Silencing of a gene encoding a protein component of the oxygen-evolving complex of photosystem II enhances virus replication in plants.

abstract：:A class of disulfide constrained peptides containing a core motif FPWG was identified from a screen of phage displayed library using the HCV RNA-dependent RNA polymerase (NS5B) as a bait. Surface plasmon resonance studies showed that three highly purified synthetic constrained peptides bound to immobilized NS5B with e...

journal_title：Virology

authors： Amin A,Zaccardi J,Mullen S,Olland S,Orlowski M,Feld B,Labonte P,Mak P

更新日期：2003-08-15 00:00:00

abstract：:The long terminal repeat (LTR) of mouse mammary tumor virus (MMTV) encodes a protein which functions as a superantigen. The BALB/cV strain differs from other exogenous MMTVs antigenically, biochemically, on the basis of restriction fragment analysis, and by the specificity of its superantigen for V beta 2+ T cells. In...

journal_title：Virology

authors： Kang JJ,Schwegel T,Knepper JE

更新日期：1993-09-01 00:00:00

abstract：:Cucumber seedlings infected with cucumber mosaic virus (CMV) contain a virus-induced RNA-dependent RNA polymerase (RNA replicase) in both soluble and particulate fractions of plant extracts; no such activity is found in uninfected plants. The extensive purification and characterization of the soluble RNA replicase has...

journal_title：Virology

authors： Gill DS,Kumarasamy R,Symons RH

更新日期：1981-08-01 00:00:00

abstract：:Multibranched peptides (SPCs) derived either from the fusion protein (gp41) sequence or from the cleavage sequence of the human immunodeficiency virus type 1 envelope were chemically synthesized and tested for their ability to inhibit both syncytium formation and HIV production in CD4+ cells. The gp41-derived SPCs had...

journal_title：Virology

authors： Sabatier JM,Mabrouk K,Moulard M,Rochat H,Van Rietschoten J,Fenouillet E

更新日期：1996-09-15 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV-68) replicates robustly in cell culture, providing a model for studying viral genome replication during de novo infection of tumor-associated herpesviruses. We have previously identified a 1.25-kb origin of lytic replication (oriLyt) for MHV-68. To further investigate the molecular mech...

journal_title：Virology

authors： Gong D,Qi J,Arumugaswami V,Sun R,Deng H

更新日期：2009-05-10 00:00:00

abstract：:Respiratory syncytial virus is a major cause of bronchiolitis in infants and pneumonia virus of mice (PVM) causes similar disease in mice. The impact of PVM infection in BALB/c and C57BL/6 neonates, and upon re-infection as elderly mice, was compared. As previously shown for adult mice, PVM caused more disease in BALB...

journal_title：Virology

authors： Shrivastava P,Atanley E,Sarkar I,Watkiss E,Gomis S,van Drunen Littel-van den Hurk S

更新日期：2015-11-01 00:00:00

abstract：:Assembly of the viral genome into virions is a critical process of the virus life cycle often defining the ability of the virus to move within the plant and to be transmitted horizontally to other plants. Closteroviridae virions are polar helical rods assembled primarily by a major coat protein, but with a related min...

journal_title：Virology

authors： Satyanarayana T,Gowda S,Mawassi M,Albiach-Martí MR,Ayllón MA,Robertson C,Garnsey SM,Dawson WO

更新日期：2000-12-05 00:00:00

abstract：:Two temperature-sensitive mutants of herpes simplex virus type 1 in complementation group 1-1 were analyzed to determine if the major DNA-binding protein they produced was thermolabile. Cells infected with these mutants were analyzed for deoxyribonucleoprotein complexes containing the DNA-binding protein. These comple...

journal_title：Virology

authors： Leinbach SS,Casto JF,Pickett TK

更新日期：1984-09-01 00:00:00

abstract：:The human parvovirus B19 causes aplastic crises in sickle cell anemia patients and the disease erythema infectiosum. So far, it has not been possible to grow B19 virus in cultured cells. Here we report the use of in vitro transcription in HeLa cell extracts and transient expression of cloned DNA transfected into HeLa ...

journal_title：Virology

authors： Doerig C,Beard P,Hirt B

更新日期：1987-04-01 00:00:00

abstract：:The mechanism of intracellular retention for the large surface protein (L) of duck hepatitis B virus (DHBV) was analyzed by examination of the transmembrane topologies and secretory properties of a collection of DHBV L mutants and compared with that of human hepatitis B virus (HBV) L. Our results demonstrate that, in ...

journal_title：Virology

authors： Gazina EV,Lin B,Gallina A,Milanesi G,Anderson DA

更新日期：1998-03-15 00:00:00

abstract：:West Nile virus is a mosquito-borne, neurotropic flavivirus that causes encephalitis in humans and animals. Since being introduced into the Western hemisphere in 1999, WNV has spread rapidly across North America, identifying this virus as an important emerging pathogen. In this study, we developed a DNA-launched infec...

journal_title：Virology

authors： Pierson TC,Diamond MS,Ahmed AA,Valentine LE,Davis CW,Samuel MA,Hanna SL,Puffer BA,Doms RW

更新日期：2005-03-30 00:00:00

abstract：:The expression of two small basic proteins (C and C') encoded by a second open reading frame of the New Jersey serotype of vesicular stomatitis virus (VSV) P gene was reported previously (Spiropoulou and Nichol, J. Virol., 67, 3103-3110, 1993). Here we found that the Indiana serotype virus also expressed C and C' prot...

journal_title：Virology

authors： Kretzschmar E,Peluso R,Schnell MJ,Whitt MA,Rose JK

更新日期：1996-02-15 00:00:00

abstract：:The protein p10 that forms the connector of phage phi 29, has been produced in Escherichia coli harboring a plasmid that carried the gene coding for this protein. The connector protein is assembled in a 13.4-S oligomer that has an apparent molecular weight of 460,000, suggesting that it is a dodecamer. The purified ol...

journal_title：Virology

authors： Carrascosa JL,Carazo JM,Ibañez C,Santisteban A

更新日期：1985-03-01 00:00:00

abstract：:The complete nucleotide sequence of the RSV cpts-248/404 live attenuated vaccine candidate was determined from cloned cDNA and was compared to that of the RSV A2/HEK7 wild-type, cold-passaged cp-RSV, and cpts-248 virus, which constitute the series of progenitor viruses. RSV cpts-248/404 is more attenuated and more tem...

journal_title：Virology

authors： Firestone CY,Whitehead SS,Collins PL,Murphy BR,Crowe JE Jr

更新日期：1996-11-15 00:00:00

abstract：:The mouse mammary tumor virus (MMTV) is a type B retrovirus that is unique from other retroviruses in having multiple "tissue specific" and "hormone inducible" promoters. This unique feature has lead to the increasing interest in studying the biology of MMTV replication with the ultimate goal of developing MMTV based ...

journal_title：Virology

authors： Rizvi TA,Ali J,Phillip PS,Ghazawi A,Jayanth P,Mustafa F

更新日期：2009-03-15 00:00:00

abstract：:Large numbers of VSV (LCMV) pseudotypes with the genomes of vesicular stomatitis virus (VSV) and the coat proteins of lymphocytic choriomeningitis virus (LCMV) were produced by infecting L cells first with LCMV and subsequently with VSV, the latter in the presence of tunicamycin. Separation by gradient centrifugation ...

journal_title：Virology

authors： Bruns M,Lehmann-Grube F

更新日期：1984-08-01 00:00:00

abstract：:The molecular mechanism(s) by which human immunodeficiency virus (HIV-1) injures a T-cell line was studied. A pathological role for viral env proteins, which are inserted into the plasma membrane, has been previously demonstrated for HIV as well as other retroviruses which are cytopathic. We therefore initiated studie...

journal_title：Virology

authors： Lynn WS,Tweedale A,Cloyd MW

更新日期：1988-03-01 00:00:00

abstract：:The v-erb B protein of avian erythroblastosis virus (AEV) possesses an associated protein kinase activity in vitro. Analysis of temperature-sensitive mutants, and nonconditional host range mutants of AEV demonstrated that there was no simple correlation between this autophosphorylation activity and the transformation ...

journal_title：Virology

authors： Hayman MJ,Kitchener G,Knight J,McMahon J,Watson R,Beug H

更新日期：1986-04-15 00:00:00

abstract：:The function of a substantial percentage of the putative protein-coding open reading frames (ORFs) in viral genomes is unknown. As their sequence is not similar to that of proteins of known function, the function of these ORFs cannot be assigned on the basis of sequence similarity. Methods complement or in combination...

journal_title：Virology

authors： Han LY,Cai CZ,Ji ZL,Chen YZ

更新日期：2005-01-05 00:00:00

abstract：:The envelope glycoprotein (Env) of Moloney murine leukemia virus (MoMuLV) is proteolytically processed and transported to the cell surface where it can be incorporated into budding virions. Cell surface Env is frequently detected using an indirect immunofluorescence assay and fluorescence-activated cell sorting (FACS)...

journal_title：Virology

authors： Yu H,Empig C,Xia J,Anderson WF

更新日期：1998-04-10 00:00:00

abstract：:Tissues from Australian brushtail possums (Trichosurus vulpecula) that had been experimentally infected with wobbly possum disease (WPD) virus (WPDV) were examined to elucidate pathogenesis of WPDV infection. Mononuclear inflammatory cell infiltrates were present in livers, kidneys, salivary glands and brains of WPD-a...

journal_title：Virology

authors： Giles J,Perrott M,Roe W,Shrestha K,Aberdein D,Morel P,Dunowska M

更新日期：2018-09-01 00:00:00

abstract：:Porcine epidemic diarrhea virus (PEDV) is a causative agent of porcine epidemic diarrhea (PED). PED, characterized by acute diarrhea, vomiting, dehydration, has caused serious economic losses in pig industry worldwide. Here, we demonstrate that activation of a disintergrin and metalloprotease 17 (ADAM17) induced the d...

journal_title：Virology

authors： Zhang J,Guo L,Yang L,Xu J,Zhang L,Feng L,Chen H,Wang Y

更新日期：2018-04-01 00:00:00

abstract：:Three proteins, reacting specifically with sera raised against synthetic peptides identical to C-terminal amino acid sequences in alfalfa mosaic virus (AIMV) proteins P1, P2, and P3 translated in vitro from the AIMV RNAs 1, 2, and 3, respectively, were for the first time observed in tobacco and cowpea protoplasts. Par...

journal_title：Virology

authors： van Pelt-Heerschap H,Verbeek H,Huisman MJ,Sue Loesch-Fries L,Van Vloten-Doting L

更新日期：1987-11-01 00:00:00

abstract：:African swine fever virus (ASFV) growth and plaque formation were inhibited by phosphonoacetic acid (PAA) concentrations of 200 micrograms/ml or more. One spontaneous mutant and two mutants isolated from mutagenized virus were resistant to PAA inhibition and showed practically normal viral DNA synthesis in the presenc...

journal_title：Virology

authors： Marques MI,Costa JV

更新日期：1995-12-01 00:00:00

abstract：:Human hepatitis B virus (HBV) envelopes contain three distinct glycoproteins called L, M, and S HBsAg. Each is posttranslationally modified to contain N-linked oligosaccharides. N-linked oligosaccharides, after attachment to a polypeptide backbone, are processed by enzymes within the endoplasmic reticulum (ER). There ...

journal_title：Virology

authors： Lu X,Mehta A,Dwek R,Butters T,Block T

更新日期：1995-11-10 00:00:00

abstract：:We have quantitated replication of the RNA genomes of vesicular stomatitis virus (VSV) and its defective interfering (DI) particles in a BHK21 cell-free system into which nucleocapsids were introduced in varying amounts and ratios, with or without addition of purified virus polymerase components. The quantitative tran...

journal_title：Virology

authors： Giachetti C,Holland JJ

更新日期：1989-05-01 00:00:00

abstract：:Insertion of nucleotide sequences encoding "tags" that can be expressed in specific viral proteins during an infection is a useful strategy for purifying viral proteins and their functional complexes from infected cells and/or for visualizing the dynamics of their subcellular location over time. To identify regions in...

journal_title：Virology

authors： Teterina NL,Lauber C,Jensen KS,Levenson EA,Gorbalenya AE,Ehrenfeld E

更新日期：2011-01-05 00:00:00

abstract：:cDNA clones of the St. Louis encephalitis (SLE) virus genome have been obtained and the nucleotide sequence of 4.7 kb corresponding to the 5' terminal half of the genome determined. The genome contains a 5' noncoding region of 98 nucleotides followed by a single continuous open reading frame that encodes three structu...

journal_title：Virology

authors： Trent DW,Kinney RM,Johnson BJ,Vorndam AV,Grant JA,Deubel V,Rice CM,Hahn C

更新日期：1987-02-01 00:00:00

abstract：:Three SV40 escape mutants were identified by selection in the presence of monoclonal antibodies with neutralizing activity. The VP1 amino acid alterations in these mutants were: (1) K73-->E (in loop BC); (2) D77-->E (in loop BC); (3) K171-->R (in loop EF); and (4) Q175-->H (in loop EF). These residues are clustered in...

journal_title：Virology

authors： Murata H,Teferedegne B,Sheng L,Lewis AM Jr,Peden K

更新日期：2008-11-10 00:00:00

abstract：:Fowlpox virus (FPV), type species of the Avipoxvirus genus, causes a slow-spreading pox disease of chickens. Following infection of mammalian cells there is no evidence of productive replication of FPV although cytopathic effects are induced and FPV recombinants have been shown to express foreign genes from vaccinia v...

journal_title：Virology

authors： Somogyi P,Frazier J,Skinner MA

更新日期：1993-11-01 00:00:00