Translational and transcriptional inhibitors block serotonergic phase advances of the suprachiasmatic nucleus circadian pacemaker in vitro.

abstract：:The circadian timing system has three principal elements: the retina, the intergeniculate leaflet (IGL) of the thalamus, and the suprachiasmatic nucleus (SCN). Since the human circadian timing system cannot be studied experimentally, we have used another primate, the macaque monkey, to help provide insight into the or...

journal_title：Journal of biological rhythms

authors： Moore RY

更新日期：1993-01-01 00:00:00

abstract：:Drosophila littoralis is a latitudinally widespread European species of the Drosophila virilis group. The species has ample genetic variation in photoperiodism (adult diapause) and circadian rhythmicity (pupal eclosion rhythm), with adaptive latitudinal clines in both of them. The possible common genetic basis between...

journal_title：Journal of biological rhythms

authors： Lankinen P,Forsman P

更新日期：2006-02-01 00:00:00

abstract：:Reduced sensitivity to short-wavelength (blue) light with age has been shown for light-induced melatonin suppression. The current research aimed to determine if a similar age-related reduction occurs in subjective alertness, mood, and circadian phase-advancing responses. Young (n = 11, 23.0 +/- 2.9 years) and older (n...

journal_title：Journal of biological rhythms

authors： Sletten TL,Revell VL,Middleton B,Lederle KA,Skene DJ

更新日期：2009-02-01 00:00:00

abstract：:The mammalian circadian clock in the suprachiasmatic nucleus (SCN) drives and maintains 24-h physiological rhythms, the phases of which are set by the local environmental light-dark cycle. Gastrin-releasing peptide (GRP) communicates photic phase setting signals in the SCN by increasing neurophysiological activity of ...

journal_title：Journal of biological rhythms

authors： Gamble KL,Kudo T,Colwell CS,McMahon DG

更新日期：2011-04-01 00:00:00

abstract：:Entrainability of the circadian rhythm of mosquito flight and locomotor activity was investigated by giving a 24-hr temperature cycle (28 degrees C for 16 hr, 23 degrees C for 8 hr) to the free-running rhythm or by shifting the temperature cycle. The phase angle difference between the entrained rhythm and the temperat...

journal_title：Journal of biological rhythms

authors： Chiba Y,Uki M,Kawasaki Y,Matsumoto A,Tomioka K

更新日期：1993-10-01 00:00:00

abstract：:The aim of this study was to replicate and extend previous work in which the authors observed lower, shorter, and advanced nocturnal melatonin secretion patterns in premenstrually depressed patients compared to those in healthy control women. The authors also sought to test the hypothesis that the therapeutic effect o...

journal_title：Journal of biological rhythms

authors： Parry BL,Berga SL,Mostofi N,Klauber MR,Resnick A

更新日期：1997-02-01 00:00:00

abstract：:A gradual adaptation to a shifted light-dark (LD) cycle is a key element of the circadian clock system and believed to be controlled by the central circadian pacemaker, the suprachiasmatic nucleus (SCN). Endocrine factors have a strong influence on the regulation of the circadian clock network and alter acute photic r...

journal_title：Journal of biological rhythms

authors： Pilorz V,Kolms B,Oster H

更新日期：2020-12-01 00:00:00

abstract：:Little is known about the differences in the neural substrates of circadian rhythms that are responsible for the maintenance of differences between diurnal and nocturnal patterns of activity in mammals. In both groups of animals, the suprachiasmatic nucleus (SCN) functions as the principal circadian pacemaker, and sur...

journal_title：Journal of biological rhythms

authors： Nunez AA,Bult A,McElhinny TL,Smale L

更新日期：1999-08-01 00:00:00

abstract：:The adjustment of hamsters to advanced light-dark (LD) cycles can be greatly accelerated by scheduling a single 3-hr bout of extra activity in a novel running wheel, starting about 7 hr before the time when the animals become active in the preceding LD cycle. The present experiments were designed to provide stronger e...

journal_title：Journal of biological rhythms

authors： Mrosovsky N

更新日期：1989-10-01 00:00:00

abstract：:Abstract The cyanobacterial clock protein KaiC regulates the circadian cycle by exhibiting rhythms in transcription, translation, and phosphorylation. KaiC phosphorylation persists in circadian cycling even under transcription-less conditions and was reconstituted in vitro by incubating KaiC, KaiA, and KaiB. This pres...

journal_title：Journal of biological rhythms

authors： Takigawa-Imamura H,Mochizuki A

更新日期：2006-10-01 00:00:00

abstract：:The authors examined spatial working memory in the Morris water maze during the activity and rest periods of Wistar rats. Wheel-running activity was measured continuously as a marker of circadian phase. To minimize possible masking effects on performance, animals were placed in constant dim light the day before testin...

journal_title：Journal of biological rhythms

authors： Valentinuzzi VS,Menna-Barreto L,Xavier GF

更新日期：2004-08-01 00:00:00

abstract：:In many animals, the circadian clock plays a role in adapting to the coming season by measuring day length. The mechanism for measuring day length and its neuronal circuits remains elusive, however. Under laboratory conditions, the fruit fly, Drosophila melanogaster, displays 2 activity peaks: one in the morning and o...

journal_title：Journal of biological rhythms

authors： Kistenpfennig C,Nakayama M,Nihara R,Tomioka K,Helfrich-Förster C,Yoshii T

更新日期：2018-02-01 00:00:00

abstract：:Mice homozygous for a dominant-negative allele of the Clock gene (Clock (Δ19/Δ19)) have slightly but significantly decreased male fertility. The molecular mechanism for this reduction in fertility is unknown. In the present study, we used a small hairpin RNA (shRNA) strategy to specifically knock down the Clock gene e...

journal_title：Journal of biological rhythms

authors： Liang X,Cheng S,Jiang X,He X,Wang Y,Jiang Z,Hou W,Li S,Liu Y,Wang Z

更新日期：2013-06-01 00:00:00

abstract：:A 24-h treatment with the cytokine tumor necrosis factor-alpha (TNF-alpha) suppresses transcription of E-box-driven clock genes (D-site albumin promoter binding protein, Dbp; Tyrotroph embryonic factor, Tef ; Hepatic leukemia factor, Hlf; Period homolog to Drosophila 1/2/3, Per1, Per2, and Per3) by yet unknown molecul...

journal_title：Journal of biological rhythms

authors： Petrzilka S,Taraborrelli C,Cavadini G,Fontana A,Birchler T

更新日期：2009-08-01 00:00:00

abstract：:Most visual system functions, such as opsin gene expression, retinal neural transmission, light perception, and visual sensitivity, display robust day-night rhythms. The rhythms persist in constant lighting conditions, suggesting the involvement of endogenous circadian clocks. While the circadian pacemakers that contr...

journal_title：Journal of biological rhythms

authors： Li L

更新日期：2019-10-01 00:00:00

abstract：:Ground squirrels, Spermophilus tridecemlineatus, were kept in a 12:12 h light-dark cycle. As expected for a diurnal species, their locomotor activity occurred almost entirely in the daytime. Expression of mPer1 and mPer2 in the suprachiasmatic nucleus was studied at six time points by in situ hybridization. For both t...

journal_title：Journal of biological rhythms

authors： Mrosovsky N,Edelstein K,Hastings MH,Maywood ES

更新日期：2001-10-01 00:00:00

abstract：:The ventral subparaventricular zone (vSPVZ) receives direct retinal input and influences the daily patterning of activity in rodents, making it a likely candidate for the mediation of acute behavioral responses to light (i.e., masking). We performed chemical lesions aimed at the vSPVZ of diurnal grass rats (Arvicanthi...

journal_title：Journal of biological rhythms

authors： Gall AJ,Shuboni DD,Yan L,Nunez AA,Smale L

更新日期：2016-04-01 00:00:00

abstract：:Hibernating animals have been a successful model system for elucidating fundamental properties of many physiological systems. Over the past 50 years, a diverse literature has emerged on the role of the circadian system in control and expression of winter torpor in several orders of birds and mammals. This body of rese...

journal_title：Journal of biological rhythms

authors： Ruby NF

更新日期：2003-08-01 00:00:00

abstract：:Access to electric light might have shifted the ancestral timing and duration of human sleep. To test this hypothesis, we studied two communities of the historically hunter-gatherer indigenous Toba/Qom in the Argentinean Chaco. These communities share the same ethnic and sociocultural background, but one has free acce...

journal_title：Journal of biological rhythms

authors： de la Iglesia HO,Fernández-Duque E,Golombek DA,Lanza N,Duffy JF,Czeisler CA,Valeggia CR

更新日期：2015-08-01 00:00:00

abstract：:Social jetlag represents the discrepancy between circadian and social clocks, which is measured as the difference in hours in midpoint of sleep between work days and free days. Previous studies have shown social jetlag to be associated with body mass index (BMI), glycated hemoglobin levels, heart rate, depressive symp...

journal_title：Journal of biological rhythms

authors： Rutters F,Lemmens SG,Adam TC,Bremmer MA,Elders PJ,Nijpels G,Dekker JM

更新日期：2014-10-01 00:00:00

abstract：:Although pineal "synaptic" ribbons (SR) are frequently examined by means of quantitative electron microscopy, their functional significance remains unclear. The same is true for related structures--"synaptic" spherules (SPH). In the course of such studies, it has been noted that SR counts may differ from laboratory to...

journal_title：Journal of biological rhythms

authors： Karasek M,Lewinski A,Vollrath L

更新日期：1988-04-01 00:00:00

abstract：:The Drosophila clock relies on transcriptional feedback loops that generate daily oscillations of the clock gene expression at mRNA and protein levels. In the evening, the CLOCK (CLK) and CYCLE (CYC) basic helix-loop-helix (bHLH) PAS-domain transcription factors activate the expression of the period (per) and timeless...

journal_title：Journal of biological rhythms

authors： Richier B,Michard-Vanhée C,Lamouroux A,Papin C,Rouyer F

更新日期：2008-04-01 00:00:00

abstract：:Daylight saving time (DST) is a source of circadian disruption impinging on millions of people every year. Our aim was to assess modifications, if any, in the number, type, and outcome of Accident & Emergency (A&E) visits/return visits over the DST months. The study included 366,527 visits and 84,380 return visits to ...

journal_title：Journal of biological rhythms

authors： Ferrazzi E,Romualdi C,Ocello M,Frighetto G,Turco M,Vigolo S,Fabris F,Angeli P,Vettore G,Costa R,Montagnese S

更新日期：2018-10-01 00:00:00

abstract：:DEC1 and DEC2-basic helix-loop-helix transcription factors-exhibit a circadian expression in the suprachiasmatic nucleus and other peripheral tissues and seem to play roles in regulating the mammalian circadian rhythm by suppressing the CLOCK/BMAL1-activated promoters of Per1, Dec1, and Dec2. The authors present data ...

journal_title：Journal of biological rhythms

authors： Noshiro M,Furukawa M,Honma S,Kawamoto T,Hamada T,Honma K,Kato Y

更新日期：2005-10-01 00:00:00

abstract：:The circadian clock represents an anticipatory mechanism, well preserved in evolution. It has a critical impact on most aspects of the physiology of light-sensitive organisms. These rhythmic processes are governed by environmental cues (fluctuations in light intensity and temperature), an internal circadian timing sys...

journal_title：Journal of biological rhythms

authors： Philippe J,Dibner C

更新日期：2015-04-01 00:00:00

abstract：:Female Drosophila melanogaster, like many other organisms, exhibit different behavioral repertoires after mating with a male. These postmating responses (PMRs) include increased egg production and laying, increased rejection behavior (avoiding further male advances), decreased longevity, altered gustation and decrease...

journal_title：Journal of biological rhythms

authors： Garbe DS,Vigderman AS,Moscato E,Dove AE,Vecsey CG,Kayser MS,Sehgal A

更新日期：2016-12-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) drives circadian rhythms in locomotion through coupled, single-cell oscillations. Global genetic deletion of the neuropeptide Vip or its receptor Vipr2 results in profound deficits in daily synchrony among SCN cells and daily rhythms in locomotor behavior and glucocorticoid secretion....

journal_title：Journal of biological rhythms

authors： Mazuski C,Chen SP,Herzog ED

更新日期：2020-10-01 00:00:00

abstract：:The authors sought to investigate the role of phytochromes A and B (phyA and phyB) and cryptochromes 1 and 2 (cryl and cry2) in the synchronization of the leaf position rhythm in Arabidopsis thaliana. The seedlings were transferred from white light-dark cycles to free-running conditions with or without exposure to a l...

journal_title：Journal of biological rhythms

authors： Yanovsky MJ,Mazzella MA,Whitelam GC,Casal JJ

更新日期：2001-12-01 00:00:00

abstract：:Endogenous circadian rhythms are involved in various photoperiodic responses of birds. Investigations involving the mechanisms of photoperiodic time measurement in birds have been confined mainly to temperate zone species using males exclusively. Due to the paucity of experimental evidence on subtropical birds that ha...

journal_title：Journal of biological rhythms

authors： Ravikumar G,Senthilkumaran B,Tewary PD,Goel AK

更新日期：1995-12-01 00:00:00

abstract：:The temporal expression pattern of the circadian clock gene period was compared between heads of the linden bug, Pyrrhocoris apterus , kept under diapause-promoting short days (SD) and diapause-preventing long days (LD) using a real-time PCR quantification. Diapause or reproduction was programmed by photoperiod during...

journal_title：Journal of biological rhythms

authors： Dolezel D,Sauman I,Kost'ál V,Hodkova M

更新日期：2007-08-01 00:00:00