Systems biology of circadian rhythms: an outlook.

abstract：:Systematic treatment of hamsters with triazolam (TRZ) or novel wheel (NW) access will yield PRCs similar to those for neuropeptide Y. Both TRZ and NW access require an intact intergeniculate leaflet (IGL) to modulate circadian rhythm phase. It is commonly suggested that both stimulus types influence rhythm phase respo...

journal_title：Journal of biological rhythms

authors： Meyer-Bernstein EL,Morin LP

更新日期：1998-12-01 00:00:00

abstract：:Endogenous circadian rhythms are involved in various photoperiodic responses of birds. Investigations involving the mechanisms of photoperiodic time measurement in birds have been confined mainly to temperate zone species using males exclusively. Due to the paucity of experimental evidence on subtropical birds that ha...

journal_title：Journal of biological rhythms

authors： Ravikumar G,Senthilkumaran B,Tewary PD,Goel AK

更新日期：1995-12-01 00:00:00

abstract：:In mammals, the suprachiasmatic nucleus (SCN) is the central pacemaker organizing circadian rhythms of behavior and physiology. At the cellular level, the mammalian clock consists of autoregulatory feedback loops involving a set of "clock genes," including the Cryptochrome (Cry) genes, Cry1 and Cry2. Experimental evid...

journal_title：Journal of biological rhythms

authors： Evans JA,Pan H,Liu AC,Welsh DK

更新日期：2012-12-01 00:00:00

abstract：:The aim of this study was to replicate and extend previous work in which the authors observed lower, shorter, and advanced nocturnal melatonin secretion patterns in premenstrually depressed patients compared to those in healthy control women. The authors also sought to test the hypothesis that the therapeutic effect o...

journal_title：Journal of biological rhythms

authors： Parry BL,Berga SL,Mostofi N,Klauber MR,Resnick A

更新日期：1997-02-01 00:00:00

abstract：:House sparrows (Passer domesticus) whose circadian rhythms of locomotor activity and feeding had been abolished by pinealectomy were held in constant dim light and periodically exposed to melatonin in the drinking water. By alternating 8 h of melatonin water with variable phases of tap water, rhythms with periods (T) ...

journal_title：Journal of biological rhythms

authors： Heigl S,Gwinner E

更新日期：1995-09-01 00:00:00

abstract：:The tau mutation in Syrian hamsters (Mesocricetus auratus) is phenotypically expressed in a period of the circadian rhythm of about 20 h in homozygotes (SS) and about 22 h in heterozygotes (S+). The authors investigate whether this well-defined model for variation in circadian period exhibits associated changes in ene...

journal_title：Journal of biological rhythms

authors： Oklejewicz M,Hut RA,Daan S,Loudon AS,Stirland AJ

更新日期：1997-10-01 00:00:00

abstract：:The mammalian circadian pacemaker is located in the suprachiasmatic nucleus (SCN). Various inputs modulate pacemaker phase, including the serotonergic (5HTergic) input from the midbrain raphe. 5HT phase-advances the SCN pacemaker when applied during mid subjective day. In vitro studies indicate that 5HT advances the m...

journal_title：Journal of biological rhythms

authors： Jovanovska A,Prosser RA

更新日期：2002-04-01 00:00:00

abstract：:The authors sought to investigate the role of phytochromes A and B (phyA and phyB) and cryptochromes 1 and 2 (cryl and cry2) in the synchronization of the leaf position rhythm in Arabidopsis thaliana. The seedlings were transferred from white light-dark cycles to free-running conditions with or without exposure to a l...

journal_title：Journal of biological rhythms

authors： Yanovsky MJ,Mazzella MA,Whitelam GC,Casal JJ

更新日期：2001-12-01 00:00:00

abstract：:Little is known about the differences in the neural substrates of circadian rhythms that are responsible for the maintenance of differences between diurnal and nocturnal patterns of activity in mammals. In both groups of animals, the suprachiasmatic nucleus (SCN) functions as the principal circadian pacemaker, and sur...

journal_title：Journal of biological rhythms

authors： Nunez AA,Bult A,McElhinny TL,Smale L

更新日期：1999-08-01 00:00:00

abstract：:In Drosophila melanogaster, disruption of night by even short light exposures results in degradation of the clock protein TIMELESS (TIM), leading to shifts in the fly molecular and behavioral rhythms. Several lines of evidence indicate that light entrainment of the brain clock involves the blue-light photoreceptor cry...

journal_title：Journal of biological rhythms

authors： Ivanchenko M,Stanewsky R,Giebultowicz JM

更新日期：2001-06-01 00:00:00

abstract：:To assess binocular interactions and possible ocular dominance in entrainment of circadian rhythms, Syrian hamsters maintained in LL were subjected for several weeks to schedules of eye occlusion with opaque contact lenses. In separate groups, the opaque lens was inserted into the left or right eye for 12 h at the sam...

journal_title：Journal of biological rhythms

authors： Park JH,Paul MJ,Butler MP,Zucker I

更新日期：2005-02-01 00:00:00

abstract：:The endogenous circadian rhythm of melatonin in humans provides information regarding the resetting response of the human circadian timing system to changes in the light-dark (LD) cycle. Alterations in the LD cycle have both acute and chronic effects on the observed melatonin rhythm. Investigations to date have firmly...

journal_title：Journal of biological rhythms

authors： Shanahan TL,Zeitzer JM,Czeisler CA

更新日期：1997-12-01 00:00:00

abstract：:Individuals of the shore crab Carcinus maenas were exposed to artificial cycles, applied in tidal antiphase, of pairs of the three major environmental variables that entrain circatidal rhythmicity in this species: salinity, temperature, and hydrostatic pressure. During entrainment, the observed locomotor activity patt...

journal_title：Journal of biological rhythms

authors： Reid DG,Naylor E

更新日期：1990-01-01 00:00:00

abstract：:On the southern Iberian Peninsula, the seasonal life history of the large white butterfly, Pieris brassicae, comprises 2 different photoperiodically induced developmental arrests: a hibernation diapause at photophases < 11 h and an estivation diapause at photophases > 14 h. At intermediate photophases (12 h to 13 h), ...

journal_title：Journal of biological rhythms

authors： Spieth HR,Xue F,Strau K

更新日期：2004-12-01 00:00:00

abstract：:Numerous studies have demonstrated sleep-promoting effects of melatonin treatment in humans, as evidenced by subjects' self-reports, polysomnographic recordings, and continuous actigraphic registration of motor activity. The sleep-promoting effects of either physiological or pharmacological doses of melatonin typicall...

journal_title：Journal of biological rhythms

authors： Zhdanova IV,Wurtman RJ

更新日期：1997-12-01 00:00:00

abstract：:Mice homozygous for a dominant-negative allele of the Clock gene (Clock (Δ19/Δ19)) have slightly but significantly decreased male fertility. The molecular mechanism for this reduction in fertility is unknown. In the present study, we used a small hairpin RNA (shRNA) strategy to specifically knock down the Clock gene e...

journal_title：Journal of biological rhythms

authors： Liang X,Cheng S,Jiang X,He X,Wang Y,Jiang Z,Hou W,Li S,Liu Y,Wang Z

更新日期：2013-06-01 00:00:00

abstract：:The adjustment of hamsters to advanced light-dark (LD) cycles can be greatly accelerated by scheduling a single 3-hr bout of extra activity in a novel running wheel, starting about 7 hr before the time when the animals become active in the preceding LD cycle. The present experiments were designed to provide stronger e...

journal_title：Journal of biological rhythms

authors： Mrosovsky N

更新日期：1989-10-01 00:00:00

abstract：:Extracellular spike activity from three different types of visual interneurons found in the optic lobe of the giant cockroach Blaberus giganteus was recorded. The spike rate of all three types of neurons fluctuated in a circadian manner in constant darkness (DD). Two types, so-called "on" neurons (ON1 and ON2), respon...

journal_title：Journal of biological rhythms

authors： Bult R,Mastebroek HA

更新日期：1993-01-01 00:00:00

abstract：:The temporal expression pattern of the circadian clock gene period was compared between heads of the linden bug, Pyrrhocoris apterus , kept under diapause-promoting short days (SD) and diapause-preventing long days (LD) using a real-time PCR quantification. Diapause or reproduction was programmed by photoperiod during...

journal_title：Journal of biological rhythms

authors： Dolezel D,Sauman I,Kost'ál V,Hodkova M

更新日期：2007-08-01 00:00:00

abstract：:Photoreception in the mammalian retina is not restricted to rods and cones but extends to a small number of intrinsically photosensitive retinal ganglion cells expressing the photopigment melanopsin. These mRGCs are especially important contributors to circadian entrainment, the pupil light reflex, and other so-called...

journal_title：Journal of biological rhythms

authors： Enezi Ja,Revell V,Brown T,Wynne J,Schlangen L,Lucas R

更新日期：2011-08-01 00:00:00

abstract：:Circadian clocks drive daily rhythms of physiology and behavior in multiple organisms and synchronize these rhythms to environmental cycles of light and temperature. The basic mechanism of the clock consists of a transcription-translation feedback loop, in which key clock proteins negatively regulate their own transcr...

journal_title：Journal of biological rhythms

authors： Shakhmantsir I,Sehgal A

更新日期：2019-12-01 00:00:00

abstract：:Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacemaker. For example, cultured astrocytes display circadian rhythms in Period1 and Period2 expression. It is not known, however, how or which intercellular factors synchronize and sustain rhythmicity in astrocytes. Because astrocyt...

journal_title：Journal of biological rhythms

authors： Marpegan L,Krall TJ,Herzog ED

更新日期：2009-04-01 00:00:00

abstract：:Nonphotic stimuli can reset and entrain circadian activity rhythms in hamsters and mice, and serotonin is thought to be involved in the phase-resetting effects of these stimuli. In the present study, the authors examined the effect of the serotonin agonist quipazine on circadian activity rhythms in three inbred strain...

journal_title：Journal of biological rhythms

authors： Kohler M,Kalkowski A,Wollnik F

更新日期：1999-04-01 00:00:00

abstract：:Circadian rhythms are programmed by the suprachiasmatic nucleus (SCN), which relies on neuropeptide signaling to maintain daily timekeeping. Vasoactive intestinal polypeptide (VIP) is critical for SCN function, but the precise role of VIP neurons in SCN circuits is not fully established. To interrogate their contribut...

journal_title：Journal of biological rhythms

authors： Joye DAM,Rohr KE,Keller D,Inda T,Telega A,Pancholi H,Carmona-Alcocer V,Evans JA

更新日期：2020-08-01 00:00:00

abstract：:Photoperiod influences the distribution of sleep and waking and electroencephalogram (EEG) power density in the Djungarian hamster. In an experimental procedure combining short photoperiod (SP) and low ambient temperature, the light-dark difference in the amount of sleep was decreased, and the changes in slow-wave act...

journal_title：Journal of biological rhythms

authors： Deboer T,Vyazovskiy VV,Tobler I

更新日期：2000-10-01 00:00:00

abstract：:Most visual system functions, such as opsin gene expression, retinal neural transmission, light perception, and visual sensitivity, display robust day-night rhythms. The rhythms persist in constant lighting conditions, suggesting the involvement of endogenous circadian clocks. While the circadian pacemakers that contr...

journal_title：Journal of biological rhythms

authors： Li L

更新日期：2019-10-01 00:00:00

abstract：:The mammalian circadian clock in the suprachiasmatic nucleus (SCN) drives and maintains 24-h physiological rhythms, the phases of which are set by the local environmental light-dark cycle. Gastrin-releasing peptide (GRP) communicates photic phase setting signals in the SCN by increasing neurophysiological activity of ...

journal_title：Journal of biological rhythms

authors： Gamble KL,Kudo T,Colwell CS,McMahon DG

更新日期：2011-04-01 00:00:00

abstract：:Rhodopsin 7 ( Rh7), a new invertebrate Rhodopsin gene, was discovered in the genome of Drosophila melanogaster in 2000, but its function has remained elusive. We generated an Rh7 null mutant ( Rh70) by P element-mediated mutagenesis and found that an absence of Rh7 had significant effects on fly activity patterns duri...

journal_title：Journal of biological rhythms

authors： Kistenpfennig C,Grebler R,Ogueta M,Hermann-Luibl C,Schlichting M,Stanewsky R,Senthilan PR,Helfrich-Förster C

更新日期：2017-10-01 00:00:00

abstract：:Sex differences in circadian rhythms have been reported with some conflicting results. The timing of sleep and length of time in bed have not been considered, however, in previous such studies. The current study has 3 major aims: (1) replicate previous studies in a large sample of young adults for sex differences in s...

journal_title：Journal of biological rhythms

authors： Van Reen E,Sharkey KM,Roane BM,Barker D,Seifer R,Raffray T,Bond TL,Carskadon MA

更新日期：2013-12-01 00:00:00

abstract：:An intricate transcription-translation feedback loop (TTFL) governs cellular circadian rhythms in mammals. Here, we report that the zinc finger transcription factor Krüppel-like factor 9 (KLF9) is regulated by this TTFL, it associates in chromatin at the core circadian clock and clock-output genes, and it acts to modu...

journal_title：Journal of biological rhythms

authors： Knoedler JR,Ávila-Mendoza J,Subramani A,Denver RJ

更新日期：2020-06-01 00:00:00