Abstract:
BACKGROUND/OBJECTIVES:Considering the importance of glucose as a brain substrate, the postprandial rate of glucose delivery to the blood could be expected to affect cognitive functions. The purpose was to evaluate to what extent the rate of glucose absorption affected measures of cognitive performance in the postprandial period. In addition, cognitive performance was evaluated in relation to individual glucoregulation. SUBJECTS/METHODS:A white wheat bread (WWB) enriched with guar gum (G-WWB) with the capacity to produce a low but sustained blood glucose net increment was developed. The G-WWB was evaluated in the postprandial period after breakfast with respect to effects on cognitive function (working memory and selective attention (SA)) in 40 healthy adults (49-71 years, body mass index 20-29 kg/m(2)), using a high glycaemic index WWB for comparison in a randomised crossover design. RESULTS:The G-WWB improved outcome in the cognitive tests (SA test) in the later postprandial period (75-225 min) in comparison with the WWB (P<0.01). Subjects with better glucoregulation performed superior in cognitive tests compared with subjects with worse glucoregulation (P<0.05). CONCLUSIONS:Beneficial effects on cognitive performance were observed with the G-WWB in the late postprandial period. The positive effect is suggested to emanate from improved insulin sensitivity, possibly in a combination with an enhanced neural energy supply. The results highlight the importance of carbohydrate foods that induces a low but sustained blood glucose profile in enhancing postprandial cognitive functions.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Nilsson A,Radeborg K,Björck Idoi
10.1038/ejcn.2012.80subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1039-43issue
9eissn
0954-3007issn
1476-5640pii
ejcn201280journal_volume
66pub_type
杂志文章,随机对照试验abstract::Adverse reaction to cow's milk and infant formulas are common during infancy. Cow's milk has more than 20 constituents proteins and in principle many are capable of giving rise to an IgE mediated response. The prevalence of cow's milk allergy is between 0.5-10% of the paediatric population (Frier & Kletter, 1970, Gerr...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
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abstract::This article was originally published under Nature Research's License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the article have been modified accordingly. ...
journal_title:European journal of clinical nutrition
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abstract::More than 20 years of serological approach to diagnosis of celiac disease (CD) has deeply changed the classical clinical presentation of the disease, and some reports indicate that CD and obesity can coexist in both childhood and adolescence. We reviewed clinical records of 149 children with CD followed in our institu...
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2009-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1995-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The prolongation of healthy life expectancy (HALE) is a core issue of health policy in many countries. The purpose of this study is to clarify the relationship between dietary diversity and HALE using international databases. MATERIALS/METHODS:HALE data by country were derived from the Global Bur...
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更新日期:2019-03-01 00:00:00
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更新日期:2000-12-01 00:00:00
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journal_title:European journal of clinical nutrition
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更新日期:2006-07-01 00:00:00
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更新日期:2015-02-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
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doi:10.1038/sj.ejcn.1600775
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doi:
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更新日期:2017-09-01 00:00:00
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journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
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