Occurrence of autoantibodies against intrinsic factor, H,K-ATPase, and pepsinogen in atrophic gastritis and rheumatoid arthritis.

Abstract:

:The occurrence of autoantibodies against intrinsic factor, H,K-ATPase, and pepsinogen was analysed by means of enzyme-linked immunosorbent assay in three groups of sera. Group 1 comprised sera from 14 rheumatoid arthritis patients with normal acid secretion; group 2, sera from 18 rheumatoid arthritis patients with reduced acid secretion; and group 3, sera from 11 patients with pernicious anaemia or achylia. Groups 1 and 2 were rheumatoid factor-positive, and group 3 was negative. Intrinsic factor autoantibodies were low in groups 1 and 2. In group 3, 9 of the 11 sera (82%) scored positive. The highest titres of H,K-ATPase and pepsinogen autoantibodies were found in groups 2 and 3. Only one serum in group 1 scored positive against H,K-ATPase, and two against pepsinogen, whereas corresponding values were 11 (61%) and 7 (39%) in group 2, and 10 (91%) and 6 (55%) in group 3. Autoantibodies against H,K-ATPase from a pool of patient sera recognized both the alpha- and beta-subunits of the enzyme. The present results support the hypothesis of an autoimmune disease overlap between non-organ-specific rheumatoid arthritis and organ-specific pernicious anaemia.

journal_name

Scand J Gastroenterol

authors

Mårdh S,Ma JY,Song YH,Aly A,Henriksson K

doi

10.3109/00365529109003961

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

1089-96

issue

10

eissn

0036-5521

issn

1502-7708

journal_volume

26

pub_type

杂志文章
  • Primary adenocarcinoma of the duodenum with choledochoduodenal fistula.

    abstract:BACKGROUND:Primary adenocarcinoma of the duodenum is an uncommon clinical entity. It has been associated with a dismal prognosis because it is rare and produces no distinctive symptoms until late in its course. CASE SUMMARY:A 68-year-old man presented with a 6-month history of epigastralgia, anorexia, and progressive ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529409094865

    authors: Tsai CJ

    更新日期:1994-10-01 00:00:00

  • Oral cromolyn sodium in comparison with elimination diet in the irritable bowel syndrome, diarrheic type. Multicenter study of 428 patients.

    abstract:BACKGROUND:In a significant number of patients affected by the irritable bowel syndrome, an adverse reaction to food is proposed to be a causative factor. A diet that eliminates the offending foods is the obvious treatment for such adverse reactions. Compliance with a dietetic regimen is often poor and sometimes not co...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.3109/00365529509089786

    authors: Stefanini GF,Saggioro A,Alvisi V,Angelini G,Capurso L,di Lorenzo G,Dobrilla G,Dodero M,Galimberti M,Gasbarrini G

    更新日期:1995-06-01 00:00:00

  • Development and feasibility of a telemonitoring tool with full integration in the electronic medical record: a proof of concept study for patients with inflammatory bowel disease in remission on biological therapy.

    abstract::Objectives: Telemonitoring can be implemented to enhance disease monitoring and ultimately reduce the number of outpatient visits and associated costs. We developed an in house IBD mobile app and established a proof of concept study to demonstrate the effectiveness and accuracy of the telemonitoring tool for monitorin...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1735506

    authors: Coenen S,Nijns E,Weyts E,Geens P,Van den Bosch B,Vermeire S,Ferrante M,Vanhaecht K,Van Assche G

    更新日期:2020-03-01 00:00:00

  • Effect of hepatic stimulator substance administration on tissue regeneration due to thioacetamide-induced liver injury in rats.

    abstract:BACKGROUND:Hepatic stimulator substance (HSS) is a known hepatic growth factor that appears to be organ-specific but species-nonspecific. In the present study we investigated the effect of HSS administration in a rat model of liver injury and regeneration induced by thioacetamide (TAA) injection. METHODS:TAA (300 mg/k...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365529850171954

    authors: Theocharis SE,Margeli AP,Agapitos EV,Mykoniatis MG,Kittas CN,Davaris PS

    更新日期:1998-06-01 00:00:00

  • Gastric parietal, chief, and G-cell densities in chronic renal failure.

    abstract::We calculated morphometrically the amount of antral gastrin-producing (G) cells and body parietal and chief cells in gastric biopsy specimens from 30 undialysed patients with chronic renal failure (CRF) and from sex- and age-matched controls. The CRF patients had raised fasting serum gastrin levels, whereas these were...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529108998586

    authors: Paronen I,Ala-Kaila K,Rantala I,Kainulainen H,Karvonen AL

    更新日期:1991-07-01 00:00:00

  • The use of a short-lived radionuclide in the investigation of acute bleeding in the upper gastrointestinal tract.

    abstract::A method is described for the detection and monitoring of bleeding in the upper gastrointestinal tract. A short-lived radionuclide (113In-m) is used. Acute bleeding in the upper gastrointestinal tract in patients without signs of shock and preshock usually stopped within a short time after onset. ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Pettersson C,Forssman O,Hollender A,Mulder JL

    更新日期:1975-01-01 00:00:00

  • Endogenous heparin-like activity detected by anti-Xa assay in infected cirrhotic and non-cirrhotic patients.

    abstract:BACKGROUND:Bacterial infections have been proposed as a trigger for portal hypertensive bleeding in cirrhotic patients. Endogenous low molecular weight heparinoids have been previously detected in vitro by heparinase-modified thromboelastography, but it is not known what type of heparinoids they are. The aim of this st...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410004433

    authors: Zambruni A,Thalheimer U,Coppell J,Riddell A,Mancuso A,Leandro G,Perry D,Burroughs AK

    更新日期:2004-09-01 00:00:00

  • Propofol combined with traditional sedative agents versus propofol- alone sedation for gastrointestinal endoscopy: a meta-analysis.

    abstract:OBJECTIVE:To assess the efficacy and safety of sedation of propofol combined with traditional sedative agents (PTSA) for gastrointestinal endoscopy, we conducted a meta-analysis of randomized controlled trials (RCTs) comparing PTSA with propofol-alone sedation. MATERIAL AND METHODS:RCTs comparing the effects of PTSA a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3109/00365521.2012.737360

    authors: Wang D,Wang S,Chen J,Xu Y,Chen C,Long A,Zhu Z,Liu J,Deng D,Chen J,Tang D,Wang L

    更新日期:2013-01-01 00:00:00

  • Human galanin modulates human colonic motility in vitro. Characterization of structural requirements.

    abstract:BACKGROUND:Human galanin (hGal) is a 30-residue non-amidated gut-brain peptide that shows considerable sequence divergence compared with galanin (Gal) forms of other species. Conflicting results have been reported with regard to the structural requirements for its modulatory action on gut motility. METHODS:We investig...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529609006763

    authors: Katsoulis S,Clemens A,Morys-Wortmann C,Schwörer H,Schaube H,Klomp HJ,Fölsch UR,Schmidt WE

    更新日期:1996-05-01 00:00:00

  • Uroguanylin inhibits proliferation of pancreatic cancer cells.

    abstract:OBJECTIVE:The peptide hormones guanylin and uroguanylin and their receptor, guanylate cyclase C (GC-C), are expressed in pancreatic duct cells. In colon cancer, guanylin peptides are shown to exert strong anti-tumor activity through the GC-C pathway. The objective of this study was to analyze the role of guanylin and u...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701746378

    authors: Kloeters O,Friess H,Giese N,Buechler MW,Cetin Y,Kulaksiz H

    更新日期:2008-01-01 00:00:00

  • Serum isoamylase activities in cystic fibrosis patients, determined by an inhibitory assay.

    abstract::Serum isoamylase activities were determined in patients with either cystic fibrosis (CF) or celiac disease and in age-matched healthy children by means of an inhibitory assay suitable for routine application. The percentage pancreatic isoamylase (PIA) activity was significantly decreased in CF patients when compared w...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528608996399

    authors: Maillie AJ,Vaccaro MI,Calvo EL,Ruiz JA,Emiliani R,Pivetta OH

    更新日期:1986-10-01 00:00:00

  • Differences in the clinical course of 516 Japanese patients with upper gastrointestinal bleeding between weekday and weekend admissions.

    abstract:BACKGROUND AND AIMS:Patients suspected of having upper gastrointestinal bleeding (UGIB) admitted during the weekend tend to have a poor outcome in western countries. However, no Japanese studies have been reported on this matter. We aimed to evaluate differences in the clinical course of patients with UGIB between week...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1377762

    authors: Fujita M,Manabe N,Murao T,Osawa M,Hirai S,Fukushima S,Shogen Y,Nakato R,Ishii M,Matsumoto H,Hata J,Shiotani A

    更新日期:2017-12-01 00:00:00

  • Liquid and solid gastric emptying in adults treated for Hirschsprung's disease during early childhood.

    abstract:OBJECTIVE:Dysmotility of the upper gastrointestinal tract has been reported in children with Hirschsprung's disease. In the present study, gastric emptying was studied in adult patients with Hirschsprung's disease to elucidate whether there is a persisting involvement of the upper gastrointestinal tract in this group o...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520600842211

    authors: Medhus AW,Bjørnland K,Emblem R,Husebye E

    更新日期:2007-01-01 00:00:00

  • Effect of vasopressin on canine gastric mucosal circulation.

    abstract::Continuous intravenous infusion of small doses of vasopressin (0.05 microgram/kg/h) in anaesthetized dogs was effective in reducing gastric mucosal flow, whereas moderate doses (0.2 micrograms/kg/h) induced a substantial flow reduction. Larger doses of vasopressin (2-4 micrograms/kg/h) precipitated massive gastric flo...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528209181103

    authors: Semb BK,Steen S,Solhaug JH

    更新日期:1982-10-01 00:00:00

  • Acoustic radiation force impulse elastography and serum fibrosis markers in chronic hepatitis C.

    abstract:OBJECTIVE:Liver biopsy (LB) remains the gold standard for the assessment of liver fibrosis, although it is invasive and can have complications. The present study compares several noninvasive methods of fibrosis assessment in chronic hepatitis C (CHC), including acoustic radiation force impulse (ARFI) elastography, aspa...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2014.909528

    authors: Silva Junior RG,Schmillevitch J,Nascimento Mde F,Miranda ML,Brant PE,Schulz PO,Vieira A,Szutan LA

    更新日期:2014-08-01 00:00:00

  • Patterns of gastrin components in serum during feeding in normal subjects and duodenal ulcer patients.

    abstract::The contribution of the different gastrin components to the gastrin response to a protein-rich meal was studied. Pooled or individual samples of venous blood drawn at intervals in 12 normal subjects and 16 patients with duodenal ulcers were fractionated on Sephadex G 50 superfine columns of various lengths. Total gast...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Stadil F,Rehfeld JF,Christiansen LA,Malmström

    更新日期:1975-01-01 00:00:00

  • Transjugular intrahepatic portosystemic shunt placement for refractory ascites: a single-centre experience.

    abstract:BACKGROUND:The presence of refractory ascites is a common indication for transjugular intrahepatic portosystemic shunt (TIPS). Different models have been proposed for the prediction of survival after TIPS. The aim of this study was to evaluate the predictive factors associated with patients' survival after TIPS placeme...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.703239

    authors: Lodato F,Berzigotti A,Lisotti A,Azzaroli F,Mosconi C,Giampalma E,Renzulli M,Cappelli A,Buonfiglioli F,Calvanese C,Zoli M,Golfieri R,Mazzella G

    更新日期:2012-12-01 00:00:00

  • Responses of anal constipation to biofeedback treatment.

    abstract:OBJECTIVE:Biofeedback is considered an effective treatment for anal constipation, but a substantial proportion of patients fail to improve. Our aim was to identify the key predictors of outcome using a comprehensive standardized evaluation of anorectal function. MATERIAL AND METHODS:We retrospectively analysed the cli...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410009348

    authors: Fernández-Fraga X,Azpiroz F,Casaus M,Aparici A,Malagelada JR

    更新日期:2005-01-01 00:00:00

  • Cholecystokinin in the regulation of gastric acid and endocrine pancreatic secretion in humans.

    abstract::In this study, a selective antagonist of cholecystokinin (CCK)-A receptors, loxiglumide, was used to evaluate the role of CCK in the control of the release of gastrin and pancreatic hormones (insulin, glucagon, pancreatic polypeptide (PP), and somatostatin) after stimulation with exogenous CCK and ingestion of a stand...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529309098239

    authors: Konturek JW,Stoll R,Gutwinska-Konturek M,Konturek SJ,Domschke W

    更新日期:1993-05-01 00:00:00

  • Ultrasonography, 99mTc-DIDA cholescintigraphy, and infusion tomography in the diagnosis of acute cholecystitis.

    abstract::Ultrasonography, 99mTc-DIDA cholescintigraphy, and infusion tomography of the gallbladder were compared in a prospective study comprising 45 consecutive patients clinically suspected of having acute cholecystitis. The diagnosis of acute cholecystitis was established or excluded by operation in 35 patients, by oral cho...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528209181047

    authors: Pedersen JH,Hancke S,Christensen B,Gammelgaard J,Haubek A,Jensen LI,Munck O,Wied U

    更新日期:1982-01-01 00:00:00

  • Patients with cyclic vomiting pattern and diabetic gastropathy have more migraines, abnormal electrogastrograms, and gastric emptying.

    abstract:OBJECTIVE:Some patients with diabetic gastroparesis exhibit cyclical symptoms. The purpose of this work was to study the subset of patients with cyclic vomiting characteristics, described as a cyclic vomiting pattern, in a population of patients with symptoms of diabetic gastroparesis. MATERIAL AND METHODS:Sixty-seven...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802085411

    authors: Christensen CJ,Johnson WD,Abell TL

    更新日期:2008-01-01 00:00:00

  • Analysis of direct medical care costs of peptic ulcer disease in a Korean tertiary medical center.

    abstract:OBJECTIVES:There have been no reported data on the medical care cost of idiopathic peptic ulcer disease (PUD) compared with H. pylori (+) and/or NSAID (+) cases although H. pylori-negative idiopathic ulcers are increasing. The aim of this study was to investigate the direct medical care costs of PUD based on whether it...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2011.639083

    authors: Kang JM,Seo PJ,Kim N,Lee BH,Kwon J,Lee DH,Jung HC

    更新日期:2012-01-01 00:00:00

  • Idiosyncratic drug allergic phenprocoumon-induced hepatitis with subacute liver failure initially misdiagnosed as autoimmune hepatitis.

    abstract:BACKGROUND:Coumarin anticoagulants are known to cause hepatotoxicity, but only a few cases have been reported. Coumarins are usually administered following cardiovascular surgery and the differential diagnosis is post-transfusion hepatitis. METHODS:We report the case of a 46-year-old woman who presented with jaundice,...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201300192076

    authors: Hinrichsen H,Lüttges J,Klöppel G,Fölsch UR,Schmidt WE

    更新日期:2001-07-01 00:00:00

  • Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia.

    abstract:BACKGROUND:Helicobacter pylori gastritis is usually a lifelong disease which can cause different topographical inflammatory reactions and induce divergent effects on acid secretion in humans. High acid output and antrum-predominant gastritis are associated with duodenal ulcer disease, whereas corpus-predominat gastriti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Koskenpato J,Färkkilä M,Sipponen P

    更新日期:2002-07-01 00:00:00

  • Health-related quality of life after ileal J-pouch-anal anastomosis for ulcerative colitis: long-term results.

    abstract:BACKGROUND:This questionnaire study examined associations between health-related quality of life and long-term follow-up results with J-pouch anal anastomosis for ulcerative colitis. METHODS:A two-part questionnaire was sent to patients treated for ulcerative colitis by handsewn J-pouch-anal anastomosis at our institu...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655299750026065

    authors: Tiainen J,Matikainen M

    更新日期:1999-06-01 00:00:00

  • Effect of budesonide enema on remission and relapse rate in distal ulcerative colitis and proctitis.

    abstract:BACKGROUND:Glucocorticosteroid enemas are equally effective as 5-ASA enemas in the treatment of active distal ulcerative colitis (UC). With the introduction of budesonide, the risk of systemic side effects may be reduced. We investigated whether budesonide enema, 2 mg/100 ml, administered twice daily (b.i.d.) could inc...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/00365520212512

    authors: Lindgren S,Löfberg R,Bergholm L,Hellblom M,Carling L,Ung KA,Schiöler R,Unge P,Wallin C,Ström M,Persson T,Suhr OB

    更新日期:2002-06-01 00:00:00

  • Metronidazole in Crohn's disease. A double blind cross-over clinical trial.

    abstract::Twenty-two patients with active Crohn's disease treated with salazosulfapyridin or prednisone, were in addition given metronidazole 1.000 mg daily or placebo for two months each in a double-blind cross-over study. No statistically significant effect was observed on the overall clinical condition in the 20 patients who...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365527809179816

    authors: Blichfeldt P,Blomhoff JP,Myhre E,Gjone E

    更新日期:1978-01-01 00:00:00

  • Predictors of quality-of-life after ileal pouch-anal anastomosis in patients with ulcerative colitis.

    abstract:OBJECTIVES:Predictors of the postoperative quality of life (QoL) following ileal pouch anal anastomosis (IPAA) have not been thoroughly investigated. This study was planned to assess the postoperative QoL following IPAA and to identify its predictors using the 15D instrument. MATERIALS AND METHODS:A retrospective coho...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1337218

    authors: Abolfotouh S,Rautio T,Klintrup K,Helavirta I,Mäkelä J

    更新日期:2017-10-01 00:00:00

  • Response to an extra dose of hepatitis B vaccine and specific antibody persistence in non-responders to primary immunization.

    abstract:BACKGROUND:In a campaign to vaccinate health care workers, a three-dose schedule (0, 1, and 6 months) and a four-dose schedule (0, 1, 2, and 14 months) with hepatitis B (HB) vaccine were used. After primary immunization 26 subjects vaccinated with the 3-dose schedule and 4 subjects vaccinated with the 4-dose schedule h...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529509089796

    authors: Chiaramonte M,Ngatchu T,Majori S,Baldo V,Moschen ME,Renzulli G,Trivello R

    更新日期:1995-06-01 00:00:00

  • Extended lamivudine consolidation therapy in hepatitis B e antigen-positive chronic hepatitis B patients improves sustained hepatitis B e antigen seroconversion.

    abstract:OBJECTIVES:Longer lamivudine (LAM) consolidation therapy after hepatitis B e antigen (HBeAg) seroconversion has been demonstrated to reduce the cumulative relapse rate. However, the optimal interval of LAM consolidation therapy remains controversial. We evaluated the post-treatment durability of LAM-induced HBeAg seroc...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365520903394550

    authors: Kuo YH,Chen CH,Wang JH,Hung CH,Tseng PL,Lu SN,Changchien CS,Lee CM

    更新日期:2010-01-01 00:00:00