Is social jetlag associated with an adverse endocrine, behavioral, and cardiovascular risk profile?

abstract：:Melatonin is secreted systemically from the pineal gland maximally at night but is also produced locally in many tissues. Its chronobiological function is mainly exerted by pineal melatonin. It is a feedback regulator of the main circadian pacemaker in the hypothalamic suprachiasmatic nuclei and of many peripheral osc...

journal_title：Journal of biological rhythms

authors： Slawik H,Stoffel M,Riedl L,Veselý Z,Behr M,Lehmberg J,Pohl C,Meyer B,Wiegand M,Krieg SM

更新日期：2016-02-01 00:00:00

abstract：:Although pineal "synaptic" ribbons (SR) are frequently examined by means of quantitative electron microscopy, their functional significance remains unclear. The same is true for related structures--"synaptic" spherules (SPH). In the course of such studies, it has been noted that SR counts may differ from laboratory to...

journal_title：Journal of biological rhythms

authors： Karasek M,Lewinski A,Vollrath L

更新日期：1988-04-01 00:00:00

abstract：:An intricate transcription-translation feedback loop (TTFL) governs cellular circadian rhythms in mammals. Here, we report that the zinc finger transcription factor Krüppel-like factor 9 (KLF9) is regulated by this TTFL, it associates in chromatin at the core circadian clock and clock-output genes, and it acts to modu...

journal_title：Journal of biological rhythms

authors： Knoedler JR,Ávila-Mendoza J,Subramani A,Denver RJ

更新日期：2020-06-01 00:00:00

abstract：:House sparrows (Passer domesticus) whose circadian rhythms of locomotor activity and feeding had been abolished by pinealectomy were held in constant dim light and periodically exposed to melatonin in the drinking water. By alternating 8 h of melatonin water with variable phases of tap water, rhythms with periods (T) ...

journal_title：Journal of biological rhythms

authors： Heigl S,Gwinner E

更新日期：1995-09-01 00:00:00

abstract：:Groups of Syrian hamsters were exposed to LD cycles with twilight transitions and photoperiods simulating natural lighting conditions at the summer solstice (SS), equinox, and winter solstice (WS) at 41 degrees N and at the winter solstice at the Arctic Circle (WS 66 degrees N) but with daytime illuminance truncated a...

journal_title：Journal of biological rhythms

authors： Boulos Z,Macchi MM

更新日期：2005-04-01 00:00:00

abstract：:The tau mutation in Syrian hamsters (Mesocricetus auratus) is phenotypically expressed in a period of the circadian rhythm of about 20 h in homozygotes (SS) and about 22 h in heterozygotes (S+). The authors investigate whether this well-defined model for variation in circadian period exhibits associated changes in ene...

journal_title：Journal of biological rhythms

authors： Oklejewicz M,Hut RA,Daan S,Loudon AS,Stirland AJ

更新日期：1997-10-01 00:00:00

abstract：:The frequency demultiplication hypothesis (FDH) posits that circannual rhythms are generated from circadian cycles by frequency transformation to the lower-frequency rhythm. To test the FDH, we determined the periods of the circannual body mass and estrous cycles of golden-mantled ground squirrels with circadian locom...

journal_title：Journal of biological rhythms

authors： Carmichael MS,Zucker I

更新日期：1986-01-01 00:00:00

abstract：:In vertebrates, reproductive output often increases with age. Unlike older birds, first-year photoperiodic birds lack experience with the reproductively stimulatory effects of long day lengths (photostimulation). We examined whether age-related differences in annual reproductive development could be partially attribut...

journal_title：Journal of biological rhythms

authors： Salvante KG,Dawson A,Aldredge RA,Sharp PJ,Sockman KW

更新日期：2013-02-01 00:00:00

abstract：:Morningness and eveningness preference, an endogenous component of the circadian clock, is characterized by an interindividual difference in circadian phase and requires of humans a specific timing of behavior. The biological rhythms of morning and evening types are consequently phase shifted with fixed socioeconomic ...

journal_title：Journal of biological rhythms

authors： Taillard J,Philip P,Chastang JF,Diefenbach K,Bioulac B

更新日期：2001-04-01 00:00:00

abstract：:Sex differences in circadian rhythms have been reported with some conflicting results. The timing of sleep and length of time in bed have not been considered, however, in previous such studies. The current study has 3 major aims: (1) replicate previous studies in a large sample of young adults for sex differences in s...

journal_title：Journal of biological rhythms

authors： Van Reen E,Sharkey KM,Roane BM,Barker D,Seifer R,Raffray T,Bond TL,Carskadon MA

更新日期：2013-12-01 00:00:00

abstract：:A rhythm mutant of Drosophila melanogaster was induced by chemical mutagenesis and isolated by testing for locomotor activity rhythms, which in the new variant had periods of approximately 16 hr. The sex-linked mutation responsible for this ultrashort period causes 20-hr rhythms when heterozygous with a normal X. This...

journal_title：Journal of biological rhythms

authors： Konopka RJ,Hamblen-Coyle MJ,Jamison CF,Hall JC

更新日期：1994-01-01 00:00:00

abstract：:Obesity during pregnancy causes numerous maternal and fetal health complications, but the underlying mechanisms remain unclear. Adipose tissue dysfunction in obesity has previously been linked to disruption of the intrinsic adipose clock gene network that is crucial for normal metabolic function. This adipose clock al...

journal_title：Journal of biological rhythms

authors： Crew RC,Mark PJ,Waddell BJ

更新日期：2018-06-01 00:00:00

abstract：:Extracellular spike activity from three different types of visual interneurons found in the optic lobe of the giant cockroach Blaberus giganteus was recorded. The spike rate of all three types of neurons fluctuated in a circadian manner in constant darkness (DD). Two types, so-called "on" neurons (ON1 and ON2), respon...

journal_title：Journal of biological rhythms

authors： Bult R,Mastebroek HA

更新日期：1993-01-01 00:00:00

abstract：:Numerous studies have used the classic van der Pol oscillator, which contains a cubic nonlinearity, to model the effect of light on the human circadian pacemaker. Jewett and Kronauer demonstrated that Aschoff's rule could be incorporated into van der Pol type models and used a van der Pol type oscillator with higher o...

journal_title：Journal of biological rhythms

authors： Forger DB,Jewett ME,Kronauer RE

更新日期：1999-12-01 00:00:00

abstract：:A physiologically based mathematical model of a putative sleep-wake regulatory network is used to investigate the transition from typical human sleep patterns to spontaneous internal desynchrony behavior observed under temporal isolation conditions. The model sleep-wake regulatory network describes the neurotransmitte...

journal_title：Journal of biological rhythms

authors： Gleit RD,Diniz Behn CG,Booth V

更新日期：2013-10-01 00:00:00

abstract：:The pineal organ of the lizard Anolis carolinensis acts as a transducer of photoperiodic information, since light can affect the pineal melatonin rhythm (PMR). The synthesis and secretion of melatonin may be a major mechanism whereby a circadian pacemaker within the pineal can control circadian clocks located elsewher...

journal_title：Journal of biological rhythms

authors： Underwood H,Calaban M

更新日期：1987-10-01 00:00:00

abstract：:Access to electric light might have shifted the ancestral timing and duration of human sleep. To test this hypothesis, we studied two communities of the historically hunter-gatherer indigenous Toba/Qom in the Argentinean Chaco. These communities share the same ethnic and sociocultural background, but one has free acce...

journal_title：Journal of biological rhythms

authors： de la Iglesia HO,Fernández-Duque E,Golombek DA,Lanza N,Duffy JF,Czeisler CA,Valeggia CR

更新日期：2015-08-01 00:00:00

abstract：:A role for nitric oxide in circadian responses to light has been indicated in previous studies. To determine the specific function of NO-, the authors manipulated NO- and nitric oxide synthase (NOS) activity prior to light pulses that would normally induce phase shifts. The NOS inhibitor, L-NAME, selectively attenuate...

journal_title：Journal of biological rhythms

authors： Melo L,Golombek DA,Ralph MR

更新日期：1997-08-01 00:00:00

abstract：:Whether the circatidal rhythm is generated by a machinery common to the circadian clock is one of the important and interesting questions in chronobiology. The mangrove cricket Apteronemobius asahinai shows a circatidal rhythm generating active and inactive phases and a circadian rhythm modifying the circatidal rhythm...

journal_title：Journal of biological rhythms

authors： Takekata H,Numata H,Shiga S

更新日期：2014-02-01 00:00:00

abstract：:African sleeping sickness is characterized by alterations in rhythmic functions. It is not known if the disease affects the expression of clock genes, which are the molecular basis for rhythm generation. We used a chronic rat model of experimental sleeping sickness, caused by the extracellular parasite Trypanosoma bru...

journal_title：Journal of biological rhythms

authors： Lundkvist GB,Sellix MT,Nygård M,Davis E,Straume M,Kristensson K,Block GD

更新日期：2010-04-01 00:00:00

abstract：:From the mathematical study of simple models for circadian rhythm, the authors identified a clear effect of saturation in the enzyme kinetics on the promotion or suppression of a sustained oscillation. In the models, a clock gene (per gene) is transcribed to produce mRNAs, which are translated to produce proteins in t...

journal_title：Journal of biological rhythms

authors： Kurosawa G,Iwasa Y

更新日期：2002-12-01 00:00:00

abstract：:The authors have shown previously that vasopressin (VP) release from suprachiasmatic nucleus (SCN) efferents in rats is important for the timing of the circadian activity of the hypothalamo-pituitary-adrenal (HPA) axis, resulting in a circadian rise in corticosterone at dusk. When meals are supplied at a fixed time du...

journal_title：Journal of biological rhythms

authors： Kalsbeek A,van Heerikhuize JJ,Wortel J,Buijs RM

更新日期：1998-02-01 00:00:00

abstract：:A 24-h treatment with the cytokine tumor necrosis factor-alpha (TNF-alpha) suppresses transcription of E-box-driven clock genes (D-site albumin promoter binding protein, Dbp; Tyrotroph embryonic factor, Tef ; Hepatic leukemia factor, Hlf; Period homolog to Drosophila 1/2/3, Per1, Per2, and Per3) by yet unknown molecul...

journal_title：Journal of biological rhythms

authors： Petrzilka S,Taraborrelli C,Cavadini G,Fontana A,Birchler T

更新日期：2009-08-01 00:00:00

abstract：:Siberian hamsters are photoperiodic seasonally breeding rodents. To date, there has been no evidence that Siberian hamsters exhibit an annual rhythm in reproductive, thermoregulatory, molt, or body mass changes. However, given that the termination of their winter cycle is under endogenous control, the authors thought ...

journal_title：Journal of biological rhythms

authors： Anchordoquy HC,Lynch GR

更新日期：2000-04-01 00:00:00

abstract：:On the southern Iberian Peninsula, the seasonal life history of the large white butterfly, Pieris brassicae, comprises 2 different photoperiodically induced developmental arrests: a hibernation diapause at photophases < 11 h and an estivation diapause at photophases > 14 h. At intermediate photophases (12 h to 13 h), ...

journal_title：Journal of biological rhythms

authors： Spieth HR,Xue F,Strau K

更新日期：2004-12-01 00:00:00

abstract：:Various aspects of mammalian endocrine physiology show a time-of-day variation with a period of 24 h, which represents an adaptation to the daily environmental fluctuations resulting from the rotation of the earth. These 24-h rhythms in hormone abundance and consequently hormone function may rely on rhythmic signals p...

journal_title：Journal of biological rhythms

authors： Lin XW,Blum ID,Storch KF

更新日期：2015-08-01 00:00:00

abstract：:Sleep disturbances are an all-too-familiar symptom of jet lag and a prime source of complaints for transmeridian travelers and flight crews alike. They are the result of a temporary loss of synchrony between an abruptly shifted sleep period, timed in accordance with the new local day-night cycle, and a gradually reent...

journal_title：Journal of biological rhythms

authors： Boulos Z,Campbell SS,Lewy AJ,Terman M,Dijk DJ,Eastman CI

更新日期：1995-06-01 00:00:00

abstract：:Numerous studies have demonstrated sleep-promoting effects of melatonin treatment in humans, as evidenced by subjects' self-reports, polysomnographic recordings, and continuous actigraphic registration of motor activity. The sleep-promoting effects of either physiological or pharmacological doses of melatonin typicall...

journal_title：Journal of biological rhythms

authors： Zhdanova IV,Wurtman RJ

更新日期：1997-12-01 00:00:00

abstract：:The adjustment of hamsters to advanced light-dark (LD) cycles can be greatly accelerated by scheduling a single 3-hr bout of extra activity in a novel running wheel, starting about 7 hr before the time when the animals become active in the preceding LD cycle. The present experiments were designed to provide stronger e...

journal_title：Journal of biological rhythms

authors： Mrosovsky N

更新日期：1989-10-01 00:00:00

abstract：:The safety and efficacy of chemotherapeutics can vary as a function of the time of their delivery during the day. This study aimed to improve the treatment of glioblastoma (GBM), the most common brain cancer, by testing whether the efficacy of the DNA alkylator temozolomide (TMZ) varies with the time of its administra...

journal_title：Journal of biological rhythms

authors： Slat EA,Sponagel J,Marpegan L,Simon T,Kfoury N,Kim A,Binz A,Herzog ED,Rubin JB

更新日期：2017-04-01 00:00:00