Association of dietary components with dyslipidemia and low-grade inflammation biomarkers in adults with heterozygous familial hypercholesterolemia from different countries.

Abstract:

:The association of components of a low saturated fat (SFA) and of a Mediterranean diet was tested with atherosclerosis biomarkers in 190 familial hypercholesterolemia adults (FH) from Brazil (BR) and Spain (SP). Median blood LDL-C, Apolipoprotein B (apoB), and C reactive protein (hs-CRP) concentrations were higher in BR than in SP: 179.0 vs.161 mg/dL; 141 vs. 103 mg/dL; and 1.6 vs. 0.8 mg/L respectively (all p < 0.001). In BR there was lower median total fat (22.3 vs. 38.3%) and SFA (8.1 vs. 12.5%) but higher cholesterol (283.3 mg vs.188.9 mg) and carbohydrate (57.1 vs. 42.5%) consumption (all p < 0.001). Inverse associations were encountered between fibers, mono, and polyunsaturated fats and their ratios to SFA with LDL-C and ApoB (all p < 0.001). There was a direct association respectively of cholesterol with lipid biomarkers and of carbohydrates and trans-fatty acids with hs-CRP while other fats showed inverse relations with the latter (p < 0.001).

journal_name

Eur J Clin Nutr

authors

Antoniazzi L,Arroyo-Olivares R,Bittencourt MS,Tada MT,Lima I,Jannes CE,Krieger JE,Pereira AC,Quintana-Navarro G,Muñiz-Grijalvo O,Díaz-Díaz JL,Zambón D,Mata P,Santos RD

doi

10.1038/s41430-019-0529-3

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

1622-1625

issue

12

eissn

0954-3007

issn

1476-5640

pii

10.1038/s41430-019-0529-3

journal_volume

73

pub_type

杂志文章
  • Randomised double-blind trial of the effect of vitamin A supplementation of Indonesian pregnant women on morbidity and growth of their infants during the first year of life.

    abstract:OBJECTIVE:To investigate whether supplementation with vitamin A together with iron of Indonesian pregnant women decreases morbidity and improves growth of their infants during the first year of life. DESIGN:Women from a rural area in West Java, Indonesia, were randomly assigned on an individual basis to double-blind s...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1038/sj.ejcn.1601318

    authors: Schmidt MK,Muslimatun S,Schultink W,West CE,Hautvast JG

    更新日期:2002-04-01 00:00:00

  • Dietary intake in asylum seeker children in The Netherlands, strongly related to age and origin.

    abstract:OBJECTIVE:To monitor the dietary intake of energy, macro- and micronutrients in asylum seeker children. DESIGN AND SETTING:Cross-sectional study in three asylum seeker centres in The Netherlands. SUBJECTS:Hundred and sixteen children 2-12 years old (86% of the study cohort) provided a dietary history. METHOD:The die...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602501

    authors: Stellinga-Boelen AA,Wiegersma PA,Bijleveld CM

    更新日期:2007-01-01 00:00:00

  • Design effects associated with dietary nutrient intakes from a clustered design of 1 to 14-year-old children.

    abstract:OBJECTIVE:To calculate intra-cluster and intra-household design effects and intra-class correlation coefficients for dietary nutrients obtained from a 24 h record-assisted recall. DESIGN:Children were recruited using clustered probability sampling. Randomly selected starting-point addresses were obtained with probabil...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602618

    authors: Metcalf PA,Scragg RK,Stewart AW,Scott AJ

    更新日期:2007-09-01 00:00:00

  • Associations between body composition, physical capabilities and pulmonary function in healthy older adults.

    abstract:BACKGROUND/OBJECTIVES:There are positive associations between pulmonary function (PF) and fat-free mass as well as muscle strength. Contrarily, negative associations were found with indirect measures of visceral adipose tissue (VAT). We aimed to differentiate between associations of body composition and PF by assessing...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2016.146

    authors: Schweitzer L,Geisler C,Johannsen M,Glüer CC,Müller MJ

    更新日期:2017-03-01 00:00:00

  • Views of parents in four European countries about the effect of food on the mental performance of primary school children.

    abstract:BACKGROUND/OBJECTIVES:Several factors affect the mental performance of children. The importance that parents attribute to food-related determinants, compared with genetic, socio-economic and school environment, was investigated. SUBJECTS/METHODS:Parents of school children (aged 4-11) were recruited through state prima...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2013.214

    authors: Gage H,Egan B,Williams P,Györei E,Brands B,López-Robles JC,Campoy C,Koletzko B,Decsi T,Raats M

    更新日期:2014-01-01 00:00:00

  • Food intake, energy balance and body weight control.

    abstract::Obesity is a multifactorial and complex affectation that is characterized by a long-term excess energy intake (EI) above energy expenditure (EE). Since fat oxidation seems to be dependent on SNS activation and also seems to remain acutely unaffected by fat intake, this macronutrient is certainly partly responsible for...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,评审

    doi:10.1038/sj.ejcn.1600497

    authors: Doucet E,Tremblay A

    更新日期:1997-12-01 00:00:00

  • Strategies to increase protein intake at mealtimes through a novel high-frequency food service in hospitalized patients.

    abstract:BACKGROUND/OBJECTIVES:Additional strategies should be applied to optimize hospital food services, in order to increase the number of patients with adequate protein intake at mealtimes. Therefore, we aim to specify the differences in protein intake per mealtime between the traditional three meals a day food service (TMS...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/s41430-018-0288-6

    authors: Dijxhoorn DN,IJmker-Hemink VE,Wanten GJA,van den Berg MGA

    更新日期:2019-06-01 00:00:00

  • Comparative measurement of ghrelin, leptin, adiponectin, EGF and IGF-1 in breast milk of mothers with overweight/obese and normal-weight infants.

    abstract:BACKGROUND/OBJECTIVES:Obese infants are more susceptible to develop adulthood obesity and its related comorbidities. Previous studies have shown the presence of hormones and growth factors in maternal breast milk that may influence infant adiposity. The aim of this study was to investigate differences in concentrations...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2014.205

    authors: Khodabakhshi A,Ghayour-Mobarhan M,Rooki H,Vakili R,Hashemy SI,Mirhafez SR,Shakeri MT,Kashanifar R,Pourbafarani R,Mirzaei H,Dahri M,Mazidi M,Ferns G,Safarian M

    更新日期:2015-05-01 00:00:00

  • Dietary patterns and risk of nonfatal acute myocardial infarction in Costa Rican adults.

    abstract:OBJECTIVE:To investigate the association between dietary patterns and risk of a first nonfatal acute myocardial infarction (MI) in Costa Rican adults. DESIGN:Population-based case-control study. SUBJECTS:A total of 496 incident MI cases and 518 population-based randomly selected controls matched to the cases by age (...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602381

    authors: Martínez-Ortiz JA,Fung TT,Baylin A,Hu FB,Campos H

    更新日期:2006-06-01 00:00:00

  • Dietary modulators of blood pressure in hypertension.

    abstract::To study the role of diet, 197 patients of essential hypertension were randomized to either experimental diet (group A, 97 cases) or normal diet (group B, 100 cases) with diuretics given to both the groups. The age varied between 25 and 65 years and 154 were males. The study diet included a significantly higher conten...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Singh RB,Sircar AR,Rastogi SS,Singh R

    更新日期:1990-04-01 00:00:00

  • Fascial planes within subcutaneous fat in humans.

    abstract::We have used B-mode (brightness-mode) ultrasound to investigate the fascial planes within subcutaneous fat at the triceps and abdominal sites in a group of 17 women attending a weight control group over a 12 month period. In most subjects there was a single intralipid fascial plane at each site. As the thickness of ad...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Alexander HG,Dugdale AE

    更新日期:1992-12-01 00:00:00

  • Relationship between plasma selenium concentrations and lower genital tract levels of HIV-1 RNA and interleukin type 1beta.

    abstract:OBJECTIVE:To examine the relationship between selenium nutritional status and intermediates of human immunodeficiency virus (HIV)-1 transmission. DESIGN:Prospective cohort study. SETTING:A study clinic at Muhimbili National Hospital, Dar es Salaam, Tanzania. SUBJECTS:A total of 340 HIV-1-infected pregnant women with...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602567

    authors: Kupka R,Msamanga GI,Xu C,Anderson D,Hunter D,Fawzi WW

    更新日期:2007-04-01 00:00:00

  • Selenium intakes in 18-64-y-old Irish adults.

    abstract:OBJECTIVE:To measure the intake of selenium (Se) and the contribution of different food groups to Se intake in adults aged 18-64 y in Ireland. The adequacy of Se intake in the population is also assessed. DESIGN:Food consumption was estimated using a 7 day food diary for a representative sample (n=1379; men=662, women...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601323

    authors: Murphy J,Hannon EM,Kiely M,Flynn A,Cashman KD

    更新日期:2002-05-01 00:00:00

  • Swedish obese subjects (SOS): an obesity intervention study with a nutritional perspective.

    abstract:OBJECTIVES:Swedish Obese Subjects (SOS) is a multidisciplinary project involving aspects of obesity ranging from description of the severely obese state to effects of surgical intervention on long-term mortality and morbidity. Dietary studies, which represent an integral part of SOS research activities, are the focus o...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,评审

    doi:10.1038/sj.ejcn.1600567

    authors: Lissner L,Lindroos AK,Sjöström L

    更新日期:1998-05-01 00:00:00

  • Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmö Diet and Cancer cohort.

    abstract:OBJECTIVES:The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies. SUBJECTS AND METHODS:Twenty-six women born between 1940 and 1950 were recruited ...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1602811

    authors: Sonestedt E,Ericson U,Gullberg B,Peñalvo JL,Adlercreutz H,Wirfält E

    更新日期:2008-08-01 00:00:00

  • Major dietary patterns of young and middle aged women: results from a prospective Australian cohort study.

    abstract:OBJECTIVE:The aim of this study was to assess the major dietary patterns of two age cohorts of women, to determine to the extent to which the dietary patterns differ between the cohorts and to assess whether they vary according to sociodemographic and behavioural characteristics and patterns of nutrient intake. METHOD...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2010.121

    authors: Mishra GD,McNaughton SA,Ball K,Brown WJ,Giles GG,Dobson AJ

    更新日期:2010-10-01 00:00:00

  • Long-term changes in gut hormones, appetite and food intake 1 year after subtotal gastrectomy with normal body weight.

    abstract:BACKGROUND/OBJECTIVES:No prospective study on the long-term effects of gastric resection on gastrointestinal hormonal changes in patients with normal body weight has been reported. The aim of this study was to evaluate the 1-year effect of subtotal gastrectomy on ghrelin and peptide YY (PYY)(3-36) levels. SUBJECTS/MET...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/ejcn.2010.83

    authors: Jeon TY,Lee S,Kim HH,Kim YJ,Lee JG,Jeong DW,Kim YJ

    更新日期:2010-08-01 00:00:00

  • Effects of an oat bran concentrate on serum lipids in free-living men with mild to moderate hypercholesterolaemia.

    abstract::An oat bran concentrate was prepared by removing non-fibre components by cold-water wet-milling, resulting in a 2- to 3-fold concentration of soluble fibre, with beta-D-glucan as its main component. The concentrate was baked in bread which was consumed for 8 weeks by free-living men with mild to moderate hypercholeste...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Törrönen R,Kansanen L,Uusitupa M,Hänninen O,Myllymäki O,Härkönen H,Mälkki Y

    更新日期:1992-09-01 00:00:00

  • n-3 fatty acids in human fat tissue aspirates are stable for up to 6 y.

    abstract:OBJECTIVES:The content of n-3 (omega-3) polyunsaturated fatty acids in fat tissue is a valid indicator of their long-term consumption. We studied the stability of n-3 fatty acids in human subcutaneous fat microbiopsies after 6 and 11 y of storage. DESIGN:Microbiopsies were taken from a lump of human adipose tissue and...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601614

    authors: Katan MB,Harryvan JL,van de Bovenkamp P

    更新日期:2003-07-01 00:00:00

  • Effect of winter oral vitamin D3 supplementation on cardiovascular risk factors in elderly adults.

    abstract:OBJECTIVE:A possible role for vitamin D deficiency in contributing to the winter increase in cardiovascular disease mortality was investigated by testing the effect of vitamin D supplementation on blood pressure and other cardiovascular risk factors during winter. DESIGN:Randomised double-blind trial of vitamin D supp...

    journal_title:European journal of clinical nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Scragg R,Khaw KT,Murphy S

    更新日期:1995-09-01 00:00:00

  • The economic case for prevention of population vitamin D deficiency: a modelling study using data from England and Wales.

    abstract:BACKGROUND:Vitamin D deficiency (VDD) affects the health and wellbeing of millions worldwide. In high latitude countries such as the United Kingdom (UK), severe complications disproportionally affect ethnic minority groups. OBJECTIVE:To develop a decision-analytic model to estimate the cost effectiveness of population...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/s41430-019-0486-x

    authors: Aguiar M,Andronis L,Pallan M,Högler W,Frew E

    更新日期:2020-05-01 00:00:00

  • On the importance of processing conditions, product thickness and egg addition for the glycaemic and hormonal responses to pasta: a comparison with bread made from 'pasta ingredients'.

    abstract::The importance of processing conditions, product thickness and effect of egg addition for the glycaemic and hormonal responses to pasta was studied. Healthy subjects were given test meals with an equivalent amount of available carbohydrate from extruded high-temperature dried spaghetti and three varieties of fresh rol...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: Granfeldt Y,Björck I,Hagander B

    更新日期:1991-10-01 00:00:00

  • Dual-energy X-ray absorptiometry for body composition estimation in Chinese women.

    abstract:OBJECTIVE:To determine whether dual-energy X-ray absorptiometry (DXA) is a valid method for body composition assessment of obese and non-obese subjects. DESIGN:Cross-sectional study. SUBJECTS:Chinese women living in Hong Kong; 66 of 91 subjects had body mass index (BMI) of >25 kg/m2. MEASUREMENTS:Anthropometrics, in...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1600875

    authors: He M,Li ET,Kung AW

    更新日期:1999-12-01 00:00:00

  • Changes in the intake of vitamins and minerals by men and women with hyperlipidemia and overweight during dietetic treatment.

    abstract:OBJECTIVES:To assess the influence of a low-fat, low-energy diet on the intake of vitamins and minerals in patients with overweight and hyperlipidemia. SETTING:Outpatient clinic for hyperlipidemia treatment. SUBJECTS:A total of 134 subjects chosen from patients attending Outpatient Clinic of Metabolic Diseases. INTE...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601467

    authors: Grzybek A,Klosiewicz-Latoszek L,Targosz U

    更新日期:2002-12-01 00:00:00

  • The relationship between organ-tissue body composition and resting energy expenditure in prepubertal children.

    abstract:BACKGROUND/OBJECTIVES:In this study, we ascertained the relationship between resting energy expenditure (REE) obtained using two procedures: indirect calorimetry and from organ-tissue mass, calculated employing magnetic resonance imaging (MRI), and adult metabolic rate constants, in prepubertal children. Differences be...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/s41430-018-0344-2

    authors: Midorikawa T,Hikihara Y,Ohta M,Ando T,Torii S,Sakamoto S,Tanaka S

    更新日期:2019-08-01 00:00:00

  • Energy metabolism and requirements in different ethnic groups.

    abstract::Some studies on energy metabolism of men and women in Third World countries suggested that their basal metabolic rate (BMR) is lower compared to BMRs of people in Northern European and American countries. It is, however, not clear whether this results from ethnic factors, climate or adaptation to, for instance, a low ...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:

    authors: de Boer JO,van Es AJ,Voorrips LE,Blokstra F,Vogt JE

    更新日期:1988-12-01 00:00:00

  • Energy stress during pregnancy and lactation: consequences for maternal nutrition in rural Bangladesh.

    abstract:OBJECTIVE:To assess the relationship of energy stress during pregnancy and lactation to maternal body stores in marginally nourished rural Bangladeshi women. SUBJECTS AND METHODS:Two-hundred and fifty-two women were followed from 5-7 months of pregnancy until 6 months postpartum. Energy intake was estimated during pre...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601514

    authors: Alam DS,Van Raaij JM,Hautvast JG,Yunus M,Fuchs GJ

    更新日期:2003-01-01 00:00:00

  • Response rates with different distribution methods and reward, and reproducibility of a quantitative food frequency questionnaire.

    abstract:OBJECTIVES:To evaluate the use of a self-administered quantitative food frequency questionnaire (QFFQ) in a national dietary survey concerning (a) response rates with different distribution methods and reward; (b) degree of underreporting of energy intake; (c) reproducibility of the QFFQ; and (d) seasonal variation on ...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1600410

    authors: Johansson L,Solvoll K,Opdahl S,Bjørneboe GE,Drevon CA

    更新日期:1997-06-01 00:00:00

  • Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study.

    abstract:BACKGROUND/OBJECTIVES:Prospective cohort studies have indicated that serum vitamin D levels are inversely related to risk of type 2 diabetes. However, such studies cannot determine the source of vitamin D. Therefore, we examined the association of dietary vitamin D intake with incident type 2 diabetes within the Europe...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章,多中心研究

    doi:10.1038/ejcn.2013.235

    authors: Abbas S,Linseisen J,Rohrmann S,Beulens JW,Buijsse B,Amiano P,Ardanaz E,Balkau B,Boeing H,Clavel-Chapelon F,Fagherazzi G,Franks PW,Gavrila D,Grioni S,Kaaks R,Key TJ,Khaw KT,Kühn T,Mattiello A,Molina-Montes E,Nilsso

    更新日期:2014-02-01 00:00:00

  • Dose-response relationship between fat ingestion and oxidation: quantitative estimation using whole-body calorimetry and 13C isotope ratio mass spectrometry.

    abstract:OBJECTIVE:To determine dose-dependent relationship between ingested fat and its oxidation in the immediate post-prandial period in humans. DESIGN:Subjects were randomly selected for the study at the Dunn Clinical Nutrition Centre, Cambridge, UK. Subjects ingested naturally enriched 13C corn-oil doses (range 20-140g) i...

    journal_title:European journal of clinical nutrition

    pub_type: 杂志文章

    doi:10.1038/sj.ejcn.1601112

    authors: Sonko BJ,Prentice AM,Coward WA,Murgatroyd PR,Goldberg GR

    更新日期:2001-01-01 00:00:00