Cycle of period gene expression in a diurnal mammal (Spermophilus tridecemlineatus): implications for nonphotic phase shifting.

Abstract:

:Ground squirrels, Spermophilus tridecemlineatus, were kept in a 12:12 h light-dark cycle. As expected for a diurnal species, their locomotor activity occurred almost entirely in the daytime. Expression of mPer1 and mPer2 in the suprachiasmatic nucleus was studied at six time points by in situ hybridization. For both these genes, mRNA was highest in the first part of the subjective day (about zeitgeber time 5). This is close to the time when mPer1 and mPer2 expression is maximal in nocturnal rodents. These results have implications for understanding nonphotic phase response curves in diurnal species and thereby for guiding research on nonphotic phase shifting in people.

journal_name

J Biol Rhythms

authors

Mrosovsky N,Edelstein K,Hastings MH,Maywood ES

doi

10.1177/074873001129002141

subject

Has Abstract

pub_date

2001-10-01 00:00:00

pages

471-8

issue

5

eissn

0748-7304

issn

1552-4531

journal_volume

16

pub_type

杂志文章
  • A Tug-of-War between Cryptochrome and the Visual System Allows the Adaptation of Evening Activity to Long Photoperiods in Drosophila melanogaster.

    abstract::In many animals, the circadian clock plays a role in adapting to the coming season by measuring day length. The mechanism for measuring day length and its neuronal circuits remains elusive, however. Under laboratory conditions, the fruit fly, Drosophila melanogaster, displays 2 activity peaks: one in the morning and o...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730417738612

    authors: Kistenpfennig C,Nakayama M,Nihara R,Tomioka K,Helfrich-Förster C,Yoshii T

    更新日期:2018-02-01 00:00:00

  • Precise annual changes in the numbers of "synaptic" ribbons and spherules in the rat pineal gland.

    abstract::Although pineal "synaptic" ribbons (SR) are frequently examined by means of quantitative electron microscopy, their functional significance remains unclear. The same is true for related structures--"synaptic" spherules (SPH). In the course of such studies, it has been noted that SR counts may differ from laboratory to...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873048800300103

    authors: Karasek M,Lewinski A,Vollrath L

    更新日期:1988-04-01 00:00:00

  • The visual input stage of the mammalian circadian pacemaking system: I. Is there a clock in the mammalian eye?

    abstract::Threads of evidence from recent experimentation in retinal morphology, neurochemistry, electrophysiology, and visual perception point toward rhythmic ocular processes that may be integral components of circadian entrainment in mammals. Components of retinal cell biology (rod outer-segment disk shedding, inner-segment ...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章,评审

    doi:10.1177/074873049100600104

    authors: Remé CE,Wirz-Justice A,Terman M

    更新日期:1991-04-01 00:00:00

  • Rapid Jetlag Resetting of Behavioral, Physiological, and Molecular Rhythms in Proestrous Female Mice.

    abstract::A gradual adaptation to a shifted light-dark (LD) cycle is a key element of the circadian clock system and believed to be controlled by the central circadian pacemaker, the suprachiasmatic nucleus (SCN). Endocrine factors have a strong influence on the regulation of the circadian clock network and alter acute photic r...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730420965291

    authors: Pilorz V,Kolms B,Oster H

    更新日期:2020-12-01 00:00:00

  • The Paralogous Krüppel-like Factors 9 and 13 Regulate the Mammalian Cellular Circadian Clock Output Gene Dbp.

    abstract::An intricate transcription-translation feedback loop (TTFL) governs cellular circadian rhythms in mammals. Here, we report that the zinc finger transcription factor Krüppel-like factor 9 (KLF9) is regulated by this TTFL, it associates in chromatin at the core circadian clock and clock-output genes, and it acts to modu...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730420913205

    authors: Knoedler JR,Ávila-Mendoza J,Subramani A,Denver RJ

    更新日期:2020-06-01 00:00:00

  • Destruction of serotonergic neurons in the median raphe nucleus blocks circadian rhythm phase shifts to triazolam but not to novel wheel access.

    abstract::Systematic treatment of hamsters with triazolam (TRZ) or novel wheel (NW) access will yield PRCs similar to those for neuropeptide Y. Both TRZ and NW access require an intact intergeniculate leaflet (IGL) to modulate circadian rhythm phase. It is commonly suggested that both stimulus types influence rhythm phase respo...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873098129000327

    authors: Meyer-Bernstein EL,Morin LP

    更新日期:1998-12-01 00:00:00

  • Basis of robustness and resilience in the suprachiasmatic nucleus: individual neurons form nodes in circuits that cycle daily.

    abstract::How the cellular elements of the SCN are synchronized to each other is not well understood. We explore circadian oscillations manifest at the level of the cell, the tissue, and the whole animal to better understand intra-SCN synchrony and master clock function of the nucleus. At each level of analysis, responses to va...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章,评审

    doi:10.1177/0748730409344800

    authors: Butler MP,Silver R

    更新日期:2009-10-01 00:00:00

  • Microarray analysis of natural socially regulated plasticity in circadian rhythms of honey bees.

    abstract::Honey bee workers care for ("nurse") the brood around the clock without circadian rhythmicity, but then they forage outside with strong circadian rhythms and a consolidated nightly rest. This chronobiological plasticity is associated with variation in the expression of the canonical "clock genes" that regulate the cir...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730411431404

    authors: Rodriguez-Zas SL,Southey BR,Shemesh Y,Rubin EB,Cohen M,Robinson GE,Bloch G

    更新日期:2012-02-01 00:00:00

  • Genetic differences in human circadian clock genes among worldwide populations.

    abstract::The daily biological clock regulates the timing of sleep and physiological processes that are of fundamental importance to human health, performance, and well-being. Environmental parameters of relevance to biological clocks include (1) daily fluctuations in light intensity and temperature, and (2) seasonal changes in...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730408320284

    authors: Ciarleglio CM,Ryckman KK,Servick SV,Hida A,Robbins S,Wells N,Hicks J,Larson SA,Wiedermann JP,Carver K,Hamilton N,Kidd KK,Kidd JR,Smith JR,Friedlaender J,McMahon DG,Williams SM,Summar ML,Johnson CH

    更新日期:2008-08-01 00:00:00

  • Flies in the north: locomotor behavior and clock neuron organization of Drosophila montana.

    abstract::The circadian clock plays an important role in adaptation in time and space by synchronizing changes in physiological, developmental, and behavioral traits of organisms with daily and seasonal changes in their environment. We have studied some features of the circadian activity and clock organization in a northern Dro...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730412455916

    authors: Kauranen H,Menegazzi P,Costa R,Helfrich-Förster C,Kankainen A,Hoikkala A

    更新日期:2012-10-01 00:00:00

  • Predicting regulation of the phosphorylation cycle of KaiC clock protein using mathematical analysis.

    abstract::Abstract The cyanobacterial clock protein KaiC regulates the circadian cycle by exhibiting rhythms in transcription, translation, and phosphorylation. KaiC phosphorylation persists in circadian cycling even under transcription-less conditions and was reconstituted in vitro by incubating KaiC, KaiA, and KaiB. This pres...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730406291329

    authors: Takigawa-Imamura H,Mochizuki A

    更新日期:2006-10-01 00:00:00

  • p38 MAP kinase regulates circadian rhythms in Drosophila.

    abstract::The large repertoire of circadian rhythms in diverse organisms depends on oscillating central clock genes, input pathways for entrainment, and output pathways for controlling rhythmic behaviors. Stress-activated p38 MAP Kinases (p38K), although sparsely investigated in this context, show circadian rhythmicity in mamma...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730414555183

    authors: Vrailas-Mortimer AD,Ryan SM,Avey MJ,Mortimer NT,Dowse H,Sanyal S

    更新日期:2014-12-01 00:00:00

  • Predicted microRNAs for mammalian circadian rhythms.

    abstract::There is little evidence for the involvement of microRNAs (miRs) in the regulation of circadian rhythms, despite the potential relevance of these elements in the posttranscriptional regulation of the clock machinery. The present work aimed to identify miRs targeting circadian genes through a predictive analysis of con...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730413476827

    authors: Figueredo Dde S,Barbosa MR,Gitaí DL,de Andrade TG

    更新日期:2013-04-01 00:00:00

  • The circadian clock starts ticking at a developmentally early stage.

    abstract::Although overt diurnal rhythms of behavior do not begin until well after birth, molecular studies suggest that the circadian clock may begin much earlier at a cellular level: mouse embryonic fibroblasts, for example, already possess robust clocks. By multiple criteria, we found no circadian clock present in mouse embr...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730410385281

    authors: Kowalska E,Moriggi E,Bauer C,Dibner C,Brown SA

    更新日期:2010-12-01 00:00:00

  • The circatidal rhythm persists without the optic lobe in the mangrove cricket Apteronemobius asahinai.

    abstract::Whether the circatidal rhythm is generated by a machinery common to the circadian clock is one of the important and interesting questions in chronobiology. The mangrove cricket Apteronemobius asahinai shows a circatidal rhythm generating active and inactive phases and a circadian rhythm modifying the circatidal rhythm...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730413516309

    authors: Takekata H,Numata H,Shiga S

    更新日期:2014-02-01 00:00:00

  • Hibernation: when good clocks go cold.

    abstract::Hibernating animals have been a successful model system for elucidating fundamental properties of many physiological systems. Over the past 50 years, a diverse literature has emerged on the role of the circadian system in control and expression of winter torpor in several orders of birds and mammals. This body of rese...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章,评审

    doi:10.1177/0748730403254971

    authors: Ruby NF

    更新日期:2003-08-01 00:00:00

  • The thalamic intergeniculate leaflet mediates locomotor activity-induced reversal of phenotype in photoperiod nonresponsive Siberian hamsters.

    abstract::The role of the intergeniculate leaflet of the thalamus (IGL) in photoperiod responsiveness was examined in a laboratory-selected line of photoperiod nonresponsive (NR) Siberian hamsters. NR hamsters fail to exhibit typical winter-type responses (i.e., gonadal regression and development of winter-type pelage) when exp...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730406287996

    authors: Freeman DA,Teubner BJ,Goldman BD

    更新日期:2006-06-01 00:00:00

  • Melanopsin, ganglion-cell photoreceptors, and mammalian photoentrainment.

    abstract::An understanding of the retinal mechanisms in mammalian photoentrainment will greatly facilitate optimization of the wavelength, intensity, and duration of phototherapeutic treatments designed to phase shift endogenous biological rhythms. A small population of widely dispersed retinal ganglion cells projecting to the ...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章,评审

    doi:10.1177/0748730403018003005

    authors: Rollag MD,Berson DM,Provencio I

    更新日期:2003-06-01 00:00:00

  • The intergeniculate leaflet partially mediates effects of light on circadian rhythms.

    abstract::Photic signals affect circadian activity rhythms by both phasic and tonic mechanisms that modulate pacemaker phase and period. In mammals, the effects of light on circadian activity are mediated by the retina, which communicates with the suprahiasmatic nucleus (SCN) by two different anatomical routes: the retino-hypot...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873048700200104

    authors: Pickard GE,Ralph MR,Menaker M

    更新日期:1987-04-01 00:00:00

  • Masking and temporal niche switches in spiny mice.

    abstract::Activity patterns are the product of interactions between an internal circadian clock and direct responses to photic and nonphotic features of the environment that are said to "mask" the influence of that clock. Evolutionary transitions between nocturnality and diurnality involve changes in mechanisms underlying both ...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730409351672

    authors: Cohen R,Smale L,Kronfeld-Schor N

    更新日期:2010-02-01 00:00:00

  • Different effects of intensity and duration of locomotor activity on circadian period.

    abstract::An outstanding unresolved issue in chronobiology is how the level of locomotor activity influences length of the free-running, endogenous circadian period (tau). To address this issue, the authors studied a novel model, 4 replicate lines of laboratory house mice (Mus domesticus) that had been selectively bred for high...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730403256998

    authors: Koteja P,Swallow JG,Carter PA,Garland T Jr

    更新日期:2003-12-01 00:00:00

  • Circadian Clocks in the Hematologic System.

    abstract::The hematologic system performs a number of essential functions, including oxygen transport, the execution of the immune response against tumor cells and invading pathogens, and hemostasis (blood clotting). These roles are performed by erythrocytes (red blood cells), leukocytes (white blood cells), and thrombocytes (p...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章,评审

    doi:10.1177/0748730415592729

    authors: Pritchett D,Reddy AB

    更新日期:2015-10-01 00:00:00

  • Food-deprivation-induced phase shifts in Sminthopsis macroura froggatti.

    abstract::Past research has shown that there is a circadian oscillator in laboratory rats that is entrained by restricted feeding schedules. However, in laboratory rats at least, the light-dark (LD) cycle is the dominant zeitgeber in the entrainment of wheel-running activity rhythms. Given that dasyurid marsupials are predomina...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873048900400104

    authors: Coleman GJ,O'Reilly HM,Armstrong SM

    更新日期:1989-04-01 00:00:00

  • Daily rhythms of Fos expression in hypothalamic targets of the suprachiasmatic nucleus in diurnal and nocturnal rodents.

    abstract::Little is known about the differences in the neural substrates of circadian rhythms that are responsible for the maintenance of differences between diurnal and nocturnal patterns of activity in mammals. In both groups of animals, the suprachiasmatic nucleus (SCN) functions as the principal circadian pacemaker, and sur...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873099129000713

    authors: Nunez AA,Bult A,McElhinny TL,Smale L

    更新日期:1999-08-01 00:00:00

  • Systems biology of circadian rhythms: an outlook.

    abstract::The circadian system in higher organisms temporally orchestrates rhythmic changes in a vast number of genes and gene products in different organs. Complex interactions between these components, both within and among cells, ultimately lead to rhythmic behavior and physiology. Identifying the plethora of circadian targe...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730406294767

    authors: De Haro L,Panda S

    更新日期:2006-12-01 00:00:00

  • Differential effects of meal size and food energy density on feeding entrainment in goldfish.

    abstract::The synchronizing stimulus, its transduction site, and the afferent pathways responsible for feeding entrainment remain unknown. In fish, the role of the diet in the development of feeding anticipatory activity (FAA) is not well understood and fundamental questions on the mechanisms of feeding entrainment, such as the...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873040101600107

    authors: Sánchez-Vázquez FJ,Aranda A,Madrid JA

    更新日期:2001-02-01 00:00:00

  • Translational and transcriptional inhibitors block serotonergic phase advances of the suprachiasmatic nucleus circadian pacemaker in vitro.

    abstract::The mammalian circadian pacemaker is located in the suprachiasmatic nucleus (SCN). Various inputs modulate pacemaker phase, including the serotonergic (5HTergic) input from the midbrain raphe. 5HT phase-advances the SCN pacemaker when applied during mid subjective day. In vitro studies indicate that 5HT advances the m...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873002129002429

    authors: Jovanovska A,Prosser RA

    更新日期:2002-04-01 00:00:00

  • Magnesium Regulates the Circadian Oscillator in Cyanobacteria.

    abstract::The circadian clock controls 24-h biological rhythms in our body, influencing many time-related activities such as sleep and wake. The simplest circadian clock is found in cyanobacteria, with the proteins KaiA, KaiB, and KaiC generating a self-sustained circadian oscillation of KaiC phosphorylation and dephosphorylati...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730419851655

    authors: Jeong YM,Dias C,Diekman C,Brochon H,Kim P,Kaur M,Kim YS,Jang HI,Kim YI

    更新日期:2019-08-01 00:00:00

  • At least four distinct circadian regulatory mechanisms are required for all phases of rhythms in mRNA amount.

    abstract::Since the advent of techniques to investigate gene expression on a large scale, numerous circadian rhythms in mRNA amount have been reported. These rhythms generally differ in amplitude and phase. The authors investigated how far a parameter not regulated by the circadian clock can influence the phase of a rhythm in R...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/0748730408325753

    authors: Jacobshagen S,Kessler B,Rinehart CA

    更新日期:2008-12-01 00:00:00

  • Circannual rhythms in starlings: response of castrated birds to 12-hr days depends on photoperiodic history.

    abstract::The annual cycle of reproductive function in starlings (Sturnus vulgaris) is driven by seasonal changes in daylength and consists of a 6-month period of photosensitivity, culminating in maximal gonadal development, followed by a 6-month period of photorefractoriness. If male starlings are held under a constant photope...

    journal_title:Journal of biological rhythms

    pub_type: 杂志文章

    doi:10.1177/074873049300800204

    authors: Dawson A,McNaughton FJ

    更新日期:1993-07-01 00:00:00