A pragmatic trial of cimetidine in duodenal ulcer patients.

Abstract:

:Fifty-eight outpatients with a clinical and radiological diagnosis of duodenal ulcer completed a double-blind randomized trial of the effect of cimetidine on ulcer symptoms. Patients normally treated in general practice were included in the trial. The patients in the treatment group received cimetidine 1 g daily and the controls received inactive tablets. The treatment period was four weeks. During the last nine days 18 (60%) of 30 cimetidine-treated patients were symptom-free against 5 (18%) of 28 controls (P less than 0.005). The antacid consumption, the number of days with pain and the number of hours with pain also differed significantly in the two groups. Apart from a transient rash in one patient no important clinical side-effects were noted. The serum creatinine rose slightly in the cimetidine-treated patients.

journal_name

Scand J Gastroenterol

authors

Gudmand-Höyer E,Frost F,Jensen KB,Krag E,Rask-Madsen J,Rahbek I,Rune S,Wulff HR

doi

10.3109/00365527709181342

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

611-3

issue

5

eissn

0036-5521

issn

1502-7708

journal_volume

12

pub_type

临床试验,杂志文章,随机对照试验
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    authors: Tielemans Y,Chen D,Sundler F,Håkanson R,Willems G

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Naesdal J,Bodemar G,Walan A

    更新日期:1984-10-01 00:00:00

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    pub_type: 杂志文章

    doi:10.3109/00365529109003961

    authors: Mårdh S,Ma JY,Song YH,Aly A,Henriksson K

    更新日期:1991-10-01 00:00:00

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    journal_title:Scandinavian journal of gastroenterology

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    更新日期:2016-01-01 00:00:00

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    pub_type: 杂志文章,评审

    doi:10.1080/003655200750056565

    authors: Giercksky KE,Haglund U,Rask-Madsen J

    更新日期:2000-11-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1080/003655200750024038

    authors: de Bree E,Tsiftsis DD,Santos RM,Lavelle SM,Cuervas-Mons V,Gauthier A,Gips C,Malchow-Moeller A,Molino G,Rohr G,Theodossi A,Tsantoulas D

    更新日期:2000-04-01 00:00:00

  • Development and validation of a theoretical test in non-anaesthesiologist-administered propofol sedation for gastrointestinal endoscopy.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

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    更新日期:2016-07-01 00:00:00

  • Responses of anal constipation to biofeedback treatment.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410009348

    authors: Fernández-Fraga X,Azpiroz F,Casaus M,Aparici A,Malagelada JR

    更新日期:2005-01-01 00:00:00

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.654405

    authors: Li P,Sun P,Yang W,Zhang X

    更新日期:2012-04-01 00:00:00

  • Hereditary non-polyposis colorectal cancer: clinical features and survival. Results from the Danish HNPCC register.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529709025102

    authors: Myrhøj T,Bisgaard ML,Bernstein I,Svendsen LB,Søndergaard JO,Bülow S

    更新日期:1997-06-01 00:00:00

  • Enteroendocrine, Musashi 1 and neurogenin 3 cells in the large intestine of Thai and Norwegian patients with irritable bowel syndrome.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

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    authors: El-Salhy M,Patcharatrakul T,Hatlebakk JG,Hausken T,Gilja OH,Gonlachanvit S

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  • Disease activity and serum proteins in ulcerative colitis. Immunochemical quantitation.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Marner IL,Friborg S,Simonsen E

    更新日期:1975-01-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/00365529850166824

    authors: Hveem K,Svebak S,Hausken T,Berstad A

    更新日期:1998-02-01 00:00:00

  • Availability of energy substrates during liver regeneration in malnourished rats.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529108998607

    authors: Skullman S,Ihse I,Larsson J

    更新日期:1991-11-01 00:00:00

  • A novel one-hour 13C-sorbitol breath test versus the H2-sorbitol breath test for assessment of coeliac disease.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520902846233

    authors: Tveito K,Hetta AK,Askedal M,Brunborg C,Sandvik L,Løberg EM,Skar V

    更新日期:2009-01-01 00:00:00

  • Effects of treatment compliance and overnight gastric secretion on outcome of maintenance therapy of duodenal ulcer with ranitidine.

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    pub_type: 杂志文章

    doi:10.3109/00365528309181583

    authors: Boyd EJ,Wilson JA,Wormsley KG

    更新日期:1983-03-01 00:00:00

  • Muscarinic M2 stimulation releases histamine in the totally isolated, vascularly perfused rat stomach.

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    pub_type: 杂志文章

    doi:10.3109/00365528809090168

    authors: Sandvik AK,Kleveland PM,Waldum HL

    更新日期:1988-11-01 00:00:00

  • Fructose malabsorption is associated with decreased plasma tryptophan.

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    pub_type: 临床试验,杂志文章

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    pub_type: 临床试验,杂志文章

    doi:10.1080/00365529850171602

    authors: Tanum L,Bråtveit-Johansen K,Malt UF

    更新日期:1998-07-01 00:00:00

  • Duodenal ulcer treated with omeprazole: healing and relapse rates. Does treatment duration influence subsequent remission?

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528909089263

    authors: Farup PG,Rosseland AR,Halvorsen L,Andersen OK,Bernklev T

    更新日期:1989-11-01 00:00:00

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    pub_type: 杂志文章,多中心研究,随机对照试验

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  • Effect of elimination of acid reflux on epithelial cell proliferative activity of Barrett esophagus.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

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  • Radiofrequency ablation versus resection for the treatment of early stage hepatocellular carcinoma: a multicenter Australian study.

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    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Skude G

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    doi:

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    doi:

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