Abstract:
OBJECTIVES:This paper reports the effects of an energy and micronutrient supplement on skeletal maturation of nutritionally at risk infants and toddlers in Pangalengan, Indonesia. DESIGN:Two cohorts of children were randomly assigned to three treatments: E = 1171 kJoule + 12 mg iron; M = 12 mg iron + 209 kJ; S = 104 kJ. Supplementation was given for 12 months. SETTING:The sites were six tea plantations in Pangalengan, West Java. SUBJECTS:A 12-month-old (n = 53) and an 18-month-old (n = 83) cohort were recruited from day-care-centers. Twenty children that received S belonged to the 12- and 18-month-old cohorts. Inclusion criteria were: no chronic disease; length-for-age < or = -1 standard deviation (s.d.) and weight-for-length between -1 and -2 s.d. of the median of the reference of the World Health Organization. METHODS:Skeletal maturation was measured by X-ray of the left hand and wrist. The number of ossified centers and two different measures of skeletal age (Skel-1 and Skel-2) were the outcome variables measured. RESULTS:In the 12-month-old cohort, there were intergroup differences 6 and 12 months after baseline. First, the children in the E group were about 2 months more advanced in ossified centers than the children in the S group (P < 0.10). At 12 months, the children in the E group were about 3 months more advanced in skeletal age than the children in the M group. M group children were about 2.5 months behind the children in the S group.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Jahari AB,Haas J,Husaini MA,Pollitt Edoi
10.1038/sj.ejcn.1601008subject
Has Abstractpub_date
2000-05-01 00:00:00pages
S74-9eissn
0954-3007issn
1476-5640journal_volume
54 Suppl 2pub_type
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