Abstract:
BACKGROUND/OBJECTIVES:There are positive associations between pulmonary function (PF) and fat-free mass as well as muscle strength. Contrarily, negative associations were found with indirect measures of visceral adipose tissue (VAT). We aimed to differentiate between associations of body composition and PF by assessing mediating and moderating effects of physical capabilities. SUBJECTS/METHODS:Cross-sectional data were assessed among 40 healthy, free-living elderly (20 males) aged 65.1-81.2 years (mean±s.d. age: 72.2±4.3 years; body mass index: 25.6±3.7 kg/m2). Total and regional skeletal muscle (SM), and adipose tissue (AT) were measured using whole-body magnetic resonance imaging. Muscle strength by handgrip dynamometry, physical activity (PA) by questionnaire, and physical performance by gait speed and sit-to-stand test (STS). Forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) were assessed by spirometry. RESULTS:Positive associations between height-standardized FVC (FVCI) as well as FEV1 (FEVI), and SM (r=0.435-0.520, P<0.05) were found; subcutaneous AT (SAT) and FVCI correlated negatively (r=-0.374; P<0.05). HGS and PA correlated positively with FEVI (r=0.456-0.608, P<0.05), HGS also with FVCI (r=0.595, P<0.05). Stepwise multiple regression using FVCI and FEVI as dependent variables, and total/thoracic SM, VAT, SAT, HGS, PA and physical performance as independent variables showed that (i) only HGS entered the regression for predicting FVCI (R2=0.351; standard error of estimation (SEE)=0.32 l), and (ii) HGS and PA explained 50% of FEVI (SEE=0.23 l). HGS mediated the relationship between SM and PF; the STS moderated the relationship between SM and FVCI. CONCLUSIONS:In healthy elderly, PF is positively associated with SM; physical capabilities mediate and moderate these relationships.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Schweitzer L,Geisler C,Johannsen M,Glüer CC,Müller MJdoi
10.1038/ejcn.2016.146subject
Has Abstractpub_date
2017-03-01 00:00:00pages
389-394issue
3eissn
0954-3007issn
1476-5640pii
ejcn2016146journal_volume
71pub_type
杂志文章abstract::Water, an essential nutrient, is often ignored in reports of dietary surveys and nutrition. Although it is ubiquitous in foods and beverages, the attention is often focused on the minerals or calorific values of the fluids imbibed rather than the water per se. Water is often taken for granted by many in Western countr...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2013.11
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To investigate the relation between lactation and markers of folate and vitamin B12 (B12) deficiency in women with and without vitamin supplementation. DESIGN:A 9-month follow-up study. SUBJECTS AND METHODS:Blood samples from 91 women, who gave birth to a single healthy child, were collected 3 weeks, 4 and ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602275
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:We analysed at what age parents start complementary food in very low birth weight infants, determined risk factors for early introduction of complementary food (post-term age) and analysed whether the age at introduction of complementary food influences height or weight at 2 years of age. SUBJECT...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.54
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVE:To define the cellular basis for immune enhancement by a probiotic lactic acid bacteria strain (Bifidobacterium lactis HN019); and to determine whether immune enhancement can be optimized by delivery in oligosaccharide-enriched low-fat milk. DESIGN:A double-blind, three-stage before-and-after intervention tr...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601093
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effects of long-term excessive iodine intake on blood lipids in adults. METHODS:Three counties from Dezhou city and Liaocheng city in the Shandong province of China were selected as survey locations. Three to five villages were selected from each county and then cate...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-00773-6
更新日期:2020-10-11 00:00:00
abstract:BACKGROUND/OBJECTIVES:A major goal of the European Food Information Resource (EuroFIR) Network of Excellence is to provide tools to overcome existing differences among member states and parties with respect to documentation and interchange of food composition data. Establishment of a common CEN (Comité Européen de Norm...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2010.210
更新日期:2010-11-01 00:00:00
abstract::Nutrition education for medical students in the University of Otago, New Zealand, has been adapted to comply with the newly introduced system-based teaching. Clinical cases provide the focus for class demonstrations, tutorials, self-directed learning and a limited number of lectures. In the preclinical curriculum nutr...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600805
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:In view of the ongoing debate on "chronic malnutrition" and the concept of "stunting" as "a better measure than underweight of the cumulative effects of undernutrition and infection (WHO)", we translate, briefly comment and re-publish three seminal historic papers on catch-up growth following re-feeding afte...
journal_title:European journal of clinical nutrition
pub_type: 历史文章,杂志文章,评审
doi:10.1038/s41430-018-0274-z
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Cross-sectionally, educational attainment is strongly associated with the prevalence of obesity, but this association is less clear for weight change during adult life. The objective of this study is to examine the association between educational attainment and weight change during adult life in t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.55
更新日期:2012-08-01 00:00:00
abstract:UNLABELLED:BACKGROUND/ OBJECTIVES: We evaluated plant sterol and stanol (PS) intakes from natural sources and enriched foods in the Finnish population-based national FINDIET 2007 Survey. In addition, we compared the users and nonusers of PS-enriched foods in terms of their characteristics and dietary intake. SUBJECTS/...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.3
更新日期:2014-05-01 00:00:00
abstract::The importance of processing conditions, product thickness and effect of egg addition for the glycaemic and hormonal responses to pasta was studied. Healthy subjects were given test meals with an equivalent amount of available carbohydrate from extruded high-temperature dried spaghetti and three varieties of fresh rol...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:Both epidemiological and experimental evidence suggests a protective effect of dietary fiber against disease, such as cancer and cardiovascular disease. The effects of fiber on lipoproteins are modest, indicating that other mechanisms may be involved. As the hemostatic effects of different types of fiber are ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600975
更新日期:2000-05-01 00:00:00
abstract::The objective of this study was to measure lutein and zeaxanthin plasma levels after oral lutein administration in preterm infants. Lutein was given orally in a single dose of 0.5 mg/kg to 10 preterm infants at a mean age of 52 h of life. Plasma lutein and zeaxanthin were measured before and 6, 24, 48, and 120 h after...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章
doi:10.1038/ejcn.2010.62
更新日期:2010-07-01 00:00:00
abstract::Nutrition affects the brain throughout life, with profound implications for cognitive decline and dementia. These effects are mediated by changes in expression of multiple genes, and responses to nutrition are in turn affected by individual genetic variability. An important layer of regulation is provided by the epige...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/ejcn.2014.173
更新日期:2014-11-01 00:00:00
abstract::The aim of this survey was to examine differences in personality profiles among 198 vegan (n = 64; 32.3%), vegetarian (n = 78; 39.4%) and omnivore (n = 55; 27.8%) medical professionals. Outcomes were motives for the nutritional approaches, WHO QoL-BREF, Big Five SOEP Inventory, Portraits Value Questionnaire, and Empat...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-017-0007-8
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To describe drinking patterns among individuals who prefer drinking wine, beer or spirits. DESIGN:Cross-sectional study obtaining detailed information on intake of wine, beer and spirits and on frequency of alcohol intake. Adjustment for gender, age, smoking habits, educational attainment and body mass index...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600919
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To examine the effects of alpha (s1)-casein hydrolysate on females with stress-related symptoms. DESIGN:Double-blind, randomized, crossover, placebo-controlled trial. SETTING:The alpha (s1)-casein hydrolysate was manufactured by INGREDIA (Arras, France) and the placebo was manufactured by DIETAROMA (Bourg, ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602553
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between weight gain, changes in body composition and physiological characteristics of fitness during the recovery from anorexia nervosa. DESIGN:Longitudinal over eight weeks of intensive inpatient re-feeding (Wk 0-8). SETTING:The London Hospital Medical College. SUBJECTS:Ten fem...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:We hypothesized that very low birth weight (VLBW) infants have reduced serum and red blood cell (RBC) selenium (Se) at birth, which decrease further with current nutrition and are associated with chronic lung disease and septicaemia. DESIGN:We studied Se intake, concentration in serum and RBCs and glutathion...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602715
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In international surveys of food consumption and nutrient intake, it is essential that the dietary data are comparable when different databases and calculation programs are used. The aim of the present analysis was to examine the comparability of nutrient intake data calculated on the basis of ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601639
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:To estimate the energy cost of resting (RMR), sitting and standing for urban Indian adults and compare these estimates with the reported values. DESIGN:Energy costs were measured using oxylog while body fat was estimated using equipment (HBF300, OMRON Corporation, Japan) that works on the principle of bioel...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601211
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVE:This study describes the prevalence and characteristics of an elevated resting energy expenditure (REE) in patients with chronic obstructive pulmonary disease (COPD). DESIGN AND SETTING:Patients were consecutively admitted to an in-patient pulmonary rehabilitation centre. SUBJECTS:The study group consisted ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600571
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Human milk vitamin B12 (B12) concentrations depend on maternal status and intake; only few data are available in high-income countries. OBJECTIVE:We assessed human milk B12 concentrations during the first 6 months postpartum in Norwegian women and its association with maternal dietary B12 intake and materna...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0567-x
更新日期:2020-05-01 00:00:00
abstract::In this issue we would like to thank all those listed below for taking the time to review for the European Journal of Clinical Nutrition in 2019-your generosity is much appreciated and we hope your association with the journal continues in the future. ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-020-0589-4
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To provide a reference range for plasma total homocysteine (tHcy), an independent risk factor for vascular disease, and to explore relationships with nutritional indices for people aged 65 y and over, in the UK National Diet and Nutrition Survey (NDNS). DESIGN:The survey procedures described in the National...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600468
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The cardiovascular benefit of increasing fruit and vegetable (F&V) intake following diagnosis of diabetes remains unknown. We aimed to describe how quantity and variety of F&V intake, and plasma vitamin C, change after diagnosis of type 2 diabetes and examine whether these changes are associated w...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.180
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate two interventions (one reward-based and one exposure-based) for increasing children's acceptance of an unfamiliar vegetable compared with a no-treatment control. It was predicted that the exposure condition would increase liking for, and consumption of, the vegetable rela...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601541
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Iron and phosphate are both vital to many biological cellular processes with central roles in energy metabolism, cellular proliferation and nucleic acid synthesis. Regulatory pathways in some of these metabolic pathways may intersect at fibroblast growth factor 23 (FGF23), a major phosphate regula...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.217
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To study risk factors for and prevalence and validity of clinical-anthropometrical mismatch (CAM) defined as the presence of clinical signs of protein-energy malnutrition despite normal weight-for-age (WFA). DESIGN:A semi-longitudinal study of nutrition and morbidity with a longitudinal assessment of mortali...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:Dietary counseling and intervention based on application of conventional criteria have been ineffective in preventing the progressive weight loss associated with HIV infection. The aim of the study was to compare the progression of clinical and nutritional indicators during nutritional supplementation with or...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601276
更新日期:2001-12-01 00:00:00