Abstract:
BACKGROUND:Maintaining disease remission throughout pregnancy in women with inflammatory bowel disease is of the utmost importance to decrease the risk of adverse outcome. In general, corticosteroids are safe to use during pregnancy, but no data exist in the specific use of budesonide MMX. We report four cases of budesonide MMX in pregnancy and pregnancy outcome. METHODS:Four women with inflammatory bowel disease experienced disease activity during pregnancy. They were treated with budesonide MMX in an attempt to obtain clinical remission. Disease activity was assessed through physician's global assessment as well as lower endoscopy. RESULTS:Budesonide MMX proved effective in achieving remission in three out of four women. One woman had an uncomplicated colectomy in the second trimester. All children were born normal for gestational age, with no congenital abnormalities and have reached all their developmental milestones. The four children have received vaccines according to the national immunization program without complications. CONCLUSION:No adverse pregnancy outcomes were reported after the use of budesonide MMX. To our knowledge, this is the first report on the safety of budesonide MMX treatment in pregnant women with inflammatory bowel disease.
journal_name
Scand J Gastroenteroljournal_title
Scandinavian journal of gastroenterologyauthors
Vestergaard T,Jørgensen SMD,Christensen LA,Julsgaard Mdoi
10.1080/00365521.2018.1533583subject
Has Abstractpub_date
2018-12-01 00:00:00pages
1459-1462issue
12eissn
0036-5521issn
1502-7708journal_volume
53pub_type
杂志文章abstract::This study evaluates the endoscopic manometric findings within the sphincter of Oddi (SO) in nine healthy volunteers premedicated with atropine 1 h before and with diazepam during the investigation. We measured the bile duct sphincter in seven persons and the pancreatic duct sphincter in two. A hydraulic capillary inf...
journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章
doi:10.3109/00365528708991887
更新日期:1987-03-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
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doi:10.3109/00365520903358899
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journal_title:Scandinavian journal of gastroenterology
pub_type: 杂志文章,多中心研究
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abstract::For three years (1970-72) endoscopic gastric biopsies from 883 lesions in 862 patients were histologically examined, every single biopsy (4088) separately. In 38% of the cases, namely 142 malignant and 194 benign lesions, the diagnoses could be verified. If the criterion for a positive examination was that one of the ...
journal_title:Scandinavian journal of gastroenterology
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journal_title:Scandinavian journal of gastroenterology
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更新日期:2019-01-01 00:00:00
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journal_title:Scandinavian journal of gastroenterology
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更新日期:2017-09-01 00:00:00
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doi:10.3109/00365529009095535
更新日期:1990-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Scandinavian journal of gastroenterology
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journal_title:Scandinavian journal of gastroenterology
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journal_title:Scandinavian journal of gastroenterology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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