Responses of anal constipation to biofeedback treatment.

Abstract:

OBJECTIVE:Biofeedback is considered an effective treatment for anal constipation, but a substantial proportion of patients fail to improve. Our aim was to identify the key predictors of outcome using a comprehensive standardized evaluation of anorectal function. MATERIAL AND METHODS:We retrospectively analysed the clinical and physiological data of 148 patients consecutively treated for constipation due to functional outlet obstruction by biofeedback. Clinical evaluation was performed by means of a structured questionnaire. Anorectal evaluation included anal pressure, neural reflexes, defecatory dynamics, rectal compliance, rectal sensitivity and balloon expulsion test. Biofeedback treatment was performed using a manometric technique. The clinical response to biofeedback treatment was evaluated as good (improvement of constipation) or poor (no improvement or worsening). RESULTS:Of the 148 patients included, 112 (86 F, 26 M; age range 8-67 years) were followed-up for between 1 and 44 months, and 66% had a good response to treatment. The response depended on the severity of the defecatory dysfunction. Thus, lack of anal relaxation during straining and inability to evacuate a 1 ml intrarectal balloon were inversely related to physiological variables related to therapeutic success. Among the 49 patients with absent anal relaxation, 51% had a good response to treatment (versus 78% in patients with partial relaxation; p < 0.01), and among the 29 patients with failed balloon expulsion, 48% responded to treatment (versus 74% in patients able to evacuate > or = 1 ml intrarectal balloon; p < 0.05). CONCLUSIONS:Even in the presence of negative predictors, biofeedback is a valuable treatment option in a substantial proportion of constipated patients.

journal_name

Scand J Gastroenterol

authors

Fernández-Fraga X,Azpiroz F,Casaus M,Aparici A,Malagelada JR

doi

10.1080/00365520410009348

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

20-7

issue

1

eissn

0036-5521

issn

1502-7708

journal_volume

40

pub_type

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