Abstract:
OBJECTIVE:We investigated whether there was a growth or morbidity response to zinc supplementation. DESIGN:The study was randomized, placebo-controlled, and double-blind. SETTING:Children were recruited at clinics in Kingston, Jamaica, and supplemented at home. SUBJECTS:Children selected were singletons aged 6-24 months, and stunted (< -2.0 s.d. length for age, NCHS references). They were stratified by sex and age and randomly assigned to receive zinc supplement (n = 31) or placebo (n = 30). Four children were excluded because of hospitalization; all others had all measurements. Adequately nourished children (n = 24) were recruited from a well-baby clinic. INTERVENTIONS:The supplement provided 5 mg elemental zinc in a syrup daily for 12 weeks; the placebo comprised the syrup only. MAIN OUTCOME MEASURES:Caretakers were interviewed to obtain social background data, number of clinic visits and hospitalizations. Anthropometric measurements were done on enrolment, and after 6 weeks, 12 weeks and 12 months. Children's health was determined by weekly questionnaire to caretakers of the undernourished groups during the supplementation period. RESULTS:The supplemented and placebo groups were similar on enrolment. The adequately nourished children were from significantly better socio-economic circumstances. Mean initial hair zinc content was 5.5 +/- 4.8 mumol/g (supplemented group) and 6.7 +/- 12.1 mumol/g (placebo)(n.s.). Regression analyses showed that there were no significant effects of supplementation on length, height or head circumference, nor on the incidence of any morbidity symptom. Mean duration of the episodes was significantly shorter for skin rashes in the supplemented group compared with the control group (ANCOVA, P = 0.02), and longer for vomiting (P = 0.02). The incidence of hospitalization was significantly greater in the control group (Fisher's exact test, P = 0.02). CONCLUSIONS:Zinc supplementation reduced the hospitalizations which probably reflect severity of morbidity, but did not improve growth.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Meeks Gardner J,Witter MM,Ramdath DDdoi
10.1038/sj.ejcn.1600509subject
Has Abstractpub_date
1998-01-01 00:00:00pages
34-9issue
1eissn
0954-3007issn
1476-5640journal_volume
52pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:To describe dietary carbohydrate intakes and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. METHODS:Between 1995 and 2000, 36 034 subjects, aged between 35-74 years, were administered a standardized, 24-h die...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.74
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Older people are becoming an increasingly important proportion of the populations of developing countries, yet little information exists on their nutritional status or social conditions. OBJECTIVE:To assess the nutritional status of older people in rural Malawi. DESIGN:Cross-sectional study. SETTING:Lilon...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600617
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:To assess the genetic and nongenetic correlates of circulating measures of vitamins K and D status in a community-based sample of men and women. SUBJECTS/METHODS:A cross-sectional study of 1762 participants of the Framingham Offspring Study (919 women; mean age 59 years). Vitamin K status was measured as pla...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602959
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The prevalence of gestational diabetes mellitus (GDM) is increasing worldwide. GDM may be prevented by improving the diets of pregnant women. The objective of this study was to evaluate the effect of dietary counselling on the diets of pregnant women at GDM risk. SUBJECTS/METHODS:This study was a...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2015.205
更新日期:2016-08-01 00:00:00
abstract::This study examined whether the association of household income with fresh fruit and vegetable consumption varies by the level of education. Data were derived from mail surveys carried out during 2000-2002 among 40- to 60-year-old employees of the City of Helsinki (n=8960, response rate 67%). Education was categorized...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.155
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To explore the associations between serum concentrations of vitamin D (25(OH)D) and all-cause mortality among US adults defined by lung function (LF) status, particularly among adults with obstructive LF (OLF). METHODS:Data from 10,795 adults aged 20-79 years (685 with restrictive LF (RLF) and 1309 with OLF)...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.162
更新日期:2015-05-01 00:00:00
abstract::Bioelectrical impedance analysis is an extremely popular method for assessment of body composition. Despite its wide-spread use over the past thirty years, its accuracy and clinical value is still questioned. Most frequently, criticisms focus on its purported poor absolute accuracy and that different impedance analyse...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/s41430-018-0335-3
更新日期:2019-02-01 00:00:00
abstract::Adult (primary) lactose malabsorption is practically universal in Africans of Bantu and San ('Bushmen') stock. Recent environmental changes, especially in rural areas, have exacerbated rates of malnutrition in hospital patients belonging to these groups. In order to assess the advisability of using milk as a nutrition...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Changes in plasma insulin and glucose concentrations before and after feeding were measured in six female subjects (post-obese) who had regained a normal body mass after a history of severe obesity (mean weight loss, 37.1 +/- 2.6 kg). The responses of the post-obese group were compared with a group of weight- and age-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract:OBJECTIVE:The validation of dietary assessment methods is critical in the evaluation of the relation between dietary intake and health. The aim of this study was to assess the validity of a food frequency questionnaire by comparing energy intake with energy expenditure measured with the doubly labelled water method. D...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601519
更新日期:2003-02-01 00:00:00
abstract::We studied effects of dose and treatment duration during low-dose iron supplementation in premenopausal, non-pregnant women, with initial serum ferritin and haemoglobin concentrations < 20 micrograms x l-1 and > or = 120 g x l-1, respectively. The study was randomized, double-blind and placebo-controlled. Three groups...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Consumption of n-3 polyunsaturated fatty acids (PUFA) has a favourable impact on inflammation and cardiovascular disease. However, the Western diet is characterized by a low n-3 PUFA intake and an imbalance in the n-6/n-3 PUFA ratio. Study the effect 10-week of diet modification to decrease the n-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602857
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:To compare validation of reported dietary intakes from weighed records against urinary nitrogen excretion and energy expenditure measured by DLW, and to examine the utility of the Goldberg cut-off for EI:BMR in the identification of under-reporters. DESIGN:Energy (EI) and nitrogen (protein) intake (NI) were...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600425
更新日期:1997-06-01 00:00:00
abstract::It has been suggested that energy requirements are either proportional to the BMR (FAO/WHO/UNU, 1985) or to body weight (WHO, 1973). The present analysis sought to distinguish between these two possibilities by determining whether, in rural Gambian women, energy expenditure was more nearly proportional to the BMR or t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:
更新日期:1988-11-01 00:00:00
abstract::We previously detected that ~50% of kidney transplant patients (KTPs) present sarcopenia using the first European Working Group on Sarcopenia in Older People (EWGSOP1) consensus. Our aim was to evaluate the agreement between the sarcopenia diagnosis using EWGSOP1 and the new consensus (EWGSOP2) in KTPs. A cross-sectio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-019-0535-5
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of low and marginal iodine intake and urinary iodine excretion among adults in the Netherlands and to investigate determinants of urinary iodine excretion. DESIGN AND SUBJECTS:The study population consisted of 444 people aged 20-79 y, balanced for sex and 10 y age classes with an ove...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract::A cross-sectional study of children in West Kalimantan, Indonesia, was conducted to examine the relationship between malnutrition history, child IQ, school attendance, socioeconomic status, parental education and parental IQ. In unadjusted analyses, severely stunted children had significantly lower IQ scores than mild...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602103
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To derive dietary patterns and examine their longitudinal associations with sociodemographic and lifestyle factors in the Tasmanian Older Adult Cohort. SUBJECTS/METHODS:This is a corrected analysis of a retracted paper. We followed 1098 adults aged ≥50 years for 5 years. Dietary intake was assess...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00802-4
更新日期:2020-11-16 00:00:00
abstract::In this issue we would like to thank all those listed below for taking the time to review for the European Journal of Clinical Nutrition in 2019-your generosity is much appreciated and we hope your association with the journal continues in the future. ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0589-4
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:Pregnant women in developing countries might be at risk of trace element deficiencies. These deficiencies could have deleterious effects on fetus. Therefore, serum trace elements were determined at delivery in Zairian mothers and their newborns. DESIGN:Prospective study. SETTING:Maternity ward of Kinshasa ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Little is known about whether waist circumference (WC) has increased disproportionately relative to body mass index (BMI) around the world. SUBJECTS/METHODS:Data came from the US National Health and Nutrition Examination Survey (1988-1994 and 2007-2010), Health Survey for England (1992-1993 and 2...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.71
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To determine if consumption of yogurt containing a high dose of probiotic (1×10(10) colony-forming unit per 100 ml), Bifidobacterium animalis subsp. lactis (B. lactis), decreases absences in children 2-4 years attending daycare/school centers. SUBJECTS/METHODS:We conducted a double-blinded, rando...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2010.290
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To examine the effect of low-dose fish oil supplementation on specific growth factors, purported to play a central role in lesion formation, and also on the total growth factor activity of serum, as assessed by the induction of DNA synthesis in cultured human arterial smooth muscle cells. DESIGN:Randomized p...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601076
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We evaluated the agreement of air displacement plethysmography (ADP) and bioelectrical impedance analysis (BIA) with dual-energy X-ray absorptiometry (DXA) for the assessment of percent fat mass (%FM) in morbidly obese women. SUBJECTS/METHODS:Fifty-seven women aged 19-55 years and with a body mas...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.159
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Observational studies document the inverse relationship between cardiovascular disease (CVD) and moderate alcohol intake. However, the causal role for alcohol in cardioprotection remains uncertain as such protection may be caused by confounders and misclassification. The aim of our study was to ev...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.61
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To assess vitamin D status in women and their children aged 4-5 years in Northern Jordan during summer. DESIGN:A cross-sectional study in which 93 mother-child dyads volunteered through local community centers between June and July 2007. Anthropometric measurements were performed and information on socioecon...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.99
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of irregular meal frequency on circulating lipids, insulin, glucose and uric acid concentrations which are known cardiovascular risk factors. DESIGN:A randomised crossover dietary intervention study. SETTING:Nottingham, UK--Healthy free-living women. SUBJECTS:A total of nine lean ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601935
更新日期:2004-07-01 00:00:00
abstract::This study examined the association of dietary calcium intake with incident type 2 diabetes by a meta-analysis and explored the potential confounding by magnesium. Potential studies were identified by searching the PubMed database in September 2011. Prospective cohort studies that reported relative risks (RR) with 95%...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,meta分析
doi:10.1038/ejcn.2012.5
更新日期:2012-03-01 00:00:00
abstract::The purpose of this study was to investigate the relationship between dietary antioxidant intake and the risk of subarachnoid hemorrhage (SAH) in a case-control study. An antioxidant intake score was calculated for individual values for each food group (soy products, green yellow-vegetables, fruits, boiled rice and te...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602669
更新日期:2007-09-01 00:00:00
abstract::The success of the Human Genome Project and the spectacular development of broad genomics tools have catalyzed a new era in both medicine and nutrition. The terms pharmacogenomics and nutrigenomics are relatively new. Both have grown out of their genetic forbears as large-scale genomics technologies have been develope...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1602590
更新日期:2007-05-01 00:00:00