflavin (B2), B6 (pyridoxine), B12 (cobalamine) and C (ascorbic acid) and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. METHODS:Between 1995 and 2000, 36...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2009.78
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:To examine the effect of acute fluid consumption on measures of impedance and percent body fat (%BF) using a common leg-to-leg bioelectrical impedance analyzer system. DESIGN:Cross-sectional design with treatment order determined using a counterbalanced assignment. SETTING:University laboratory. SUBJECTS:I...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/sj.ejcn.1602282
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:It is unknown if a specific fatty-acid composition influences the development of Alzheimer's disease (AD). Nutrition is a possible target for prevention of dementia and especially omega-3-based fatty acids (n-3 FAs) have previously been suggested to be beneficial for cognition. The objective was t...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/ejcn.2012.63
更新日期：2012-08-01 00:00:00
abstract：OBJECTIVE:To calculate intra-cluster and intra-household design effects and intra-class correlation coefficients for dietary nutrients obtained from a 24 h record-assisted recall. DESIGN:Children were recruited using clustered probability sampling. Randomly selected starting-point addresses were obtained with probabil...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602618
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVE:To assess total daily energy expenditure (TDEE) and patterns of physical activity among Swedish male and female adolescents and to relate the amount and intensity of physical activity to existing recommendations (energy expenditure equal to or above 12.4 kJ/kg/day or accumulation of 30 min/day in moderate phy...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600918
更新日期：2000-03-01 00:00:00
abstract：OBJECTIVES:Study 1: To establish the validity of scores on Nutrition Screening Tool for Every Preschooler (NutriSTEP), a community-based parent-administered screening tool for assessing nutrition risk, by comparing scores to an expert rating. Study 2: To demonstrate test-retest reliability of NutriSTEP. SUBJECTS/METHO...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1602780
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the use of a self-administered quantitative food frequency questionnaire (QFFQ) in a national dietary survey concerning (a) response rates with different distribution methods and reward; (b) degree of underreporting of energy intake; (c) reproducibility of the QFFQ; and (d) seasonal variation on ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：10.1038/sj.ejcn.1600410
更新日期：1997-06-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The majority of hospital outpatients with undernutrition is unrecognized, and therefore untreated. There is a need for an easy and valid screening tool to detect undernutrition in this setting. The aim of this study was to determine the diagnostic accuracy of the MUST (Malnutrition Universal Scree...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,多中心研究
doi：10.1038/ejcn.2013.85
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Children born to human immunodeficiency virus (HIV)-infected women are susceptible to undernutrition, but modifiable risk factors and the time course of the development of undernutrition have not been well characterized. The objective of this study was to identify maternal, socioeconomic and child...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1038/ejcn.2012.136
更新日期：2012-11-01 00:00:00
abstract：OBJECTIVE:To assess the effects of smoking on serum lipoprotein levels taking into account current nutritional intakes. DESIGN:Case-control study comparing smokers and non-smokers. SETTING:Ambulatory subjects of the Urban Community of Lille examined at home or at the Health Care Center. SUBJECTS:Men, between 45 and ...
journal_title：European journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
