当前位置： SCI文献检索 > SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY期刊下所有文献 > Severe jaundice in Sweden in the new millennium: causes, investigations, treatment and prognosis.

Severe jaundice in Sweden in the new millennium: causes, investigations, treatment and prognosis.

Abstract：

BACKGROUND:The aims of the study were to assess the causes of jaundice in Gothenburg, Sweden, to study the types of investigations applied in cholestatic and hepatocellular types of jaundice and treatment and to evaluate the prognosis of these patients up to a year from the diagnosis. METHODS:Over a 3-month period, all adult patients with bilirubin > 100 micromol/l were identified by the clinical chemistry laboratory serving all three hospitals in Gothenburg. Relevant clinical information was obtained from medical records. Follow-up was performed 9-12 months later. RESULTS:A total of 173 patients were identified; 40% were under surgical care while 38% were in the care of internists. The most common cause of jaundice was malignancy in 58 patients, liver metastases in 20, cholangiocarcinoma in 16, pancreatic cancer in 13, cancer of papilla Vateri in 2 and primary liver cancer in 7. Alcoholic liver disease was the second most common cause, found in 29 patients, followed by bile duct stones (28 patients). Only 3% had viral hepatitis. Ultrasound and/or CT were performed in 95% of those with cholestasis and ultrasound had been performed in 75% of those with hepatocellular type and CT in almost 50%. Thirty-two patients were operated on, 27 patients were treated endoscopically and 17 patients required liver transplantation. Total mortality was 51% and in malignancy 82%. CONCLUSION:Malignancy and alcoholic liver disease are the most common causes of severe jaundice, whereas viral hepatitis is a rare cause. Many patients are under surgical care, probably due to historical reasons as surgery is rarely indicated.

journal_name

Scand J Gastroenterol

journal_title

Scandinavian journal of gastroenterology

authors

Björnsson E,Ismael S,Nejdet S,Kilander A

doi

10.1080/00365520310000492

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

86-94

issue

1

eissn

0036-5521

issn

1502-7708

journal_volume

38

pub_type

杂志文章

相关文献

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY文献大全
  • Bioavailability of prednisolone in patients with intestinal malabsorption: the importance of measuring serum protein-binding.

    abstract：:The effect of intestinal malabsorption on the oral bioavailability of prednisolone has been studied in six patients with celiac disease and in six patients with malabsorption of various etiologies, five of whom had undergone gut resections. The serum protein-binding of prednisolone was measured in five patients with c...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528309181635

    authors： Bergrem H,Opedal I

    更新日期：1983-05-01 00:00:00

  • The multi-crossover model for classifying patients as responders to a given treatment.

    abstract：:The strength and the validity of the multi-crossover model (MCO model) were investigated to optimalize the procedure for correctly classifying individual responders to a given therapy. One hundred and fifteen patients with non-ulcer dyspepsia from seven Norwegian hospitals were included in a 6-week double-blind MCO-de...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.3109/00365529108998597

    authors： Larsen S,Farup P,Flaten O,Osnes M

    更新日期：1991-07-01 00:00:00

  • Probable role of both sulfhydryls and prostaglandins in gastric mucosal protection induced by S-adenosylmethionine.

    abstract：:The role of both sulfhydryl groups and endogenous prostaglandins in the protective effect of S-adenosylmethionine against ethanol-induced gastric mucosal damage was studied in rats. Drugs were administered subcutaneously or intragastrically to fasted rats 30 or 60 min before 100% ethanol (1 ml/rat), and mucosal lesion...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528909089244

    authors： Gutiérrez-Cabano CA

    更新日期：1989-10-01 00:00:00

  • Cardiovascular risk factors in obese patients treated with jejunoileal bypass operation: a 25-year follow-up study.

    abstract：OBJECTIVE:Jejunoileal (JI) bypass was a widely performed surgical procedure for morbid obesity in the 1970s. The purpose of this study was to assess cardiovascular risk factors and mortality in patients 25 years or more after this operation. MATERIAL AND METHODS:All (n = 36) patients operated on for obesity with JI by...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520410009393

    authors： Våge V,Berstad A,Solhaug JH,Viste A

    更新日期：2005-01-01 00:00:00

  • Bone mineral after partial gastrectomy II.

    abstract：:The bone mineral content estimated by gamma ray attenuation method, serum calcium, phosphorus, alkaline phosphatase, and protein was examined in three types of patients with peptic ulcer. The bone mineral content in ulcer patients before surgery did not differ from that of the control series. In patients subjected to ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Aukee S,Alhava EM,Karjalainen P

    更新日期：1975-01-01 00:00:00

  • Multicenter prospective study for clinical and endoscopic efficacies of leukocytapheresis therapy in patients with ulcerative colitis.

    abstract：OBJECTIVE:This study aimed to assess the efficacy and tolerability of leukocytapheresis (LCAP) and to investigate predictive factors for mucosal healing and a sustained clinical response in steroid-free and steroid-refractory patients with ulcerative colitis (UC). MATERIAL AND METHODS:Thirty-one steroid-free or steroi...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,多中心研究

    doi：10.3109/00365521.2012.763175

    authors： Okuyama Y,Andoh A,Nishishita M,Fukunaga K,Kamikozuru K,Yokoyama Y,Ueno Y,Tanaka S,Kuge H,Yoshikawa S,Sugahara A,Anami E,Munetomo Y,Watanabe C,Fujiyama Y,Matsumoto T

    更新日期：2013-04-01 00:00:00

  • The effect of body position on postprandial perceptions, gastric emptying, and intragastric meal distribution: an ultrasonographic study in reclining healthy subjects.

    abstract：OBJECTIVE:Postprandial dyspepsia is common and may be associated with abnormal intragastric distribution of food. We aimed to determine the effect of body position on gastric emptying, meal distribution, and postprandial perceptions in healthy subjects. MATERIAL AND METHODS:Eight adolescents (4 females and 4 males age...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365521.2014.990506

    authors： Valeur J,Berstad A,Hausken T

    更新日期：2015-02-01 00:00:00

  • Helicobacter pylori-associated gastritis and dyspepsia. The influence on migrating motor complexes.

    abstract：:Twenty-five patients with dyspepsia were included. In 19 patients with a median age of 48 (range, 20-72) years endoscopy and histologic examination of biopsy specimens from the antrum and corpus of the stomach showed Helicobacter pylori-positive gastritis as the only pathologic finding. In six patients with a median a...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529409090451

    authors： Qvist N,Rasmussen L,Axelsson CK

    更新日期：1994-02-01 00:00:00

  • Preoperative oral polymeric diet enriched with transforming growth factor-beta 2 (Modulen) could decrease postoperative morbidity after surgery for complicated ileocolonic Crohn's disease.

    abstract：OBJECTIVE:Exclusive polymeric diet enriched with transforming growth factor-beta 2 (ANS-TGF-β2) has been used for remission induction and maintenance in pediatric Crohn's disease (CD). Its use in the preoperative setting has never been evaluated. The aim of this study was to evaluate preoperative ANS-TGF-β2 to decrease...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365521.2016.1221994

    authors： Beaupel N,Brouquet A,Abdalla S,Carbonnel F,Penna C,Benoist S

    更新日期：2017-01-01 00:00:00

  • Serum bile acid concentration after a test meal.

    abstract：:Total serum bile acid concentrations were studied by an enzymatic-fluorimetric method employing a highly purified 3 alpha-hydroxysteroid dehydrogenase. In 28 control subjects mean total serum bile acid concentration was 2.5 mumoles/1 (S.D. 1.4). In 6 healthy subjects a significant postprandial increase in total serum ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Fausa O

    更新日期：1976-01-01 00:00:00

  • Heparin effect on thromboelastography after transjugular intrahepatic portosystemic shunt procedure.

    abstract：OBJECTIVE:In patients with cirrhosis and bacterial infection there is impaired coagulation and a heparin effect on thromboelastography (TEG). Our aim was to assess the presence of a heparin effect on heparinase I-modified TEG in patients before and after transjugular intrahepatic portosystemic shunt (TIPS). Our hypothe...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365520903342174

    authors： Thalheimer U,Triantos C,Samonakis D,Patch D,Burroughs AK

    更新日期：2009-01-01 00:00:00

  • The CCK-2 receptor is located on the ECL cell, but not on the parietal cell.

    abstract：BACKGROUND:The interrelationship between histamine and gastrin in the physiological regulation of gastric acid secretion is still a matter of dispute. CCK-2 receptors are located on enterochromaffin-like (ECL) cells in corpus mucosa and gastrin stimulates acid production by releasing histamine from the ECL cells, which...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520152584734

    authors： Bakke I,Qvigstad G,Sandvik AK,Waldum HL

    更新日期：2001-11-01 00:00:00

  • Treatment of postoperative paralytic ileus with cisapride.

    abstract：:The effect of cisapride on postoperative colonic motility was studied in 40 patients undergoing cholecystectomy under randomized, double-blind conditions. The patients received 10 mg of cisapride or placebo by intravenous injection starting on the day of surgery and repeated every 12 h until the 3rd postoperative day....

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.3109/00365529108998569

    authors： Tollesson PO,Cassuto J,Rimbäck G,Faxén A,Bergman L,Mattsson E

    更新日期：1991-05-01 00:00:00

  • Course of choledochal cysts according to the type of treatment.

    abstract：OBJECTIVE:To compare natural course and treatment results of various types of choledochal cysts. MATERIAL AND METHODS:Complication rate in treated (T) and natural course in not treated (NT) patients with choledochal cysts were compared. The level of bilioenteric anastomosis after cyst resection was categorized and the...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365521003675054

    authors： Kim JW,Moon SH,Park DH,Lee SS,Seo DW,Kim MH,Lee SK

    更新日期：2010-06-01 00:00:00

  • Hydrogen peroxide stimulates phospholipase A2-mediated arachidonic acid release in cultured intestinal epithelial cells (INT 407).

    abstract：:The mechanisms by which hydrogen peroxide and, for comparison, 4-beta-phorbol-12-myristate-13-acetate (PMA) stimulate release of radiolabeled arachidonic acid (14C-AA) in cultured intestinal epithelial cells (INT 407) were investigated. Both hydrogen peroxide and PMA caused a rapid (3 min) and dose-related intracellul...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529109025037

    authors： Gustafson C,Lindahl M,Tagesson C

    更新日期：1991-03-01 00:00:00

  • Faecal fat and faecal weight: reproducibility and diagnostic efficiency of various regimens.

    abstract：:The reproducibility of measuring 3-day faecal fat and weight in outpatients, in inpatients served a fixed diet, and in intake-excretion studies was estimated from 64 duplicate measurements. Qualitatively, no significant difference between the results of the three regimens was found. Quantitatively, however, the more c...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Pedersen NT,Halgreen H

    更新日期：1984-05-01 00:00:00

  • Unkilned and large amounts of oats in the coeliac disease diet: a randomized, controlled study.

    abstract：OBJECTIVE:There is evidence for the long-term safety of oats as part of a gluten-free diet in coeliac disease (CD). Oats is generally processed by kilning, which theoretically may change its antigenic properties and be the reason that it is tolerated by patients with CD. The aim of this study was to investigate the sui...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,随机对照试验

    doi：10.1080/00365520802014858

    authors： Kemppainen TA,Heikkinen MT,Ristikankare MK,Kosma VM,Sontag-Strohm TS,Brinck O,Salovaara HO,Julkunen RJ

    更新日期：2008-01-01 00:00:00

  • The changing histological pattern of gastric polyps in an ethnically heterogeneous population.

    abstract：BACKGROUND AND AIM:Variation in the prevalence of various types of gastric polyps worldwide may reflect different etiologies. Here, the authors report the dynamic changes in histological distribution of gastric polyps over time and by ethnicity for individuals who underwent gastroscopies between 1994 and 2009 at two ho...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365521.2012.682091

    authors： Peretz A,Fuchs T,Livovsky DM,Turvall E,Pappo O,Ackerman Z

    更新日期：2012-09-01 00:00:00

  • Crohn's disease of the distal large bowel.

    abstract：:This study describes the clinical features and management of 80 patients with Crohn's disease affecting initially only the rectum with or without involvement of the sigmoid colon. Most patients were treated medically, and the various measures used are considered; the cumulative probability of completing five years und...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Ritchie JK,Lennard-Jones JE

    更新日期：1976-01-01 00:00:00

  • Relevance of abdominal gas analysis and transit study after colorectal cancer surgery.

    abstract：BACKGROUND:Colon gas volume analysis using abdominal radiographs is an objective and reproducible method for evaluating functional bowel disorders. The aim of this study was to clarify the relevance of colon gas distribution and transit time in rectosigmoid cancer patients after surgery. METHODS:Segmental colon gas vo...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365520310000898

    authors： Seike K,Koda K,Oda K,Kondo E,Ishizuka M,Miyazaki M

    更新日期：2003-04-01 00:00:00

  • Significance of the thickness of the anal sphincters with age and its relevance in faecal incontinence.

    abstract：BACKGROUND:Ultrasonographic studies in healthy volunteers showed that the external anal sphincter (EAS) and internal anal sphincter (IAS) thicknesses were inversely related at rest. The functional importance of the two sphincters in continence control was demonstrated in the relationship between the sum of the thicknes...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365529409092498

    authors： Papachrysostomou M,Pye SD,Wild SR,Smith AN

    更新日期：1994-08-01 00:00:00

  • Diagnosis of Helicobacter pylori infection in patients with atrophic gastritis: comparison of histology, 13C-urea breath test, and serology.

    abstract：BACKGROUND:Atrophic gastritis, a risk factor for gastric cancer, is a late consequence of Helicobacter pylori infection in approximately one-third of the infected patients. It has been suggested that gastric cancer would develop less frequently if H. pylori were eradicated. However, the prevalence of H. pylori infectio...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/003655200750024290

    authors： Kokkola A,Rautelin H,Puolakkainen P,Sipponen P,Färkkilä M,Haapiainen R,Kosunen TU

    更新日期：2000-02-01 00:00:00

  • Selected bacterial antibodies in Crohn's disease and ulcerative colitis.

    abstract：:Agglutinins to four strains of anaerobic gram-positive coccoid rods (species of Eubacterium, Peptostreptococcus and Coprococcus) were found in significantly higher frequency in Crohn's disease (CD) than in ulcerative colitis (UC) and in other diseased control subjects and were virtually absent in apparently healthy su...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365528309181586

    authors： Auer IO,Röder A,Wensinck F,van de Merwe JP,Schmidt H

    更新日期：1983-03-01 00:00:00

  • Mortality associated with gastroesophageal reflux disease and its non-malignant complications: a systematic review.

    abstract：OBJECTIVE:The mortality associated with malignant complications of gastroesophageal reflux disease (GERD) is well recognized. The aim of this systematic review was to assess the less well-examined mortality associated with GERD and its non-malignant complications, including esophageal erosions, ulcers, bleeding, perfor...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章,评审

    doi：10.1080/00365520701785475

    authors： Becher A,El-Serag HB

    更新日期：2008-01-01 00:00:00

  • Extended lamivudine consolidation therapy in hepatitis B e antigen-positive chronic hepatitis B patients improves sustained hepatitis B e antigen seroconversion.

    abstract：OBJECTIVES:Longer lamivudine (LAM) consolidation therapy after hepatitis B e antigen (HBeAg) seroconversion has been demonstrated to reduce the cumulative relapse rate. However, the optimal interval of LAM consolidation therapy remains controversial. We evaluated the post-treatment durability of LAM-induced HBeAg seroc...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.3109/00365520903394550

    authors： Kuo YH,Chen CH,Wang JH,Hung CH,Tseng PL,Lu SN,Changchien CS,Lee CM

    更新日期：2010-01-01 00:00:00

  • Is the time of dosing of a potent long-acting H2-receptor antagonist critical? Twenty-four-hour pH measurements with SKF-94482.

    abstract：:Reduction of daytime as well as nighttime acidity is important in the healing of duodenal ulceration and reflux oesophagitis. The importance of the time of dosing of potent, long-acting H2 blockers for optimal suppression of intragastric acidity is unknown. The efficacy of different oral dosage regimens of SKF-94482, ...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.3109/00365529108998573

    authors： Wilder-Smith CH,Merki HS

    更新日期：1991-05-01 00:00:00

  • Low incidence of Helicobacter pylori infection in patients with duodenal ulcer and chronic liver disease.

    abstract：BACKGROUND:Duodenal ulcer (DU) is a common problem in patients with chronic liver disease (CLD) and with inadequate response to H2 receptor antagonists. Omeprazole might be more effective. In DU-CLD patients, Helicobacter pylori prevalence is low. Nitric oxide is increased in gastric mucosa in cirrhosis. Oxygen-free ra...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章

    doi：10.1080/003655201750153250

    authors： Shahin WA,Abdel-Baset EZ,Nassar AK,Atta MM,Kabil SM,Murray JA

    更新日期：2001-05-01 00:00:00

  • Ulcerative colitis, seronegative spondyloarthropathies and allergic diseases: the search for a link.

    abstract：BACKGROUND:Allergic diseases and seronegative spondyloarthropathies are frequently observed in ulcerative colitis (UC). In this report we have investigated possible relationships between IgE-mediated allergic disease (AD), allergic contact dermatitis (ACD) and seronegative spondyloarthropathy (SpA) in UC patients at di...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/003655202760373362

    authors： D'Arienzo A,Manguso F,Scarpa R,Astarita C,D'Armiento FP,Bennato R,Gargano D,Sanges M,Mazzacca G

    更新日期：2002-10-01 00:00:00

  • A pragmatic trial of cimetidine in duodenal ulcer patients.

    abstract：:Fifty-eight outpatients with a clinical and radiological diagnosis of duodenal ulcer completed a double-blind randomized trial of the effect of cimetidine on ulcer symptoms. Patients normally treated in general practice were included in the trial. The patients in the treatment group received cimetidine 1 g daily and t...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.3109/00365527709181342

    authors： Gudmand-Höyer E,Frost F,Jensen KB,Krag E,Rask-Madsen J,Rahbek I,Rune S,Wulff HR

    更新日期：1977-01-01 00:00:00

  • The role of mitochondrial folate enzyme MTHFD1L in esophageal squamous cell carcinoma.

    abstract：OBJECTIVE:The lack of novel therapeutic targets poses the major challenge to prolong survival and improve the quality of life for esophageal squamous cell carcinoma (ESCC). Methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) plays critical roles in folate cycle maintenance. However, little information is available...

    journal_title：Scandinavian journal of gastroenterology

    pub_type： 杂志文章

    doi：10.1080/00365521.2017.1407440

    authors： Yang YS,Yuan Y,Hu WP,Shang QX,Chen LQ

    更新日期：2018-05-01 00:00:00