Nonphotic enhancement of adjustment to new light-dark cycles: masking interpretation discounted.

abstract：:Over 90% of neurons within the suprachiasmatic nucleus (SCN) express γ-aminobutyric acid (GABA). Although GABA is primarily an inhibitory neurotransmitter, in vitro studies suggest that the activation of GABAA receptors (GABAAR) elicits excitation in the adult SCN. The ratio of excitatory to inhibitory responses to GA...

journal_title：Journal of biological rhythms

authors： McNeill JK 4th,Walton JC,Albers HE

更新日期：2018-08-01 00:00:00

abstract：:Temperature compensation of circadian rhythms in neuronal firing rate was investigated in the suprachiasmatic nucleus (SCN) of ground squirrels and rats in vitro. A reduction in SCN temperature from 37 to 25 degrees C reduced peak firing rates by > 70% in rats but only by approximately 21% in squirrels; trough firing ...

journal_title：Journal of biological rhythms

authors： Ruby NF,Heller HC

更新日期：1996-06-01 00:00:00

abstract：:Austrovenus stutchburyi is an intertidal, burrowing, filter-feeding bivalve. It exhibits a strong, approximately tidal pattern in the time of gaping of its valves when in constant laboratory conditions. Individuals that have been held in laboratory conditions long enough to lose their overt gaping pattern will respond...

journal_title：Journal of biological rhythms

authors： Williams BG,Pilditch CA

更新日期：1997-04-01 00:00:00

abstract：:In our attempts to understand the circadian system, we unavoidably rely on abstractions. Instead of describing the behavior of the circadian system in all its complexity, we try to derive basic features from which we form a global concept on how the system works. Such a basic concept is a model of reality. The author ...

journal_title：Journal of biological rhythms

authors： Beersma DG

更新日期：2005-08-01 00:00:00

abstract：:Rats anticipate a fixed daily feeding time by entrainment of a component of their multioscillatory circadian system. The range of stimuli capable of entraining this component is little studied. Previous studies suggest that restricted water access is not an effective entrainment stimulus, as measured by general locomo...

journal_title：Journal of biological rhythms

authors： Mistlberger RE

更新日期：1992-07-01 00:00:00

abstract：:Testicular growth was monitored in male ferrets subjected to one of the following photoperiodic treatments begun at weaning (8 weeks of age): 8 hr light/day (short days), 18 hr light/day (long days), or short days followed by transition to long days at either 10, 12, or 14 weeks of age. Mean ages to achieve adult test...

journal_title：Journal of biological rhythms

authors： Sisk CL

更新日期：1990-10-01 00:00:00

abstract：:The mammalian circadian clock is known to be entrained by both a daily light-dark cycle and daily feeding cycle. However, the mechanisms of feeding-induced entrainment are not as fully understood as those of light entrainment. To elucidate the first step of entrainment of the liver clock, we identified the circadian c...

journal_title：Journal of biological rhythms

authors： Tahara Y,Otsuka M,Fuse Y,Hirao A,Shibata S

更新日期：2011-06-01 00:00:00

abstract：:Numerous studies have demonstrated sleep-promoting effects of melatonin treatment in humans, as evidenced by subjects' self-reports, polysomnographic recordings, and continuous actigraphic registration of motor activity. The sleep-promoting effects of either physiological or pharmacological doses of melatonin typicall...

journal_title：Journal of biological rhythms

authors： Zhdanova IV,Wurtman RJ

更新日期：1997-12-01 00:00:00

abstract：:An understanding of the retinal mechanisms in mammalian photoentrainment will greatly facilitate optimization of the wavelength, intensity, and duration of phototherapeutic treatments designed to phase shift endogenous biological rhythms. A small population of widely dispersed retinal ganglion cells projecting to the ...

journal_title：Journal of biological rhythms

authors： Rollag MD,Berson DM,Provencio I

更新日期：2003-06-01 00:00:00

abstract：:Surgical isolation of the suprachiasmatic nuclei (SCN) within a hypothalamic island is reported to produce loss of circadian rhythmicity. The results have been interpreted to indicate that SCN efferents are necessary for the expression of circadian rhythms. It is not clear, however, whether the loss of circadian rhyth...

journal_title：Journal of biological rhythms

authors： Hakim H,DeBernardo AP,Silver R

更新日期：1991-07-01 00:00:00

abstract：:Male rose-ringed parakeets (Psittacula krameri) were transferred to a long photoperiod (LP; LD 16:8) or a short photoperiod (SP; LD 8:16) for 45 or 90 days on four dates corresponding to the beginnings of different reproductive phases in an annual testicular cycle, and testicular responsiveness was evaluated by compar...

journal_title：Journal of biological rhythms

authors： Maitra SK,Dey M

更新日期：1992-04-01 00:00:00

abstract：:Despite the omnipresence of artificial and natural light exposure, there exists little guidance in the United States and elsewhere on light exposure in terms of timing, intensity, spectrum, and other light characteristics known to affect human health, performance, and well-being; in parallel, there is little informati...

journal_title：Journal of biological rhythms

authors： Mason IC,Boubekri M,Figueiro MG,Hasler BP,Hattar S,Hill SM,Nelson RJ,Sharkey KM,Wright KP,Boyd WA,Brown MK,Laposky AD,Twery MJ,Zee PC

更新日期：2018-10-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) drives and synchronizes daily rhythms at the cellular level via transcriptional-translational feedback loops comprising clock genes such as Bmal1 and Period (Per). Glycogen synthase kinase 3 (GSK3), a serine/threonine kinase, phosphorylates at least 5 core clock proteins and shows diu...

journal_title：Journal of biological rhythms

authors： Besing RC,Paul JR,Hablitz LM,Rogers CO,Johnson RL,Young ME,Gamble KL

更新日期：2015-04-01 00:00:00

abstract：:Odors elicit a number of behavioral responses, including attraction and repulsion in Drosophila. In this study, the authors used a T-maze apparatus to show that wild-type Drosophila melanogaster exhibit a robust circadian rhythm in the olfactory attractive and repulsive responses. These responses were lower during the...

journal_title：Journal of biological rhythms

authors： Zhou X,Yuan C,Guo A

更新日期：2005-06-01 00:00:00

abstract：:A physiologically based mathematical model of a putative sleep-wake regulatory network is used to investigate the transition from typical human sleep patterns to spontaneous internal desynchrony behavior observed under temporal isolation conditions. The model sleep-wake regulatory network describes the neurotransmitte...

journal_title：Journal of biological rhythms

authors： Gleit RD,Diniz Behn CG,Booth V

更新日期：2013-10-01 00:00:00

abstract：:Nonphotic stimuli can reset and entrain circadian activity rhythms in hamsters and mice, and serotonin is thought to be involved in the phase-resetting effects of these stimuli. In the present study, the authors examined the effect of the serotonin agonist quipazine on circadian activity rhythms in three inbred strain...

journal_title：Journal of biological rhythms

authors： Kohler M,Kalkowski A,Wollnik F

更新日期：1999-04-01 00:00:00

abstract：:In mammals, the suprachiasmatic nucleus (SCN) is the central pacemaker organizing circadian rhythms of behavior and physiology. At the cellular level, the mammalian clock consists of autoregulatory feedback loops involving a set of "clock genes," including the Cryptochrome (Cry) genes, Cry1 and Cry2. Experimental evid...

journal_title：Journal of biological rhythms

authors： Evans JA,Pan H,Liu AC,Welsh DK

更新日期：2012-12-01 00:00:00

abstract：:Honey bee workers care for ("nurse") the brood around the clock without circadian rhythmicity, but then they forage outside with strong circadian rhythms and a consolidated nightly rest. This chronobiological plasticity is associated with variation in the expression of the canonical "clock genes" that regulate the cir...

journal_title：Journal of biological rhythms

authors： Rodriguez-Zas SL,Southey BR,Shemesh Y,Rubin EB,Cohen M,Robinson GE,Bloch G

更新日期：2012-02-01 00:00:00

abstract：:The circadian system in higher organisms temporally orchestrates rhythmic changes in a vast number of genes and gene products in different organs. Complex interactions between these components, both within and among cells, ultimately lead to rhythmic behavior and physiology. Identifying the plethora of circadian targe...

journal_title：Journal of biological rhythms

authors： De Haro L,Panda S

更新日期：2006-12-01 00:00:00

abstract：:Two major approaches have been used to model circadian clocks. Qualitative modeling, used prior to the recent wealth of detailed molecular knowledge, makes general predictions but cannot provide detailed mechanistic insights. The more recent biophysical approach, on the other hand, incorporates the biochemical events ...

journal_title：Journal of biological rhythms

authors： Forger D,Gonze D,Virshup D,Welsh DK

更新日期：2007-06-01 00:00:00

abstract：:On the southern Iberian Peninsula, the seasonal life history of the large white butterfly, Pieris brassicae, comprises 2 different photoperiodically induced developmental arrests: a hibernation diapause at photophases < 11 h and an estivation diapause at photophases > 14 h. At intermediate photophases (12 h to 13 h), ...

journal_title：Journal of biological rhythms

authors： Spieth HR,Xue F,Strau K

更新日期：2004-12-01 00:00:00

abstract：:The safety and efficacy of chemotherapeutics can vary as a function of the time of their delivery during the day. This study aimed to improve the treatment of glioblastoma (GBM), the most common brain cancer, by testing whether the efficacy of the DNA alkylator temozolomide (TMZ) varies with the time of its administra...

journal_title：Journal of biological rhythms

authors： Slat EA,Sponagel J,Marpegan L,Simon T,Kfoury N,Kim A,Binz A,Herzog ED,Rubin JB

更新日期：2017-04-01 00:00:00

abstract：:Mice with targeted gene disruption have provided important information about the molecular mechanisms of circadian clock function. A full understanding of the roles of circadian-relevant genes requires manipulation of their expression in a tissue-specific manner, ideally including manipulation with high efficiency wit...

journal_title：Journal of biological rhythms

authors： Weaver DR,van der Vinne V,Giannaris EL,Vajtay TJ,Holloway KL,Anaclet C

更新日期：2018-04-01 00:00:00

abstract：:To determine if a circadian rhythm known to be functionally related to the reproductive axis varies on a circannual basis, we monitored the circadian secretion of melatonin at monthly intervals for 2 years in four ovariectomized, estradiol-implanted ewes held in a constant short-day photoperiod. Prior to the study, ew...

journal_title：Journal of biological rhythms

authors： Thrun LA,Moenter SM,O'Callaghan D,Woodfill CJ,Karsch FJ

更新日期：1995-03-01 00:00:00

abstract：:A rhythm mutant of Drosophila melanogaster was induced by chemical mutagenesis and isolated by testing for locomotor activity rhythms, which in the new variant had periods of approximately 16 hr. The sex-linked mutation responsible for this ultrashort period causes 20-hr rhythms when heterozygous with a normal X. This...

journal_title：Journal of biological rhythms

authors： Konopka RJ,Hamblen-Coyle MJ,Jamison CF,Hall JC

更新日期：1994-01-01 00:00:00

abstract：:Most cyclic biological processes are under control of a circadian molecular timing system that synchronizes these phenomena to the 24-h day. One generic property of circadian-controlled processes is that they operate within a specific temperature range, below which the manifestation of rhythm ceases. Little is known a...

journal_title：Journal of biological rhythms

authors： Maguire SE,Schmidt PS,Sehgal A

更新日期：2014-06-01 00:00:00

abstract：:How the cellular elements of the SCN are synchronized to each other is not well understood. We explore circadian oscillations manifest at the level of the cell, the tissue, and the whole animal to better understand intra-SCN synchrony and master clock function of the nucleus. At each level of analysis, responses to va...

journal_title：Journal of biological rhythms

authors： Butler MP,Silver R

更新日期：2009-10-01 00:00:00

abstract：:Casein kinase 1ε (CK1ε) performs key phosphorylation reactions in the circadian clock mechanism that determine period. We show that the central clock protein PERIOD2 (PER2) not only acts as a transcriptional repressor but also inhibits the autoinactivation of CK1ε, thereby promoting CK1ε activity. Moreover, PER2 recip...

journal_title：Journal of biological rhythms

authors： Qin X,Mori T,Zhang Y,Johnson CH

更新日期：2015-06-01 00:00:00

abstract：:Most of the anatomical and molecular substrates of the system that encodes changes in photoperiod in the duration of melatonin secretion, and the receptor molecules that read this signal, have been shown to be conserved in monkeys and humans, and the functions of this system appear to be intact from the level of the r...

journal_title：Journal of biological rhythms

authors： Wehr TA

更新日期：2001-08-01 00:00:00

abstract：:Since the advent of techniques to investigate gene expression on a large scale, numerous circadian rhythms in mRNA amount have been reported. These rhythms generally differ in amplitude and phase. The authors investigated how far a parameter not regulated by the circadian clock can influence the phase of a rhythm in R...

journal_title：Journal of biological rhythms

authors： Jacobshagen S,Kessler B,Rinehart CA

更新日期：2008-12-01 00:00:00