Gastrin-releasing peptide modulates fast delayed rectifier potassium current in Per1-expressing SCN neurons.

abstract：:African sleeping sickness is characterized by alterations in rhythmic functions. It is not known if the disease affects the expression of clock genes, which are the molecular basis for rhythm generation. We used a chronic rat model of experimental sleeping sickness, caused by the extracellular parasite Trypanosoma bru...

journal_title：Journal of biological rhythms

authors： Lundkvist GB,Sellix MT,Nygård M,Davis E,Straume M,Kristensson K,Block GD

更新日期：2010-04-01 00:00:00

abstract：:Reduced sensitivity to short-wavelength (blue) light with age has been shown for light-induced melatonin suppression. The current research aimed to determine if a similar age-related reduction occurs in subjective alertness, mood, and circadian phase-advancing responses. Young (n = 11, 23.0 +/- 2.9 years) and older (n...

journal_title：Journal of biological rhythms

authors： Sletten TL,Revell VL,Middleton B,Lederle KA,Skene DJ

更新日期：2009-02-01 00:00:00

abstract：:Since the advent of techniques to investigate gene expression on a large scale, numerous circadian rhythms in mRNA amount have been reported. These rhythms generally differ in amplitude and phase. The authors investigated how far a parameter not regulated by the circadian clock can influence the phase of a rhythm in R...

journal_title：Journal of biological rhythms

authors： Jacobshagen S,Kessler B,Rinehart CA

更新日期：2008-12-01 00:00:00

abstract：:Austrovenus stutchburyi is an intertidal, burrowing, filter-feeding bivalve. It exhibits a strong, approximately tidal pattern in the time of gaping of its valves when in constant laboratory conditions. Individuals that have been held in laboratory conditions long enough to lose their overt gaping pattern will respond...

journal_title：Journal of biological rhythms

authors： Williams BG,Pilditch CA

更新日期：1997-04-01 00:00:00

abstract：:Perhaps the most observable of the many circadian oscillations that have been described in both vertebrate and invertebrate animals is the daily alterations in periods of rest and activity. Recent studies in the fruit fly Drosophila melanogaster suggest that these periods of inactivity are not simply rest but share ma...

journal_title：Journal of biological rhythms

authors： Shaw P

更新日期：2003-02-01 00:00:00

abstract：:A role for nitric oxide in circadian responses to light has been indicated in previous studies. To determine the specific function of NO-, the authors manipulated NO- and nitric oxide synthase (NOS) activity prior to light pulses that would normally induce phase shifts. The NOS inhibitor, L-NAME, selectively attenuate...

journal_title：Journal of biological rhythms

authors： Melo L,Golombek DA,Ralph MR

更新日期：1997-08-01 00:00:00

abstract：:A 12-hr dark period, at a temperature high enough to permit time measurement to occur, is necessary for maximal induction of larval diapause in the European corn borer, Ostrinia nubilalis. In the present study, induction of diapause only occurred in a periodic environment. This was in the form of certain (1) light-dar...

journal_title：Journal of biological rhythms

authors： Skopik SD,Cain W,Patel NG,Newswanger DL

更新日期：1986-07-01 00:00:00

abstract：:A physiologically based mathematical model of a putative sleep-wake regulatory network is used to investigate the transition from typical human sleep patterns to spontaneous internal desynchrony behavior observed under temporal isolation conditions. The model sleep-wake regulatory network describes the neurotransmitte...

journal_title：Journal of biological rhythms

authors： Gleit RD,Diniz Behn CG,Booth V

更新日期：2013-10-01 00:00:00

abstract：:Testicular growth was monitored in male ferrets subjected to one of the following photoperiodic treatments begun at weaning (8 weeks of age): 8 hr light/day (short days), 18 hr light/day (long days), or short days followed by transition to long days at either 10, 12, or 14 weeks of age. Mean ages to achieve adult test...

journal_title：Journal of biological rhythms

authors： Sisk CL

更新日期：1990-10-01 00:00:00

abstract：:Temperature compensation of circadian rhythms in neuronal firing rate was investigated in the suprachiasmatic nucleus (SCN) of ground squirrels and rats in vitro. A reduction in SCN temperature from 37 to 25 degrees C reduced peak firing rates by > 70% in rats but only by approximately 21% in squirrels; trough firing ...

journal_title：Journal of biological rhythms

authors： Ruby NF,Heller HC

更新日期：1996-06-01 00:00:00

abstract：:Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacemaker. For example, cultured astrocytes display circadian rhythms in Period1 and Period2 expression. It is not known, however, how or which intercellular factors synchronize and sustain rhythmicity in astrocytes. Because astrocyt...

journal_title：Journal of biological rhythms

authors： Marpegan L,Krall TJ,Herzog ED

更新日期：2009-04-01 00:00:00

abstract：:In many animals, the circadian clock plays a role in adapting to the coming season by measuring day length. The mechanism for measuring day length and its neuronal circuits remains elusive, however. Under laboratory conditions, the fruit fly, Drosophila melanogaster, displays 2 activity peaks: one in the morning and o...

journal_title：Journal of biological rhythms

authors： Kistenpfennig C,Nakayama M,Nihara R,Tomioka K,Helfrich-Förster C,Yoshii T

更新日期：2018-02-01 00:00:00

abstract：:Mice with targeted gene disruption have provided important information about the molecular mechanisms of circadian clock function. A full understanding of the roles of circadian-relevant genes requires manipulation of their expression in a tissue-specific manner, ideally including manipulation with high efficiency wit...

journal_title：Journal of biological rhythms

authors： Weaver DR,van der Vinne V,Giannaris EL,Vajtay TJ,Holloway KL,Anaclet C

更新日期：2018-04-01 00:00:00

abstract：:The purpose of this study was to determine whether decreased day lengths affect reproduction or the immune system in inbred mice. Irrespective of a nocturnal pineal melatonin rise, the signal for day length information, body and testis weights were the same in various strains 8 weeks after transfer from long to short ...

journal_title：Journal of biological rhythms

authors： Yellon SM,Tran LT

更新日期：2002-02-01 00:00:00

abstract：:The mammalian circadian pacemaker is located in the suprachiasmatic nucleus (SCN). Various inputs modulate pacemaker phase, including the serotonergic (5HTergic) input from the midbrain raphe. 5HT phase-advances the SCN pacemaker when applied during mid subjective day. In vitro studies indicate that 5HT advances the m...

journal_title：Journal of biological rhythms

authors： Jovanovska A,Prosser RA

更新日期：2002-04-01 00:00:00

abstract：:Endogenous circadian rhythms are involved in various photoperiodic responses of birds. Investigations involving the mechanisms of photoperiodic time measurement in birds have been confined mainly to temperate zone species using males exclusively. Due to the paucity of experimental evidence on subtropical birds that ha...

journal_title：Journal of biological rhythms

authors： Ravikumar G,Senthilkumaran B,Tewary PD,Goel AK

更新日期：1995-12-01 00:00:00

abstract：:Honey bee workers care for ("nurse") the brood around the clock without circadian rhythmicity, but then they forage outside with strong circadian rhythms and a consolidated nightly rest. This chronobiological plasticity is associated with variation in the expression of the canonical "clock genes" that regulate the cir...

journal_title：Journal of biological rhythms

authors： Rodriguez-Zas SL,Southey BR,Shemesh Y,Rubin EB,Cohen M,Robinson GE,Bloch G

更新日期：2012-02-01 00:00:00

abstract：:Daylight saving time (DST) is a source of circadian disruption impinging on millions of people every year. Our aim was to assess modifications, if any, in the number, type, and outcome of Accident & Emergency (A&E) visits/return visits over the DST months. The study included 366,527 visits and 84,380 return visits to ...

journal_title：Journal of biological rhythms

authors： Ferrazzi E,Romualdi C,Ocello M,Frighetto G,Turco M,Vigolo S,Fabris F,Angeli P,Vettore G,Costa R,Montagnese S

更新日期：2018-10-01 00:00:00

abstract：:Almost exclusively, photoperiodic insects respond to a given photoperiod in one of two ways: a "long-day" response or a "short-day" response. Intermediate responses occur only at a very restricted range of photoperiods (often less than 30 min) and are generally population phenomena rather than intermediate responses o...

journal_title：Journal of biological rhythms

authors： Wassmer GT,Page TL

更新日期：1993-04-01 00:00:00

abstract：:Siberian hamsters transferred from a long (16 h light/day [16 L]) to an intermediate (13.5 L) day length (DL) undergo testicular regression within 2 months followed approximately 2 months later by "spontaneous" testicular recrudescence. Recovery of gonadal function after prolonged exposure to intermediate DLs is thoug...

journal_title：Journal of biological rhythms

authors： Kauffman AS,Zucker I

更新日期：2002-08-01 00:00:00

abstract：:Rhodopsin 7 ( Rh7), a new invertebrate Rhodopsin gene, was discovered in the genome of Drosophila melanogaster in 2000, but its function has remained elusive. We generated an Rh7 null mutant ( Rh70) by P element-mediated mutagenesis and found that an absence of Rh7 had significant effects on fly activity patterns duri...

journal_title：Journal of biological rhythms

authors： Kistenpfennig C,Grebler R,Ogueta M,Hermann-Luibl C,Schlichting M,Stanewsky R,Senthilan PR,Helfrich-Förster C

更新日期：2017-10-01 00:00:00

abstract：:Groups of Syrian hamsters were exposed to LD cycles with twilight transitions and photoperiods simulating natural lighting conditions at the summer solstice (SS), equinox, and winter solstice (WS) at 41 degrees N and at the winter solstice at the Arctic Circle (WS 66 degrees N) but with daytime illuminance truncated a...

journal_title：Journal of biological rhythms

authors： Boulos Z,Macchi MM

更新日期：2005-04-01 00:00:00

abstract：:Male rose-ringed parakeets (Psittacula krameri) were transferred to a long photoperiod (LP; LD 16:8) or a short photoperiod (SP; LD 8:16) for 45 or 90 days on four dates corresponding to the beginnings of different reproductive phases in an annual testicular cycle, and testicular responsiveness was evaluated by compar...

journal_title：Journal of biological rhythms

authors： Maitra SK,Dey M

更新日期：1992-04-01 00:00:00

abstract：:The mammalian endogenous circadian clock, the suprachiasmatic nuclei, receives environmental inputs, namely the light-dark cycle, through photopigments located in the eye and from melanopsin-expressing retinal ganglion cells. The authors investigated the influence of light wavelength and intensity on the synchronizati...

journal_title：Journal of biological rhythms

authors： Perret M,Gomez D,Barbosa A,Aujard F,Théry M

更新日期：2010-06-01 00:00:00

abstract：:The human circadian timing system has previously been shown to free run with a period slightly longer than 24 h in subjects living in the laboratory under conditions of forced desynchrony. In forced desynchrony, subjects are shielded from bright light and periodic time cues and are required to live on a day length out...

journal_title：Journal of biological rhythms

authors： Kelly TL,Neri DF,Grill JT,Ryman D,Hunt PD,Dijk DJ,Shanahan TL,Czeisler CA

更新日期：1999-06-01 00:00:00

abstract：:The authors sought to investigate the role of phytochromes A and B (phyA and phyB) and cryptochromes 1 and 2 (cryl and cry2) in the synchronization of the leaf position rhythm in Arabidopsis thaliana. The seedlings were transferred from white light-dark cycles to free-running conditions with or without exposure to a l...

journal_title：Journal of biological rhythms

authors： Yanovsky MJ,Mazzella MA,Whitelam GC,Casal JJ

更新日期：2001-12-01 00:00:00

abstract：:DEC1 and DEC2-basic helix-loop-helix transcription factors-exhibit a circadian expression in the suprachiasmatic nucleus and other peripheral tissues and seem to play roles in regulating the mammalian circadian rhythm by suppressing the CLOCK/BMAL1-activated promoters of Per1, Dec1, and Dec2. The authors present data ...

journal_title：Journal of biological rhythms

authors： Noshiro M,Furukawa M,Honma S,Kawamoto T,Hamada T,Honma K,Kato Y

更新日期：2005-10-01 00:00:00

abstract：:The authors analyzed the upstream regulatory region of purF, a gene that is expressed in a minority phase that peaks at dawn (class 2 circadian phasing) in Synechococcus elongatus, to determine whether specific cis elements are responsible for this characteristic expression pattern. Fusions of various promoter-bearing...

journal_title：Journal of biological rhythms

authors： Min H,Liu Y,Johnson CH,Golden SS

更新日期：2004-04-01 00:00:00

abstract：:The mammalian SCN contains a biological clock that drives remarkably precise circadian rhythms in vivo and in vitro. Recent advances have revealed molecular and cellular mechanisms required for the generation of these daily rhythms and their synchronization between SCN neurons and to the environmental light cycle. Thi...

journal_title：Journal of biological rhythms

authors： Hastings MH,Herzog ED

更新日期：2004-10-01 00:00:00

abstract：:We have recently shown that molecular rhythms in the murine suprachiasmatic nucleus (SCN) are affected by repeated social defeat (SD) during the dark/active phase (social defeat dark [SDD]), while repeated SD during the light/inactive phase (social defeat light [SDL]) had no influence on PERIOD2::LUCIFERASE explant rh...

journal_title：Journal of biological rhythms

authors： Bartlang MS,Oster H,Helfrich-Förster C

更新日期：2015-06-01 00:00:00