Abstract:
OBJECTIVE:To investigate whether the protection observed for some micronutrients, such as beta-carotene, in several observational studies may simply reflect vegetable and fruit intake. DESIGN:A case-control study conducted in Italy. SUBJECTS:The subjects were 1225 colon cancer patients, 728 rectal cancer patients and 4154 hospital controls. RESULTS:For the 16 micronutrients considered, the more closely a micronutrient was correlated with total vegetable and fruit intake, the more it appeared protective against colorectal cancer. CONCLUSION:When studying the effect of a nutrient on disease risk in an observational setting, its relation to other nutrients and foods must be taken into account.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Negri E,La Vecchia C,Franceschi Sdoi
10.1038/sj.ejcn.1601317subject
Has Abstractpub_date
2002-02-01 00:00:00pages
166-70issue
2eissn
0954-3007issn
1476-5640journal_volume
56pub_type
杂志文章abstract:OBJECTIVE:To study the relation between indicators of infection and Schistosoma mansoni and S. haematobium infection, and serum concentrations of zinc, ferritin and retinol. DESIGN:Cross-sectional. SETTING AND SUBJECTS:313 rural Zimbabwean schoolchildren (144 boys and 169 girls, 11-17 years). VARIABLES:S. mansoni an...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:To assess four-year changes in different measures of health, functional limitations and activities of daily living occurring in elderly Europeans who participated in the SENECA surveys of 1988/89 and 1993. METHODS:Similar questions on self-perceived health, chronic diseases, drug intake and activities of dai...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of dosage on the metabolic response to vegetables added to a mixed lunch meal, and to relate the amounts to the tripartite plate model. Carrots were chosen as an example, and the carrots were blanched, frozen and boiled to include possible effects of processing and cooking. The effects ...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-06-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between weight gain, changes in body composition and physiological characteristics of fitness during the recovery from anorexia nervosa. DESIGN:Longitudinal over eight weeks of intensive inpatient re-feeding (Wk 0-8). SETTING:The London Hospital Medical College. SUBJECTS:Ten fem...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Neuropeptide Y (NpY) is an important factor in neuropeptide signalling, and significantly change in the blood and cerebrospinal fluid (CSF) during chronic kidney disease (CKD) progression. However, the role of NpY remains unclear. We aimed to investigate the associations between NpY levels, nutrit...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2015.67
更新日期:2015-06-01 00:00:00
abstract:OBJECTIVES:To provide a reference range for plasma total homocysteine (tHcy), an independent risk factor for vascular disease, and to explore relationships with nutritional indices for people aged 65 y and over, in the UK National Diet and Nutrition Survey (NDNS). DESIGN:The survey procedures described in the National...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600468
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Iron and phosphate are both vital to many biological cellular processes with central roles in energy metabolism, cellular proliferation and nucleic acid synthesis. Regulatory pathways in some of these metabolic pathways may intersect at fibroblast growth factor 23 (FGF23), a major phosphate regula...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.217
更新日期:2017-02-01 00:00:00
abstract::Dietary energy restriction is the only proven method for extending lifespan and slowing aging in mammals, while maintaining health and vitality. Although the first experiments in this area were conducted over 60 y ago in rodents, possible applicability to primates has only been examined in controlled studies since 198...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1601020
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVES:This paper reports the effects of an energy and micronutrient supplement on skeletal maturation of nutritionally at risk infants and toddlers in Pangalengan, Indonesia. DESIGN:Two cohorts of children were randomly assigned to three treatments: E = 1171 kJoule + 12 mg iron; M = 12 mg iron + 209 kJ; S = 104 k...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601008
更新日期:2000-05-01 00:00:00
abstract::Consumers and patients are unsure of whom to trust for nutritional advice. Although medical doctors are seen as experts in nutrition and their advice is regularly followed, data are lacking on the amount of nutrition education in European medical school curricula. In line with US research, we distributed a survey on r...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.75
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To study risk factors for and prevalence and validity of clinical-anthropometrical mismatch (CAM) defined as the presence of clinical signs of protein-energy malnutrition despite normal weight-for-age (WFA). DESIGN:A semi-longitudinal study of nutrition and morbidity with a longitudinal assessment of mortali...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:The relationship between hydrogen and methane production is a possible confounding factor in the interpretation of H(2) breath tests (HBT), but is usually disregarded for the interpretation of HBT and, in most instances, only H(2) excretion is measured. The present study was designed to evaluate the effect o...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1601651
更新日期:2003-09-01 00:00:00
abstract::We examined the relationships between insulin sensitivity (IS), skeletal muscle (SM) mass and SM quality in youth. Forty obese adolescent boys (body mass index ≥ 95 th percentile, 12-18 years) participated in this study. IS and glucose tolerance was measured by a 3 h hyperinsulinemic-euglycemic clamp and a 2 h oral gl...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.142
更新日期:2012-12-01 00:00:00
abstract::Nutrient profiling classifies individual food products according to their nutrient content. According to the WHO (World Health Organization), validation is a key step in the development of a nutrient profiling system. The aim was to assess the construct validity of five European nutrient profiling systems (Choices, Ke...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2013.95
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To collect (i) baseline data and (ii) execute a large multicentre study examining the effect of trans alpha-linolenic acid on its incorporation into plasma lipids and on risk factors for coronary heart disease. DESIGN:Male volunteers were recruited and the habitual diet assessed by a 4-d weighed record. Fatt...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1600903
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:In most populations the prevalence of obesity is greater in women than in men; however, the magnitude of the difference between the sexes varies significantly by country. We considered the role of gender inequality in explaining these disparities. SUBJECTS/METHODS:We undertook an ecological analy...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2014.86
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Investigating the effect on post-prandial glycemic and venous serum insulin response of an apple drink following the conversion of its glucose to gluconate. SUBJECTS/METHODS:In a double-blind randomized placebo-controlled clinical trial with cross-over design, 30 male adults with impaired fasting...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41430-019-0421-1
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To determine current practice in the delivery of parenteral nutrition (PN) in Australian hospitals. DESIGN:A cross-sectional mail survey. SETTING:Acute-care adult hospitals with greater than 200 beds in Australia. SUBJECTS:A total of 67 hospitals (65.7% response rate). INTERVENTION:Surveys were posted to ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602547
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:It was determined whether a combination of Lactobacillus acidophilus (L. acidophilus) 74-2 and Bifidobacterium animalis subsp lactis DGCC 420 (B. lactis 420) affect the faecal microbiota as well as immunological parameters and blood lipids in healthy adults. DESIGN:A placebo-controlled, double-blinded, rando...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602761
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Heavy alcohol drinking is a risk factor of colorectal cancer (CRC), but little is known on the effect of polymorphisms in the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) on the alcohol-related risk of CRC in Caucasian populations. SUBJECTS/METHODS:A...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2012.173
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To assess the effects of smoking on serum lipoprotein levels taking into account current nutritional intakes. DESIGN:Case-control study comparing smokers and non-smokers. SETTING:Ambulatory subjects of the Urban Community of Lille examined at home or at the Health Care Center. SUBJECTS:Men, between 45 and ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVES:A significant proportion of the older population may exhibit vitamin D insufficiency. We sought to establish the proportion of 25-hydroxyvitamin D (25OHD) insufficient individuals in an older female cohort presenting for acute medical admission and how they responded to supplementation. DESIGN:A prospective...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602412
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:There is experimental evidence that riboflavin (vitamin B2) supplementation reduces oxidative damage and cerebral oedema following acute stroke. OBJECTIVE:To measure riboflavin levels in acute stroke before and after supplementation with this vitamin. DESIGN:Ninety-six acute ischaemic stroke patients had t...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1602666
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:Prevention of cardiovascular diseases by paleolithic or hunter-gatherer diets has been discussed during recent years. METHODS:Our aim was to assess the effect of a paleolithic diet in a pilot study on healthy volunteers during 3 weeks. The intention was to include 20 subjects, of whom 14 fulfilled the study...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602790
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To examine the effect of low-dose fish oil supplementation on specific growth factors, purported to play a central role in lesion formation, and also on the total growth factor activity of serum, as assessed by the induction of DNA synthesis in cultured human arterial smooth muscle cells. DESIGN:Randomized p...
journal_title:European journal of clinical nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1038/sj.ejcn.1601076
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To assess the suitability of the body mass index (BMI) as an indicator of standard of living in developing countries. DESIGN, SETTING AND SUBJECTS:The analysis is based on data collected in the first two rounds of the Ghana Living Standards Survey, held in 1987/88 (GLSS-I) and 1988/89 (GLSS-II). The dataset ...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1600528
更新日期:1998-02-01 00:00:00
abstract::Obesity is a multifactorial and complex affectation that is characterized by a long-term excess energy intake (EI) above energy expenditure (EE). Since fat oxidation seems to be dependent on SNS activation and also seems to remain acutely unaffected by fat intake, this macronutrient is certainly partly responsible for...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章,评审
doi:10.1038/sj.ejcn.1600497
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To know the prevalence of malnutrition and to validate a nutritional screening protocol (SP) in patients hospitalised in Hospitals representative of inpatients admitted for acute illnesses in Galicia. DESIGN:Cross-sectional study of 376 randomised patients (189 female, 210 > or =65 y old) from 12 public hosp...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/sj.ejcn.1602157
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:This study investigates the predictors of serum cobalamin concentrations in community-dwelling older adults and the relationship between serum cobalamin and plasma homocysteine. SUBJECTS/METHODS:Serum cobalamin and plasma homocysteine were measured by SimulTRAC-SNB radio assay and HPLC, respectiv...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/s41430-018-0367-8
更新日期:2019-09-01 00:00:00
abstract::Comparison of percent fat mass across different body composition analysis devices is important given variation in technology accuracy and precision, as well as the growing need for cross-validation of devices often applied across longitudinal studies. We compared EchoMRI-AH and Lunar iDXA quantification of percent bod...
journal_title:European journal of clinical nutrition
pub_type: 杂志文章
doi:10.1038/ejcn.2016.236
更新日期:2017-04-01 00:00:00