Abstract:
:The present study was conducted to test the efficacy of fibre supplementation for hypercholesterolaemia in subjects from the desert Nomads. Ten males (53 +/- 8 years of age) participated in this study which consisted of three phases: baseline-1 period (2 weeks) in which subjects were on their normal, habitual dietary intake, followed by a period of fibre supplementation (5 weeks) in which subjects were supplemented with 26 g fibre/d, and baseline-2 period (4 weeks) in which fibre supplement was withdrawn. Fibre supplementation resulted in a significant decrease in levels of total serum cholesterol (10 per cent decrease, P less than 0.005 during the second week; and 13.4 per cent decrease, P less than 0.0005 during the fifth week) and LDL-cholesterol (14.3 per cent decrease, P less than 0.01 during the second week; and 16.8 per cent decrease, P less than 0.005 during the fifth week. The LDL/HDL ratio dropped 5.2 per cent (P less than 0.005) during the second week and 10.4 per cent (P less than 0.0001) during the fifth week of the fibre supplementation period. Concentrations of serum triglycerides decreased 4.8 per cent (not significant) during the second week and 9.5 per cent (P less than 0.01) during the fifth week. Daily intake of nutrients, body weight, and HDL-cholesterol levels did not change significantly. We conclude that, in populations such as the desert Nomads, where dietary manipulation and/or therapeutic options are quite limited, fibre supplementation may provide an alternative and effective therapy for the control of hypercholesterolaemia.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Cossack ZT,Musaiger AOsubject
Has Abstractpub_date
1991-02-01 00:00:00pages
105-10issue
2eissn
0954-3007issn
1476-5640journal_volume
45pub_type
杂志文章abstract::The present study tested the hypotheses that: (a) individual body composition estimates obtained with the Durnin-Womersley (D-W) equations have low validity in certain populations in developing countries; (b) there exists a poor relationship between the body mass index (BMI) and body composition estimates (fat mass (B...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Urinary and plasma indices are utilized to assess whole-body water balance in healthy adults, whereas the urine-to-plasma osmolality ratio (Uosm:Posm) rarely is. To explore the efficacy of Uosm:Posm as a hydration biomarker, diet records of 120 college women were analyzed (beverage water+food wate...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.79
更新日期:2013-09-01 00:00:00
abstract::Urea kinetics was measured in a single woman on five occasions over four years by the prime/intermittent oral-dose method with [15N15N]-urea. On a nitrogen intake of 231 +/- 24 mg/kg/day, urea production was 198 +/- 22 mg/kg/day, with the urinary excretion of urea being 143 +/- 25 mg/kg/day. Urea hydrolysis and salvag...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:There is scarce evidence of how certain eating behaviours compromise the compliance with dietary guidelines and weight status in school-aged children. This study aims to evaluate the association of children's problematic eating behaviours with food quality and body mass index at 7 years of age. S...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0169-z
更新日期:2019-04-01 00:00:00
abstract::The purpose of this study was to investigate the relationship between dietary antioxidant intake and the risk of subarachnoid hemorrhage (SAH) in a case-control study. An antioxidant intake score was calculated for individual values for each food group (soy products, green yellow-vegetables, fruits, boiled rice and te...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602669
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To describe dietary carbohydrate intakes and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. METHODS:Between 1995 and 2000, 36 034 subjects, aged between 35-74 years, were administered a standardized, 24-h die...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2009.74
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:We hypothesized that very low birth weight (VLBW) infants have reduced serum and red blood cell (RBC) selenium (Se) at birth, which decrease further with current nutrition and are associated with chronic lung disease and septicaemia. DESIGN:We studied Se intake, concentration in serum and RBCs and glutathion...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602715
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:To examine seasonality of 25-hydroxyvitamin D (25OH-D) levels in British preschool children and the effect of vitamin D supplementation on this. DESIGN:The National Diet and Nutrition Survey of children aged 1.5 4.5 y in Britain during 1992-3 measured dietary intakes and blood status indices, including thos...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600697
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:To determine the effect of iron supplementation on iron status and endurance capacity. DESIGN:Randomized, double-blind iron supplementation. SETTING:University of Missouri-Columbia and surrounding community. SUBJECTS:Twenty iron-deficient (serum ferritin, sFer<16 microg/l; serum transferrin receptor, sTfR>...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602479
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Iodine deficiency is a serious public health problem worldwide which is associated with mental retardation and cretinism. In view of a high incidence of transient neonatal hypothyroidism and a relatively high mean cord blood thyrotropin (TSH) concentration, a pilot study was carried out to analyse the urine i...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract:OBJECTIVE:To examine the influence of intense sweetener consumption on nutrient intakes in insulin dependent diabetics compared to controls. DESIGN:Case-control food consumption survey. SETTING:Dietary data were collected from individuals in Ireland between 1998 and 1999. SUBJECTS:Diabetics were recruited through di...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601969
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of irregular meal frequency on circulating lipids, insulin, glucose and uric acid concentrations which are known cardiovascular risk factors. DESIGN:A randomised crossover dietary intervention study. SETTING:Nottingham, UK--Healthy free-living women. SUBJECTS:A total of nine lean ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601935
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Health education and regulatory measures may contribute to lower population salt intake. Therefore, we aimed to describe knowledge and behaviors related to salt intake in Mozambique. SUBJECTS/METHODS:A cross-sectional evaluation of a representative sample of the population aged 15-64 years (n = 3...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0125-y
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Anorexia or lack of appetite is common in chronic obstructive pulmonary disease (COPD) and may be caused or augmented by several symptoms affecting appetite and eating. We aimed to investigate and quantify the extent of nutrition impact symptoms (NIS) in patients with COPD and to explore relations...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.76
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The roles of vitamin B12 and homocysteine concentration in depression are not clear. We investigated cross-sectional and prospective associations of serum vitamin B12 and plasma homocysteine with depressive symptoms in Dutch older adults. SUBJECTS/METHODS:In the Longitudinal Aging Study Amsterdam...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.224
更新日期:2017-04-01 00:00:00
abstract::To study the role of diet, 197 patients of essential hypertension were randomized to either experimental diet (group A, 97 cases) or normal diet (group B, 100 cases) with diuretics given to both the groups. The age varied between 25 and 65 years and 154 were males. The study diet included a significantly higher conten...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-04-01 00:00:00
abstract::Food fortification can deliver essential micronutrients to large population segments without modifications in consumption pattern, suggesting that fortified foods may be formulated for populations at risk for fragility fractures. This scoping review determined the extent to which randomized controlled studies have bee...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2016.42
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:We examined the relation between intake of natural dietary plant sterols and serum lipid concentrations in a free-living population. DESIGN, SETTING AND PARTICIPANTS:Cross-sectional population-based study of 22,256 men and women aged 39-79 y resident in Norfolk, UK, participating in the European Prospective ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601980
更新日期:2004-10-01 00:00:00
abstract::Pregnancy and the first two years of life are periods of rapid growth and yet the knowledge of requirements for protein and dietary indispensable amino acids is very limited. The development of carbon oxidation methods opens the way to studies that should fill these important gaps in knowledge. ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.297
更新日期:2014-03-01 00:00:00
abstract::Alcohol-induced hypoglycaemia is a well-known phenomenon in insulin-treated diabetic subjects. Less attention has been paid to the impact of alcohol on blood glucose and insulin responses in non-insulin dependent diabetic subjects. The aim of this study was to investigate the acute metabolic effects of different alcoh...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-09-01 00:00:00
abstract::Efforts to combat nutrient deficiencies have centered on supplemental nutrient administration and addition of selected nutrients to the food chain in the form of food fortification. Over the past several decades, and as the association between diet and chronic diseases became apparent, supplementation and fortificatio...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601803
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Few studies in Latin American paediatric populations have differentiated fat deposits in specific areas, such as intra-abdominal fat (IAF) and subcutaneous abdominal fat (SAF). Research in diverse populations is needed, as patterns of fat accumulation vary by ethnicity. The aim of this study was to...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2017.28
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Consumption of n-3 polyunsaturated fatty acids (PUFA) has a favourable impact on inflammation and cardiovascular disease. However, the Western diet is characterized by a low n-3 PUFA intake and an imbalance in the n-6/n-3 PUFA ratio. Study the effect 10-week of diet modification to decrease the n-...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602857
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:This paper examines whether diet had changed at platforms in the Norwegian sector of the North Sea between 1985 and 1993 and if this was caused by nutrition promotive activities, including the use of a health handbook (HHB). DESIGN:The report is based on two cross-sectional surveys, one in 1985 and one in 19...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:In most populations the prevalence of obesity is greater in women than in men; however, the magnitude of the difference between the sexes varies significantly by country. We considered the role of gender inequality in explaining these disparities. SUBJECTS/METHODS:We undertook an ecological analy...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.86
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:In view of the ongoing debate on "chronic malnutrition" and the concept of "stunting" as "a better measure than underweight of the cumulative effects of undernutrition and infection (WHO)", we translate, briefly comment and re-publish three seminal historic papers on catch-up growth following re-feeding afte...
journal_title:European journal of clinical nutrition
pub_type: 历史文章,杂志文章,评审
doi:10.1038/s41430-018-0274-z
更新日期:2018-12-01 00:00:00
abstract::The relationship between diet and attained height was studied in children and adolescents in Southern California. Diet pattern was determined from an extensive food frequency questionnaire in 1765 Caucasian children of 7-18 years, attending state schools (452 m and 443 f) and Seventh-day Adventist schools (427 m and 4...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To determine which component of the metabolic syndrome (MetS) is the best predictor of its development. SUBJECTS/METHODS:In this cohort study, 2279 subjects aged 20-87 years without MetS selected from among the participants of the cross-sectional phase of the Tehran Lipid and Glucose Study (TLGS)...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.111
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Globally, fruit and vegetable intakes are well below recommendations despite ample evidence to link insufficient intake with increased risk of overweight and obesity. Intakes of fruits and vegetables in the general population differ between males and females, and although there is growing evidence...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/ejcn.2015.123
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of low and marginal iodine intake and urinary iodine excretion among adults in the Netherlands and to investigate determinants of urinary iodine excretion. DESIGN AND SUBJECTS:The study population consisted of 444 people aged 20-79 y, balanced for sex and 10 y age classes with an ove...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00